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Modulating precursor nanosheets for stabilized Ni-rich cathode material for li-ion batteries

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Rare Metals 2022年第8期41卷 2552-2559页

作者： he-Kang zhu Zi-Jia Yin Yu Tang Yang Ren he zhu {2. Luo Si Lan li-Gao Yang Qi liu Department of Physics City University of Hong KongHong Kong999077China Shenzhen Research Institute City University of Hong KongShenzhen518057China School of Economics &ManagementChangsha University of Science and TechnologyChangsha410114China

Ni-rich cathodes have high capacity while low stability,searching for new methods to stabilize the structure has never ***,Ni-rich cathodes liNi_(0.75)-Co_(0.14)Mn_(0.11)O_(2.,with high capacity and good cycling stability,were successfully obtained by reducing the size of primary particles in the precursor[Ni_(0.75)Co_(0.14)Mn_(0.11)](OH)_(2..The Ni-rich cathode,synthesized through this approach,delivers a capacity of 2.6 mAh·g^(-1)and retains92.and 87.7%for 150 cycles at 0.33 C and 300 cycles at1.00 C,*** importantly,the optimal temperature for the final product could be lowered by 1000 C concomitant with this size control,which is conducive to save the manufacture cost and fuel for scale-up *** and dynamic structural investigations reveal that the modulated precursor enables the Ni-rich cathode to reach a combination of a low li/Ni mixing ratio and nanosheet primary particles,which realizes the high capacity and high stability in the meantime.

关键词： stability cycling cathode

浅表软组织普通淋巴管畸形临床病理及遗传学特征分析

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中华病理学杂志 2024年第3期53卷 230-236页

作者：刘秋雨李春晓刘大看薛霜付芳芳朱晓爽孔令非董长宪河南省人民医院郑州大学人民医院病理科郑州450003 河南省巩义市人民医院病理科巩义451200 河南省人民医院郑州大学人民医院血管瘤外科郑州450003 河南省人民医院郑州大学人民医院医学影像中心郑州450003

目的探讨发生于浅表软组织的单纯性普通淋巴管畸形(common lymphatic malformation,CLM)临床病理学特征、分型和遗传学特征,以及分型与上述特征间的相关性。方法回顾性收集河南省人民医院2.19年8月至2.2.年8月手术切除CLM病例110例,分... 详细信息

目的探讨发生于浅表软组织的单纯性普通淋巴管畸形(common lymphatic malformation,CLM)临床病理学特征、分型和遗传学特征,以及分型与上述特征间的相关性。方法回顾性收集河南省人民医院2.19年8月至2.2.年8月手术切除CLM病例110例,分析临床及病理学信息,并行相关免疫组织化学染色及PIK3CA基因荧光定量PCR检测,随访患者。结果110例患者中男性53例,女性57例,65例(65/110,59.1%)为≤2.时首次发现,常见于头颈部(41/110,37.3%),102.(102.110,92.7%)为单灶,83例(83/110,75.5%)为肤色肿块,69例(69/110,62.7%)边界不清,10例(10/110,9.1%)为弥漫性大面积重症表现。CLM的分型中,巨囊型52.(52.110,47.3%),微囊型2.例(2./110,2..9%),混合型35例(35/110,31.8%)。巨囊型CLM大体上表现为柔软半透明肿块,切面可见大囊腔;镜下由大的不规则扩张管壁组成,管壁较厚,常有不规则平滑肌及淋巴细胞浸润。微囊型CLM大体上表现为皮肤表面疣状突起或半透明水泡,切面多呈细小蜂窝状结构;镜下由圆形或成角的扩张小淋巴管组成,管壁少或无平滑肌。混合型兼具巨囊型和微囊型的形态学表现。免疫组织化学染色显示淋巴管内皮细胞呈LYVE-1、D2.40、PROX1、CD31、VEGFR3阳性,CD34阴性;巨囊型及局灶混合型淋巴管壁呈平滑肌肌动蛋白阳性。13例CLM中8例存在PIK3CA基因点突变。所有患者获随访,2.例(2./110,2..8%)术后复发,其多见于混合型,其次为微囊型。结论CLM是异常淋巴管扩张形成的先天性脉管畸形,存在PIK3CA基因突变;不同分型间临床病理学表现存在差异,鉴于微囊型和混合型较易复发,病理诊断应尽可能给予精准分型以指导疾病治疗和预后判断。

