检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

迟发的特发性震颤与痴呆相关

世界核心医学期刊文摘(神经病学分册) 2006年第11期 57-57页

作者： Benito-Leóon J louis e.d Bermejo-Pareja F 郭俊 Avda. C. 73 portal 3 7 Izquierda E-28820 Coslada Madrid Spain Dr.

OBJeCTIVe: To determine whether essential tremor (eT) is associated with prevalent dementia. MeTHOdS: The authors identified all persons with dementia and eT in a population-based study in central Spain (the Neurological disorders in Central Spain [NedICeS] Study). dementia was diagnosed using the.diagnostic and Statistical Manual of Mental disorders (4th ed.) criteria. ReSULTS: Thirty-one (11.4%) of 273 eT cases had dementia vs 204 (6.0%) of 3,382 non-eT subjects (controls) (odds ratio [OR] = 2.00, 95%CI = 1.34 to 2.98, p = 0.001). In a model that adjusted for age, stroke, and educational level, OR = 1.35, 95%CI = 0.87 to 2.18, and p = 0.17. In an adjusted model, eT cases with tremor onset after age 65 were 70%more likely to be.demented than were controls (OR = 1.70, 95%CI = 1.04 to 2.76, p = 0.03), whereas eT cases with tremor onset at age ≤65 and controls were equally likely to be.demented (OR = 0.38, 95%CI = 0.09 to 1.73, p = 0.21). CONCLUSIONS: Older-onset essential tremor (eT) was associated with dementia. Prospective studies are required to elucidate the association between eT and dementia.

关键词：特发性震颤迟发 eT

The 2024 Compe.dium of Physical Activities and its expansion

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第1期13卷 1-2,F0003页

作者： Stephen d.Herrmann erik A.Willis Barbara e.Ainsworth Kansas Center for Metabolism and Obesity Research University of Kansas Medical CenterKansas CityKS 66160USA Center for Health Promotion and disease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA School of exercise and Health Shanghai University of SportShanghai 200438China

First developed 30 years ago,the Compe.dium of Physical Activities(Compe.dium)was created to provide a standardized way of measuring and classifying specific physical activities(PAs),allowing researchers and health professionals to assess the energy expe.diture and health benefits associated with different PA.1Since its inception,the Compe.dium has been widely utilized and recognized as a fundamental PA and health resource.

关键词： has utilized classify

维普期刊数据库

2024 Wheelchair Compe.dium of Physical Activities:An update of activity codes and energy expe.diture values

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第1期13卷 18-23页

作者： Scott A.Conger Stephen d.Herrmann erik A.Willis Tom e.Nightingale Joseph R.Sherman Barbara e.Ainsworth department of Kinesiology Boise State UniversityBoiseID 83725USA Kansas Center for Metabolism and Obesity Research The University of Kansas Medical CenterKansas CityKS 66160USA Center for Health Promotion and disease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA School of Sport Exercise and Rehabilitation SciencesUniversity of BirminghamBirmingham AL B152TTUK Centre for Trauma Sciences Research University of BirminghamEdgbastonBirmingham AL B152TTUK College of Health Solutions Arizona State UniversityPhoenixAZ 85003USA School of exercise and Health Shanghai University of SportShanghai 200438China

Purpose:This paper presents an update of the 2011 Wheelchair Compe.dium of Physical Activities designed for wheelchair users and is referred to as the 2024 Wheelchair *** Wheelchair Compe.dium aims to curate existing knowledge of the energy expe.diture for wheelchair physical activities(PAs).Methods:A systematic review of the published energy expe.diture of PA for wheelchair users was completed between 2011 and May *** added these.data to the 2011 Wheelchair Compe.dium data that was compiled previously in a systematic review through ***:A total of 47 studies were included,and 124 different wheelchair PA reported energy expe.diture values ranging from 0.8 metabolic equivalents for wheelchair users(filing papers,light effort)to 11.8 metabolic equivalents for wheelchair users(Nordic sit skiing).Conclusion:In introducing the updated 2024 Wheelchair Compe.dium,we hope to bridge the resource gap and challenge the prevailing narratives that inadvertently exclude wheelchair users from physical fitness and health PAs.

关键词： disability exercise MeT Mobility

维普期刊数据库

Understanding the spectrum of non-motor symptoms in multiple sclerosis:insights from animal models

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第1期19卷 84-91页

作者： Poornima d.e.Weerasinghe-Mudiyanselage Joong-Sun Kim Taekyun Shin Changjong Moon department of Veterinary Anatomy and Animal Behavior College of Veterinary Medicine and BK21 FOUR programChonnam National UniversityGwangjuRepublic of Korea department of Veterinary Anatomy College of Veterinary Medicine and Veterinary Medical Research InstituteJeju National UniversityJejuRepublic of Korea

Multiple sclerosis is a chronic autoimmune.disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological *** addition to experiencing motor disability,patients with multiple sclerosis also experience a variety of nonmotor symptoms,including cognitive.deficits,anxiety,depression,sensory impairments,and ***,the pathogenesis and treatment of such non-motor symptoms in multiple scle rosis are still under *** studies for multiple sclerosis benefit from the use of disease-appropriate animal models,including experimental autoimmune *** to understanding the pathophysiology and developing treatments for non-motor symptoms,it is critical to chara cterize the animal model in terms of its ability to replicate certain non-motor features of multiple *** such,no single animal model can mimic the entire spectrum of *** review focuses on the non-motor symptoms that have been investigated in animal models of multiple sclerosis as well as possible underlying ***,we highlighted gaps in the literature to explain the nonmotor aspects of multiple sclerosis in expe rimental animal models,which will serve as the basis for future studies.

