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Al和Cr协同作用提高核用高强钢耐水蒸气氧化性能

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金属学报 2024年第3期60卷 357-366页

作者：彭祥阳张乐李聪聪侯硕刘迪周建明路广遥蒋虽合中广核研究院有限公司设备研究所深圳518000 北京科技大学新金属材料国家重点实验室北京100083

前期研发的Fe-Ni-Al基超高强度马氏体时效钢表现出了良好的力学和抗辐照性能,然而典型Cr_(2)O_(3)氧化保护膜的耐热钢在轻水反应堆高温高压含水蒸气的服役环境中极易失效,亟待研发兼具抗高温水蒸气氧化、优异力学和抗辐照性能的先进材... 详细信息

前期研发的Fe-Ni-Al基超高强度马氏体时效钢表现出了良好的力学和抗辐照性能,然而典型Cr_(2)O_(3)氧化保护膜的耐热钢在轻水反应堆高温高压含水蒸气的服役环境中极易失效,亟待研发兼具抗高温水蒸气氧化、优异力学和抗辐照性能的先进材料。本工作在前期研发的Fe-Ni-Al系超高强度马氏体时效钢基础上添加不同含量的Cr元素,在保持新型马氏体钢优异力学性能的同时,对其在干燥空气和含水蒸气环境中的氧化性能进行研究。采用非自耗真空电弧炉制备合金铸锭,并对时效处理后的高强钢进行600℃干燥空气和潮湿空气2种环境中的抗氧化性能测试,对氧化后样品的表面和截面形貌进行微观组织表征。结果表明,添加9%Cr后的Fe-13Ni-2.3Al高强钢在600℃空气+10%水蒸气的气氛中氧化100 h的平均单位面积增重仅为0.1 mg/cm^(2),是添加5%Cr的Fe-13Ni-2.3Al高强钢和Fe-18Ni-3Al马氏体时效钢的1/50。对氧化后高强钢微观组织表征分析表明,在Al和Cr元素协同作用下,Fe-13Ni-9Cr-2.3Al高强钢在600℃空气+10%水蒸气条件下表面自发形成了富Fe、Cr、Al的复合氧化膜,提高了抗高温水蒸气氧化性能,其中Cr通过第三组元效应降低氧化物膜-基体界面氧分压,从而促进在高温水蒸气条件下在基体表面形成致密连续的富Al氧化膜。

关键词：超高强度钢水蒸气氧化氧化膜第三组元效应协同效应

不同强度DENBA+电场辅助处理冻结草莓后对其解冻品质影响的比较

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现代食品科技 2024年第2期40卷 160-167页

作者：张鑫华殷睿郝义李斌于居盟杨娜姜晗孙希云沈阳农业大学食品学院辽宁沈阳110866 辽宁省果树科学研究所辽宁营口115009 辽宁营口东盛实业有限公司辽宁营口115000

DENBA+技术可利用高压静电,通过共振食品细胞中的水分子使其更为活性化,达到保持营养成分完整、延迟氧化、实现食材保鲜的目的,可与食品速冻保鲜配合使用。为系统地考察外加DENBA+静电场对冻藏草莓超声解冻后品质的影响,该实验以丹东九... 详细信息

DENBA+技术可利用高压静电,通过共振食品细胞中的水分子使其更为活性化,达到保持营养成分完整、延迟氧化、实现食材保鲜的目的,可与食品速冻保鲜配合使用。为系统地考察外加DENBA+静电场对冻藏草莓超声解冻后品质的影响,该实验以丹东九九草莓作为研究对象,通过对比分析感官评价、色差、硬度、汁液流失率、可溶性固形物、总糖、总酚等7项指标,探究草莓在外加不同强度DENBA+静电场条件下冻结对其解冻品质的影响。实验结果表明,经外加高低电场辅助草莓冻结解冻品质均优于空白对照组,且与2000 V高强度DENBA+电场辅助冻结相比,经外加500 V低强度DENBA+电场辅助冻结后,感官评价综合分数最高,色差下降1.70%,硬度提高22.45%,汁液流失率下降27.72%;可溶性固形物含量提高8.16%、总糖含量提高4.79%、总酚含量提高9.90%,上述各项指标低电场辅助处理较高电场辅助处理效果更优且差异显著(P<0.05),其解冻特性呈现相对较好的状态,综合分析得出500V的低电场辅助冻藏草莓的品质较优。

关键词： DENBA+静电场草莓冻藏超声解冻品质

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Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study

