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Predictors of heart rhythm disturbances in hypertensive obese patients with obstructive sleep apnea

Journal of Geriatric Cardiology 2017年第9期14卷 553-562页

作者： lyudmila sergeevna korostovtseva Nadezhda Edvinovna Zvartau Oxana Petrovna Rotar Yurii Vladimirovich Sviryaev Aleksandra Olegovna Konradi Research Department for Hypertension Almazov National Medical Research Centre St Petersburg Russia Institute of TranslationalMedicine ITMO University St Petersburg Russia

Objective To assess the incidence and predictors of heart rhythm and conduction disturbances in hypertensive obese patients with andwithout obstructive sleep apnea （OSA）. Methods This is an open, cohort, prospective study. Out of 493 screened patients, we selected 279hypertensive, obese individuals without severe concomitant diseases： 75 patients without sleep-disordered breathing （non-SDB group）, and204 patients with OSA （OSA group）. At baseline, all patients underwent examination, including ECG, Holter ECG monitoring, and sleepstudy. During follow-up （on 3, 5, 7 and 10th years; phone calls once per 6 months）, information about new events, changes in therapy and lifestyle was collected, diagnostic procedures were performed. As the endpoints, we registered significant heart rhythm and conduction disordersas following： atrial fibrillation （AF）, ventricular tachycardia, atrioventricular block （AV） 2-3 degree, sinoatrial block, significant sinus pauses（〉 2000 ms）, and the required pacemaker implantation. Results The median follow-up was 108 （67.5-120） months. The frequency of heartrhythm disorders was higher in OSA patients （29 cases, X^2= 5.5; P = 0.019） compared to the non-SDB patients （three cases; OR： 3.92, 95%CI： 1.16-13.29）. AF was registered in 15 patients （n = 12 in OSA group; P = 0.77）. Heart conduction disturbance developed in 16 patients,without an association with the rate of coronary artery disease onset. Regression analysis showed that only hypertension duration was anindependent predictor olAF （OR： 1.10, 95% CI： 1.04-1.16; P = 0.001）. In case of heart conduction disturbances, apnea duration was thestrongest predictor （P = 0.002）. Conclusions Hypertensive obese patients with OSA demonstrate 4-fold higher incidence of heart rhythmand conduction disturbances than subjects without SDB. Hypertension duration is an independent predictor for AF development, while sleepapneaJhypopnea duration is the main factor for heart conduction disorders onset in hypertensiv

关键词： Atrial fibrillation Cardiovascular morbidity Cardiovascular prognosis Heart conduction disorder Obstructive sleep apnea

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Impact of In^(3+) cations on structure and electromagnetic state of M-type hexaferrites

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Journal of Energy Chemistry 2022年第6期31卷 667-676,I0018页

作者： Vitalii Alexandrovich Turchenko Sergei Valentnovich Trukhanov Vladmir Grigor'evich Kostishin Francua Damay Florance Porcher Denis Sergeevich Klygach Maxim Grigor'evich Vakhitov lyudmila Yur'evna Matzui Olena sergeevna Yakovenko Bernat Bozzo Ignasi Fina Munirah Abdullah Almessiere Yassine Slimani Abdulhadi Baykal Di Zhou Alex Valentinovich Trukhanov Joint Institute for Nuclear Research 6 Joliot-Curie Str.Dubna 141980Russia South Ural State University 76Lenin Av.Chelyabinsk 454080Russia Donetsk Institute of Physics and Technology named after O.O.Galkin of the NASU 46 Nauki Av.Kiev 03680Ukraine SSPA“Scientific and Practical Materials Research Centre of NAS of Belarus” 19 P.Brovki str.Minsk 220072Belarus National University of Science and Technology“MISiS” Leninsky av.4Moscow 119049Russia Laboratoire Leon Brillouin UMR12 CEA-CNRSB̂at.563 CEA SaclayGif sur YvetteCedex 91191France Ural Federal University named after the First President of Russia B.N.Yeltsin Yekaterinburg 620002Russia Taras Shevchenko National University of Kyiv Volodymyrs’ka str.64/13Kyiv 01601Ukraine Institut de Ciencia de Materials de Barcelona-CSIC Campus de la UABBellaterraBarcelona 08193Spain Department of Biophysics Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam 31441Saudi Arabia Department of Nanomedicine Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam 31441Saudi Arabia Electronic Materials Research Laboratory Key Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic Science and EngineeringXi’an Jiaotong UniversityXi'an 710049ShannxiChina Department of Physics College of ScienceImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam 31441Saudi Arabia

The solid solutions of In^(3+) doped M-type strontium hexaferrites were produced using a conventional solid-state reaction method,and Rietveld analysis of the neutron diffraction patterns was ***^(3+) cations occupy octahedral (4f_(Ⅵ)and 12 k) and tetrahedral (4f_(Ⅳ)) positions (SG=P6_(3)/mmc(No.194)).The average particle size is 837–650 *** tempearature (T_(C)) of the compounds monotonically decreased down to~520 K with increasing x.A frustrated magnetic state was detected from ZFC and FC *** magnetization (M_(s)) and effective magnetocrystalline anisotropy coefficient (k_(eff)) were determined using the law of approach to saturation.A real permittivity (ε″) maximum of~3.3 at~45.5 GHz and an imaginary permittivity (ε′) of~1.6 at~42.3 GHz were observed for x=0.1.A real permeability (μ′) maximum of~1.5 at~36.2 GHz was observed for x=0.Aμ″imaginary permeability maximum of~0.8 at~38.3 GHz was observed for x=*** interpretation of the results is based on the type of dielectric polarization and the natural ferromagnetic resonance features.

关键词： Doped strontium hexaferrites Neutron powder diffraction Magnetic properties Permittivity Permeability

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