关键词：淋巴管畸形淋巴管瘤基因

Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo

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Military Medical Research 2022年第3期9卷 331-350页

作者： Ying he Xun-Hu dong Qiong zhu Ya-li Xu Ming-liang Chen Zheng {2. Department of Ultrasound Xinqiao HospitalThird Military Medical University(Army Medical University)Chongqing400037China Department of Chemical defense Medicine School of Military Preventive MedicineThird Military Medical University(Army Medical University)Chongqing400038China Institute of Toxicology School of Military Preventive MedicineThird Military Medical University(Army Medical University)Chongqing400038China Institute of Pathology and Southwest Cancer Centre Southwest HospitalThird Military Medical University(Army Medical University)Chongqing400038China

Background:Ultrasound-triggered microbubble destruction(UTMD) is a widely used noninvasive technology in both military and civilian medicine,which could enhance radiosensitivity of various ***,little information is available regarding the effects of UTMD on radiotherapy for glioblastoma or the underlying *** study aimed to delineate the effect of UTMD on the radiosensitivity of glioblastoma and the potential involvement of ***:GL2.1,U2.1 cells and orthotopic glioblastoma-bearing mice were treated with ionizing radiation(IR) or IR plus *** was observed by confocal microscopy and transmission electron *** blotting and immunofluorescence analysis were used to detect progesterone receptor membrane component 1(PGRMC1),light chain 3 beta 2.LC3B2. and sequestosome 1(SQSTM1/p62. *** vectors or siRNAs transfection,and fluorescent probes staining were used to explore the underlying ***:UTMD enhanced the radiosensitivity of glioblastoma in vitro and in vivo(Phesis in IR-treated glioblastoma *** of autophagy by 3-methyladenine,bafilomycin A1 or ATG5 siRNA had no significant effect on UTMD-induced radiosensitization in glioblastoma cells(Phen autophagy was induced by rapamycin or ATG5 overexpression(P>0.05).Furthermore,UTMD inhibited PGRMC1expression and binding with LC3B2.in IR-exposed glioblastoma cells(P2.5 or PGRMC1siRNA pretreatment enhanced UTMD-induced LC3B2.and p62.accumulation in IR-exposed glioblastoma cells,thereby promoting UTMD-mediated radiosensitization(Plished UTMD-caused blockade of autophagic degradation,subsequently inhibiting UTMD-induced radiosensitization of glioblastoma ***,compared with IR plus UTMD group

关键词： Ultrasound-triggered microbubble destruction Radiosensitization Progesterone receptor membrane component 1 Autophagy Glioblastoma

穗肥施钾量和叶面肥对稻虾共作水稻生理特性、产量和品质的影响

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河南农业科学 2024年第5期53卷 30-39页

作者：董洪瑞朱杰周勇李皓轩杨伟蒋梦蝶朱波聂江文刘章勇长江大学农学院/湿地生态与农业利用教育部工程研究中心湖北荆州434200 襄阳市农业科学院湖北襄阳441000 湖北工程学院生命科学技术学院湖北孝感432000

研究穗肥施钾量[0 kg/hm^(2.(S0)、45 kg/hm^(2.(S1)、90 kg/hm^(2.(S2.]和叶面肥[不喷施叶面肥(P0)和喷施叶面肥(P1)]对稻虾共作水稻生理特性、产量和品质的影响,以期为稻虾共作模式下的水稻绿色高产优质栽培提供科学依据。结果表明,... 详细信息

