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Asian Pacific Journal of Tropical Medicine 2014年第11期7卷 895-899页

作者： Zhao-Xun Pan Hong-Xin Zhang Ye-Xin Wang long-di zhai Wei Du Department of Joint Surgery No 89 Hospital of People's Liberation Army

Objective:To observe the effect of recombinant human bone morphogenetic protein 2/polylactide-co-glycolic acid(rhBMP-2/PLGA) with core decompression on repair of rabbit femoral head ***:Bilateral femoral head necrosis models of rabbit were established by steroid injection.A total of 48 rabbits(96 femoral head necrosis) were randomly divided into 4groups:Group A,control group with12 rabbits,24 femoral head necrosis;Group B,treated with rhBMP-2/PLCA implantation after core depression,with 12 rabbits,24 femoral head necrosis;Group C,treated with rhBMP-2 implantation after core depression,with 12 rabbits,24 femoral head necrosis;Croup D treated with core depression group without implantation,with 12 rabbits,24 femoral head *** animals were sacrificed after 12 *** ability of repairing bone defect was evaluated by X-ray *** mineral density analysis of the defect regions were used to evaluate the level of *** morphologic change and bone formation was assessed by HE *** angiogenesis was evaluated by VEGF ***:The osteogenetic ability and quality of femoral head necrosis in group B were better than those of other groups after 12 weeks by X-ray radiograph and morphologic *** the angiogenesis in group B was better than other *** C had similar osteogenetic quality of femoral head necrosis and angiogenesis with group ***:The treatment of rhBMP-2/PLCA implantation after core depression can promote the repair of rabbit femoral head *** is a promising and efficient synthetic bone material to treat the femoral head necrosis.

关键词： rhBMP-2 Microsphere Core decompression Femoral head necrosis

On the Spectral Spread of Bicyclic Graphs with Given Girth

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Acta Mathematicae Applicatae Sinica 2013年第3期29卷 517-528页

作者： Bing WANG Ming-qing zhai Jin-long SHU School of Mathematical Science Chuzhou University Department of Mathematics East China Normal University

The spectral spread of a graph is defined to be the difference between the largest and the least eigenvalue of the adjacency matrix of the graph. A graph G is said to be bicyclic, if G is connected and ｜E（G）｜ = ｜V （G）｜＋ 1. Let B（n, g） be the set of bicyclic graphs on n vertices with girth g. In this paper some properties about the least eigenvalues of graphs are given, by which the unique graph with maximal spectral spread in B（n, g） is determined.

关键词： bicyclic graph least eigenvalue spectral spread

PlantCADB:A Comprehensive Plant Chromatin Accessibility Database

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Genomics, Proteomics & Bioinformatics 2023年第2期21卷 311-323页

作者： Ke ding Shanwen Sun Yang Luo Chaoyue long Jingwen zhai Yixiao zhai Guohua Wang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040China College of Information and Computer Engineering Northeast Forestry UniversityHarbin 150040China College of Life Science Northeast Forestry UniversityHarbin 150040China

Chromatin accessibility landscapes are essential for detecting regulatory elements,illustrating the corresponding regulatory networks,and,ultimately,understanding the molecular basis underlying key biological *** the advancement of sequencing technologies,a large volume of chromatin accessibility data has been accumulated and integrated for humans and other *** data have greatly advanced the study of disease pathogenesis,cancer survival prognosis,and tissue *** advance the understanding of molecular mechanisms regulating plant key traits and biological processes,we developed a comprehensive plant chromatin accessibility database(PlantCADB)from 649 samples of 37 *** samples are abiotic stress-related(such as heat,cold,drought,and salt;159 samples),development-related(232 samples),and/or tissue-specific(376 samples).Overall,18,339,426 accessible chromatin regions(ACRs)were *** ACRs were annotated with genomic information,associated genes,transcription factor footprint,motif,and single-nucleotide polymorphisms(SNPs).Additionally,PlantCADB provides various tools to visualize ACRs and corresponding *** thus forms an integrated,annotated,and analyzed plant-related chromatin accessibility resource,which can aid in better understanding genetic regulatory networks underlying development,important traits,stress adaptations,and evolution.

