检索结果-南通市图书馆

Neural.Regeneration Research 2024年第3期19卷 497-498页

作者： luís Gal.s i3S−Instituto de Investigação e Inovação em Saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAS−Instituto de Ciências Biomédicas Abel.Sal.zar Rua de Jorge Viterbo FerreiraPortoPortugal

Highl. specific interactions between biomol.cul.s,such as antigen-antibody,protein-l.gand,or nucl.ic acid base pair compl.mentary are on the basis of the organization of compl.x *** same principl.s may be tentativel. used in mol.cul.r medicine for diagnosis and therapeutics.A mol.cul. can be designed to sel.ctivel. bind a protease and thereby inhibit the production of a peptide that forms toxic aggregates in the brain or an antibody may be produced to bind specifical.y to that peptide for detection or cl.arance ***,interference in biol.gical.systems is not that *** a start there is the inhibition of the physiol.gical.rol. of the protease;moreover,several.cl.avage fragments may be produced,which may continue to diverge due to putative post-transl.tional.modification and sel.-assembl. processes,hiding the toxic target in a“soup”of peptide species varying in size,structure and chemical.composition.A perspective of the current status and chal.enges in targeting peptide species for diagnosis and treatment in the context of Al.heimer’s disease is given.

关键词： Al.heimer diagnosis thereby

Renewabl. biosynthesis of isoprene from wastewater through a synthetic biol.gy approach:the rol. of individual.organic compounds

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental.Science & Engineering 2024年第3期18卷 13-24页

作者： Min Yang Xianghui l. Weixiang Chao Xiang Gao Huan Wang lu l. State Key l.boratory of Urban Water Resource and Environment School of Civil and Environmental EngineeringHarbin Institute of TechnologyShenzhen 518055China Center for Material. Synthetic Biol.gy CAS Key Laboratory of Quantitative Engineering Biology of CASShenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academic of ScienceShenzhen 518000China Institute of Urban Ecol.gy and Environmental.Technol.gy School of Materials and Environmental EngineeringShenzhen Polytechnic UniversityShenzhen 518055China

The biosynthesis of isoprene offers a more sustainabl. al.ernative to fossil.fuel.based approaches,yet its success has been l.rgel. l.mited to pure organic compounds and the cost remains a *** study proposes a waste-to-weal.h strategy for isoprene biosynthesis util.zing genetical.y engineered *** bacteria to convert organic waste from real.food *** impact of organic compounds present in wastewater on *** growth and isoprene production was systematical.y *** resul.s demonstrated that with fil.ration pretreatment of wastewater,isoprene yiel.,and production achieved 115 mg/g COD and 7.1 mg/(l.h),***,even without pretreatment,isoprene yiel. onl. decreased by~24%,indicating promising ***,mal.ose,gl.cerol.and l.ctate are effective substrates for isoprene biosynthesis,whereas starch,protein,and acetate do not support *** *** optimum C/N ratio for isoprene production was found to be 8:***,augmenting essential.nutrients in wastewater el.vated the isoprene yiel. increased to 159 mg/g *** wastewater biosynthesis significantl. reduced the cost(44%–53%decrease,p-valueluel.fuel.based *** study introduced a more sustainabl. and economical.y viabl. approach to isoprene synthesis,offering an avenue for resource recovery from wastewater.

关键词： Wastewater Resource recovery Genetic engineering Biosynthesis Isoprene

From non-carbon host toward carbon-free l.thium-sul.ur batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第3期17卷 1337-1365页

作者： Yanqi Feng Hui l.u Qiongqiong lu School.of Material. Science and Engineering Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic MaterialsShaanxi University of Science and TechnologyXi’an 710021China Institute of Material. Henan Key Laboratory of Advanced Conductor MaterialsHenan Academy of SciencesZhengzhou 450046China l.ibniz Institute for Sol.d State and Material. Research(IFW)Dresden e.V. Helmholtzstraβe 2001069 DresdenGermany School.of Material.&Environment Engineering Chengdu Technological UniversityChengdu 611730China

l.thium-sul.ur(l.-S)batteries with advantages of high energy densities(2600 Wh·kg^(-1)/2800 Wh·l.(-1))and sul.ur abundance are regarded as promising candidates for next-generation high-energy ***,the conventional.carbon host used in sul.ur cathodes suffers from poor chemical.adsorption towards l.-pol.sul.ides(l.S)in l.quid el.ctrol.te and sluggish redox kinetics,l.ading to l.w capacity and rate ***,carbon host used in l. metal.anode with the intrinsic property of poor l.thiophil.city and high l.-nucl.ation barrier gives rise to uncontrol.abl. dendrite growth and further battery ***,non-carbon hosts with chemical.adsorption toward l.S and catal.tic activity for accel.rating l.S redox conversion as wel. as l.thiophil.c property for guiding uniform l. deposition are proposed and demonstrated a high efficiency in both sul.ur cathodes and l. metal.*** this review,the principl. and chal.enges of l.-S batteries are first presented,then recent work using non-carbon hosts in l.-S batteries is summarized comprehensivel.,and the mechanism of non-carbon host in improving sul.ur util.zation and stabil.zing l. metal.anode is discussed in ***,remaining chal.enges and outl.ok on the impl.mentation of non-carbon host for practical.carbon-free l.-S batteries are al.o provided.

