检索结果-南通市图书馆

Botulinum Toxin A, Effect on Tensile Strength of Skin Wounds;Animal Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2020年第2期8卷 17-24页

作者： Carlos A. Gonzalez-Alvarado Juan Garzon-Muvdi Roxanna Perez-Garmendia Victoria Ramirez luz Graciela Cervantes Adriana Rodriguez-Gomez Rodrigo Davila-Diaz Cuahutemoc Marquez-Espriella Plastic and Reconstructive Surgery Division Hospital Central Sur de alta Especialidad de Petroleos Mexicanos Mexico City Mexico Experimental Surgery Department Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran Mexico City Mexico Pharmacology Department Instituto Nacional de Cardiologia Ignacio Chavez Mexico City Mexico Pathology Department Hospital Angeles del Pedregal Mexico City Mexico

Wound healing and cicatrization is a process that involves several phases. The main goal of a surgeon and specially the plastic surgeon is to achieve the best cosmetic results and avoid complications. Several tools are available to achieve the best result. One of the tools recently studied is the use of Botulinum toxin. The use of Botulinum toxin has showed to be a useful aid by improving macroscopic cosmetic changes, as histopathologic ones. The increase of the tensile strength is also one of the positive changes that come with the use of botulinum toxin.

关键词： Botulinum Toxin Wound Tensile Strength

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

不使用氢氟酸的全瓷修复技术

中国口腔医学继续教育杂志 2017年第6期20卷 341-345页

作者： Bergoli CD de Carvalho RF luz JN luz MS Meincke DK Saavedra Gde S 杨任李煌韩宁宁不详南京大学医学院附属口腔医院南京市鼓楼区中央路30号南京市口腔医院210000

目的：参照修复说明书，分别在使用氢氟酸和不使用氢氟酸的条件下，通过热循环老化实验．评估复合树脂与长石质瓷之间额粘接强度。材料和方法：将48块玻璃长石质瓷块（8．8．6mm）根据它们不同的表面处理方式分为3组：110％氢氟酸＋Sig... 详细信息

目的：参照修复说明书，分别在使用氢氟酸和不使用氢氟酸的条件下，通过热循环老化实验．评估复合树脂与长石质瓷之间额粘接强度。材料和方法：将48块玻璃长石质瓷块（8．8．6mm）根据它们不同的表面处理方式分为3组：110％氢氟酸＋Signum陶瓷底涂剂I＋Signum陶瓷底涂剂Ⅱ（对照组）;2橡胶磨石＋Signum陶瓷底涂剂I＋Signum陶瓷底涂剂Ⅱ（实验组）；***陶瓷底涂剂I＋Signum陶瓷底涂剂Ⅱ（阴性对照组）。每个瓷块经表面处理后堆塑复合树脂，然后将瓷-复合树脂切割成条状（粘结区域=1mm^2）。将每组中-半的瓷-复合树脂条分别在5度和55度的水温下浸没30s．进行老化循环6000次，中间转换时间为2s。同时，对剩下的-半瓷-复合树脂条进行微拉伸粘结强度试验。对每个瓷块的平均粘结强度数据进行记录，并进行Two-wayANOVA分析和Tukey’s检验（a=005）。结果：老化实验对所有试验组瓷块的粘结强度数值都有显著影响（p=0．000）。未进行老化试验组的瓷块粘结强度数值最高，其中第一组为13．1±25MPa．第二组为11．5±5．1MPa。结论：老化试验影响到了所有组粘结界面的粘结强度。用橡胶磨石打磨，且未使用氢氟酸的表面处理组（第二组）效果最佳．其粘结强度数值与对照组相似。

关键词：长石质瓷修复玻璃陶瓷陶瓷表面处理.

