检索结果-南通市图书馆

An ethically guided preclinical device for phenotyping H_(2)production in laboratory rodents

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2024年第4期7卷 553-561页

作者： Victor Pascal-Moussellard Emilie Boucher stéphane Tanguy Philippe Cinquin pierre-Alain Barraud ChloéDavin Cordélia Salomez-Ihl Dalil Hannani François Boucher Jean-pierre Alcaraz University Grenoble Alpes CNRSUMR 5525VetAgro SupGrenoble INPTIMCGrenobleFrance

Background:Dihydrogen(H_(2))is produced endogenously by the intestinal microbiota through the fermentation of diet *** the past few years,numer-ous studies have demonstrated the significant therapeutic potential of H_(2)in various pathophysiological contexts,making the characterization of its production in labora-tory species of major preclinical ***:This study proposes an innovative solution to accurately monitor H_(2)pro-duction in free-moving rodents while respecting animal welfare *** devel-oped device consisted of a wire rodent cage placed inside an airtight chamber in which the air quality was maintained,and the H_(2)concentration was continuously *** the airtightness and efficiency of the systems used to control and maintain air quality in the chamber were checked,tests were carried out on rats and mice with different metabolic phenotypes,over 12 min to 1-h experiments and repeatedly.H_(2)production rates(HPR)were obtained using an easy calculation algorithm based on a first-order moving ***:HPR in hyperphagic Zucker rats was found to be twice as high as in control Wistar rats,respectively,2.64 and 1.27 nmol.s^(−1)per *** addition,the ingestion of inulin,a dietary fiber,stimulated H_(2)production in *** were 0.46 nmol.s^(−1)for animals under control diet and 1.99 nmol.s^(−1)for animals under inulin ***:The proposed device coupled with our algorithm enables fine analysis of the metabolic phenotype of laboratory rats or mice with regard to their endogenous H_(2)production.

关键词： hydrogen therapy laboratory rodents microbiota molecular hydrogen noninvasive monitoring device

What If the Protection against Oxidation of Chromia-Forming Alloys Was Not Always Due to the Chromia Layer?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Analytical Chemistry 2024年第9期15卷 286-302页

作者： Boris Contri stéphane Valette Marina Soustre pierre Lefort IRCER European Ceramics Centre UMR CNRS 7315 University of Limoges 12 rue Atlantis Limoges Cedex France

Chromia-forming alloys have good resistance to oxidizing agents such as O2, CO2, … It is accepted that the protection of these alloys is always due to the chromia layer formed at the surface of the alloys, which acts as a barrier between the oxidizing gases and the alloy substrates, forming a diffusion zone that limits the overall reaction rate and leads to parabolic kinetics. But this was not verified in the study devoted to Inconel®625 the oxidation in CO2 that was followed by TGA, with characterizations by XRD, EDS and FIB microscopy. Contrary to what was expected and accepted in similar studies on other chromia-forming alloys, it was shown that the diffusion step that governs the overall reaction rate is not located inside the chromia layer but inside the alloy, precisely inside a zone just beneath the interface alloy/chromia, this zone being depleted in chromium. The chromia layer, therefore, plays no kinetic role and does not directly protect the underlying alloy. This result was demonstrated using a simple test that consisted in removing the chromia layer from the surface of samples partially oxidized and then to continue the thermal treatment: insofar as the kinetics continued without any change in rate, this proved that this surface layer of oxide did not protect the substrate. Based on previous work on many chromia-forming alloys, the possibility of a similar reaction mechanism is discussed. If the chromia layer is not the source of protection for a number of chromia-forming alloys, as is suspected, this might have major consequences in terms of industrial applications.

关键词： Chromia-Forming Alloys Chromia Layer Oxidation Protection Inconel®625 Kinetics

A spotlight on dosage and subject selection for effective neuroprotection: exploring the central role of mitochondria

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1081-1082页

作者： John Mitrofanis Jonathan stone Michael R.Hamblin pierre Magistretti Alim-louis Benabid Glen Jeffery Fonds Clinatec UniversitéGrenoble AlpesGrenobleFrance School of Medical Science University of SydneySydneyAustralia Faculty of Health Sciences University of JohannesburgJohannesburgSouth Africa King Abdullah University of Science and Technology ThuwalSaudi Arabia Institute of Ophthalmology University College LondonLondonUK

Neurons are notoriously vulnerable cell *** the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological conditions,including stroke,head trauma,and neurodegenerative disease,can generate stress in neurons,affecting their survival and proper *** most neural pathologies,mitochondria become dysfunctional and this plays a pivotal role in the process of cell *** challenge over the last few decades has been to develop effective interventions that improve neuronal homeostasis under pathological *** interventions,often referred to as disease-modifying or neuroprotective,have,however,proved frustratingly elusive,at both preclinical and,in particular,clinical *** this perspective,we highlight two factors that we feel are key to the development of effective neuroprotective *** are:firstly,the choice of dose of intervention and method of application,and secondly,the selection of subjects,whether they be patients or the animal model.