关键词： Chromatin accessibility Plant Transcription factor footprint Regulatory network Stress response

A Note on L(2,1)-labelling of Trees

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Acta Mathematicae Applicatae Sinica 2012年第2期28卷 395-400页

作者： Ming-qing zhai Chang-hong LU Jin-long SHU School of Mathematical Science Nanjing Normal University Jiangsu Nanjing 210046 China Department of Mathematics Chuzhou University Chuzhou 239012 China Department of Mathematics East China Normal University Shanghai 200241 China

An L（2, 1）-labelling of a graph G is a function from the vertex set V（G） to the set of all nonnegative integers such that │f（u） - f（v）│≥2 if dG（u, v） = 1 and │f（u） - f（v）│ ≥ 1 if dG（u, v） = 2. The L（2, 1）-labelling problem is to find the smallest number, denoted by A（G）, such that there exists an L（2, 1）-labelling function with no label greater than it. In this paper, we study this problem for trees. Our results improve the result of Wang [The L（2, 1）-labelling of trees, discrete Appl. Math. 154 （2006） 598-603].

关键词： distance-two labelling L(2, 1)-labelling tree

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北京天文台的三通道光子计数式高速光度计

Chinese Journal of Astronomy and Astrophysics 1982年第1期 56-62页

作者：王德隆翟迪生于建明孙敬颢唐小英赵复垣胡景耀北京天文台

一个利用光子计数方式的、可以同时对变星、比较星和天空背景进行测光的光度计已装于北京天文台兴隆工作站的60cm反光望远镜.它有一台专用计算机实时处理三个通道的数据,结果可以由打印机输出,对快变现象还可以在CRT或长图记录仪上显示... 详细信息

一个利用光子计数方式的、可以同时对变星、比较星和天空背景进行测光的光度计已装于北京天文台兴隆工作站的60cm反光望远镜.它有一台专用计算机实时处理三个通道的数据,结果可以由打印机输出,对快变现象还可以在CRT或长图记录仪上显示.光度计经过几年试用,已取得一些观测结果,表明性能基本满足天文观测的要求.

关键词：光电倍增管天文台积分时间光子计数量子光学三通道

Cucurbit[8]uril-regulated face-to-face dimerization assembly enhanced photosensitization and photocatalysis

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Science China Chemistry 2024年第5期67卷 1605-1612页

作者： Haigen Nie die Hu Zhiyao Zeng Yan Fan Yaxin zhai Xin-long Ni Key Laboratory of Chemical Biology and Traditional Chinese Medicine Ministry of Educational of ChinaKey Laboratory of the Assembly and Application of Organic Functional Molecules of Hunan ProvinceCollege of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081China Key Laboratory of Low-dimensional Quantum Structures and Quantum Control of Ministry of Education Department of PhysicsHunan Normal UniversityChangsha 410081China

In water, N,N′-diarylpyridinium thiazolo[5,4-d]thiazole guests(G1–G3) were encapsulated by cucurbit[8]uril(Q[8]) to construct Q[8]_(3)/G_(2) complexes, in which the encapsulated G molecules exist as an exact face-to-face dimer. These complexation behaviors have been indicated by proton nuclear magnetic resonance(~1H NMR) spectroscopy and isothermal titration calorimetry(ITC),and have been confirmed by X-ray single crystal structural analysis of Q[8]_(3)/G2_(2). While free guests G1–G3 have no ability to sensitize singlet oxygen, they all become effective singlet oxygen sensitizers when complexed with Q[8]. By irradiation of white light, Q[8]_(3)/G_(2) complexes induced selective oxidation of aryl sulfide to aryl sulfoxide in good yields and selective oxidation of dimethyl sulfide(DMS) to dimethyl sulfoxide(DMSO) in excellent yields without over-oxidation to dimethyl sulfone(DMSO_(2))even for elongated irradiation. High-yield photo-oxidation of DMS to DMSO_(2) was only achieved by irradiation of blue light in the presence of Q[8]_(3)/G1_(2), which was also effective in photobleaching of Rhodamine B in water. The higher photo-oxidation power of Q[8]_(3)/G1_(2) has been ascribed to an additional generation of reactive oxygen species besides singlet oxygen.

