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Therapeutic and biological activities of Calotropis procera(Ait.) ***.

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 332-336页

作者： Marcia Calheiros Chaves Silva Antonio Batista da Silva Fabiano Moura Teixeira Paulo Cesar Pereira de Sousa Regina Maria Macedo Rondon Jose eduardo Ribeiro Honorio Junior luiz Rafael Leite Sampaio Samanda Lima oliveira Angela Nadyla martins Holonda Silvania Maria Mendes de Vasconcelos Enfermeira Mestre em Farmacologia/Universidade Federal do Ceara/UFC Farmaceutico Mestre em Patologia Tropical/Universidade Federal do Amazonas/UFAM Biologo Mestre em Bioquimica/Universidade Federal do Ceara/UFC Farmaceutico Mestre em Ciencias Farmaceutica/Universidade Federal do Ceara/UFC Biologa Mestre em Producao Animal/Universidade Estadual do Ceara/UECE Biologo Mestre em Fisiologia da Universidade Estadual do Ceara/UECE Enfermeiro Mestrando em Farmacologia da Universidade Federal do Ceara/UFC Aluna de Farmacia da Universidade Federal do Ceara/UFC Enfermeira Professora Adjunto do Depto.de Fisiologia e Farmacologia da Universidade Federal do Ceara/UFC

Medicinal plants have been used to treat various ailments of the poor population around the world;hence the interest among researchers to know the active ingredients of certain plants has being *** Calotropis procera(***) is a plant original from Africa,commonly found in northeastern *** is well known for their pharmacological properties,since it produces large amounts of *** important role that medicinal plants play in folk medicine has led us to develop this article in order to review the major pharmacological activities of C. procera.

关键词： Calotropis procera Pharmacological activity Medicinal plants

Splenectomy in Patient with Splendid Cysts

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Journal of Biosciences and Medicines 2018年第5期6卷 120-125页

作者： Viní cius Moreira Paladino Thiago Sande Miguel Dé bora Trindade martins Nayrton Kalys Cruz dos Anjos Fernando Antonio galvã o Pereira Junior Marcia Machado galvã o Pereira Carolina galvã o Teixeira Vinicius Sande Miguel Bruna Sande Miguel Daniel Almeida da Costa The Medical School at the Center of Higher Education of Valen& amp ccedil a Valen&amp amp ccedil a Brazil Suprema Medical School Juiz de Fora Brazil Universidade Grande Rio Medical School Rio de Janeiro Brazil

Introduction: Splenic cysts are uncommon and usually do not generate signs and symptoms, being diagnosed by incidental findings. Case report: A 35-year-old, female patient attended the luiz Gioseffi Jannuzzi School Hospital (HELGJ) presenting episodes of vomiting and abdominal pain in the left hypochondrium. She was hospitalized for diagnostic investigation. Computed tomography showed the splenic cyst. The procedure was the surgical approach by laparotomy with splenectomy. Histopathological confirmed the diagnosis. Discussion: Compared to the scarce reports in literature, the case described presented typical epidemiology and clinical features. Conclusions: Given the rarity of this pathology cases, it is essential to report these in order to elucidate the specificities and also to discuss diagnostic and therapeutic methods.

关键词： Splenectomy Splendid Cysts Abdominal Pain

Infrared Spectroscopy of Titania Sol-Gel Coatings on 316L Stainless Steel

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Materials Sciences and Applications 2011年第10期2卷 1375-1382页

作者： Daniela Cordeiro Leite Vasconcelos Vilma Conceicao Costa eduardo Henrique martins Nunes Antonio Claret Soares Sabioni Massimo Gasparon Wander luiz Vasconcelos Department of Metallurgical and Materials Engineering Federal University of Minas GeraisBelo HorizonteBrasil Department of Physics Federal University of Ouro PretoOuro PretoBrasil School of Earth Sciences The University of QueenslandSt.LuciaAustralia

Sol-gel titania films were deposited on 316L stainless steel using titanium isopropoxide as a chemical precursor. Dip-coating was performed at withdrawal speeds of 6 mm/min, 30 mm/min, and 60 mm/min. Deposited gel films were heat treated in air at 80℃, 100℃, 300℃, and 400℃. The structural evolution of the coatings was evaluated by infrared reflection-absorption spectroscopy. The influence of the withdrawal speed and the heat treatment temperature on the structure of the films was studied by varying the reflectance incidence angle during the infrared experiments and by Glow Discharge Spectrometry. Free functional groups were detected. The results indicate the formation of bidendate bridging coordination of carboxylic acid to titanium. Titanium atoms can also be pentacoordinated according to the processing conditions of the films. We observed a tendency of increasing amounts of oH groups with decreasing reflectance incidence angle. The film hardness was measured via Knoop microindenation hardness test.