关键词： protective dosage distress

Seasonal Dynamic of the Fall Armyworm, Spodoptera frugiperda (J.E Smith, 1797) (Lepidoptera: Noctuidae) on Maize Crop in the Sub-Sudanese Zone of Côte d’Ivoire

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in Entomology 2024年第2期12卷 78-92页

作者： stéphanie Manuela Klamansoni Akissi Konan Laya Kansaye Nondenot Roi louis Aboua West Africa Science Service Centre on Climate Change and Land Used (WASCAL) Abidjan C&#244te d&#8217Ivoire Rural Polytechnic Institute of Training and Applied Research Katibougou Mali Department of Entomology and Ecosystem Management F&#233lix Houphou&#235t-Boigny University Abidjan C&#244te d&#8217Ivoire

In Côte d’Ivoire, maize (Zea mays L) is the second most cultivated cereal after rice. Since the first report of Spodoptera frugiperda in Côte d’Ivoire, maize production in the northern regions has been affected resulting in maize production losses. This study aims to study the seasonal dynamic of Spodoptera frugiperda in maize fields in the sub-Sudanese zone, main zone of maize cultivation in Côte d’Ivoire. The study was done using pheromone trap lures. The results revealed a variation in the moth population at various growth stages during rainy and dry seasons. Notably, the highest numbers of moths were consistently trapped during the whorl stage with counts ranging from 131 ± 35.7 during the rainy season to 70.6 ± 15.01 in the dry season. The lowest numbers of moths were observed during pod maturation, with counts ranging from 30.3 ± 13.05 during the rainy season to 11.7 ± 3.05 in the dry season. Between the 7th and 21st days after sowing, the count of moths displayed a consistent upward trajectory, reaching 188 moths during the rainy season. The damages were particularly observed at whorl stage. The relationship between the numbers of moths and some climatic variables revealed a negative correlation between moths numbers and rainfall (r= −0.44) and relative humidity (r= −0.684). In contrast, there were positive relationships with temperature (r = 0.16), highlighting the significant impact of temperature changes on moth population dynamics. The research highlights the need for integrated pest management strategies that consider climatic factors and growth stages of maize to mitigate the impact of this insect pest on maize.

关键词： Spodoptera frugiperda Moths Climatic Variables Zea mays

Nearest Neighbor Sampling of Point Sets Using Rays

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications on Applied Mathematics and Computation 2024年第2期6卷 1131-1174页

作者： Liangchen Liu louis Ly Colin B.Macdonald Richard Tsai Department of Mathematics The University of Texas at Austin2515 SpeedwayAustinTX 78712USA Oden Institute for Computational Engineering and Sciences The University of Texas at Austin201 E24th StAustinTX 78712USA Department of Mathematics University of British Columbia1984 Mathematics RdVancouverBCV6T1Z2Canada

We propose a new framework for the sampling,compression,and analysis of distributions of point sets and other geometric objects embedded in Euclidean *** approach involves constructing a tensor called the RaySense sketch,which captures nearest neighbors from the underlying geometry of points along a set of *** explore various operations that can be performed on the RaySense sketch,leading to different properties and potential *** information about the data set can be extracted from the sketch,independent of the ray *** integrals on point sets can be efficiently computed using the *** also present several examples illustrating applications of the proposed strategy in practical scenarios.

关键词： Point clouds Sampling Classification Registration Deep learning Voronoi cell analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

极端天气增多露天音乐会应加强应急预案

商业周刊（中文版） 2024年第10期 28-31页

作者： Kendra pierre-louis 逸思(译) 不详

户外活动面临的极端天气威胁逐年增加,高温、暴风雨、野火烟雾、龙卷风都有可能导致人员伤亡。安娜·克拉拉·贝内维德斯(Ana Clara Benevides)在失去意识前,很可能是感到了呼吸困难。2023年11月17日,泰勒·斯威夫特(Taylor Swift)在里... 详细信息

户外活动面临的极端天气威胁逐年增加,高温、暴风雨、野火烟雾、龙卷风都有可能导致人员伤亡。安娜·克拉拉·贝内维德斯(Ana Clara Benevides)在失去意识前,很可能是感到了呼吸困难。2023年11月17日,泰勒·斯威夫特(Taylor Swift)在里约热内卢尼尔顿桑托斯体育场举行演唱会,现场观众人数达到6万名,热浪袭人,“体感温度”高达59摄氏度。

