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Importance of Air-Sea Coupling in Simulating Tropical Cyclone Intensity at Landfall

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Advances in Atmospheric Sciences 2022年第10期39卷 1777-1786页

作者： Charlie C.F.lok Johnny C.L.CHAN Ralf TOUMI School of Energy and Environment City University of Hong KongHong KongChina Department of Physics Imperial CollegeLondon SW72AZUK

An atmosphere-only model system for making seasonal prediction and projecting future intensities of landfalling tropical cyclones(TCs)along the South China coast is upgraded by including ocean and wave models.A total of 642 TCs have been re-simulated using the new system to produce a climatology of TC intensity in the South China *** comparisons of the simulations from the atmosphere-only and the fully coupled systems reveal that the inclusion of the additional ocean and wave models enable differential sea surface temperature responses to various TC characteristics such as translational speed and *** particular,interaction with the ocean does not necessarily imply a weakening of the TC,with the coastal bathymetry possibly playing a role in causing a near-shore intensification of the *** results suggest that to simulate the evolution of TC structure more accurately,it is essential to use an air-sea coupled model instead of an atmosphere-only model.

关键词： tropical cyclone intensity tropical cyclone landfall seasonal prediction air-sea coupling

Temperature-and thickness-dependence of robust out-of-plane ferroelectricity in CVD grown ultrathin van der Waals a-In2Se3 layers

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Nano Research 2020年第7期13卷 1897-1902页

作者： Weng Fu Io Shuoguo Yuan Sin Yi Pang lok Wing Wong Jiong Zhao Jianhua Hao Department of Applied Physics The Hong Kong Polytechnic UniversityHong KongChina

Two-dimensional(2D)ferroelectric materials with unique structure and extraordinary optoelectrical properties have attracted intensive research in the field of nanoelectronic and optoelectronic devices,such as optical sensors,transistors,photovoltaics and non-volatile memory ***,the transition temperature of the reported ferroelectrics in 2D limit is generally low or slightly above room temperature,hampering their applications in high-temperature electronic ***,we report the robust high-temperature ferroelectricity in 2D a-In2Se3,grown by chemical vapor depostion(CVD),exhibiting an out-of-plane spontaneous polarization reaching above 200℃.The polarization switching and ferroelectric domains are observed in In2Se;nanoflakes in a wide temperature *** coercive field of the CVD grown ferroelectric layers ilustrates a room-temperature thickness dependency and increases drastically when the film thickness decreases;whereas there is no large variance in the coercive field at dfterent termperature from the samples with identical *** results show the stable ferroelectricit of In2Se3 nanoflakes maintained at high temperature and open up the opportunities of 2D materials for novel applications in high-temperature nanoelectronic devices.

关键词： ln2Se3 two-dimensional(2D)materials ferroelectricity high-temperature coercive field

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宮頸液基細胞學檢測原發性宮頸淋巴瘤1例

镜湖医学 2024年第1期24卷 61-61,60,F0004页

作者：陳頌敏李文洛陳建勇澳門鏡湖醫院病理科中国

原發女生殖系統淋巴瘤較少見,佔全身結外淋巴瘤1%[1],其中原發性宮頸淋巴瘤(primary cervical lymphoma,PCL)更是罕見的婦科惡性腫瘤,佔宮頸腫瘤0.008%[2,3]。宮頸淋巴瘤起源於宮頸黏膜淋巴組織,症狀包括陰道出血、白帶增多、下腹痛和... 详细信息

原發女生殖系統淋巴瘤較少見,佔全身結外淋巴瘤1%[1],其中原發性宮頸淋巴瘤(primary cervical lymphoma,PCL)更是罕見的婦科惡性腫瘤,佔宮頸腫瘤0.008%[2,3]。宮頸淋巴瘤起源於宮頸黏膜淋巴組織,症狀包括陰道出血、白帶增多、下腹痛和盆腔腫塊,與其他婦科疾病症狀相似,容易誤診。

关键词：淋巴瘤女生殖系下腹痛液基

Corneal injection track: an unusual complication of intraocular lens implantation and review

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International Journal of Ophthalmology(English edition) 2015年第3期8卷 631-633页

作者： Julie Y.C.lok Alvin L.Young Department of Ophthalmology & Visual Sciences the Chinese University of Hong Kong Prince of Wales Hospital Alice Ho Miu Ling Nethersole Hospital

Phacoemulsification is the main gold standard for cataract operation in the developed world together with foldable intraocular lens(IOL) implantation by injection,allowing for stable wound construction and less postoperative astigmatism. It is a safe procedure with high success rate with the advancement in machines,improvement of IOL injection systems and further maturation of surgeons’ techniques. Despite the large number of operations performed every day, foldable IOL injection leading to an intra-stromal corneal track is a very rare complication. We report a case of this unusual finding in a 70-year-old gentleman who has undergone cataract operation in November 2011 in our hospital and will review on the complications related to foldable IOL injection.

