检索结果-南通市图书馆

Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression

引用

Neural Regeneration Research 2025年第11期20卷 3259-3272页

作者： Huidong Li Faqin Li Zhaoyi Chen Erwen Wu Xiaoxi Dai Danni Li Haojie An Shiyi Zeng Chunyan Wang Li Yang cheng long School of Life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina School of Life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Major Obstetric Diseases The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina

Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear ***(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B *** is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly *** studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like ***,the precise role of CYLD in glutamatergic neurons is largely ***,we first proposed involvement of CYLD in cued fear *** next constructed transgenic model mice with specific deletion of Cyld from glutamatergic *** results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male ***,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male ***,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial *** may contribute,at least in part,to cued fear expression.

关键词： basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Optimal Resource Allocation and Feasible Hexagonal Topology for Cyber-Physical Systems

引用

Journal of Systems Science & Complexity 2023年第4期36卷 1583-1608页

作者： LIU Yifa cheng long State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China

Networked cyber-physical systems are facing serious security threats from malicious *** is noted that the networked cyber-physical system should take defense measures into account at the beginning of its *** the conservative defensive perspective,this paper proposes a robust optimal defense resource allocation strategy to reduce the maximum possible losses of the networked cyber-physical system caused by potential ***,based on the robust optimal allocation strategy,it can be proved that the topology of the networked cyber-physical system has a great influence on the loss *** order to further improve security,the effects of adding redundant connections are ***,by taking geographical knowledge into account,a hexagonal construction scheme is proposed for providing a geographically-feasible and economically-viable solution for building networked cyber-physical systems,where the loss function has a cubic decay.

关键词： Cyber-physical system hexagonal city planning optimization resource allocation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Photocatalytic activation of sulfite by N-doped porous biochar/MnFe_(2)O_(4) interface-driven catalyst for efficient degradation of tetracycline

引用

Green Energy & Environment 2024年第3期9卷 481-494页

作者： long cheng Yuanhui Ji Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research School of Chemistry and Chemical EngineeringSoutheast UniversityNanjing211189China

A novel photo-catalytic system composed of N-doped biochars(NBCs),MnFe_(2)O_(4) and sulfite activation under ultraviolet(NBCs/MnFe_(2)O_(4)/sulfite/UV)was constructed to realize the efficient eliminate of tetracycline(TC).As the carrier of MnFe_(2)O_(4),NBCs were synthesized from alfalfa,which has large specific surface area,graphite like structure and hierarchical porous *** adsorption isotherm indicated that NBCs/MnFe_(2)O_(4)-2:1 had the best adsorption performance for TC(347.56 mg g^(-1)).Through synergistic adsorption and photocatalysis,the removal rate of TC reached 84%,which was significantly higher than that of MnFe_(2)O_(4).Electrochemical impedance spectroscopy(EIS)and Photoluminescence(PL)characterization results showed that the introduction of NBCs improved the separation efficiency of photogenerated electron and hole pairs and enhanced the photocatalytic ***,the adsorption,degradation mechanism and degradation path of TC by the catalyst were systematically analyzed by coupling HPLC–MS measurement with the theoretical *** the advantages of excellent degradation performance,low cost,easy separation and environmental friendliness of NBCs/MnFe_(2)O_(4),this work was expected to provide a new path for the practical application of biochar.

关键词： Biochar MnFe_(2)O_(4) Sulfite Adsorption Photocatalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adaptive Takagi-Sugeno fuzzy model and model predictive control of pneumatic artificial muscles

引用

Science China(Technological Sciences) 2021年第10期64卷 2272-2280页

作者： XIA XiuZe cheng long School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory for Management and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China

Pneumatic artificial muscles(PAMs)usually exhibit strong hysteresis nonlinearity and time-varying features that bring PAMs modeling and control *** characterize the hysteresis relation between PAMs’displacement and fluid pressure,a long short term memory(LSTM)neural network model and an adaptive Takagi-Sugeno(T-S)fuzzy model are *** show that both models perform well under the load free conditions,and the adaptive T-S Fuzzy model can furtherly adapt to the change of load with the online adaptation *** the concise expression and satisfactory performance of the adaptive T-S Fuzzy model,a model predictive controller is designed and *** show that the model predictive controller has a good performance on tracking the given references.