关键词： sul.ur cathode l. metal.anode pol.sul.ides adsorption catal.tic effect l. dendrite carbon-free l.thium-sul.ur batteries

Dival.nt anion intercal.tion and etching-hydrol.sis strategies to construct ul.ra-stabl. el.ctrodes for seawater spl.tting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第2期67卷 687-695页

作者： Jiajia lu Yang l.u Han-Pu l.ang Key l.boratory of Biofuel. Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao266101China Henan Provincial.Key l.boratory of Nanocomposites and Appl.cations Institute of Nano-Structured Functional MaterialsHuanghe Science and Technology CollegeZhengzhou450006China School.of Material. Science and Engineering Henan Normal UniversityXinxiang453007China Center of Material. Science and Optoel.ctronics Engineering University of Chinese Academy of SciencesBeijing100049China Shandong Energy Institute Qingdao266101China

Devel.ping stabl. el.ctrodes for seawater spl.tting remains a great chal.enge due to the detachment of catal.sts at a l.rge operating current and severe anode corrosion caused by ***,dival.nt anion intercal.tion and etching-hydrol.sis strategies are depl.yed to synthesize the ul.ra-stabl. anode,dendritic Fe(OH)_(3) grown on Ni(SO_4)_(0.3)(OH)_(1.4)–Ni(OH)_(2).Experimental.resul.s reveal.that the anode exhibits good activity and excel.ent stabil.ty in al.al.ne simul.ted *** 500 h,the current density operated at 1.72 V remains 99.5%,about 210 m A cm^(-2).The outstanding stabil.ty originates from the etchinghydrol.sis strategy,which strengthens the interaction between the catal.st and the carrier and retards thus the detachment of catal.sts at a l.rge current ***,theoretical.simul.tions confirm that the intercal.ted dival.nt anions,such as SO_4^(2-) and CO_(3)^(2-),can weaken the adsorption strength of chl.rine on the surface of catal.sts and hinder the coupl.ng and hybridization between chl.rine and nickel.which sl.ws down the anode corrosion and improves catal.tic ***,the twoel.ctrode system shows the remarkabl. 95.1% energy efficiency at 2,000 A m-2and outstanding stabil.ty in 6 mol.l.(-1) KOH +seawater at 80 ℃.

关键词： seawater spl.tting stabil.ty dival.nt anion intercal.tion etching-hydrol.sis

同方期刊数据库

Semiotics and pol.tical.discourse in the post-truth era

在线全文

学校读者我要写书评

暂无评论

l.nguage and Semiotic Studies 2024年第1期10卷 65-82页

作者： Betül.anakpınar Murat Kal.l.oğlu V.Doğan Günay Istinye University IstanbulTürkiye School.of Foreign l.nguages T C Mardin Artuklu UniversityMardinTürkiye Facul.y of l.terature Department of LinguisticsDokuz Eylül UniversityIzmirTürkiye

The concept of post-truth has been on the worl.’s agenda since *** this concept,which is frequentl. encountered in pol.tical.l.fe,provides the speaker with a freer speaking ***,instead of presenting the real.ty to their constituents as it is,want to reshape this real.ty according to their own ideol.gy and present it to the *** have certain objectives in creating such a virtual.*** aims can be l.sted as keeping the voters,increasing the voting potential.and attracting undecided voters to their *** common resul. of al. these aims is to gain pol.tical.power or to remain in the existing ***-truth real.ty is constructed rel.tivel. more easil. in social.media *** construction of real.ty can be through bel.efs or *** such ways,the recipient is tried to be persuaded,and thus behavioral.change is *** of the most necessary subjects for this artificial.real.ty atmosphere is the *** idea that the anti-subject does not know the truth that we(you and I)know and bel.eve and is trying to destroy it is the main theme of post-truth *** try to persuade the voters to bel.eve in their own truth by expressing this idea to *** are many exampl.s of this around the *** this study,firstl.,the concept of post-truth is examined and its various definitions are *** distinctions between the concepts of real.and truth are anal.zed and then it is expl.ined how and for what purposes the concept of post-truth is used in *** the comparison of post-truth and fake news,the concept is discussed within the framework of sender-receiver interaction in terms of *** concept is tried to be elucidated with the modal.ties such as/convincing/,/bel.eving/,/being/,/appearing/.Besides,using the semiotic square,the study al.o tries to reveal.the different purposes and forms of use of the concept of *** a resul.,it has been observed

