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Universal paradigm of ternary metacomposites with tunable epsilon-negative and epsilon-near-zero response for perfect electromagnetic shielding

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Rare Metals 2024年第2期43卷 796-809页

作者： Yun-Peng Qu Yun-Lei Zhou Yang Luo Yao liu Jun-Fei Ding Yan-Li Chen xiu Gong Jing-Liang Yang Qiong Peng Xiao-Si Qi College of Physics Guizhou UniversityGuiyang550025China Hangzhou Institute of Technology Xidian UniversityHangzhou311231China Department of Materials ETH Zurich8093ZurichSwitzerland Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan250061China

CaCu_(3)Ti_(4)O_(12)(CCTO)ceramic nanocomposites incorporating graphene–carbon black(GRCB)fillers were fabricated by spark plasma sintering *** percolative effects of conductive GRCB fillers on dielectric response of GRCB/CCTO ternary metacomposites were systematically *** weakly real permittivity(ε′)-negative response(ε′~−1×10^(2))was achieved which originated from weakly low-frequency plasmonic state of free carriers within constructed GRCB *** enhancing three-dimensional GRCB network,the plasma frequency of metacomposites increased while the damping factor ***,theε′-negative values of metacomposites were tuned from−10^(2) to−10^(4) orders of magnitude andε′-near-zero(ENZ)frequencies from~142 to~340 MHz which substantially benefited from the moderate carrier concentration of GRCB dual *** Drude model and equivalent circuit models were adopted to demonstrate dielectric and electrical *** obtained metacomposites show strong EM shielding effect along with enhanced plasmonic oscillation and even better achieving perfect EM shielding effect in ENZ *** work achieves the tunableε′-negative andε′-near-zero response and more importantly clarifies its regulation mechanism in ceramic-based ternary metacomposites,which opens up the possibility of designing high-performance EM shielding materials based on metacomposites.

关键词： Metacomposites Ceramic matrix composites Negative permittivity Epsilon-near-zero Electromagnetic shielding

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Reactive transport modeling constraints on the complex genesis of a lacustrine dolomite reservoir: A case from the Eocene Qaidam Basin,China

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Petroleum Science 2024年第4期21卷 2240-2256页

作者： Ying Xiong Bo liu xiu-Cheng Tan Zheng-Meng Hou Jia-Shun Luo Ya-Chen Xie Kai-Bo Shi Kun-Yu Wu School of Earth and Space Sciences Peking University Institute of Oil and Gas Peking University China National Petroleum Corporation Key Laboratory of Carbonate Reservoirs Southwest Petroleum University Institute of Subsurface Energy Systems Clausthal University of Technology Research Institute of Exploration and Development PetroChina Qinghai Oil Field Company

Reactive transport modeling(RTM) is an emerging method used to address geological issues in diagenesis research. However, the extrapolation of RTM results to practical reservoir prediction is not sufficiently understood. This paper presents a case study of the Eocene Qaidam Basin that combines RTM results with petrological and mineralogical evidence. The results show that the Eocene Xiaganchaigou Formation is characterized by mixed siliciclastic-carbonate-evaporite sedimentation in a semiclosed saline lacustrine environment. Periodic evaporation and salinization processes during the syngeneticpenecontemporaneous stage gave rise to the replacive genesis of dolomites and the cyclic enrichment of dolomite in the middle-upper parts of the meter-scale depositional sequences. The successive change in mineral paragenesis from terrigenous clastics to carbonates to evaporites was reconstructed using RTM simulations. Parametric uncertainty analyses further suggest that the evaporation intensity(brine salinity) and particle size of sediments(reactive surface area) were important rate-determining factors in the dolomitization, as shown by the relatively higher reaction rates under conditions of higher brine salinity and fine-grained sediments. Combining the simulation results with measured mineralogical and reservoir physical property data indicates that the preservation of original intergranular pores and the generation of porosity via replacive dolomitization were the major formation mechanisms of the distinctive lacustrine dolomite reservoirs(widespread submicron intercrystalline micropores) in the Eocene Qaidam Basin. The results confirm that RTM can be effectively used in geological studies, can provide a better general understanding of the dolomitizing fluid-rock interactions, and can shed light on the spatiotemporal evolution of mineralogy and porosity during dolomitization and the formation of lacustrine dolomite reservoirs.

