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Nanostructured 3-D Collagen/Nanotube Biocomposites for Future Bone Regeneration Scaffolds

Nano Research 2009年第6期2卷 462-473页

作者： Edelma E.da Silva Heloisa H.M.Della Colleta Andre S.Ferlauto Roberto L.Moreira Rodrigo R.Resende Sergio oliveira Gregory T.Kitten Rodrigo G.Lacerda luiz o.ladeira Universidade Federal de Minas Gerais Departamento de FísicaLaboratório de NanomateriaisAv.Antônio Carlos662730123-970Belo HorizonteMGBrazil Universidade Federal de Minas Gerais Departamento de MorfologiaAv.Antônio Carlos662730123-970Belo HorizonteMGBrazil

The fi eld of bionanotechnology has been rapidly growing during the last few years and we can now envision a controllable integration between biological and artificial matter,where new biomimetic structures with a wide range of chemical and physical properties will promote the development of a novel generation of medical *** this work we describe a collagen/carbon nanotube composite which has the potential to be used as a scaffold for tissue *** this biocomposite incorporates the advantageous properties of both collagen and carbon nanotubes,it has most of the characteristics that an ideal biomaterial requires in order to be used as an osteoinductive *** biocomposite is bioresorbable and biodegradable and has the desired mechanical rigidity while maintaining a three-dimensional(3-D)nanostructured *** stability and swelling were achieved under fluid environments by varying the amount of carbon nanotubes(CNTs)incorporated into the *** variations can dictate the degree of interaction between fibroblastic cells and the ***-of-concept was shown by performing an in vitro induced mineralization of hydroxylapatite crystals under physiological ***,the ability to attach biofunctional groups to the CNT walls can open a new road for tissue regeneration since the combination of CNTs with specific growth factors or cellular ligands can create an environment capable of signaling and infl uencing specifi c cell *** observations suggest that collagen/carbon nanotube biocomposites will have important uses in a wide range of biotechnological areas.

关键词： Biomaterials carbon nanotubes collagen tissue engineering biocompatibility

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Calibrations of Amber Perspex-PMMA Dosimeter in the CDTN Gamma Irradiator operational Conditions

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Journal of Energy and Power Engineering 2015年第3期9卷 245-251页

作者： luiz Carlos Duarte ladeira Amir Zacarias Mesquita Marcio Tadeu Pereira Nuclear Technology Development Center--CDTN National Nuclear Energy Commission--CNEN Belo Horizonte 31270-901Brazil

This paper presents results of PMMA （polymethylmethacrylate） dosimeters calibrations that are used as routine dosimeters in CDTN （Nuclear Technology Development Center） Gamma Irradiation Laboratory. The study was carried out within the framework of the Facility Quality Assurance Program with the purpose of to determine the calibration curve and accuracy of the Harwell Amber Perspex 3042 W dosimeters. The irradiations of the dosimeters were made in operational conditions of a Gamma lrradiator at CDTN, an R ＆ D （research and development） institute connected to the CNEN （National Nuclear Energy Commission）（Brazil）. The values for estimate of the expanded uncertainties achieved are typical of a routine dosimetry system.

关键词： Accuracy PMMA dosimeter gamma processing absorbed dose irradiator.

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