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Epidemiological profile of alcoholic liver disease hospital admissions in a Latin American country over a 10-year period

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World Journal of Hepatology 2020年第5期12卷 230-238页

作者： Andre Castro Lyra lorena mascarenhas carneiro de almeida Yukari Figueroa Mise Lourianne Nascimento Cavalcante Gastro-Hepatology Service Hospital Sao RafaelSalvadorBahia 41253-190Brazil Gastro-Hepatology Service Hospital Universitario Prof.Edgard SantosFederal University of BahiaSalvadorBahia 40301-155Brazil de Saude Coletiva-Federal University of Bahia SalvadorBahia 40110-040Brazil

BACKGROUND Alcoholic liver disease(ALD)is a major cause of chronic liver disease *** To describe the epidemiological profile and mortality rates of patients with ALD admitted to public hospitals in different regions of Brazil from 2006 to *** This is a descriptive study that evaluated aggregate data from the five Brazilian geographic *** A total of 160093 public hospitalizations for ALD were *** was a 34.07%increase in the total number of admissions over 10 years,from 12879 in 2006 to 17267 in *** region with the highest proportion(49.01%)of ALD hospitalizations was Southeast(n=78463).The North region had the lowest absolute number of patients throughout the study period,corresponding to 3.9%of the total(n=6242).There was a 24.72%increase in the total number of ALD deaths between 2006 and *** found that the age group between 50 and 59 years had the highest proportion of both hospitalizations and deaths:28.94%(n=46329)of total hospital admissions and 29.43%(n=28864)of all *** were more frequently hospitalized than women and had the highest proportions of deaths in all *** coefficient rates increased over the years,and simple linear regression analysis indicated a statistically significant upward trend in this mortality(R^2=0.744).CONCLUSION Our study provides a landscape of the epidemiological profile of public hospital admissions due to ALD in *** detected an increase in the total number of admissions and deaths due to ALD over 10 years.

关键词： Alcoholic liver disease Epidemiology Mortality Liver Cirrhosis Hospital admissions

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An Application of the Taguchi Method (Robust design) to Environmental Engineering: Evaluating Advanced Oxidative Processes in Polyester-Resin Wastewater Treatment

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American Journal of Analytical Chemistry 2014年第13期5卷 828-837页

作者： Messias Borges Silva Livia Melo carneiro Jo&atilde o Paulo Alves Silva Ivy dos Santos Oliveira Hélcio José Izário Filho Carlos Roberto de Oliveira almeida department of Chemical Engineering School of Engineering of Lorena EEL S&atilde o Paulo University USP Lorena Brazil Production department Universidade Estadual Paulista-Faculdade de Engenharia do campus de Guaratinguetá—UNESP Guaratinguetá Brazil

This paper presents the Taguchi Method, a statistical design modelling for experiments applied in environmental engineering. This method was applied to optimize the treatment conditions of polyester-resin effluent by means of Advanced Oxidative Processes (AOPs) using chemical oxygen demand (COD) as response parameter. The influence of each independent parameter including respective interactions was evaluated by Taguchi Method, which allowed determining the most statistically significant variables and conditions to best fit the process. Results showed that Taguchi Method is a very useful tool for environmental engineering field and possible simplifications of analysis and calculations through commercially available software.

关键词： Taguchi Method Statistical Optimization Advanced Oxidative Processes Wastewater

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Influence of Agitation and Aeration on Single Cell Oil Production by Rhodotorula glutinis from Glycerol

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Journal of Sustainable Bioenergy Systems 2019年第2期9卷 29-43页

作者： Tatiane F.S.R.Bento Vitor F.M.Viana Livia M.carneiro Joao Paulo A.Silva department of Chemical Engineering Engineering College of LorenaUniversity of Sao PauloLorena/SPBrazil

In the present study, the yeast Rhodotorula glutinis has been assessed with the aim of producing microbial lipids from glycerol under different aeration conditions. For such a purpose, experiments were carried out in shake flasks, under different conditions of agitation (150 to 250 rpm) and aeration (2.5 to 5.0 of flask volume-to-medium volume ratio). Furthermore, their influence on fermentative parameters (lipid and cell concentration, biomass yield;lipid yield;and lipid volumetric productivity) has been investigated using a 22 full factorial design. The statistical analysis has revealed a strong influence of both variables on substrate consumption, lipid accumulation, cell growth and lipid productivity. As a whole, results suggest that higher aeration levels provide greater cell and lipid concentrations, and lipid volumetric productivity. The best results (4.5 g/L of lipids and QP = 0.95 g/L⋅day) were achieved at the highest aeration (5.0 flask volume-to-medium volume ratio) and agitation (250 rpm) levels. Their fatty acid profile showed that oleic acid was produced in greater quantity (53.5%), followed by linoleic acid (18.7%), palmitic acid (6.8%) and stearic acid (9.9%). The microbial oil presented viscosity of 39.3 cP at 50°C and free fatty acid content of 1.93% ± 0.08%. These are significant results and contribute to establishing operational conditions that maximize single-cell oil production from glycerol by Rhodotorula glutinis, i.e. an alternative source as renewable raw material for lipid-based biorefineries.

关键词： Single-Cell Oil Rhodotorula glutinis Aeration Glycerol Oleaginous Yeast

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