关键词： Reactive transport modeling Lacustrine dolomite Mineralogy and porosity evolution Reservoir genesis

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Global dust density in two-dimensional complex plasma

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Chinese Physics B 2024年第6期33卷 445-450页

作者：赵逸真刘松芬孔伟杨芳 School of Physics Nankai UniversityTianjin 300071China College of Science Civil Aviation University of ChinaTianjin 300300China

The driven-dissipative Langevin dynamics simulation is used to produce a two-dimensional(2D) dense cloud, which is composed of charged dust particles trapped in a quadratic potential. A 2D mesh grid is built to analyze the center-to-wall dust density. It is found that the local dust density in the outer region relative to that of the inner region is more nonuniform,being consistent with the feature of quadratic potential. The dependences of the global dust density on equilibrium temperature, particle size, confinement strength, and confinement shape are investigated. It is found that the particle size, the confinement strength, and the confinement shape strongly affect the global dust density, while the equilibrium temperature plays a minor effect on it. In the direction where there is a stronger confinement, the dust density gradient is bigger.

关键词： dust particles quadratic potential two-dimensional mesh grid

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施用腐植酸复合肥对小麦抗旱防衰能力的影响及其机理

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中国生态农业学报 2006年第1期14卷 139-141页

作者：薛世川刘秀芬邓景华河北农业大学资源与环境学院保定071001 廊坊师范学院廊坊102800 保定市委农工部保定071000

试验研究施用腐植酸复合肥对小麦抗旱、防衰能力的影响结果表明，腐植酸浓度为25～50mg／L时对小麦根系伸展与活力的促进作用最强，根内超氧化物歧化酶、过氧化物酶和硝酸还原酶活性最高，麦苗长势最佳且生物量最大。土培条件下腐植酸... 详细信息

试验研究施用腐植酸复合肥对小麦抗旱、防衰能力的影响结果表明，腐植酸浓度为25～50mg／L时对小麦根系伸展与活力的促进作用最强，根内超氧化物歧化酶、过氧化物酶和硝酸还原酶活性最高，麦苗长势最佳且生物量最大。土培条件下腐植酸复合肥比等养分量化肥更显著提高小麦体内超氧化物歧化酶活性与脯氨酸含量，降低质膜透性，有效提高小麦抗旱与防衰能力，增加干物质量累积。施肥量与各生理指标间呈二次曲线相关，峰值施肥量为2．9～4．3g／盆。

关键词：腐植酸复合肥小麦抗旱防衰机理

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Advance in reversible Zn anodes promoted by 2D materials

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Rare Metals 2024年第4期43卷 1350-1369页

作者： Shu-Yuan Lei Jin-xiu feng Yu-Chao Chen Dong Zheng Wen-Xian liu Wen-Hui Shi Fang-Fang Wu Xie-Hong Cao School of Materials Science and Engineering Zhejiang University of TechnologyHangzhou310014China Center for Membrane Separation and Water Science and Technology College of Chemical EngineeringZhejiang University of TechnologyHangzhou310014China

With the growing energy demand associated with high safety and low-cost requirement,aqueous zinc-ion batteries(AZIBs)have been considered as one of the most promising next-generation ***,some key issues,such as uncontrollable dendrites growth,severe corrosion,hydrogen evolution and side reactions of Zn anodes during charge/discharge process,have hindered its pragmatic ***-dimensional(2D)materials hold advantages of unique physical and chemical properties,large surface areas and abundant active sites,which have been successfully used to overcome the above shortcomings of Zn anodes in recent *** this review,the issues and challenges of Zn anodes are ***,the state-of-the-art progress on Zn anodes modification based on 2D materials such as graphene,2D metal carbides and nitrides(MXenes),2D metal-organic frameworks(MOFs),2D covalent organic frameworks(COFs),2D transition metal compounds and other 2D materials is discussed in ***,the perspectives of employing 2D materials in highly reversible Zn anodes are summarized and discussed.