关键词： Films Sol-Gel Infrared Spectroscopy Glow Discharge Spectrometry Knoop Hardness

Human Seroreactivity to Secreted Molecules of Corynebacterium pseudotuberculosis

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Advances in Microbiology 2022年第3期12卷 150-158页

作者： Ramon Mendes dos Santos Silvânia Maria Andrade Cerqueira Caio Lopez Borge Andrade Gabriel Saldanha Müller Vitória Costa de Menezes Santos Hévlyn Ribeiro de Araújo Samanta Queiroz Rogério Reis Conceição luiz Gustavo Freitas oliveira Marcos Borges Ribeiro Silvana Marchioro Lilia Ferreira de Moura-Costa Fúlvia Soares Campos de Sousa Maria da Conceição Aquino de Sá José Tadeu Raynal Rocha Filho Soraya Castro Trindade eduardo martins Netto Roberto Meyer Songelí Menezes Freire Laboratory of Immunology and Molecular Biology of the Health Sciences Institute of the Federal University of Bahia Bahia Brazil Specialized Hospital otávio Mangabeira Bahia Brazil Microbiology of the Federal University of Bahia Bahia Brazil Laboratory of Infectology of the University Hospital Complex Professor Edgard Santos Salvador Bahia Brazil

Corynebacterium pseudotuberculosis is an infectious agent that occurs in small ruminants causing caseous lymphadenitis, and more rarely in humans causing lymphadenitis and pneumonia. The breeding small ruminants have great economic importance in Brazil. Rural farm workers and veterinary students who acquired this disease suffered from weakening symptoms for weeks, and the identification of the etiological agent was time-consuming and complex. Due to the low prevalence of case records, there is probably no available commercial diagnostic kit for C. pseudotuberculosis infection in humans. This study aimed to describe human seroreactivity to secreted antigens from C. pseudotuberculosis. Reactivity of serum from farm workers (n = 14), individuals who work with the bacillus at laboratory (n = 8) or individuals without contact (n = 25) was tested with secreted proteins from PAT10 strain of C. pseudotuberculosis by Western blotting. Samples of all (100%) farm workers showed reactivity to 31 kDa, 71 kDa and 164 kDa proteins, while laboratory workers showed 87.5%, 62.5 % and 37.5%, and no-contact 20%, 0% and 16%, respectively. All sera recognized the 275 kDa protein. our data suggest that C. pseudotuberculosis secreted proteins are antigenic in humans and the recognition profiles allowed the identification of individuals with and without prior contact with this bacillus. This is the first paper which describes human reactivity to C. pseudotuberculosis in serum samples of workers in Brazil.

关键词： Human Immunoreactivity Antigenicity Corynebacterium pseudotuberculosis Secreted Proteins Western Blot

Temporomandibular Disorder in University Students of the Parque das Rosas Campus, Universidade Estácio de SáThat Practice Sports

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Health 2016年第1期8卷 18-23页

作者： Rosineli Paz Cabral Manuel eduardo Moiolli-Rodrigues Flávia Lima Kleinsorgen Motta Francisco Carlos Kleinsorgen de Souza Motta Juliana Rocha da Silva Larissa Malheiros Neide martins Leonardo Trepte André luiz G. Abrão Adalgisa Maiworm luiz Carlos oliveira Raphael Lemgruber Cardoso Adriano Arnóbio Giuseppe Antonio Presta Danúbia da Cunha de Sá Caputo Sebastião David Santos Filho Éric Heleno F. F. Frederico Mario Bernardo-Filho Severo de Paoli Universidade Estácio de Sá—Campus R9—GEPS R9 Rio de Janeiro Brasil Universidade Estácio de Sá—Campus Parque das Rosas Rio de Janeiro Brasil Departamento de Biofísica e Biometria Instituto de Biologia Roberto Alcantara Gomes Universidade do Estado de Rio de Janeiro Rio de Janeiro Brasil Programa de Pós-Graduacao em Fisiopatologia Clínica e Experimental Faculdade de Ciências Médicas Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil UniFacex—Centro Universitário do Facex Natal Brasil Programa de Pós-Graduacao em Biociências Instituto de Biologia Roberto Alcantara Gomes Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil

The stomatognathic system (SS) is a functional unit of the body that depends on the balance of several tissues. It consists of various structures, including the temporomandibular joint. Temporomandibular disorder (TMD) can occur due to alterations in the SS. The Fonseca Anamnestic Index (FAI) is a scale used to evaluate and to characterize the TMD Type: no DTM, mild, moderate and severe. The aim is to evaluate the prevalence of signs and symptoms related to TMD in university students of the Parque das Rosas Campus, Universidade Estácio de Sá that practice sports. This investigation was approved (CAAE number 325678413.9.0000.5284). Two hundred eighth students (110 male and 98 female, aged 19 - 35 years) accepted to be in this investigation. All the participants answered a General Questionnaire (GQ) and the FAI. The GQ had questions about the age, sex and the presence of TMD. The FAI was used. A statistical difference (p > 0.05) was not found about the presence of TMD. Among the female, an elevated number of the students with signal or symptoms related to the temporomandibular with statistic significance (p observed. In the population without TMD, the prevalence of this disorder is higher between male than female. Considering the FAI, among the female students, there is a prevalence of the Mild Type. Considering the evaluation of the type of TMD among the male and female students no difference was found between male and female to the types mild and moderate, however, the prevalence of the severe Type is higher in female than in male with statistical significance. In conclusion, TMD is a relevant clinical condition with an important prevalence among the university students. Moreover, the type of the TMD could be considered due to prevalence of the Type Severe among the women.

关键词： Temporomandibular Disorder University Student Fonseca Anamnestic Index Prevalence

Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil

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World Journal of Gastroenterology 2020年第25期26卷 3611-3624页

作者： Valéria Cristina Loureiro Salgado Ronir Raggio luiz Neio Lucio Fernandes Boéchat Isabella Sued Leao Bianca do Carmo Schorr JoséMiguel Luz Parente Daniela Calado Lima eduardo Santos Silveira Júnior Genoile oliveira Santana Silva Neogélia Pereira Almeida Andrea Vieira Maria luiza Queiroz de Bueno Júlio Maria Chebli érika Ruback Bertges Luísa martins da Costa Brugnara Columbano Junqueira Neto Stefania Burjack Gabriel Campbell Luana Letiza Discacciati Joao Paulo Silva Cézar Tiago Nunes Gilaad G Kaplan Cyrla Zaltman Division of Gastroenterology Department of Internal MedicineClementino Fraga Filho HospitalFederal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Institute for Studies in Public Health Federal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Multidisciplinary Research Laboratory Clementino Fraga Filho HospitalInstitute of Thoracic DiseasesFaculty of MedicineFederal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Division of Gastroenterology Department of Internal MedicineHospital UniversityFaculty of MedicineFederal University of PiauíPiauí64049-550Brazil Almeida Division of GastroenterologyInflammatory Bowel Disease Outpatient ClinicRoberto Santos General Hospital(HGRS)of the Bahia State Department of HealthBahia 40110-060Brazil Division of Gastroenterology Inflammatory Bowel Disease Outpatient ClinicIrmandade Santa Casa da Misericórdia of São PauloSão Paulo 01221020Brazil Division of Gastroenterology Department of Internal MedicineHospital UniversityFaculty of MedicineFederal University of Juiz de ForaMinas Gerais 36036-247Brazil Division of Gastroenterology Inflammatory Bowel Disease Outpatient ClinicFederal District Base HospitalBrasília 70330-150Brazil Gastrointestinal Physiology Institute of Nutritional ScienceNestle Research CenterLausanne 1000Switzerland Departments of Medicine and Community Health Sciences University of CalgaryCalgary T2N4Z6Canada

BACKGRoUND The etiology of inflammatory bowel disease(IBD)is unknown,but it is believed to be *** hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated *** To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development *** A multicenter case-control study was carried out with 548 Crohn’s disease(CD)and 492 ulcerative colitis(UC)outpatients and 416 healthy controls,from six IBD centers within different Brazilian states at diverse socioeconomic development stages.A semi-structured questionnaire with 87 socioeconomic and environmental questions was *** regression model was created to assess the odds ratio(oR)with P value and 95%confidence intervals(CI).RESULTS Predictive variables for both diseases(CD and UC)were women[odd ratios(oR)=1.31;oR=1.69],low monthly family income(oR=1.78;oR=1.57),lower number of cohabitants(oR=1.70;oR=1.60),absence of vaccination(oR=3.11;oR=2.51),previous history of bowel infections(oR=1.78;oR=1.49),and family history of IBD(oR=5.26;oR=3.33).Associated risk factors for CD were age(18-39 years)(oR=1.73),higher educational level(oR=2.22),absence of infectious childhood diseases(oR=1.99).The UC predictive variables were living in an urban area(oR=1.62),inadequate living conditions(oR=1.48)and former smokers(oR=3.36).Appendectomy was a risk factor for CD(oR=1.58)with inverse association with UC(oR=4.79).Consumption of treated and untreated water was associated with risk of CD(oR=1.38)and UC(oR=1.53),*** This is the first examining environmental exposures as risk factors for inflammatory bowel disease in *** of the variables associated with disease risk support the role of the hygiene hypothesis in IBD development.

关键词： Crohn’s disease Ulcerative colitis Risk factors Environmental factors Hygiene hypothesis