关键词： anxiety cognitive.deficit depression experimental autoimmune encephalomyelitis motor disability neurological disorder pain pathophysiology preclinical study sensory impairments

维普期刊数据库

Facile synthesis of intra-nanogap enhanced Raman tags with different shapes

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第9期17卷 8415-8423页

作者： Sanjun Fan Brian T.Scarpitti Zhewen Luo Abigail e.Smith Jian Ye Zachary d.Schultz department of Chemistry and Biochemistry The Ohio State UniversityColumbusOhio 43210USA School of Biomedical engineering Shanghai Jiao Tong UniversityShanghai 200030China

Hot spot engineering in plasmonic nanostructures plays a significant role in surface-enhanced Raman scattering(SeRS)for bioanalysis and cell ***,creating stable,reproducible,and strong SeRS signals remains challenging due to the potential interference from surrounding chemicals and locating SeRS-active analytes into hot-spot ***,we.developed a straightforward approach to synthesize intra-gap nanoparticles encapsulating 4-nitrobenzenethiol(4-NBT)as a reporter molecule within these gaps to avoid outside *** made three kinds of intra-gap nanoparticles using nanorods,bipyramids,and nanospheres as cores,in which the nanorods based intra-gap nanoparticles exhibit the highest SeRS *** advantage of our method is the ease of preparation of high-yie.d and stable intra-gap nanoparticles characterized by a short incubation time(10 min)with 4-NBT and quick synthesis without requiring an additional step to centrifuge for the purification of core *** intense localized fie.d in the synthesized hot spots of these plasmonic gap nanostructures holds great promise as a SeRS substrate for a broad range of quantitative optical applications.

关键词： hot spot engineering surface enhanced Raman scattering intra-gap nanoparticles 4-nitrobenzenethiol

Advanced strategies for marine antifouling based on nanomaterial-enhanced functional PdMS coatings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Materials Science 2024年第4期6卷 375-395页

作者： Xiaohui Shi Hao Wei Wenjun Zhou Paul e.d.Soto Rodriguez Cunguo Lin Lei Wang Zhijia Zhang School of Materials Science and Chemical engineering Harbin Engineering University Qingdao Innovation and development Center of Harbin engineering University State Key Laboratory for Marin Corrosion and Protection Luoyang Ship Material Research Institute (LSMRI) Instituto de estudios Avanzados IUdeA Departamento de Física Universidad de La Laguna C/Astrofísico Francisco Sanchez School of Chemistry and Chemical engineering Harbin Institute of Technology

Marine biofouling seriously affects human marine exploitation and transportation activities, to which marine antifouling(AF) coatings are considered to be the most cost-effective solution. Since the mid-20th century, human beings have.dedicated their efforts on developing AF coatings with long cycle and high performance, le.ding to a large number of non-target organisms? distortion, death and marine environmental pollution. Polydimethylsiloxane(PdMS), is considered as one of the representative environment-frie.dly AF materials thanks to its non-toxic, hydrophobic, low surface energy and AF properties. However, PdMS AF coatings are prone to mechanical damage, weak adhesion strength to substrate, and poor static AF effect, which seriously restrict their use in the ocean. The rapid development of various nanomaterials provides an opportunity to enhance and improve the mechanical properties and antifouling properties of PdMS coating by embe.ding *** on our research background and the problems faced in our laboratory, this article presents an overview of the current progress in the fie.ds of PdMS composite coatings enhanced by different nanomaterials, with the.discussion focused on the advantages and main bottlenecks currently encountered in this fie.d. Finally, we propose an outlook, hoping to provide fundamental guidance for the.development of marine AF fie.d.