关键词： pneumatic artificial muscles adaptive T-S fuzzy model LSTM neural network model model predictive control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SP3-Hybridization Feature of Ag4 Superatom in Superatomic Molecules

引用

Chinese Journal of Chemical Physics 2015年第4期28卷 -页

作者： Li-juan Yan long-jiu cheng Jin-long Yang Hefei National Laboratory of Physical Science at the Microscale University of Science and Technology of China Hefei 230026 China Department of Chemistry Anhui University Hefei 230601 China Hefei National Laboratory of Physical Science at the Microscale University of Science and Technology of China Hefei 230026 ChinaSynergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China Hefei 230026 China

Analogous to atoms, superatoms can be used as building blocks to compose molecules and materials. To demonstrate this idea, the possibility of using tetrahedral Ag4 cluster to form a series of superatomic molecules Ag4X4 (X=H, Li, Na, K, Cu, Ag, Au and F, Cl, Br) is discussed. Based on the super valence bond model, a tetrahedral Ag4 cluster can be viewed as a 4-electron superatom, which can mimic a sp3 hybridization C atom. By comparison of the representative superatomic molecules Ag4X4 (X=Au, Cl) with the corresponding simple molecules CX4 (X=H, Cl), the similarities in terms of chemical bonding patterns and molecular orbitals (MOs) are conspicuous. Energy calculations predict that the Ag4 superatom can bind with all the involved ligands. Furthermore, the stabilities of superatomic molecules are enhanced by the large gaps of the highest occupied molecular orbital and the lowest unoccupied molecular orbital (HOMO-LUMO gaps) and high aromaticity. Our studies may find applications in assembling materials with superatoms.

关键词： Superatom Magic numbers Super valence bond Binding energy Aromaticity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Iterative assist-as-needed control with interaction factor for rehabilitation robots

引用

Science China(Technological Sciences) 2021年第4期64卷 836-846页

作者： CAO Ran cheng long YANG chenguang DONG Zhe School of Artificial Intelligence University'of Chinese Academy of SciencesBeijing 100049China State Key Laboratory for Management and Control of Complex Systems Institute of Automation.Chinese Academy of SciencesBeijing 100190China School of Automation Science and Engineering South China University of TechnologyGuangzhou 510641China School of Electrical and Control Engineering North China Universityof TechnologyBeijing 100144China

Rehabilitation robots for stroke patients have drawn considerable attention because they can reduce the economic and labor costs brought by traditional rehabilitation. Control methods for rehabilitation robots have been developed to stimulate the active motion of patients and to improve the effectiveness of rehabilitation care. However, current control methods can only roughly adjust the system’s stiffness and may fail in achieving satisfactory performance. To this end, this paper introduces a novel cost function consisting of the tracking error term and the stiffness term. The cost function contains an interaction factor that represents the patient’s motion intention to balance the weight of these two terms. When the patients try to actively do training tasks, the weight of stiffness term increases, which leads to the larger allowable tracking error and lower stiffness eventually. An iterative updating law of the stiffness matrix is given to reduce the proposed cost function. Theoretical analysis based on the Lyapunov theory is given to ensure the feasibility of the proposed algorithm. Furthermore, a force estimation is used to improve interaction control performance. Finally, simulation experiments are provided to show the effectiveness of the proposed algorithm.

关键词： human-robot interaction impedance stiffness control rehabilitation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis of hierarchical SAPO-11-based catalysts with Al-based metal-organic framework derivative as mesoporogen to improve n-decane branched isomerization

引用

Petroleum Science 2022年第6期19卷 3171-3181页

作者： Xue-Man Wang cheng-long Wen Yu Fan State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Advanced Catalysis and Green Manufacturing Collaborative Innovation Centerand School of Petrochemical EngineeringChangzhou UniversityChangzhouJiangsu213164China

Hierarchical SAPO-11 molecular sieve(ACS-11) was successfully synthesized employing the Al2O3/carbon(Al_(2)O_(3)/C) composite obtained through the pyrolysis of Al-based metal-organic framework(Al-MOF-96)as *** other carbon-based mesoporogens with strong hydrophobicity,the Al_(2)O_(3)/C interacts with phosphoric acid and generates the AlPO_(4)/C structure,which promotes the Al2O3/C dispersion in the synthesis gel of SAPO-11 and avoids the phase separation between *** Al_(2)O_(3)/C as mesoporogen decreases the crystallite size of SAPO-11 via preventing the aggregation of ***,the addition of Al_(2)O_(3)/C improves the Si distribution in the ACS-11 ***,ACS-11 has smaller crystallites,more mesopores,and a greater amount of medium Bronsted acid centers than the conventional microporous SAPO-11 and the SAPO-11 synthesized using activated carbon as *** corresponding Pt/ACS-11 catalyst exhibits the maximal selectivity to multi-branched C10isomers(23.28%) and the minimal cracking selectivity(15.83%) in n-decane hydroisomerization among these *** research provides a new approach for preparing hierarchical silicoaluminophosphate molecular sieve-based catalysts to produce high-quality fuels.