Sustainability of E-Trike as Alternative Mode of Public Transportation System: The Case of Cabanatuan City, Philippines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Civil Engineering 2017年第3期7卷 362-377页

作者： Felipe E. Balaria Marilou P. Pascual Mercedes D. Santos Arjay F. Ortiz Arneil G. Gabriel Teodora luz Soto Mangahas Nueva Ecija University of Science & Technology Cabanatuan City Philippines

The City of Cabanatuan is dubbed as the “Tricycle Capital of the Philippines”. Tricycle is a three wheeled vehicle used to transport people. Cabanatuan has about 30,000 registered gas-fed four-stroke motorized tricycles. Tricycle operation in this City has become the source of livelihood for around 10,000 families. Its number has tremendously increased despite growing competition and declining net daily income and the adverse effects it brings to the environment. The study analyzed the different aspects in the adoption of E-trikes (electric tricycles) as a mode of public transport system replacing motorized tricycles in the city. The conceptual framework of sustainable development was used to analyze the data. Basic accounting method in determining return on investment and payback period were used to compare the cost and return from among the current mode of transportation as against the adoption of E-trike. Data gathering employed the interviews, survey questionnaires and focus group discussion. The three areas of sustainability measured in the study were economic, socio-political and environmental. The study showed that from among 412 tricycle driver-operators randomly selected, majority were amenable to the shift from engine propelled tricycle to E-trike. However, cost of E-trike deters adoption and full implementation by the City Government. Political issue is also?the?utmost consideration since work displacement is imminent among the stakeholders once adoption of this mode takes place. On the other side, E-trike was found to be sustainable in the long run both on the point of view of operators and the riding public. The paper recommended that policy regulation be laid down, adopted, and implemented by the local government unit in response to the Philippines Cleaner Air Act.

关键词： Motorized Tricycle Electric Tricycle Environmental Hazard Adoption of Available & Better Technologies Sustainability Commercial Viability

Iterative Estimation for Flight Dynamic Helicopter Simulator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mathematics and System Science 2015年第12期5卷 501-508页

作者： Ivana Yoshie Sumida Haroldo F. de Campos Velho Eduardo F. P. da luz Ronaldo V. Cruz Luiz CarlosS. Goes pplied Computing Graduate Program National Institute for Space Research (1NPE) Brazil Flight Test Research Institute (IPEV) Brazil Associated Laboratory for Computing andApplied Mathematics National Institute for Space Research (INPE) Brazil Department of Mechanical Engineering Technological Institute of Aeronautics (ITA) Brazil

Flight simulators can provide a suitable alternative to real flight, mainly to increase safety through the training of crew, and evaluation data from simulator can be used to validation and certification of aircraft systems. However, it must convey some degree of realism to the user to be effective. For that reason, it is necessary to calibrate the simulator software. Calibration for flight simulation is parameter identification process. The process is formulated as an optimization problem, and it is solved by using a new approach named Multiple Particle Collision Algorithm （MPCA）. Results show a good performance for the employed approach.

关键词： Dynamic Flight Parameter Identification Multiple Particle Collision Algorithm

Giant Spinal Schwannomas. Presentation of Two Cases with Interdisciplinary Surgical Resection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Modern Neurosurgery 2023年第1期13卷 1-8页

作者： Carlos Erosa Velázquez Angel Octavio Soto Hernandez Ricardo Cazares Sergio Ivan Reyna Heredia Apolinar de la luz Lagunas Cuauhtemoc Gil-Ortiz Mejia Andres Jaime Aguirre Universidad Nacional Autónoma de México México City México Centro Médico Nacional 20 de Noviembre ISSSTE México City México

Purpose: To report two quite rare cases of giant schwannomas of the cervical and thoracic spine. Surgical resection is usually the treatment of choice for these neoplasms. Methods: The first patient is a 48-year-old male that came to our department, complaining about weakness and paresthesia of both lower extremities and upper left extremity, and a considerably big dorsal palpable lump. MRI and CT scan were used to diagnose giant cervical schwannoma. Because of the intensity of symptoms, he was subjected to surgery. Multidisciplinary resection involving neurosurgical and oncosurgicalteamn was performed for intravertebral and extravertebral approaches. The second patient is a 55-year-old female that came to the hospital complaining about incapacitating pain and dysesthesia involving T6, T7, and T8 dermatomes, with no other deficits. MRI and CT scan were used to diagnose giant thoracic schwannoma. Because of the intensity of the pain, surgery was decided as the treatment of choice. Video assisted thoracoscopic surgery was performed and total resection was achieved, with improvement of the symptoms. Results: Both patients showed complete remission of the symptoms, with no major deficits after surgery. Conclusion: Although infrequent, giant spinal schwannomas may be the cause of visible lumps in the back with radicular symptoms. When asymptomatic, conservative treatment could be viable, but when they present symptoms, surgery offers good results.