关键词： foldable intraocular lens phacoemulsification cornea complications

Revisiting oral fluoropyrimidine with cetuximab in metastatic colorectal cancer: Real-world data in Chinese population

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World Journal of Gastrointestinal Oncology 2019年第11期11卷 1031-1042页

作者： Ka-On Lam Man-Chi Fu Kin-Sang Lau Kam-Mo Lam Cheuk-Wai Choi Wan-Hang Chiu Cheng-Man Yuen Lai-Han Kwok Fong-Kit Tam Wing-lok Chan sum-Yin Chan Pui-Ying Ho To-Wai Leung Ho-Fun Lee Department of Clinical Oncology LKS Faculty of MedicineThe University of Hong KongHong KongChina Department of Clinical Oncology Queen Mary HospitalHong KongChina Clinical Oncology Centre The University of Hong Kong-Shenzhen HospitalShenzhen 518053Guangdong ProvinceChina Department of Pharmacy Queen Mary HospitalHong KongChina Department of Diagnostic Radiology LKS Faculty of MedicineThe University of Hong KongHong KongChina

BACKGROUND Cetuximab in combination with oral fluoropyrimidine(FP)remains controversial in metastatic colorectal cancer(mCRC).In view of the regional variation in the tolerability of FP,we conducted a retrospective analysis to compare oral FP with infusional FP in combination with cetuximab in Chinese *** To compare the efficacy and safety profile of cetuximab in combination with oral FP and infusional FP in Chinese population in the real-world *** A retrospective cohort study was done to analyse consecutive patients with Kras wild-type mCRC who received first-line treatment with cetuximab and FP-based chemotherapy in our unit from January 2010 to December ***-five eligible patients were *** median follow-up of our cohort was 65.0 *** The median progression-free survival(mPFS)and median overall survival(mOS)of the entire cohort were 9.66 mo(95%CI:7.72–12.5)and 25.8 mo(95%CI:18.7–35.6),*** oral FP and infusional FP,there was no statistical significant difference in the mPFS[9.79 mo(95%CI:7.49–12.7)vs 9.63 mo(95%CI:6.34–13.4);P=0.72]and mOS[25.8 mo(95%CI:15.2–35.6)vs 26.3 mo(95%CI:18.7–41.2);P=0.63].Grade 3 or above adverse events were reported in 28.4%of patients,being similar with oral and infusional FP,and included 10.5%of neutropenia and 2.1%of diarrhoea *** The current analysis demonstrates comparable efficacy and safety profiles of cetuximab in combination with oral and infusional FP in Chinese *** results expand treatment options for Chinese patients and invite revision of existing treatment guidelines to incorporate oral FP-based chemotherapy plus cetuximab.

关键词： Capecitabine 5-Fluorouracil Cetuximab Metastatic colorectal cancer Chinese

MECHANICAL PROPERTIES OF HYBRID GLASS/SUGAR PALM FIBRE REINFORCED UNSATURATED POLYESTER COMPOSITES

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Chinese Journal of Polymer Science 2013年第10期31卷 1394-1403页

作者： S.M.Sapuan H.Y.lok M.R.Ishak S.Misri Department of Mechanical and Manufacturing Engineering Universiti Putra Malaysia43400 UPM Serdang Selangor Malaysia Institute of Advanced Technology (ITMA) Universiti Putra Malaysia43400 UPM Serdang Selangor Malaysia Institute of Tropical Forestry and Forest Products (INTROP) Universiti Putra Malaysia43400 UPM SerdangSelangor Malaysia Faculty of Engineering and Technology Multimedia UniversityJalan Ayer Keroh Lama75450 Bukit Beruang Melaka Malaysia Department of Aerospace Engineering Universiti Putra Malaysia43400 UPM Serdang Selangor Malaysia

A research has been carried out to investigate the mechanical properties of composites made by hybridizing sugar palm fibre （Arenga pinnata） with glass fibre into an unsaturated polyester matrix. Hybrid composites of glass/sugar palm fibre were fabricated in different weight ratios of strand mat glass fibres ： sugar palm fibres 4：0, 4：1, 4：2, 4：3, 4：4, and 0：4. The hybrid effects of glass and sugar palm fibre on tensile, flexural and impact properties of the composites were evaluated according to ASTM D5083, ASTM D790 and ASTM D256 respectively. Results have been established that properties of hybrid glass/sugar palm composites such as tensile strength, tensile modulus, elongation at break, toughness, flexural strength, flexural modulus and impact strength are a function of fibre content. The failure mechanism and the adhesion between fibres/matrix were studied by observing the scanning electron micrographs of impact fracture samples. In general, the incorporation of both fibres into unsaturated polyester matrix shows a regular trend of increase in the mechanical properties.

关键词： Tensile test Flexural test Impact test Hybrid composite Sugar palm fibre.