关键词：斯威夫特极端天气体感温度克拉拉呼吸困难桑托斯龙卷风暴风雨

Alexa,let's train now!——A systematic review and classification approach to digital and home-based physical training interventions aiming to support healthy cognitive aging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第1期13卷 30-46页

作者： Fabian Herold Paula Theobald Thomas Gronwald Navin Kaushal Liye Zou Eling D.de Bruin louis Bherer Notger GMüller Research Group Degenerative and Chronic Diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam 14476Germany Body-Brain-Mind Laboratory Shenzhen UniversityShenzhen 518060China Institute of Interdisciplinary Exercise Science and Sports Medicine MSH Medical School HamburgHamburg 20457Germany Department of Health Sciences School of Health&Human SciencesIndiana UniversityIndianapolisIN 46202USA Department of Health Sciences and Technology Institute of Human Movement Sciences and SportETH ZurichZurich 8093Switzerland Department of Neurobiology Care Sciencesand SocietyKarolinska InstituteStockholm 17177Sweden Department of Health OST-Eastern Swiss University of Applied SciencesSt.Gallen 9001Switzerland Montreal Heart Institute MontrealQC H1T 1C8Canada Department of Medicine Universite de MontrealMontrealQC H3T 1J4Canada Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal MontrealQC H3W 1W5Canada

Background:There is mounting evidence that regular physical activity is an important prerequisite for healthy cognitive ***,the finding that almost one-third of the adult population does not reach the recommended level of regular physical activity calls for further public health *** this context,digital and home-based physical training interventions might be a promising alternative to center-based intervention ***,this systematic review aimed to summarize the current state of the literature on the effects of digital and home-based physical training interventions on adult cognitive ***:In this pre-registered systematic review(PROSPERO;ID:CRD42022320031),5 electronic databases(PubMed,Web of Science,Psyclnfo,SPORTDiscus,and Cochrane Library)were searched by 2 independent researchers(FH and PT)to identify eligible studies investigating the effects of digital and home-based physical training interventions on cognitive performance in *** systematic literature search yielded 8258 records(extra17 records from other sources),of which 27 controlled trials were considered *** reviewers(FH and PT)independently extracted data and assessed the risk of bias using a modified version of the Tool for the assEssment of study qualiTy and reporting in EXercise(TEstEX scale).Results:Of the 27 reviewed studies,15 reported positive effects on cognitive and motor-cognitive outcomes(i.e.,performance improvements in measures of executive functions,working memory,and choice stepping reaction test),and a considerable heterogeneity concerning study-related,population-related,and intervention-related characteristics was noticed.A more detailed analysis suggests that,in particular,interventions using online classes and technology-based exercise devices(i.e.,step-based exergames)can improve cognitive performance in healthy older *** one-half of the reviewed studies were rated as having a high risk of bias with respect

关键词： Brain Cognition Digital health Exercise-cognition Physical activity

Liver surface depressions in the presence of diaphragmatic muscular bands on trans-illumination

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Experimental Medicine 2024年第2期14卷 5-10页

作者： Shamir O Cawich Michael T Gardner Ramanand Shetty Jean pierre Louboutin Zenica Dabichan Shaneeta Johnson Department of Surgery University of the West IndiesSt AugustineTrinidad and Tobago Section of Anatomy Department of Basic Medical SciencesUniversity of the West IndiesKingston KIN7Jamaica Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States

Traditional descriptions of liver anatomy refer to a smooth,convex surface contacting the *** depressions are recognized anatomic *** are many theories to explain the cause of the *** discuss the theory that these are... 详细信息

关键词： Liver Anatomy Depressions Fissure Groove Sulcus Variant

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

奥运选手借助科技手段迎战极端高温

商业周刊（中文版） 2024年第12期 30-34页

作者： Ira Boudway Kendra pierre-louis Hayley Warren Jin Wu 程玺(译) 孟洁冰(译) 不详

从穿戴式热传感器到充气式冰块池,奥运选手们各显神通,调整训练和比赛方式,以迎战极端高温对于代表美国队参加巴黎奥运会的精英山地自行车运动员克里斯托弗·布莱文斯(Christopher Blevins)来说,不适是比赛的常态。“当你在一个半小时... 详细信息

从穿戴式热传感器到充气式冰块池,奥运选手们各显神通,调整训练和比赛方式,以迎战极端高温对于代表美国队参加巴黎奥运会的精英山地自行车运动员克里斯托弗·布莱文斯(Christopher Blevins)来说,不适是比赛的常态。“当你在一个半小时内拼尽了全力,感觉良好是不可能的,”布莱文斯说,他也参加了上届东京夏季奥运会。

关键词：奥运选手夏季奥运会美国队极端高温克里斯托弗充气式训练和比赛山地自行车运动