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World Journal of Hepatology 2024年第5期16卷 809-821页

作者： Yuan-Yao Zhang Sen Luo Hai Li Shu-Ning Sun Xian-Bo Wang Xin Zheng Yan Huang Bei-Ling Li Yan-Hang Gao Zhi-Ping Qian Feng liu Xiao-Bo Lu Jun-Ping liu Hao-Tang Ren Yu-Bao Zheng Hua-Dong Yan Guo-Hong Deng Liang Qiao Yan Zhang Wen-Yi Gu Xiao-Mei Xiang Yi Zhou Yi-Xin Hou Qun Zhang Yan Xiong Cong-Cong Zou Jun Chen Ze-Bing Huang Xiu-Hua jiang Ting-Ting Qi Yuan-Yuan Chen Na Gao Chun-Yan liu Wei Yuan Xue Mei Jing Li Tao Li Rong-Jiong Zheng Xin-Yi Zhou Jun Zhao Zhong-Ji Meng Department of Infectious Disease Institute of Biomedical ResearchRegulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key LaboratoryHubei provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver CancerTaihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200120China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400000China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100020China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430020Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 110051Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 200093China Tianjin Institute of Hepatology Nankai University Second People's HospitalTianjin 300192China Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054Xinjiang Uygur Autonomous RegionChina Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Infectious Diseases The Thir

BACKGROUND Acute-on-chronic liver disease(AoCLD)accounts for the majority of patients hospitalized in the Department of Hepatology or Infectious *** To explore the characterization of AoCLD to provide theoretical guidance for the accurate diagnosis and prognosis of *** Patients with AoCLD from the Chinese Acute-on-Chronic Liver Failure(ACLF)study cohort were included in this *** clinical characteristics and outcomes,and the 90-d survival rate associated with each clinical type of AoCLD were analyzed,using the Kaplan-Meier method and the log-rank *** A total of 3375 patients with AoCLD were enrolled,including 1679(49.7%)patients with liver cirrhosis acute decompensation(LC-AD),850(25.2%)patients with ACLF,577(17.1%)patients with chronic hepatitis acute exacer-bation(CHAE),and 269(8.0%)patients with liver cirrhosis active phase(LC-A).The most common cause of chronic liver disease(CLD)was HBV infection(71.4%).The most common precipitants of AoCLD was bacterial infection(22.8%).The 90-d mortality rates of each clinical subtype of AoCLD were 43.4%(232/535)for type-C ACLF,36.0%(36/100)for type-B ACLF,27.0%(58/215)for type-A ACLF,9.0%(151/1679)for LC-AD,3.0%(8/269)for LC-A,and 1.2%(7/577)for *** HBV infection is the main cause of CLD,and bacterial infection is the main precipitant of *** most common clinical type of AoCLD is *** diagnosis and timely intervention are needed to reduce the mortality of patients with LC-AD or ACLF.

关键词： Acute-on-chronic liver disease Acute-on-chronic liver failure Liver cirrhosis Clinical features Prognosis

Numerical simulation study on the relationship between mining heights and shield resistance in longwall panel

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International Journal of Mining Science and Technology 2017年第2期27卷 293-297页

作者： liu Chuang Li Huamin jiang Dongjie School of Energy Science and Engineering Henan Polytechnic University School of Safety Science and Engineering Henan Institute of Engineering

A numerical model based on a Continuum-based Distinct Element Method(CDEM) was used to carry out a dynamic simulation of the interaction between shield and rock strata movement in longwall mining. In Northern China, the Ordos coal field geological conditions and operational characteristics were used as a case example. The CDEM was constructed on Ordos coal field shield's operation characteristics and geological conditions. Numerical modelling was carried out to investigate the effects of different mining heights on the caving process, movement characteristics, equilibrium and stability conditions of overburden as the interaction between shield and surrounding rocks. With the numerical model, the internal factors for changes in shield resistance under different mining heights was found. The quantitative relationship between mining heights and shield resistance was also obtained by the numerical simulation.