Design and rationale of a randomized-controlled trial of home-delivered meals for the management of symptomatic ascites:the SALTYFOOD trial

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Gastroenterology Report 2019年第2期7卷 146-149,I0002页

作者： Elliot B.Tapper Jad Baki Scott Hummel Anna lok Division of Gastroenterology and Hepatology Department of Internal MedicineUniversity of MichiganAnn ArborMichiganUSA University of Michigan Ann ArborMichiganUSA Division of Cardiology Department of Internal Medicine University of MichiganAnn ArborMichiganUSA

Background:When patients with cirrhosis develop ascites,it is associated with sharply increasedmortality and healthcare utilization with decreased quality of *** salt restriction is first-line therapy for ascites but it is limited by poor ***:We will recruit 40 patients with cirrhosis and ascites who have received a recent paracentesis or hospitalization for a 1:1 randomized trial of standard care(education on salt restriction)versus home-delivered *** primary outcome is the number of paracenteses needed over 12 *** outcomes include hospital-bed days,health-related quality of life(HRQOL,Ascites Symptom Inventory-7 and Visual Analogue Scale)and performance on batteries of physical function including hand grip(kg)and walk speed(m/s).All subjects follow up through a series of calls where any paracenteses,hospital readmissions,weight changes and diuretic dosage changes are *** a final Week 12 visit,knowledge of dietary sodium intake,quality of life and frailty are reassessed,and satisfaction with the meal-delivery program is *** comparison testing will be conducted between the two ***:A nutritionally standardized meal-delivery program for patients with cirrhosis and ascites post discharge has a variety of potential patient-based benefits,including the effective management of ascites,reduction of healthcare utilization and improvement of *** have three core ***,patients will report interest in and satisfaction with a home-delivered meals ***,subjects on a salt-restricted(2 g sodium)meal-delivery program will have fewer therapeutic paracenteses and all-cause readmissions than subjects receiving standard of ***,subjects on a saltrestricted(2 g sodium)meal-delivery program will report increased HRQOL compared to subjects receiving standard of care.

关键词： Readmissions malnutrition cirrhosis nutrition sodium

Assessing the kinetic model of hydro-distillation and chemical composition ofAquilaria malaccensis leaves essential oil

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Chinese Journal of Chemical Engineering 2017年第2期25卷 216-222页

作者： Mahtab Samadi Zurina Zainal Abidin Robiah Yunus Dayang Radiah Awang Biak Hiroyuki Yoshida Eng Hai lok Department of Chemical and Environmental Engineering Faculty of EngineeringUniversity Putra MalaysiaserdangSelangorDaml Ehsan 43400Malaysia Aerospace Manufacturing Research Centre(AMRC) Level 7Tower BlockFaculty of EngineeringUniversity Putra Malaysia43400 5erdang SelangorMalaysia Forest Research Institute Malaysia 52109 Kepong5elangorDarul EhsanMalaysia

This study aimed to model the kinetic of hydro-distillation of Aquilaria malaccensis leaves oil in order to understand and optimize the extraction process. In addition, this study, for the first time, aimed to identify the chemical compositions of the A. rnalaccensis leave-oil. By assessing both first-order kinetic model and the model of simultaneous washing and diffusion, the result indicated that the model of simultaneous washing and diffusion better describes the hydro-distillation mechanism of the essential oil from A. rnalaccensis leaves. The optimum time, solid to liquid ratio, and the heating power for extracting the highest amount of essential oil were found to be around 3 h, 1：10 （g. ml-1）, and 300 W respectively. Yellow essential oil with a strong smell and a yield of 0.05 v/w was extracted by hydro-distillation Clevenger apparatus. Chemical compounds of the essential oil were analyzed using gas chromatography-mass spectroscopy （GC/MS）, which resulted in identification of 42 compounds that constitute 93% of essential oil. Among the identified components, Pentadecanal （32.082%）, 9-Octadecenal, （Z）（15.894%）, and Tetradecanal （6.927%） were the major compounds. Considering the fact that all the identified major components possess pesticidal properties, A. malaccensis leaves can be regarded as a promising natural source for producing pesticides.

关键词： Aquilaria malaccensisEssential oilHydro-distillationOptimizationKinetic modeling

Evaluation of referrals for genetic investigation of short stature in Hong Kong

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Chinese Medical Journal 2002年第4期 127-131页

作者： LAM Wai Fan Fanny, HAU Wai lok Edgar and LAM Tak sum Stephen Clinical Genetic Service, Department of Health, Hong Kong Special Administrative Region, China (Lam WFF, Hau WLE and Lam TSS)

To establish a profile of the causes of apparently unexplained SS in genetic ref erral center and evaluate the current referral system Methods This was a retrospective database survey on patients who were referred our clini cal genetic service from 1988-1998 primarily because of SS We retrieved the st udy population from our computer database using "short stature" as a search han dle and then studied the demographic, clinical and laboratory data from their me dical records Results Three hundred and fifty three subjects were referred for genetic evaluation of SS in 1988-1998 The mean age of referred subjects was 11 5 years and the female to male ratio was 7 6 All referrals had undergone cytogenetic studies to exclude chromosomal abnormal ities, 19% of girls with apparently unexplained short stature had Turner syndrom e; at least 47 9% of the study population were normal variants and 25% of the referrals had inadequate information for classification Conclusions Genetic investigation is essential in the management of patients with SS, especi ally for girls suspected of having Turner syndrome, in which growth hormone trea tment has shown to improve final height We also highlight the inherited causes of short stature, which were often misdiagnosed as benign familial short statur e, and discussed the drawbacks of the current referral

关键词： genetic investigation · etiology · short stature