检索结果-南通市图书馆

Examining patterns of traditional chinese medicine use in pediatric oncology: A systematic review, meta-analysis and data-mining study

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Journal of Integrative Medicine 2022年第5期20卷 402-415页

作者： Chun Sing Lam Li Wen Peng lok sum yang Ho Wing Janessa Chou Chi-Kong Li Zhong Zuo Ho-Kee Koon Yin Ting Cheung School of Pharmacy Faculty of Medicinethe Chinese University of Hong KongHong KongChina Department of Paediatrics Faculty of Medicinethe Chinese University of Hong KongHong KongChina Hong Kong Hub of Paediatric Excellence the Chinese University of Hong KongHong KongChina Department of Paediatrics&Adolescent Medicine Hong Kong Children’s HospitalHong KongChina School of Chinese Medicine Faculty of Medicinethe Chinese University of Hong KongHong KongChina

Background Traditional Chinese medicine(TCM)is becoming a popular complementary approach in pediatric ***,few or no meta-analyses have focused on clinical studies of the use of TCM in pediatric *** We explored the patterns of TCM use and its efficacy in children with cancer,using a systematic review,meta-analysis and data mining *** strategy We conducted a search of five English(Allied and Complementary Medicine Database,Embase,PubMed,Cochrane Central Register of Controlled Trials,and ***)and four Chinese databases(Wanfang Data,China National Knowledge Infrastructure,Chinese Biomedical Literature Database,and VIP Chinese Science and Technology Periodicals Database)for clinical studies published before October 2021,using keywords related to“pediatric,”“cancer,”and“TCM.”Inclusion criteria We included studies which were randomized controlled trials(RCTs)or observational clinical studies,focused on patients aged<19 years old who had been diagnosed with cancer,and included at least one group of subjects receiving TCM *** extraction and analysis The methodological quality of RCTs and observational studies was assessed using the six-item Jadad scale and the Effective Public Healthcare Panacea Project Quality Assessment Tool,***-analysis was used to evaluate the efficacy of combining TCM with *** outcomes included the treatment response rate and occurrence of cancer-related *** rule mining(ARM)was used to investigate the associations among medicinal herbs and patient *** The fifty-four studies included in this analysis were comprised of RCTs(63.0%)and observational studies(37.0%).Most RCTs focused on hematological malignancies(41.2%).The study outcomes included chemotherapy-induced toxicities(76.5%),infection rate(35.3%),and response,survival or relapse rate(23.5%).The methodological quality of most of the RCTs(82.4%)and observational studies(80.0%)was r

关键词： Traditional Chinese Medicine Herbal medicine Pediatric oncology Data mining Associate rule mining Chemotherapy

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Surface wave inversion with unknown number of soil layers based on a hybrid learning procedure of deep learning and genetic algorithm

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 345-358页

作者： Zan Zhou Thomas Man-Hoi lok Wan-Huan Zhou Department of Civil and Environmental Engineering Faculty of Science and TechnologyUniversity of MacaoMacaoChina

Surface wave inversion is a key step in the application of surface waves to soil velocity ***,a common practice for the process of inversion is that the number of soil layers is assumed to be known before using heuristic search algorithms to compute the shear wave velocity profile or the number of soil layers is considered as an optimization ***,an improper selection of the number of layers may lead to an incorrect shear wave velocity *** this study,a deep learning and genetic algorithm hybrid learning procedure is proposed to perform the surface wave inversion without the need to assume the number of soil ***,a deep neural network is adapted to learn from a large number of synthetic dispersion curves for inferring the layer ***,the shear-wave velocity profile is determined by a genetic algorithm with the known layer *** applying this procedure to both simulated and real-world cases,the results indicate that the proposed method is reliable and efficient for surface wave inversion.

关键词： surface wave inversion analysis shear-wave velocity profile deep neural network genetic algorithm

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Spreadsheet quality assurance:a literature review

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Frontiers of Computer Science 2024年第2期18卷 61-82页

作者： Pak-lok POON Man Fai LAU Yuen Tak YU Sau-Fun TANG School of Engineering and Technology Central Queensland UniversityMelbourne 3000Australia Department of Computing Technologies Swinburne University of TechnologyHawthorn 3122Australia Department of Computer Science City University of Hong KongHong Kong SAR 999077China The Royal Victorian Eye and Ear Hospital East Melbourne 3002Australia