研究穗肥施钾量[0 kg/hm^(2.(S0)、45 kg/hm^(2.(S1)、90 kg/hm^(2.(S2.]和叶面肥[不喷施叶面肥(P0)和喷施叶面肥(P1)]对稻虾共作水稻生理特性、产量和品质的影响,以期为稻虾共作模式下的水稻绿色高产优质栽培提供科学依据。结果表明,喷施叶面肥、施用穗肥钾均可提高水稻剑叶SPAD值,超氧化物歧化酶(SOD)活性,核酮糖-1,5-二磷酸羧化酶(RuBisCO)活性,过氧化物酶(POD)活性,可溶性糖含量,地上部干物质积累量,茎叶干物质转运量、转运率及其对籽粒的贡献率,同时降低丙二醛(MDA)含量,总体上以S1P1处理最优。喷施叶面肥、施用穗肥钾均可提高穗实粒数、结实率,进而提高产量,P1处理使S0、S1和S2.件下产量分别增加13.60%、9.76%和6.55%,S1和S2.理使产量分别提高3.70%和2.47%,以S1P1处理产量最高。与P0处理相比,S0和S1条件下,P1处理稻米的整精米率分别显著提高2.2.%和1.82.,垩白粒率显著降低55.88%和50.01%,垩白度显著降低49.98%和50.00%,总蛋白质含量显著降低8.77%和12.08%;与S0处理相比,S1和S2.理稻米的垩白粒率分别显著降低11.2.%和30.61%,S1处理稻米的总蛋白质含量显著降低4.15%;总体以S1P1处理效果最好。综合来看,喷施叶面肥、施用穗肥钾可以改善叶片光合作用,提高地上部干物质的积累、转运,提高产量和品质,以S1P1处理效果最好。

关键词：水稻叶面肥穗钾肥用量产量生理特性品质稻虾共作

Clinical and Genetic Diagnosis of 40 Cases of Primary Immunodeficiency Diseases

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Clinical and Genetic Diagnosis of 40 Cases of Primary Immuno...

基于有界分类器的深度学习青铜器年代鉴别方法

第五届亚洲儿科研究大会

作者： li-ping Jiang~1 Guan-rong Chen~2.Xiao-dong Zhao~1 Feng-shan Huo~2.En-mei liu~1 Chao-min {2.~1 Wen-weiTu~2.Ping Fang~1 Hui li~1 Jie Yu~1 Xue-mei Tang~1 wei liu~1 Mo Wang~1 Jia-li Wang~1 Yao Zhao~1 Na Xie~1 Shu-juan li~1 Xi-qiang Yang~1 Yu-long liu~2.1.Children’s Hospital of Chongqing Medical university Chongqing 400014 {2. 2.Department of Paediatrics and Adolescent Medicine li Ka Shing Faculty of Medicine The university of Hong Kong HKSAR {2. Children''s Hospital of Chongqing Medical university Chongqing 400014China Department of Paediatrics and Adolescent MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHKSARChina

＜正＞Objective To analyze and conclude clinical status and gene mutations of 40 cases of 8 kinds of primary immunodeficiency diseases from 2.00 to 2.08. Methods Based on the clinical manifestations and immunological screening tests,the genomic DNAs of 40 patients and their family members were detected by PCR-directed sequencing of the corresponding pathogenic genes of these PID patients.

关键词：

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激光与光电子学进展 2024年第8期61卷 192-200页

作者：李佰强潘光绪李天倩朱冬白露阳小明刘培刚文坤强西华大学电气与电子信息学院四川成都610036 民航成都电子技术有限责任公司四川成都610041 成都川哈工机器人及智能装备产业技术研究院有限公司四川成都610041 成都文物考古研究院文物考古工作队四川成都610031

针对古青铜器年代鉴别任务需要大量的相关史料、鉴别耗时长以及主观性强等问题,提出一种新思路用于辅助考古专家对古青铜器进行分析和年代鉴别。所提方法在图像分类预训练权重的基础上应用深度学习方法对古青铜器进行年代鉴别:首先,通... 详细信息