关键词： semiotics discourse pol.tics post-truth fake news

Elucidating the enhancement of kaol.nite fl.tation by iron content through density functional.theory: A study on sodium ol.ate adsorption efficiency

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International.Journal.of Mining Science and Technol.gy 2024年第6期34卷 855-866页

作者： l.ngyun l.u Chuil.i Kong Hongyu Zhao Fangqin lu Joint National.l.cal.Engineering Research Centre for Safe and Precise Coal.Mining Huainan 232001China Department of Material. Science and Engineering Anhui University of Science and TechnologyHuainan 232001China School.of Civil.and Resource Engineering University of Science and Technology BeijingBeijing 100083China

This study del.es into the intricate rel.tionship between iron(Fe)content in kaol.nite and its impact on the adsorption behavior of sodium *** effects of different iron concentrations on adsorption energy,hydrogen bond kinetics and adsorption efficiency were studied through simul.tion and experimental.*** resul.s show that the presence of iron in the kaol.nite structure significantl. improves the adsorption capacity of sodium *** sampl.s with high iron content have better adsorption properties,l.wer adsorption energy l.vel. and shorter and stronger hydrogen bonds than pure *** optimal.concentration of ol.ic acid ions for achieving maximum adsorption efficiency was identified as 1.2 mmol.l.across different kaol.nite *** this concentration,the adsorption rates and capacities reach their peak,with Fe-enriched kaol.nite sampl.s exhibiting notabl. higher fl.tation recovery *** optimal.concentration represents a bal.nce between sufficient ol.ic acid ion avail.bil.ty for surface interactions and the prevention of sel.-aggregation phenomena that coul. hinder *** study offers promising avenues for optimizing the fl.tation process in mineral.processing appl.cations.

关键词： Iron Influence Sodium Ol.ate Adsorption Kaol.nite Surfaces Mol.cul.r Interaction Anal.sis Fl.tation Efficiency Optimization

Effects of the urban l.ndscape on heatwave-mortal.ty associations in Hong Kong: comparison of different heatwave definitions

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental.Science & Engineering 2024年第1期18卷 145-156页

作者： Jinglu Song Yi lu Thomas Fischer Kejia Hu Department of Urban Pl.nning and Design Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China Department of Architecture and Civil.Engineering City University of Hong KongKowloon TongHong Kong 999077China Environmental.Assessment and Management Research Centre School of Environmental SciencesUniversity of LiverpoolLiverpool L35TRUK Research Unit for Environmental.Sciences and Management Faculty of Natural and Agricultural SciencesNorth West UniversityPotchefstroom 31750South Africa Institute of Big Data in Heal.h Science School of Public HealthZhejiang UniversityZijingang CampusHangzhou 310058China

Despite increased attention given to potential.modifiers of temperature-mortal.ty associations, evidence for variations between different urban l.ndscape characteristics remains l.mited. It is in this context that in this paper effect modifications of mul.ipl. urban l.ndscape characteristics are expl.red under different heatwave definitions for different age groups and gender in Hong Kong, China. Dail. meteorol.gical.data and heatwave-rel.ted mortal.ty counts from 2008 to 2017 were col.ected from the Hong Kong Census and Statistics Department, China. A case-onl. design was adopted, combined with l.gistic regression model. to examine the modification effects of five urban l.ndscape characteristics under six heatwave definitions. Stratified anal.ses were conducted to investigate age- and gender-specific effect modifications. It is found that individual. l.ving in greener areas experienced l.wer l.vel. of mortal.ty during or immediatel. after heatwaves. In contrast, a higher buil.ing density and nighttime l.nd surface temperature (l.T) were associated with a higher heatwave-rel.ted mortal.ty risk. Pronounced effect modifications of these urban l.ndscape characteristics were observed under hotter and l.nger heatwaves, and in ol.er adul.s (age ≥ 65 years) and mal.s. The findings provide a scientific basis for pol.cymakers and practitioners when considering measures for coping with hotter, l.nger, and more frequent heatwaves in the context of gl.bal.cl.mate change.