Spreadsheets are very common for information processing to support decision making by both professional developers and non-technical end ***,business intelligence and artificial intelligence are increasingly popular in the industry nowadays,where spreadsheets have been used as,or integrated into,intelligent or expert systems in various application ***,it has been repeatedly reported that faults often exist in operational spreadsheets,which could severely compromise the quality of conclusions and decisions based on the *** a view to systematically examining this problem via survey of existing work,we have conducted a comprehensive literature review on the quality issues and related techniques of spreadsheets over a 35.5-year period(from January 1987 to June 2022)for target journals and a 10.5-year period(from January 2012 to June 2022)for target *** other findings,two major ones are:(a)Spreadsheet quality is best addressed throughout the whole spreadsheet life cycle,rather than just focusing on a few specific stages of the life cycle.(b)Relatively more studies focus on spreadsheet testing and debugging(related to fault detection and removal)when compared with spreadsheet specification,modeling,and design(related to development).As prevention is better than cure,more research should be performed on the early stages of the spreadsheet life *** by our comprehensive review,we have identified the major research gaps as well as highlighted key research directions for future work in the area.

关键词： decision support system end-user computing end-user programming Excel spreadsheet

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A path planning algorithm for a crop monitoring fixed-wing unmanned aerial system

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Science China(Information Sciences) 2024年第8期67卷 5-23页

作者： Longhao QIAN Yi lok LO Hugh Hong-tao LIU Institute of Aerospace Studies University of Toronto Department of Mechanical Engineering The University of Hong Kong

With the growing demand for automation in agriculture, industries increasingly rely on drones to perform crop monitoring and surveillance. In this regard, fixed-wing unmanned aerial systems(UASs)are viable platforms for scanning a large crop field, given their payload capacity and range. To achieve maximum coverage without landing for battery replacement, an algorithm for producing a minimal required energy survey path is essential. Hence, an energy-aware coverage path planning algorithm is proposed *** constraints for a fixed-wing UAS to fly at low altitudes while achieving full coverage of the crop field are first analyzed. Then, the full path is decomposed into straight-line and U-turn primitives. Finally, an algorithm to calculate a combination of straight-line segments and U-turns is proposed to obtain the path with minimum required energy consumption. The genetic algorithm is used to efficiently determine the order of the straight-line paths to traverse. Case studies show that the proposed algorithm can produce planning results for a convex-polygon-shaped crop field.

关键词： aerial survey energy minimization fixed-wing UAS genetic algorithm path planning

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ATP-binding cassette transporters as possible targets for the intervention of neurodegenerative diseases

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Neural Regeneration Research 2024年第4期19卷 721-722页

作者： Hiu Chuen lok Glenda M.Halliday Woojin Scott Kim Brain and Mind Centre&School of Medical Sciences The University of SydneySydneyNSWAustralia

ATP-binding cassette(ABC)transporters are ubiquitous membrane-bound proteins that are responsible for the translocation of a broad spectrum of substrates across cellular membranes,including lipids,amino acids,nucleosides,sugars,and ***,ABC transporters are highly expressed in the *** their functions in the brain still need to be elucidated,several members are implicated in the pathogenesis of neurodegenerative diseases,including Alzheimer’s disease(AD),Parkinson’s disease(PD),and frontotemporal *** this perspective,we will review current knowledge of ABC transporters in the central nervous system in terms of physiological functions and pathology in ***,we will explore the possibilities of ABC transporters as potential targets in the development of therapeutics for neurodegenerative diseases.

关键词： sugar degenerative diseases

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FE65:a hub for neurodevelopment

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Neural Regeneration Research 2024年第9期19卷 1883-1884页

作者： Yuqi Zhai Laura lok-Haang Ng Dennis Dik-Long Chau Kwok-Fai Lau School of Life Sciences Faculty of ScienceThe Chinese University of Hong KongHong Kong Special Administrative RegionChina

FE65,initially identified as a binding partner of amyloid precursor protein(APP),is an adaptor protein enriched in the brain and regulated during ***65 belongs to the FE65 protein *** family is comprised of three memb... 详细信息

关键词： family development partner

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Exploiting fly models to investigate rare human neurological disorders

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Neural Regeneration Research 2025年第1期20卷 21-28页

作者： Tomomi Tanaka Hyung-lok Chung Department of Neurology Houston Methodist Research InstituteHoustonTXUSA Department of Neurology Weill Cornell Medical CollegeNew YorkNYUSA