关键词： Numerical simulation Shield resistance Interaction between shield and surrounding rock Mining heights

加味苇茎汤治疗支气管扩张症稳定期(痰热蕴肺证)的系列单病例随机对照研究

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中药新药与临床药理 2024年第6期35卷 878-883页

作者：刘城鑫赵泽铤梁慧秋刘晓芳黄秀芳刘小虹詹少锋黄慧婷江勇深圳市中西医结合医院广东深圳518104 广州中医药大学第一临床医学院广东广州510405 广州中医药大学第一附属医院广东广州510405

目的评价加味苇茎汤治疗支气管扩张症稳定期(痰热蕴肺证)的临床疗效和安全性。方法运用系列单病例随机对照试验(N-of-1试验)的方法,选取诊断为支气管扩张症稳定期,辨证属于痰热蕴肺证的患者,在一个治疗周期内先后接受两种不同的治疗方案... 详细信息

目的评价加味苇茎汤治疗支气管扩张症稳定期(痰热蕴肺证)的临床疗效和安全性。方法运用系列单病例随机对照试验(N-of-1试验)的方法,选取诊断为支气管扩张症稳定期,辨证属于痰热蕴肺证的患者,在一个治疗周期内先后接受两种不同的治疗方案,试验期治疗用加味苇茎汤,对照期治疗用西药氨溴索片,期间设置洗脱期,试验期和对照期的用药先后顺序按随机化方式决定,以目测模拟尺测量法(visual analogue scales,VAS法)评价治疗前后的症状改变,记录24 h痰量和自我评估测试(COPD Assessment Test,CAT)评分,并观察研究期间的不良反应。采用SPSS 25.0、GraphPad Prism 8软件进行统计分析和绘图,入组前的组间差异比较采用独立样本t检验分析;试验期和对照期治疗前后的症状得分、24 h痰量和CAT评分对比,以及两组治疗前后的差值对比采用配对t检验,比较临床差异和统计学差异。结果共有9例患者入组,最终纳入分析的治疗轮次为16次。试验期治疗后中医证候总积分,咳嗽、咳痰、痰液颜色、胸闷胸痛、口苦口干、乏力疲倦等症状,24 h痰量和CAT评分较治疗前改善,差异均具有统计学意义(P<0.05)。试验期和对照期中医证候总积分、痰液颜色评分、胸闷胸痛评分和24 h痰量治疗前后差值比较,试验组较对照组改善明显,差异有统计学意义(P<0.05)。观察期间未出现与试验方法或药物有关的不良事件。结论加味苇茎汤能综合改善支气管扩张症稳定期患者的临床症状,总体疗效优于西药氨溴索,且安全性良好。

关键词：支气管扩张症稳定期痰热蕴肺证加味苇茎汤单病例随机对照试验

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爪型符号模式矩阵要求代数正的相关研究

白城师范学院学报 2024年第2期38卷 10-16页

作者：田岩焦旸殷明娥蒋思源辽宁师范大学数学学院辽宁大连116029

基于爪形符号模式矩阵的结构特点,研究了爪型符号模式矩阵是否要求代数正.利用图论和组合矩阵论的知识,证明了爪型符号模式矩阵要求代数正的必要条件.同时,分别给出了阶数小于5的爪型符号模式矩阵要求代数正的等价条件.研究结论丰富了... 详细信息

基于爪形符号模式矩阵的结构特点,研究了爪型符号模式矩阵是否要求代数正.利用图论和组合矩阵论的知识,证明了爪型符号模式矩阵要求代数正的必要条件.同时,分别给出了阶数小于5的爪型符号模式矩阵要求代数正的等价条件.研究结论丰富了组合矩阵理论,为符号模式矩阵允许代数正和要求代数正的研究提供了方法和思路.

关键词：符号模式矩阵代数正要求代数正爪型符号模式矩阵

巴利昔单抗短期替代钙调蛋白抑制剂预防急性移植物抗宿主病的探索性研究

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中华血液学杂志 2024年第2期45卷 115-120页

作者：邵珊刘慧霞蒋瑛李肃魏道林朱骏王椿赵初娴上海闸新中西医结合医院骨髓移植科上海200040

目的探讨在钙调蛋白抑制剂(CNI)不耐受患者中短期应用重组抗CD25人源化单克隆抗体巴利昔单抗(Basiliximab)单药预防异基因造血干细胞移植(allo-HSCT)后急性移植物抗宿主病(GVHD)的有效性。方法本研究纳入2021年8月至2022年8月在上海闸... 详细信息