关键词： Hierarchical SAPO-11 Al_(2)O_(3)/C composite Hydroisomerization Branched isomers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel sliding-mode disturbance observer-based tracking control with applications to robot manipulators

引用

Science China(Information Sciences) 2021年第7期64卷 80-91页

作者： Tairen SUN long cheng Zengguang HOU Min TAN School of Electrical and Information Engineering Jiangsu University State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of Sciences School of Artificial Intelligence University of Chinese Academy of Sciences

This paper proposes a sliding-mode disturbance observer(SMDOB)-based tracking controller for a class of nonlinear systems with modeling uncertainties and external disturbances. The SMDOB is constructed using an extended state observer embedded by a filtered sliding mode term. The chattering caused by the sliding mode is compressed by the frequency bandwidths of both the extended state observer and the control system. The novelties of the proposed controller are as follows:(1) The semiglobal asymptotical stability of the combined controller-observer system is guaranteed without the boundedness assumption of the time derivatives of modeling uncertainties;(2) the SMDOB can be implemented with a low complexity because of only three parameters to be tuned. Applications to robot manipulators illustrate the effectiveness of the SMDOB-based tracking control strategy.

关键词： adaptive control robot manipulator disturbance observer sliding mode

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Multi-modal fusion for robust hand gesture recognition based on heterogeneous networks

引用

Science China(Technological Sciences) 2023年第11期66卷 3219-3230页

作者： ZOU YongXiang cheng long HAN LiJun LI ZhengWei School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory for Management and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China

Hand gesture recognition has become a vital subject in the fields of human-computer interaction and rehabilitation *** paper presents a multi-modal fusion for hand gesture recognition(MFHG)model,which uses two heterogeneous networks to extract and fuse the features of the vision-based motion signals and the surface electromyography(s EMG)signals,*** extract the features of the vision-based motion signals,a graph neural network,named the cumulation graph attention(CGAT)model,is first proposed to characterize the prior knowledge of motion coupling between finger *** CGAT model uses the cumulation mechanism to combine the early and late extracted features to improve motion-based hand gesture *** the s EMG signals,a time-frequency convolutional neural network model,named TF-CNN,is proposed to extract both the signals'time-domain and frequency-domain *** improve the performance of hand gesture recognition,the deep features from multiple modes are merged with an average layer,and then the regularization items containing center loss and the mutual information loss are employed to enhance the robustness of this multi-modal ***,a data set containing the multi-modal signals from seven subjects on different days is built to verify the performance of the multi-modal *** experimental results indicate that the MFHG can reach 99.96%and 92.46%accuracy on hand gesture recognition in the cases of within-session and cross-day,respectively.

关键词： leap motion s EMG multi-modal graph neural network hand gesture recognition

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neural Liénard system: learning periodic manipulation skills through dynamical systems

引用

Science China(Information Sciences) 2024年第12期67卷 256-271页

作者： Haoyu ZHANG long cheng Yu ZHANG Yifan WANG School of Artificial Intelligence University of Chinese Academy of Sciences State Key Laboratory for Multi-modal Artificial Intelligence Systems Institute of AutomationChinese Academy of Sciences

Learning from demonstrations provides effective methods for teaching robot manipulation ***, capturing periodic manipulation skills remains challenging with the current techniques. To address this gap, we introduce the neural Liénard system(neural LS), a novel neural network framework that utilizes Liénard-type differential equations to create dynamical systems with stable and distinct limit cycles. We also introduce an innovative technique, which not only manages periodic trajectories across various dimensions but also handles trajectories with intersections, enhancing the capability of the robot for complex tasks. We provide a thorough theoretical analysis of neural LS, focusing on its stability and representational *** evaluations show that neural LS achieves superior performance in modeling complex limit cycles,surpassing the existing methods. We particularly emphasize its effectiveness in handling high-dimensional periodic motions and trajectories with intersections. In addition, we explore the adaptability and robustness of neural LS. A practical application involving the Franka Emika robot in a drawing task further demonstrates the real-world utility of neural LS, confirming its effectiveness and potential to equip robots with advanced periodic manipulation skills.

关键词： learning from demonstrations stable dynamical system periodic motions

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：