pallid Swifts(Apus pallidus),as other swifts,are birds extremely adapted to an aerial lifestyle,showing unique adaptations that allow them to fly almost *** diet of these non-stopping high-altitudinal aerial birds has...
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pallid Swifts(Apus pallidus),as other swifts,are birds extremely adapted to an aerial lifestyle,showing unique adaptations that allow them to fly almost *** diet of these non-stopping high-altitudinal aerial birds has been mostly studied through techniques that fail to produce highly resolved prey identifications,and for that have been replaced by molecular techniques,such as DNA *** samples of pallid Swifts were monthly collected from a colony in the north of portugal during the breeding *** from the faecal samples was used to sex the birds and to identify the arthropods present in the diet through DNA *** the detected prey items,74 families were identified belonging to 16 orders,with Hymenoptera and Hemiptera being the most frequently *** were seasonal variations in diet richness,composition and prey *** the diet of males and females,although no differences were found between the diet of males and females in terms of composition and richness,there were differences in the size of arthropods preyed by the different sexes,with males feeding on larger *** large seasonal variation in pallid Swifts’diet during the breeding season is probably a result of spatiotemporal variation in aerial prey,of which swifts likely predate *** no significant differences were detected in diet richness and composition between sexes,the fact that males consumed larger prey may suggest the existence of sexual dietary segregation in this group of *** last,several pest species were found in these swifts’diet,which,if studied through DNA metabarcoding,can be used to monitor small arthropods,including airborne pests.
photobiomodulation,originally used red and near-infrared lasers,can alter cellular *** has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infrared light...
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photobiomodulation,originally used red and near-infrared lasers,can alter cellular *** has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infrared light promotes adipose stem cell proliferation and affects adipose stem cell migration,which is necessary for the cells homing to the site of *** this in vitro study,we explored the potential of adipose-derived stem cells to differentiate into neurons for future translational regenerative treatments in neurodegenerative disorders and brain *** investigated the effects of various biological and chemical inducers on trans-differentiation and evaluated the impact of photobiomodulation using 825 nm near-infrared and 525 nm green laser light at 5 J/*** adipose-derived stem cells can be used in autologous grafting and photobiomodulation has been shown to have biostimulatory *** findings reveal that adipose-derived stem cells can indeed trans-differentiate into neuronal cells when exposed to inducers,with pre-induced cells exhibiting higher rates of proliferation and trans-differentiation compared with the control ***,green laser light stimulation led to notable morphological changes indicative of enhanced trans-differentiation,while near-infrared photobiomodulation notably increased the expression of neuronal *** biochemical analysis and enzyme-linked immunosorbent assays,we observed marked improvements in viability,proliferation,membrane permeability,and mitochondrial membrane potential,as well as increased protein levels of neuron-specific enolase and ciliary neurotrophic ***,our results demonstrate the efficacy of photobiomodulation in enhancing the trans-differentiation ability of adipose-derived stem cells,offering promising prospects for their use in regenerative medicine for neurodegenerative disorders and brain injuries.
Neurodegenerative diseases are a major public health challenge,mainly affecting the elderly population and compromising their cognitive,sensory,and motor ***,available therapies focus on alleviating symptoms and slowi...
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Neurodegenerative diseases are a major public health challenge,mainly affecting the elderly population and compromising their cognitive,sensory,and motor ***,available therapies focus on alleviating symptoms and slowing the progression of these conditions,but they do not yet offer a definitive *** this scenario,terpenes emerge as promising natural alternatives due to their neuroprotective *** compounds can reduce the formation of protein aggregates,neutralize free radicals,and inhibit pro-inflammatory enzymes,which are crucial factors in the development of neurodegenerative *** addition,terpenes also play an important role in the regulation and remodeling of the extracellular matrix,a key target for improving neuronal *** such as linalool,pinene,and eugenol,among others,have potential therapeutic effects by modulating inflammatory and oxidative stress processes,the main factors that contribute to the progression of these *** suggest that these compounds act on signaling pathways that regulate the extracellular matrix,improving neuronal integrity and,consequently,cognitive and motor *** work aims to review the potential of terpenes in the treatment of neurodegenerative disorders,with emphasis on their ability to regulate oxidative stress and inflammation,as well as to remodel the extracellular *** interaction between these mechanisms points to the promising use of terpenes as an innovative and natural therapeutic approach to combat these diseases.