关键词： 2D materials Aqueous zinc-ion battery Zn anodes Dendrites growth

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Crosstalk among Oxidative Stress,Autophagy,and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells:A Mixed Computational and Experimental Study

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Current Medical Science 2024年第3期44卷 578-588页

作者： Yi-miao LUO Shu-sen liu Ming ZHAO Wei WEI Jiu-xiu YAO Jia-hui SUN Yu CAO Hao LI Department of Geriatrics Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan)Beijing100901China Department of Integration of Chinese and Western Medicine Peking University Health Science CenterBeijing100191China School of Pharmacy Harbin University of CommerceHarbin150028China Xiyuan Hospital China Academy of Chinese Medical ScienceBeijing100901China Wangjing Hospital China Academy of Chinese Medical ScienceBeijing100102China

Objective Brain microvascular endothelial cells (BMECs) were found to shift from their usually inactive state to an active state in ischemic stroke (IS) and cause neuronal damage. Ginsenoside Rb1 (GRb1),a component derived from medicinal plants,is known for its pharmacological benefits in IS,but its protective effects on BMECs have yet to be explored. This study aimed to investigate the potential protective effects of GRb1 on BMECs. Methods An in vitro oxygen-glucose deprivation/reperfusion (OGD/R) model was established to mimic ischemia-reperfusion (I/R) injury. Bulk RNA-sequencing data were analyzed by using the Human Autophagy Database and various bioinformatic tools,including gene set enrichment analysis (GSEA),Gene Ontology (GO) classification and enrichment analysis,Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis,protein-protein interaction network analysis,and molecular docking. Experimental validation was also performed to ensure the reliability of our findings. Results Rb1 had a protective effect on BMECs subjected to OGD/R injury. Specifically,GRb1 was found to modulate the interplay between oxidative stress,apoptosis,and autophagy in BMECs. Key targets such as sequestosome 1 (SQSTM1/p62),autophagy related 5 (ATG5),and hypoxia-inducible factor 1-alpha (HIF-1α) were identified,highlighting their potential roles in mediating the protective effects of GRb1 against IS-induced damage. Conclusion GRbl protects BMECs against OGD/R injury by influencing oxidative stress,apoptosis,and autophagy. The identification of SQSTM1/p62,ATG5,and HIF-1α as promising targets further supports the potential of GRb1 as a therapeutic agent for IS,providing a foundation for future research into its mechanisms and applications in IS treatment.

关键词： ischemic stroke ginsenoside Rb1 brain microvascular endothelial cells oxidative stress autophagy apoptosis bioinformatic analysis

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Schistosoma infection,KRAS mutation status,and prognosis of colorectal cancer

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Chinese Medical Journal 2024年第2期137卷 235-237页

作者： Xinyi Li Hongli liu Bo Huang Ming Yang Jun Fan Jiwei Zhang Mixia Weng Zhecheng Yan Li liu Kailin Cai xiu Nie Xiaona Chang Department of Pathology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Cancer Center Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Hubei Key Laboratory of Precision Radiation Oncology WuhanHubei 430022China Institute of Radiation Oncology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Epidemiology and Biostatistics The Ministry of Education Key Lab of Environment and HealthSchool of Public HealthHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China

To the Editor:Colorectal cancer(CRC)is a major cause of cancer-related death worldwide,and several pathogens with carcinogenic potential,such as Schistosoma,have been associated with an increased risk of *** a frequently mutated gene in CRC patients,kirsten rat sarcoma viral oncogene homolog(KRAS)helps to determine the selection of CRC ***,we aimed to elucidate the association among Schistosoma infection,KRAS mutation status,and the prognosis of CRC in this study.