关键词： Spinal Schwannomas Giant Schwannomas Interdisciplinary Surgery

MOLECULAR CLONING OF A POU GENE FRAGMENT FROM PECTEN MAXIMUS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

MOLECULAR CLONING OF A POU GENE FRAGMENT FROM PECTEN MAXIMUS

Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation

第十八次国际扇贝大会

作者： Vanessa Lozano Crimgilt Mesías-Gansbiller Roi Martínez-Escauriaza Antonio J.Pazos M.luz Prez-Parall Laboratorio de Biología Molecular y del Desarrollo.Departamento de Bioquímica y Biología Molecular.Instituto de Acuicultura.Universidad de Santiago de Compostela.15782-Santiago de Compostela.Spain

＜正＞Introduction POU proteins are transcriptional regulators containing a bipartite DNA binding domain referred to as the POU *** domain is composed of two highly conserved regions,a N-terminal POU specific domain and a C-terminal POU homeodomain,separated by a non-conserved linker of 15-55 *** domain was initially identified after the simultaneous cloning of three mammalian transcription factors and a Caenorhabditis elegans developmental regulator（1）.The POU-specific subdomain is an approximately 75 amino acid region that can be subdivided further into two highly conserved regions（A and B）.The POU homeodomain is a highly conserved motif of 60 amino acids related to the classic homeodomains.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第34期26卷 5101-5117页

作者： David Fernández-Ramos Fernando Lopitz-Otsoa Laura Delacruz-Villar Jon Bilbao Martina Pagano Laura Mosca Maider Bizkarguenaga Marina Serrano-Macia Mikel Azkargorta Marta Iruarrizaga-Lejarreta Jesús Sot Darya Tsvirkun Sebastiaan Martijn van Liempd Felix M Goni Cristina Alonso María luz Martínez-Chantar Felix Elortza Liat Hayardeny Shelly C Lu JoséM Mato Precision Medicine and Metabolism Laboratory Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160BizkaiaSpain CIBERehd-Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas Madrid 28029Spain Department of Precision Medicine University of Campania"Luigi Vanvitelli"Naples 80138Italy Liver Disease Laboratory Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain Proteomics Platform Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain OWL Metabolomics Derio 48160Spain Instituto Biofisika(UPV/EHU CSIC)Leioa 48940SpainDepartamento de Bioquímica y Biología MolecularUniversidad del País VascoLeioa 48940Spain Pre-clinical and Chemistry Manufacturing and ControlsGalmed PharmaceuticalsTel Aviv 6578317Israel Metabolomics Platform Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain Division of Digestive and Liver Diseases Cedars-Sinai Medical CenterLos AngelesCA 90048United States

BACKGROUND Arachidyl amido cholanoic acid(Aramchol)is a potent downregulator of hepatic stearoyl-CoA desaturase 1(SCD1)protein expression that reduces liver triglycerides and fibrosis in animal models of *** a phase IIb clinical trial in patients with nonalcoholic steatohepatitis(NASH),52 wk of treatment with Aramchol reduced blood levels of glycated hemoglobin A1c,an indicator of glycemic *** To assess lipid and glucose metabolism in mouse hepatocytes and in a NASH mouse model[induced with a 0.1%methionine and choline deficient diet(0.1MCD)]after treatment with *** Isolated primary mouse hepatocytes were incubated with 20μmol/L Aramchol or vehicle for 48 ***,analyses were performed including Western blot,proteomics by mass spectrometry,and fluxomic analysis with 13C-uniformly labeled *** the in vivo part of the study,male C57BL/6J mice were randomly fed a control or 0.1MCD for 4 wk and received 1 or 5 mg/kg/d Aramchol or vehicle by intragastric gavage for the last 2 *** metabolomics were assessed using ultra-high-performance liquid chromatography-time of flight-MS for the determination of glucose metabolism-related *** Combination of proteomics and Western blot analyses showed increased AMPK activity while the activity of nutrient sensor mTORC1 was decreased by Aramchol in *** translated into changes in the content of their downstream targets including proteins involved in fatty acid(FA)synthesis and oxidation[PACCα/β(S79),SCD1,CPT1A/B,HADHA,and HADHB],oxidative phosphorylation(NDUFA9,NDUFB11,NDUFS1,NDUFV1,ETFDH,and UQCRC2),tricarboxylic acid(TCA)cycle(MDH2,SUCLA2,and SUCLG2),and ribosome(P-p70S6K[T389]and P-S6[S235/S236]).Flux experiments with 13Cuniformely labeled glucose showed that TCA cycle cataplerosis was reduced by Aramchol in hepatocytes,as indicated by the increase in the number of rounds that malate remained in the TCA ***,liver metabolomic analysis showed