The video article by Teles and Wroclawski[1],titled“Membranous and prostatic urethra calcification due to Corynebacterium urealyticum infection,”presents a compelling case study of an 85-year-old patient who develop...
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The video article by Teles and Wroclawski[1],titled“Membranous and prostatic urethra calcification due to Corynebacterium urealyticum infection,”presents a compelling case study of an 85-year-old patient who developed significant calcifications in the membranous and prostatic urethra following a Corynebacterium urealyticum(***)*** video article is particularly valuable,as it includes relevant endoscopic images that vividly illustrate the calcifications and subsequent endoscopic treatment.
The manuscript by pereira et al.~([1])provides a detailed examination of the symptoms and satisfaction levels in patients using double-J ureteral *** study is significant as it addresses the common complications assoc...
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The manuscript by pereira et al.~([1])provides a detailed examination of the symptoms and satisfaction levels in patients using double-J ureteral *** study is significant as it addresses the common complications associated with ureteral stents,which are widely used in urological practice for managing upper urinary tract obstructions.
This paper proposes a fast coordinated power control method based on two augmented channels(AC)in battery energy storage system(BESS)to improve inertial and voltage support capability,i.e.,a frequency-reactive power c...
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This paper proposes a fast coordinated power control method based on two augmented channels(AC)in battery energy storage system(BESS)to improve inertial and voltage support capability,i.e.,a frequency-reactive power channel(FRpC)and a voltage-real power channel(VRpC).For frequency control in the power distribution system with high resistance/inductance ratio,the coupling mechanism between rate of change of frequency(RoCoF)and required reactive power(RRp)of grids is analyzed,indicating RoCoF is proportional to ***,RoCoF is utilized in FRpC to generate reactive power for complementary inertial emulating ***,for voltage control,coupling characteristics between rate of change of voltage(RoCoV)and demanding real power(DRp)of grids is also studied,revealing RoCoV is proportional to ***,it can be adopted in VRpC to generate real power for complementary voltage ***,grid-voltage-modulated direct power control is selected as the inner power control loop to track power references with faster dynamic performance compared with traditional vector-oriented ***,simulations and hardware-in-loop experiments validate improvement in performance of grid frequency and voltage control based on the proposed method.
The intricate interplay between natural compounds like curcumin and the gut microbiome has gained significant attention in recent years due to their potential therapeutic implications in various health ***,a polypheno...
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The intricate interplay between natural compounds like curcumin and the gut microbiome has gained significant attention in recent years due to their potential therapeutic implications in various health ***,a polyphenolic compound derived from turmeric,exhibits diverse pharmacological properties,including anti-inflammatory,antioxidant,and anticancer *** how curcumin modulates gut microbiota composition and function is crucial for elucidating its therapeutic *** review examines the current literature on the interactions between curcumin and the gut microbiome.A systematic search of relevant databases was conducted to identify studies investigating the effects of curcumin on gut microbial diversity and *** findings from studies exploring curcumin's efficacy in neurological disorders,gastrointestinal diseases,and metabolic dysfunction are synthesized and *** have demonstrated that curcumin supplementation can modulate gut microbiota composition and function,leading to beneficial effects on gut health and *** underlying curcumin's therapeutic effects include immune modulation,neuroprotection,and inflammation ***,challenges such as poor bioavailability and safety concerns remain significant hurdles to *** interactions between curcumin and the gut microbiome hold promise for therapeutic interventions in a diverse range of health *** research is needed to optimize curcumin formulations,improve bioavailability,and address safety concerns.
BACKGROUND Acute liver failure(ALF)is a severe condition characterized by rapid deterioration of liver function in individuals without preexisting liver *** transplantation(LT)is the most impactful *** fever(YF)is an ...