关键词： Schistosoma KRAS prognosis

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中西药并针灸、推拿对椎动脉型颈椎病患者症状和血液流变学及脑血流参数的影响

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中国临床康复 2006年第15期10卷 26-28页

作者：袁曙光赵成文邢潇刘秀芬河北省人民医院中医科河北省石家庄市050071 河北省人民医院针灸按摩科河北省石家庄市050071

目的:观察中西药+针灸、推拿综合治疗方法对椎动脉型颈椎病患者临床症状、血液流变学及脑血流参数的影响,并与单纯应用药物或针灸推拿方法治疗结果进行对比。方法:①选择2002-05/2005-06河北省人民医院中医科、针灸按摩科就诊的椎动脉... 详细信息

目的:观察中西药+针灸、推拿综合治疗方法对椎动脉型颈椎病患者临床症状、血液流变学及脑血流参数的影响,并与单纯应用药物或针灸推拿方法治疗结果进行对比。方法:①选择2002-05/2005-06河北省人民医院中医科、针灸按摩科就诊的椎动脉型颈椎病患者160例,男95例,女65例。30～40岁26例,41～50岁65例,51～60岁49例,61岁以上者20例。按随机数字表法将患者分为3组:综合治疗组60例;药物治疗组50例;针灸推拿组50例。均对治疗方案及检测指标知情同意。②综合治疗组:采用口服中药、静脉滴注灯盏细辛注射液及针灸、推拿结合治疗。中药内服以补肾活血通痹汤加减。药物组成:骨碎补15g,威灵仙10g,泽泻30g,白术10g,川芎10g,丹参15g,姜黄10g,葛根20g等。药物均由本院中药房提供。每日1剂水煎服。静脉滴注灯盏细辛注射液40mL(云南生物谷灯盏花药业生产,批准文号:国药准字Z53021569,10mL/支),1次/d。推拿:患者取坐位,先在患者颈项部涂敷颈康膏(主要成分为补骨脂、狗脊,自制),用掌根揉搓颈椎皮肤后,再以揉、滚、搓、拿等手法放松颈背部项韧带、斜方肌、胸锁乳突肌及上肢肌肉。再行弹拨、理筋、点按等手法沿肌肉走向进行重点治疗,拨正偏歪的颈椎棘突,纠正椎体小关节错位;最后分别按揉风池穴、夹脊穴、百会穴等。针灸:用4.0～6.7cm毫针取第2～7颈椎夹脊穴、大椎、风池、百会、落枕穴,用平补平泻法,留针15～20min,中间行针一两次,1次/d。药物治疗组:采用口服补肾活血通痹汤加减,静点灯盏细辛注射液,方法同综合治疗组。针灸推拿组:选穴及方法同综合治疗组的针灸、推拿方法。各组均治疗20d。③所有患者治疗前后采用联邦德国EMETC-2021型经颅彩色多普勒超声诊断仪检测左右侧椎动脉和基底动脉血流参数,采用LG-R80A型血液流变学分析仪检测血液流变学参数。治疗20d后行主要症状评分[显著有效:主要症状消失,能参加正常劳动和工作(积分=0);有效:主要症状明显改善(积分较治疗前减少2分以上);无效:主要症状无变化(积分较治疗前减少不足2分者)]。④计量和计数资料差异比较采用t检验和χ2检验。结果:椎动脉型颈椎病患者160例均进入结果分析。①总有效率:综合治疗组明显高于药物治疗组和针灸推拿组(P<0.01,0.05)。②全血黏度、血浆黏度、红细胞聚集指数:3组治疗后明显低于治疗前(P<0.05～0.01),综合治疗组治疗后明显低于针灸推拿组(P<0.05),综合治疗组治疗后与药物治疗组相近。③左右侧椎动脉和基底动脉收缩期峰流速、舒张期末峰流速、平均峰流速:综合治疗组和针灸推拿组治疗后明显快于治疗前(P<0.05～0.01),综合治疗组治疗后明显快于其他2组治疗后(P<0.05～0.01)。结论:综合治疗法治疗椎动脉型颈椎病可通过改善血液流变学参数和椎动脉血液供应,明显改善患者症状,治疗效果优于单纯药物治疗和单纯针灸推拿治疗。

关键词：颈椎病/中医疗法血液流变学中药疗法推拿针灸疗法治疗结果

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The Epidemiological Characteristics and Spatiotemporal Clustering of Measles—China,2005-2022

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China CDC weekly 2024年第27期6卷 665-669页