关键词： Nonalcoholic fatty liver disease Steatohepatitis Methionine and choline deficient diet Tricarboxylic acid cycle Hemoglobin A1c Stearoyl-CoA desaturase 1

教堂中的瑰宝——巴西邦布亚的圣方济亚西西教堂的翻新

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

照明设计 2006年第4期 36-39页

作者： Monica luz Lobo Petra Steinor Jomar Braganca（摄影）李彩歌（译）

以圣方济亚西西（*** of Assisi）命名的小教堂建于1943年，座落在邦布亚（Pampulha）。这座由现代巴西建筑业先驱奥斯卡·尼迈尔（Oscar Niemeyer）设计的小教堂是一块真正的瑰宝。像所有的宝石一样,这个朝拜圣地闪闪发光，魅力四射。... 详细信息

以圣方济亚西西（*** of Assisi）命名的小教堂建于1943年，座落在邦布亚（Pampulha）。这座由现代巴西建筑业先驱奥斯卡·尼迈尔（Oscar Niemeyer）设计的小教堂是一块真正的瑰宝。像所有的宝石一样,这个朝拜圣地闪闪发光，魅力四射。尤其在翻新之后，由于引进了全新的照明理念，教堂更是光彩夺目。人们甚至可以说整个教堂熠熠生辉——就像宝物会神奇地自内向外发光一样。

关键词：教堂翻新巴西建筑业发光

Clinical Facial Study of the Parents of Children with OAV (Oculo-Auriculo-Vertebral) Syndrome. Cases and Controls

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Otolaryngology and Head & Neck Surgery 2020年第2期9卷 53-60页

作者： María de la luz Arenas-Sordo Claudia I. Cruz-Ugalde Eny Paola Linares-Mendoza Julieta Karina Peñ uelas-Romero Beatriz C. Aldape-Barrios Genetics Department Instituto Nacional de Rehabilitación “Luis Guillermo Ibarra Ibarra” Mexico City México School of Dentistry Universidad Nacional Autónoma de México University City Mexico City México

Introduction: The oculo-auriculo-vertebral syndrome is a complex disease of the head and neck. Aim: The purpose of this study was to look for facial asymmetry, measuring both sides of the mandible and external ear in the parents of these patients in a clinical way, to see if it could be considered as a minor manifestation of the disease. Patients and Methods: A clinical, observational study was done with 50 trios and their parents’ controls, at the Instituto Nacional de Rehabilitación LGII in 2019, from January to May. Mandible and ear measurements were done. Results: All of our patients had microtia and facial asymmetry, and in 17 cases, other anomalies. We compared both sides of the mandible in the patients’ parents and in the parents’ controls. The results showed differences only in the fathers, and in the comparison with the controls, we found statistical differences only in women, family and non-family cases. The ears did not show any differences. Discussion: It is very interesting that we found differences in the measurements of the mandible of the patients’ mothers and their controls;in the mothers the mandible was bigger than in the controls, this probably means that the development of the cranial structures is modified by some genetic variants. No differences were found in the measurements of the ears. Conclusion: It is very difficult to know exactly if the differences we found are important or not. The clinical measurements could be a good option to establish if the parents have minor manifestations that could explain some heritability.

关键词： Oculo-Auriculo-Vertebral Syndrome Microtia Facial Asymmetry