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BACKGROUND Acute liver failure(ALF)is a severe condition characterized by rapid deterioration of liver function in individuals without preexisting liver *** transplantation(LT)is the most impactful *** fever(YF)is an infectious disease that primarily affects the liver and has a high mortality ***,LT can be a viable option for treating rare cases with extensive liver ***,the criteria for assessing the severity of ALF and determining the indications for transplantation have not been specifically validated for cases caused by *** To present necessary adjustments to established scoring systems for ALF secondary to *** This was an observational,retrospective,single-center *** consecutive patients with confirmed ALF due to YF were monitored in the intensive care unit by a specialized liver transplant team during a three-month epidemic outbreak in *** hospitalization,general supportive therapeutic measures were implemented,and the patients were regularly assessed using the King's College criteria and the Clichy-Villejuif criteria to determine the severity of liver *** is considered a viable measure for patients with signs of end-stage liver *** Eight of 14(57%)patients developed severe neurological alterations within the first 96 hours after hospital *** patients underwent emergency LT,and despite a moderate viral infection of the graft after transplantation,the 5-year survival rate was 50%.Although the King's College criteria and the Clichy-Villejuif criteria are the main scoring systems for ALF,they are insufficient for predicting the risk of mortality in this context,primarily because of low serum bilirubin levels in the final stage of the disease and significant disparities between coagulation abnormalities and patient *** To ensure good applicability in cases of YF-induced ALF,the authors suggest adaptations to the King's College and Clichy-Vill
BACKGROUND Cirrhotic patients face heightened energy demands,leading to rapid glycogen depletion,protein degradation,oxidative stress,and inflammation,which drive disease progression and *** disruptions cause cellular...
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BACKGROUND Cirrhotic patients face heightened energy demands,leading to rapid glycogen depletion,protein degradation,oxidative stress,and inflammation,which drive disease progression and *** disruptions cause cellular damage and parenchymal changes,resulting in vascular alterations,portal hypertension,and liver dysfunction,significantly affecting patient *** To analyze the association between Child–Turcotte–pugh(CTp)scores and di-fferent nutritional indicators with survival in a 15-year follow-up *** This was a retrospective cohort study with 129 cirrhotic patients of both sexes aged>18 *** of cirrhosis was made by liver *** first year of data collection was 2007,and data regarding outcomes were collected in *** were gathered from medical records,and grouped by different methods,including CTp,handgrip strength,and triceps skinfold *** prognostic values for mortality were assessed using Kaplan–Meier curves and multivariate binary logistic regression *** The coefficient for CTp was the only statistically significant variable(Wald=5.193,p=0.023).This suggests that with a negative change in CTp classification score,the odds of survival decrease 52.6%.The other evaluated variables did not significantly predict survival outcomes in the ***–Meier survival curves also indicated that CTp classification was the only significant *** Although different classifications showed specific differences in stratification,only CTp showed significant predictive *** score remains a simple and effective predictive tool for cirrhotic patients even after longer follow-up.
Recent studies have shown a noticeable increase in global Helicobacter pylori(***)resistance,with clarithromycin resistance surpassing 15%in various ***,inadequate epidemiological monitoring,especially in developing c...
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Recent studies have shown a noticeable increase in global Helicobacter pylori(***)resistance,with clarithromycin resistance surpassing 15%in various ***,inadequate epidemiological monitoring,especially in developing countries,and the absence of uniform testing methods lead to discrepancies between regions and a possible underestimation of resistance *** complexity of treating *** is driven by its highly dynamic genome,which is prone to frequent mutations contributing to phenotypical *** usual course of action in empirical treatment involves using a combination of various drugs simultaneously,leading to significant resistance selection pressure and potential side *** emergence of *** strains resistant to multiple drugs is closely tied to failures in first-line treatment,highlighting the need to prevent further resistance by using optimal initial empirical therapy or regimens guided by antibiotic susceptibility testing,requiring a collection of mixed samples and multiple isolates for accurate *** emergence of new treatments like potassium-competitive acid blockers offers a hopeful approach to decrease antimicrobial usage while still ensuring effectiveness in comparison to traditional therapies with proton pump ***,the use of probiotics is under investigation to identify specific strains and formulations that may mitigate therapy-associated adverse effects.
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