关键词： host-guest interaction dimerization macrocycles photosensitization

Storage and redistribution of anthropogenic CO_(2) in the western North Pacific:The role of subtropical mode water transportation

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Fundamental Research 2024年第1期4卷 103-112页

作者： Cheng-long Li Lei Han Wei-dong zhai di Qi Xu-chen Wang Hong-mei Lin Li-wen Zheng Institute of Marine Science and Technology Shandong UniversityQingdao 266237China China-ASEAN College of Marine Science and Technology Xiamen University MalaysiaSelangorMalaysia Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China Polar and Marine Research Institute Jimei UniversityXiamen 361021China Key Laboratory of Marine Chemistry Theory and Technology and Frontiers Science Center for Deep Ocean Multispheres and Earth SystemMinistry of EducationOcean University of ChinaQingdao 266100China Center for Isotope Geochemistry and Geochronology Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China Weihai Institute of Marine Ecology and Economy Research Weihai 264400China

Oceanic uptake and storage of anthropogenic CO_(2)(CANT)are regulated by ocean circulation and *** decipher the storage and redistribution of CANT in the western North Pacific,where a major CANT sink develops,we investigated the water column carbonate system,dissolved inorganic radiocarbon and ancillary parameters in May and August 2018,spanning the Kuroshio Extension(KE,35-39°N),Kuroshio Recirculation(KR,27-35°N)and subtropical(21-27°N)*** column CANT inventories were estimated to be 40.5±1.1 mol m^(-2) in the KR zone and 37.2±0.9 mol m^(-2) in the subtropical *** comparison with historical data obtained in 2005,relatively high rates of increase of the CANT inventory of 1.05±0.20 and 1.03±0.12 mol m^(-2) yr^(-1) in the recent decade were obtained in the KR and subtropical zones,*** water-mass-based analyses suggest that formation and transport of subtropical mode water dominate the deep penetration,storage,and redistribution of CANT in those two *** the KE zone,however,both the water column CANT inventory and the decadal CANT accumulation rate were small and uncertain owing to the dynamic hydrology,where the naturally uplifting isopycnal surfaces make CANT penetration relatively *** findings of this study improve the understanding of the spatiotemporal variations of CANT distribution,storage,and transport in the western North Pacific.

关键词： Oceanic CO_(2)uptake Anthropogenic CO_(2)storage Subtropical mode water Kuroshio extension Kuroshio recirculation Western North Pacific

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区域医疗系统抗震韧性综述

哈尔滨工业大学学报 2025年第1期57卷 1-12页

作者：裴顺顺翟长海胡杰结构工程灾变与控制教育部重点实验室(哈尔滨工业大学) 哈尔滨150090 土木工程智能防灾减灾工业和信息化部重点实验室(哈尔滨工业大学) 哈尔滨150090

韧性作为一种新的灾害风险管理理念,已成为防灾减灾领域的研究热点,考虑到医疗系统在城市运行和灾后救援中的重要作用,在地震期间和之后,区域医疗系统应该具有足够的韧性,并提供连续的医疗服务。如何综合考虑区域范围内多家医院和交通... 详细信息