关键词： Nanomaterials Antifouling PdMS composites environment-frie.dly Marine biofouling

Paper Analytical device for the Colourimetric detection of Alkaline Phosphatase in Serum and Saliva

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Analysis and Testing 2024年第3期8卷 385-394页

作者： d.Alageswari A.Lakshmidevi P.e.Resmi P.V.Suneesh AarathiPradeep T.G.SatheeshBabu department of Chemistry Amrita School of Physical Sciences Coimbatore Amrita Vishwa Vidyapeetham Amrita Biosensor Research Lab Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham Amrita Biomedical engineering Centre Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham

A paper analytical device (PAd) was developed for the colourimetric estimation of alkaline phosphatase (ALP). ALP catalyzes the hydrolysis of disodium phenyl phosphate (dSPP) to phenol, which then undergoes oxidative coupling with4-aminoantipyrine (4-AAP) producing a re.dish brown-coloured quinone imine. The colourimetric reaction tested in solution has been translated onto a PAd for the point of care (PoC) testing of ALP. A uniform colour was obtained in 25 min with the introduction of ALP onto the reagent drop cast paper device. The images obtained by scanning the PAd were processed using ImageJ software. The colour intensity obtained by image processing was proportional to the concentration of ALP present in the sample. ALP in serum and saliva samples were tested using the PAd in the range of 0 to 528 U/L and0 to 187 U/L, respectively. The interference studies revealed that the PAd was selective to ALP in the presence of other biomolecules. The PAd exhibited a limit of detection (LOd) of 3.3 U/L and a sensitivity of 48.36 a.u/Log(U/L) for serum ALP and LOd of 1.69 U/L and a sensitivity of 28.5 a.u/Log (U/L) for salivary ALP. The PAd showed good agreement with the clinical methods for real samples.

关键词： Alkaline phosphatase Colourimetry ImageJ Paper analytical device Point of care testing

experimental Assessment of the Thermal Performance of Two Corrugated Metal Roofs

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Applied Sciences 2024年第9期14卷 2374-2392页

作者： Kouamé Jean-louis Kouakou ekoun Paul Magloire Koffi Bi Tra désiré Zinla Prosper Gbaha Laboratoire.des Procds Industriels de Synthse de lEnvironnement et des Energies Nouvelles Institut National Polytechnique Felix Houphout-Boigny Yamoussoukro Cte dIvoire

This experimental study is a contribution to the search for solutions to reduce indoor heat gain through sheet metal roofing in hot weather. It has evaluated the thermal impact of two different sheet metal roofs inside of two identical test buildings in sunny weather and cloudy weather conditions. Test building 1 has a single sheet corrugated roof and the building 2 is covered with roof made from top to bottom with corrugated sheet metal, a 12 mm thick serpentine copper tube in which water is circulated, a sheet of aluminium foil acting as a heat reflector, a 4 cm thick polystyrene panel and a 1.5 cm thick plywood. A maximum reduction of 15.1˚C in the temperature of the inner face of the test Building 2 roof was obtained comparatively to the temperature of the inner face of the test Building 1 roof consisting of a single sheet of metal at the warmest hours. In addition, the simple corrugated sheet metal roof of the test building generates high and varied temperatures inside the building. Whereas the proposed heat recovery roof favours low and relatively uniform temperatures inside the building. The proposed sheet metal roof construction technique is very effective in reducing the heat gain through the roof considerably;thus improving the thermal comfort inside sheet metal roofed dwellings. Hot water has been produced by recovering heat from the metal sheet of the roof of test building 2. The temperature of the hot water produced reached of 39˚C. This study could be also an alternative for the reduction of energy consumption due to the use of mechanical means for cooling of sheet metal roofed houses and the reduction of the use of fossil fuels for domestic hot water production.

关键词： Metal Roof Corrugated Time Lag decrement Factor

Near-Infrared Fluorescence Imaging Contrast Agents for Clinical Research: Limitations and Alternatives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Biophysics 2024年第1期14卷 73-77页

作者： Serigne Moussa Badiane elhadji A. L. Bathily Fawrou Seye louis A.d. diouf department of Health Sciences Gaston BERGER University Saint-Louis Senegal department of Health Sciences Cheikh Anta DIOP University Dakar Senegal Cell Biology and Histology Health Sciences Department Gaston BERGER University Saint-Louis Senegal

Introduction: Near-infrared fluorescence imaging is a technique that will establish itself in the short term at the international level because it is recognized for its potential to improve the performance of surgical interventions, its moderate investment and operating costs and its portability. Although the technology is now mature, there is currently the problem of the availability of contrast agents to be injected IV. The aim of this methodology article is to propose an alternative solution to the ne.d for contrast agents for clinical research, particularly in oncology. Methodology: They consist of coupling a fluorescent marker in the form of an NHS derivative, such as IR dYe manufactured in compliance with GMP, with therapeutic monoclonal antibodies having marketing authorization for molecular imaging. For a given antibody, the marking procedure must be the subject of a validation file on the final preparation filtered on a sterilizing membrane at 0.22 μm. Once the procedure has been validated, it would be unnecessary to repeat the tests before each clinical research examination. A check of the marking by thin-layer chromatography (TLC) and place it in a sample bank at +4˚C for 1 month of each injected formulation would be sufficient for additional tests if necessary. Conclusion: Molecular near-infrared fluorescence imaging is experiencing development, the process of which could be accelerated by greater availability of clinical contrast agents. Alternative solutions are therefore necessary to promote clinical research in this area. These methods must be shared to make it easier for researchers.

关键词： Fluorescence Imaging Contrast Agents Clinical Research