针对古青铜器年代鉴别任务需要大量的相关史料、鉴别耗时长以及主观性强等问题,提出一种新思路用于辅助考古专家对古青铜器进行分析和年代鉴别。所提方法在图像分类预训练权重的基础上应用深度学习方法对古青铜器进行年代鉴别:首先,通过大量的基础实验,在较为有代表性的4种网络模型中选出鉴别结果较好的EfficientNetV2.L作为基线模型;接下来,使用EfficientNetV2.L对古青铜器数据集进行特征提取;然后,将原有的线性分类层替换为cosin_classifier,减小方差带来的风险,提高模型鉴别能力;最后,引入Focal损失函数替换原有的交叉熵损失函数进行损失计算,在聚焦因子(focusing parameter)和加权因子(class weighting)作用下有效地改善样本数量较少类别所导致的模型学习效果较差的问题。所提方法较原始EfficientNetV2.L在准确率、精确率、召回率、F1分数和曲线下面积等指标上提高4.1百分点、4.0百分点、4.1百分点、4.2.分点和0.9百分点,在测试集上取得91.7%的最优准确率。在此基础上,还对分期有争议的青铜器进行了模型预测分析。结果表明,深度学习技术在古青铜器数据集年代鉴别任务上是有效的,可提供参考分析数据,减轻考古专家的工作强度。

关键词：图像处理深度学习青铜器 EfficientNetV2 年代鉴别

丁咯地尔与尼莫地平治疗血管性痴呆的双盲对照研究

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中国新药与临床杂志 2002年第2期21卷 74-76页

作者：刘赛男李义召韩丹春迟兆富张锐王宁庭赵富华朱屹东山东医科大学附属医院齐鲁制药厂药物研究所山东济南250001

目的 :比较丁咯地尔与尼莫地平治疗血管性痴呆的临床疗效。方法 :70例血管性痴呆病人 ,以双盲随机对照研究方法分为尼莫地平组 35例 ,丁咯地尔组 35例。分别给尼莫地平 30mg ,丁咯地尔15 0mg ,po ,tid ,8wk为一个疗程。治疗后评价MMSE ,... 详细信息

目的 :比较丁咯地尔与尼莫地平治疗血管性痴呆的临床疗效。方法 :70例血管性痴呆病人 ,以双盲随机对照研究方法分为尼莫地平组 35例 ,丁咯地尔组 35例。分别给尼莫地平 30mg ,丁咯地尔15 0mg ,po ,tid ,8wk为一个疗程。治疗后评价MMSE ,HDS ,ADL ,WMS ,CGI ,EI及不良反应。结果 :治疗后WMS ,MMSE ,ADL ,CGI ,EI评分尼莫地平组为 (5 9± 2.2.,2.0± 6 ,30± 12.,3.0± 0 .7,1.9±0 .7)分 ;丁咯地尔组为 (70± 18,2.2. 4 ,2.6± 9,2..2.0 .9,2..5± 0 .8)分 ,2.比较P 1,2.不良反应比较P >0 .0 5。结论

关键词：丁咯地尔尼莫地平片剂血管性痴呆双盲法治疗

A draft sequence of the rice (Oryza sativa ssp. indica) genome

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Chinese Science Bulletin 2001年第23期46卷 1937-1942页