韧性作为一种新的灾害风险管理理念,已成为防灾减灾领域的研究热点,考虑到医疗系统在城市运行和灾后救援中的重要作用,在地震期间和之后,区域医疗系统应该具有足够的韧性,并提供连续的医疗服务。如何综合考虑区域范围内多家医院和交通系统的安全性、应急响应能力、多系统的整合与协作,有效评估区域医疗系统的抗震韧性水平,并提出科学的改进建议,对建设韧性城乡具有重要的理论意义。本文通过梳理国内外文献,阐明了区域医疗系统韧性的概念和内涵,总结了地震后短期应急和长期修复两个阶段韧性评估的重点,归纳了现有区域医疗系统韧性的评估框架,从医院集群系统、面向医疗的交通系统、应急医疗服务系统和医疗-交通耦合系统4个方面阐述了现有评估方法。区域医疗系统韧性的研究旨在提高其面对灾害时的抵抗性、短期适应性和长期恢复性,这些研究对于满足紧急和日常的医疗需求以及指导灾后恢复具有重要意义。目前区域医疗系统抗震韧性的研究取得了一些进展,但仍然存在一些挑战,本文最后展望了未来的研究方向。

关键词：区域医疗系统单体医院交通系统抗震韧性功能评估恢复时间

Glioma cell line proliferation controlled by different chemical functional groups in vitro

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Frontiers of Materials Science 2013年第1期7卷 69-75页

作者： Su-Ju XU Fu-zhai CUI Xiao-long YU Xiang-Dong KONG Xinyuan Institute of Medicine and Biotechnology School of Life Science Zhejiang Sci-Tech University Hangzhou 310018 China Institute of Regenerative Medicine anclBiomimetic Materials Department of Materials Science and Engineering Tsinghua University Beijing 100084 China

Glioma cell line C6 cultured on silicon surfaces modified by different chemical functional groups, including mercapto (-SH), carboxyl (-COOH), amino (-NH2), hydroxyl (-OH) and methyl (-CH3) groups, was studied here to investigate the influence of surface chemistry on the cell proliferation, adhesion and apoptosis. AFM confirmed the similar characteristic of different functional groups occupation. The adhering C6 exhibited morphological changes in response to different chemical functional groups. The C6 adhered to -COOH, -NH2, -OH and -CH3 surfaces and flattened morphology, while those on -SH surface exhibited the smallest contact area with mostly rounded morphology, which led to the death of cancer cells. The results of MTT assay showed that the -COOH and -NH2 groups promoted cell proliferation, while the -SH significantly inhibited the proliferation. Compared with other chemical functional groups, the -SH group exhibited its unique effect on the fate of cancer cells, which might provide means for the design of biomaterials to prevent and treat glioma.

关键词： glioma cell line C6 chemical functional group adhesion proliferation

Wolfberry tree dual-model detection method and orchard target-oriented fertilization system based on photoelectric sensors

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International Journal of Agricultural and Biological Engineering 2018年第4期11卷 65-73页

作者： Shuo Yang Changyuan zhai John long Bo Zhang Hanzhe Li College of Mechanical and Electronic Engineering Northwest A&F UniversityYangling 712100China Key Laboratory of Agricultural Internet of Things Ministry of Agriculture and Rural AffairsYanglingShaanxi 712100China Department of Biosystems and Agricultural Engineering Oklahoma State UniversityStillwaterOK 74078USA

Orchard target-oriented fertilizing with on-board sensor technology can improve fertilizer efficiency and reduce environmental *** sensors are widely used for object detection because of their low cost and fast response *** paper presents a Wolfberry tree dual-model detection method and the design of an orchard target-oriented variable-rate fertilization system based on photoelectric *** dual-model detection method includes the Trunk Detection Model(TDM)and Canopy Detection Model(CDM),which can be applied for Wolfberry orchards at the green cluster and mature stages,respectively.A target-oriented fertilization system was designed using the dual-model method,and tested in the lab and Chinese Wolfberry *** laboratory test results showed that the average center offset distances on the condition of detecting trunks,continuous canopies,and discontinuous canopies were 4.1 cm,9.1 cm and 13.1 cm,*** system could ignore the signals from canes when their diameters were less than 16 mm,and also could determine the gaps within a tree when they were less than 21 *** orchard test results showed that the system accomplished target-oriented fertilization 95 times for 92 trees at the mature *** results indicated that the dual-model detection method could be used for Wolfberry trees or other trees with similar canopy changes at different growth stages.

关键词： orchard fertilizer target-oriented fertilization variable rate fertilization photoelectric sensor wolfberry orchard