作者： Qianqian liu Jiuhong Li Siyu liu Lin Tang Xiaoqi Wang Aodi Huang Xia Xu Yuexin xiu Hong Yang Ning Wen Lance Rodewald Fuzhen Wang Zundong Yin National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Immunization ProgramChinese Center for Disease Control and PreventionBeijingChina

Introduction:In recent years,the incidence of measles in China has consistently remained below 1 per 100,000 population,yet the disease has not been *** study aims to comprehensively analyze the epidemiological characteristics of measles from 2005 to 2022,identify high-risk populations and areas,and propose targeted ***:We utilized data from the China Disease Prevention and Control Information System for our comprehensive *** autocorrelation was employed to examine the spatial clustering of measles,while spatiotemporal scanning analysis was used to detect spatiotemporal clustering to describe measles epidemiology during the study ***:Between 2005 and 2022,732,218 measles cases were reported in ***,the incidence of measles exhibited a downward trend,particularly during the periods of 2008-2011 and *** 2022,the incidence rate reached its historical low at 0.039 per 100,000 *** predominantly affects young *** 2017,global spatial clustering has diminished,although hotspot areas persist in the western ***-temporal scanning identified a high-incidence cluster from 2005 to 2008,comprising 15 provinces in the western,central,and northern regions of ***,from 2016 to 2022,a low-incidence cluster was detected in the southern and central ***:China has made significant progress in measles prevention and *** recent low incidence and absence of substantial spatiotemporal clustering indicate that China is nearing measles ***,there is a continuing need to enhance prevention and control efforts among very young children and in historic incidence hotspots in western ***,improving the diagnosis of vaccine-associated rash illnesses is essential.

关键词： prevention Spatial utilized

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Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 444-453页

作者： Cheng-Cheng Yang xiu-Xia Yang Xiao-Jing Zhao Heng Wang Zi-Han Guo Kai Jin Yang liu Bin-Hui Li Department of Ophthalmology the Fifth Affiliated HospitalSun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Department of Ophthalmology Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310006Zhejiang ProvinceChina Eye Institute of Xiamen University Fujian Provincial Key Laboratory of Ophthalmology and Visual ScienceSchool of MedicineXiamen UniversityXiamen 361005Fujian ProvinceChina

●AIM:To evaluate the role of semaphorin 7A(Sema7A)and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells(HCEs).●METHODS:Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0,125,250,or 500 ng/mL for 24,48,or 72h in *** electrical resistance(TEER)as well as Dextran-fluorescein isothiocyanate(FITC)permeability assays were conducted to assess barrier *** quantify tight junctions(TJs)such as occludin and zonula occludens-1(ZO-1)at the mRNA level,reverse transcriptionpolymerase chain reaction(RT-PCR)analysis was *** was used to examine the activity of the nuclear factor-kappa B(NF-κB)signaling pathway and the production of TJs *** analyses were employed to localize the ***-linked immunosorbent assay(ELISA)and RT-PCR were utilized to observe changes in interleukin(IL)-1β*** investigate the role of NF-κB signaling activation and IL^(-1)βin Sema7A’s anti-barrier mechanism,we employed 0.1μmol/L IκB kinase 2(IKK2)inhibitor IV or 500 ng/mL IL^(-1)receptor(IL-1R)antagonist.●RESULTS:Treatment with Sema7A resulted in decreased TEER and increased permeability of Dextran-FITC in HCEs through down-regulating mRNA and protein levels of TJs in a time-and dose-dependent manner,as well as altering the localization of ***,Sema7A stimulated the activation of inhibitor of kappa B alpha(IκBα)and expression of IL-1β.The anti-barrier function of Sema7A was significantly suppressed by treatment with IKK2 inhibitor IV or IL-1R antagonists.●CONCLUSION:Sema7A disrupts barrier function through its influence on NF-κB-mediated expression of TJ proteins,as well as the expression of IL-1β.These findings suggest that Sema7A could be a potential therapeutic target for the diseases in corneal epithelium.

关键词： human corneal epithelial barrier function transepithelial electrical resistance zonula occludens-1 occludin nuclear factor-kappa B

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