目的探讨在钙调蛋白抑制剂(CNI)不耐受患者中短期应用重组抗CD25人源化单克隆抗体巴利昔单抗(Basiliximab)单药预防异基因造血干细胞移植(allo-HSCT)后急性移植物抗宿主病(GVHD)的有效性。方法本研究纳入2021年8月至2022年8月在上海闸新中西医结合医院骨髓移植科行挽救性allo-HSCT后因CNI严重不良反应而应用巴利昔单抗预防急性GVHD的17例难治性恶性血液病患者。男7例,女10例,中位年龄43(18~67)岁。停用CNI后,给予巴利昔单抗1 mg/kg每周1次进行替代预防,直至患者有条件重新启用CNI或哺乳动物雷帕霉素靶体蛋白(mTOR)抑制剂。结果巴利昔单抗的替代预防中位开始时间为移植后5(1~32)d,替代治疗中位持续时间为20(7~120)d。所有患者均获得粒细胞植入,中位植入时间12(10~17)d。13例患者获得血小板植入,中位植入时间13(11~20)d。8例(47.1%)患者发生Ⅱ~Ⅳ度急性GVHD,4例(23.6%)发生Ⅲ/Ⅳ度急性GVHD。仅有1例患者死于急性GVHD。至随访截止,17例患者中7例死亡,存活患者中随访最长时间为347 d,中位生存时间未达到,移植后6个月总生存率为62.6%。17例患者中,13例(76.4%)发生巨细胞病毒再激活,7例(41.2%)发生EB病毒激活,未发生巨细胞病毒病。结论在allo-HSCT过程中出现CNI不耐受时,短期单药应用巴利昔单抗可作为急性GVHD的替代预防方案。

关键词：重组抗CD25人源化单克隆抗体异基因造血干细胞移植钙调蛋白抑制剂移植物抗宿主病

Magnetically rotational reactor for absorbing benzene emissions by ionic liquids

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China Particuology 2007年第1期5卷 130-133页

作者： Yangyang jiang Chen Guo Huizhou liu Laboratory of Separation Science and Engineering National Key Laboratory of Biochemical Engineering Institute of Process Engineering Chinese Academy of Sciences Beijing 100080 China Graduate University of Chinese Academy of Sciences Beijing 100080 China

A magnetically rotational reactor （MRR） has been developed and used in absorbing benzene emissions. The MRR has a permanent magnet core and uses magnetic ionic liquid [bmim]FeCl4 as absorbent. Benzene emissions were carried by N2 into the MRR and were absorbed by the magnetic ionic liquid. The rotation of the permanent magnet core provided impetus for the agitation of the magnetic ionic liquid, enhancing mass transfer and making benzene better dispersed in the absorbent. 0.68 g benzene emissions could be absorbed by a gram of [bmim]FeCl4, 0.27 and 0.40 g/g higher than that by [bmim]PF6 and [bmim]BF4, respectively. The absorption rate increased with increasing rotation rate of the permanent magnet.

关键词： Magnetically rotational reactor (MRR) Magnetic ionic liquid Absorption Permanent magnet

Integrated multi-item packaging and vehicle routing with split delivery problem for fresh agri-product emergency supply at large-scale epidemic disease context

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第2期8卷 196-208页

作者： Yiping jiang Bei Bian Yang liu College of Information Management Nanjing Agricultural UniversityNanjing 210095China College of Artificial Intelligence Nanjing Agricultural UniversityNanjing 210095China

Fresh agri-product emergency supply is crucial to secure the basic livelihood of residents at large-scale epidemic disease context. Considering the massive demand and limited transportation resources, this study integrates multi-item packaging and vehicle routing with split delivery to improve the emergency supply capacity. Firstly, three specific objectives of fresh agri-product emergency supply at large-scale epidemic disease context are formulated, i.e., average response time, infectious risk possibility and transportation resource utilization. Then, a multi-item packaging strategy is proposed to consolidate different categories of fresh agri-products according to the food cold chain *** optimization model integrating multi-item packaging and vehicle routing with split delivery is developed to jointly decide the optimal packaging scheduling, vehicle assignment and delivery routing. Next, an improved genetic algorithm based on solution features (IGA-SF) is designed to solve the integrated model with multiple decision variables. Finally,a case on fresh agri-product emergency supply of Huangpi District, Wuhan in the context of the Corona Virus Disease 2019(COVID-19) is carried out to illustrate the efficiency and feasibility of the proposed model. The numerical results of medium-to-largescale cases demonstrate that the proposed IGA-SF could save 23.91% CPU time and 37.80% iteration number on average than genetic algorithm. This study could satisfy different emergency scenario requirements flexibly, and provide scientific decision support for provincial and national governments on fresh agri-product emergency supply.

关键词： Transportation engineering Fresh agri-product emergency supply Multi-item packaging Vehicle routing with split delivery Corona virus disease 2019(COVID-19)