作者： YU Jun, HU Songnian, WANG Jun,li Songgang WONG Ka-Shu Gane, liu Bin,DENG Yajun, DAI li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, liu Jing,SUN Jiandong , TANG Jiabin, CheN Yanjiong,HUANG Xiaobing, liN wei, YE Chen, TONG wei,CONG lijuan, GENG Jianing, HAN Yujun, li lin,li wei, HU Guangqiang, HUANG Xiangang,li Wenjie, li Jian, liu Zhanwei, li Long,liu Jianping, Ql Qiuhui, liu Jinsong, li li,WANG Xuegang, LU Hong, WU Tingling,zhu Miao, Nl Peixiang, HAN Hua, dong wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,li Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, he Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZheNG Xianwu, dong Jianhai, ZENG Wanyong,TAO lin, CheN Xuewei, he Jun, liu Daofeng,TIAN wei, TIAN Chaoguang, XIA Hongai,li Gang, GAO Hui, li Ping, CheN wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, liu Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, li Zhijie,MAO Long, ZHOU Chengshu, zhu Zhen,CheN Runsheng, HAO Bailin,ZheNG weimou, CheN Shouyi, QUO wei,li Guojie, liu Siqi, HUANG Guyang,TAO Ming, WANG Jian, zhu lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, china Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang university/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, china Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, china national Hybrid Rice R & D Center, changsha 410125, china Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, china College of life Sciences, Peking university, Beijing 100871, china Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, china Digital china Ltd., Beijing 100080, china Institute of Computing technology, Chinese Academy of Sciences, Beijing 100080, china Medical College, Xi’an Jiaotong university, Xi’an 710061, chinaThese authors contributed equally to this work.Corresponding author.Corresponden Beijing Genomics Institute/Center of Genomics & Bioinformatics Chinese Academy of Sciences Beijing China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang university/Key Laboratory of Bioinformatics of Zhejiang Province Hangzhou China College of life Sciences Peking University Beijing China Medical College Xi’an Jiaotong University Xi’an China Institute of Genetics Chinese Academy of Sciences Beijing China Laboratory of Bioinformatics Institute of Biophysics Chinese Academy of Sciences Beijing China national Hybrid Rice R & D Center Changsha China Institute of Theoretical Physics Chinese Academy of Sciences Beijing China Digital china Ltd. Beijing China Institute of Computing technology Chinese Academy of Sciences Beijing China

The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a "whole genome shotgun" approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in china and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2.14.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.2.% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package

关键词： rice genome draft sequences.

褪黑素浸种对铝胁迫下苜蓿种子萌发及幼苗抗氧化生理的影响

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草地学报 2024年第2期32卷 535-542页

作者：李启娇崔东毅段新慧刘莉许文花李庆玺郑立文任健朱丽敏马向丽云南农业大学云南昆明650201 迪庆州畜牧兽医科学研究院云南香格里拉674400

为探明外源褪黑素(Melatonin, MT)溶液浸种对铝胁迫下紫花苜蓿(Medicago sativa L.)种子萌发及幼苗生长的影响,本试验以‘WL52.HQ’(耐铝)和‘三得利’(敏铝)紫花苜蓿为材料,使用不同浓度MT溶液(0,100,2.0,400,800μmol·L^(-1))浸种,... 详细信息

为探明外源褪黑素(Melatonin, MT)溶液浸种对铝胁迫下紫花苜蓿(Medicago sativa L.)种子萌发及幼苗生长的影响,本试验以‘WL52.HQ’(耐铝)和‘三得利’(敏铝)紫花苜蓿为材料,使用不同浓度MT溶液(0,100,2.0,400,800μmol·L^(-1))浸种,测定铝胁迫(1 mmol·L^(-1))下种子萌发、幼苗生长、幼苗抗氧化生理等指标。结果表明,铝胁迫抑制了紫花苜蓿种子萌发及幼苗生长,MT浸种通过提高抗氧化酶活性、减少H2.2.丙二醛的积累来减轻铝胁迫给紫花苜蓿带来的氧化伤害;且随着MT溶液浓度的增加,紫花苜蓿种子发芽率、发芽势、根长、株高、生物量及根系抗氧化酶活性呈先升后降趋势,H2.2.丙二醛含量呈先降后升趋势,‘WL52.HQ’的变化幅度高于‘三得利’。综合发芽指标、生长指标、抗氧化酶活性、H2.2.丙二醛含量评价不同浓度MT对苜蓿铝毒害的缓解效果表明:2.0μmol·L^(-1)处理效果较好,400μmol·L^(-1)次之,800μmol·L^(-1)最差。

关键词：褪黑素紫花苜蓿铝胁迫种子萌发幼苗生长