Rare neurological diseases,while individually are rare,collectively impact millions globally,leading to diverse and often severe neurological *** attributed to genetic mutations that disrupt protein function or structure,understanding their genetic basis is crucial for accurate diagnosis and targeted *** investigate the underlying pathogenesis of these conditions,researchers often use non-mammalian model organisms,such as Drosophila(fruit flies),which is valued for their genetic manipulability,cost-efficiency,and preservation of genes and biological functions across evolutionary *** tools available in Drosophila,including CRISPR-Cas9,offer a means to manipulate gene expression,allowing for a deep exploration of the genetic underpinnings of rare neurological *** boasts a versatile genetic toolkit,rapid generation turnover,and ease of large-scale experimentation,making it an invaluable resource for identifying potential drug *** can expose flies carrying disease-associated mutations to various compounds,rapidly pinpointing promising therapeutic agents for further investigation in mammalian models and,ultimately,clinical *** this comprehensive review,we explore rare neurological diseases where fly research has significantly contributed to our understanding of their genetic basis,pathophysiology,and potential therapeutic *** discuss rare diseases associated with both neuron-expressed and glial-expressed *** cases include mutations in CDK19 resulting in epilepsy and developmental delay,mutations in TIAM1 leading to a neurodevelopmental disorder with seizures and language delay,and mutations in IRF2BPL causing seizures,a neurodevelopmental disorder with regression,loss of speech,and abnormal *** we explore mutations in EMC1 related to cerebellar atrophy,visual impairment,psychomotor retardation,and gain-of-function mutations in ACOX1 causing Mitchell ***-of-fun

关键词： ACOX1 Drosophila melanogaster glia lipid metabolism model organisms neuroinflammation neurologic disorders neuron rare disease VLCFA

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ChatLib:重构智慧图书馆知识服务平台

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大学图书馆学报 2024年第2期42卷 72-80页

作者：袁虎声唐嘉乐赵洗尘杨泓睿澳门科技大学资讯科技发展办公室中国澳门999078 澳门科技大学校长办公室中国澳门999078 澳门科技大学图书馆中国澳门999078

探索和理解基于ChatGPT的知识服务新业态,研究重构智慧图书馆知识服务体系,为图书馆数智转型提供新思路、新方案、新平台。基于生成式人工智能技术,搭建由智能交互层、知识服务层和知识引擎层组成的会话式知识服务平台——ChatLib,构建... 详细信息

探索和理解基于ChatGPT的知识服务新业态,研究重构智慧图书馆知识服务体系,为图书馆数智转型提供新思路、新方案、新平台。基于生成式人工智能技术,搭建由智能交互层、知识服务层和知识引擎层组成的会话式知识服务平台——ChatLib,构建起包括向量化知识组织、会话式知识发现、启发式知识推荐、辩证式细粒度阅读的会话式知识服务体系。ChatLib以其创新性的方法改变了知识理解、知识组织和知识获取方式,提供了更为便捷、准确、个性化的知识服务,深化了图书馆的服务价值和服务能力。目前,ChatLib已在澳门科技大学投入应用,其服务正在持续优化和延伸中。

关键词： ChatGPT 大语言模型智慧图书馆知识管理知识服务

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香港中学文凭考试等级预测研究

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中国考试 2024年第2期 33-39+101页

作者：许嘉凌萧伟乐席小明香港考试及评核局

为研究香港中学文凭考试（简称文凭试）等级预测结果，以过往文凭试结果作为依据，通过标准化程序，对2020—2023年共计146 180名考生根据其校内评核成绩进行文凭试等级预测；并采用问卷调查法，基于各参与学校组织架构、教师的工作经... 详细信息

为研究香港中学文凭考试（简称文凭试）等级预测结果，以过往文凭试结果作为依据，通过标准化程序，对2020—2023年共计146 180名考生根据其校内评核成绩进行文凭试等级预测；并采用问卷调查法，基于各参与学校组织架构、教师的工作经验、公开考试阅卷经验及专业发展活动等，运用多层线性模型探讨学校属性与校内评核的关系。结果显示：中文、英文、数学、通识教育4门核心科目等级预测结果具有较高的准确度，其中英文预测结果最佳，其余3科预测结果类似；选修科目则因每年选考人数少导致文凭试成绩变化大，进而影响预测结果；多层线性模型分析显示，不同学校属性对于不同科目的校内评核具有不同的预测效果。

关键词：香港中学文凭考试等级预测校内评核标准参照测验

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香港特别行政区视障读者服务创新探究——以香港城市大学邵逸夫图书馆高等融合教育支持服务为例

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国家图书馆学刊 2024年第2期33卷 74-82页

作者：景祥祜王玮乐肖寒月香港城市大学邵逸夫图书馆中国香港城市大学中国

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中... 详细信息

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中《西屿塔灯历险》案例具体展示了两阶段服务学习的开展方式,探究图书馆在高等融合教育支持服务体系下的视障读者服务创新。图3。表1。参考文献22。

关键词：高等融合教育服务学习视障读者高等教育信息素养框架

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