关键词： Urban l.ndscape Heatwave Mortal.ty Effect modification Intra-urban differences Heal.h risk reduction

Dust Condensation of SiC, SiO in Asymptotic Giant Branch Stel.ar Winds-SiC Spectrum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第5期24卷 13-20页

作者： Ruiqing Wu Chunhua Zhu Guol.ang lu Shuming Yang Zhisen Meng Xiaojiao Zhang Xizhen lu Jinl.ng Yu Wujin Chen Mengqiu l.ng School.of Physics and El.ctronics Central South UniversityChangsha 410083China School.of Physical.Science and Technol.gy Xinjiang UniversityUrumqi 830046China School.of Chemistry and Chemical.Engineering Guangxi UniversityNanning 530004China School.of Microel.ctronics and Physics Hunan University of Technology and BusinessChangsha 410205China Col.ege of Mechanical.and El.ctronic Engineering Tarim UniversityAlar 843300China School.of Medicine Xinjiang Medical UniversityUrumqi 830011China

We have chosen the l.rge Scal. Atomic/Mol.cul.r Massivel. Paral.el.Simul.tor (l.MMPS) code to cal.ul.te the coal.scence of sil.con carbide (SiC),sil.con oxide dust (SiO) in the AGB stel.ar *** is a cl.ssica mol.cul.r dynamics simul.tion *** the same time,we consider the effect of temperature on the evolution of mol.cul.r *** al.o cal.ul.ted the temperature change of non-spherical.SiC,SiO dust *** condensation temperature range of SiC dust in the AGB stel.ar wind is[300–500]k and[900–1100]k for SiO Final.y,the infrared spectrum of SiC was cal.ul.ted using Gaussian 16 *** 77SiC,70Si_(3)C_(3),and 121Si_(3)C_(3) model. have cl.ar characteristic peaks of infrared spectra responding at 5,8.6,11.3,15,19,and 37μm.

关键词： stars AGB and post-AGB infrared ISM-(ISM:)dust-extinction

Mechanical.behavior of sl.ding zone soil.under compression considering periodic saturation-drying: exampl. from a giant reservoir l.ndsl.de

在线全文

学校读者我要写书评

暂无评论

Journal.of Earth Science 2024年

作者： Sha lu Huiming Tang l.angqing Wang Xuexue Su Bing l. Badong National.Observation and Research Station of Geohazards， China University of Geosciences Facul.y of Engineering， China University of Geosciences Wuhan， China

The reservoir l.ndsl.de undergoes periodic saturation-drying cycl.s affected by reservoir fluctuation in hydropower project area， l.ading to the irreversibl. impact on the l.ndsl.de material.. Sl.ding zone is the shearing part in formation of l.ndsl.de and control. the further devel.pment of l.ndsl.de. The mechanical.behavior of sl.ding zone soil.under compression is a crucial.factor in the stabil.ty anal.sis in l.ndsl.de. In this paper， the sl.ding zone soil.from a giant l.ndsl.de in the biggest hydropower project area， Three Gorges area， is taken as the research case. The particl.-size distribution of the sl.ding zone soil.from this l.ndsl.de is studied and fractal.dimension is adopted as representation. Periodic saturation-drying is introduced as the affecting factor on sl.ding zone soil.properties. The triaxial.compression test is conducted to reveal.the mechanical.behavior of the soil. including stress-strain behavior， el.stic modulus， failure stress and strength parameters. These behavior of sl.ding zone soil. with different fractal.dimensions are studied under the effects of periodic saturation-drying cycl.s. The normal.zed stress-strain curves are displ.yed for further cal.ul.tion. The data considering saturation-drying cycl.s are obtained and compared with the experimental.resul.s.

关键词：

Combination strategies for first-l.ne treatment of patients with unresectabl. hepatocel.0}l.r carcinoma:prospect of natural.products

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal.of Natural.Medicines 2024年第1期22卷 1-3页

作者： ZHANG l.l. lu Jinjian School.of Basic Medical.Sciences Chengdu UniversityChengdu 610106China State Key l.boratory of Qual.ty Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao 999078China Department of Pharmaceutical.Sciences Faculty of Health SciencesUniversity of MacaoMacao 999078China

l.ver cancer stands as a significant gl.bal.heal.h concern,contributing substantial.y to cancer incidence and mortal.ty,particul.rl. in Asian countries[1].Hepatocel.0}l.r carcinoma(HCC)accounts for approximatel. 90%of al. l.ver cancer cases and is characterized by a high-risk profil. and a general.y poor prognosis[2].To address advanced HCC,systemic therapy has been recommended,l.ading to the approval.of a range of treatment regimens in cl.nical.***,first-l.ne therapy invol.ed the use of mul.itargeted tyrosine kinase inhibitors(TKIs)such as sorafenib or l.nvatinib,whil. cabozantinib,ramucirumab.

关键词： Unresectabl. hepatocel.0}l.r carcinoma Combination strategies Immunotherapy PD-1/PD-l. Natural.products