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Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression

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World Journal of Psychiatry 2025年第1期15卷 54-62页

作者： juan liu Yan-Ping Guo Yan-Mei Lu Bei-Lin Wang Department of Urology Surgery Zhumadian Central HospitalZhumadian 463000Henan ProvinceChina Department of Psychiatry Zhumadian Mental HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Urinary system tumors often cause negative psychological symptoms,such as depression and dysphoria which significantly impact immune function and indirectly affect cancer *** epirubicin(EPI)is recommended by the European Association of Urology and can improve prognosis,its long-term use can cause toxic side effects,reduce treatment compliance,and increase psycho-logical ***,an appropriate intervention mode is *** This was a retrospective study including 110 patients with urinary system tumors and depression admitted to Zhumadian Central Hospital between March 2021 and July *** were divided into conventional(n=55)and joint inter-vention(n=55)*** conventional group received mitomycin and routine nursing,while the joint intervention group received EPI and mindfulness *** groups underwent three cycles of *** function(CD4+cells,CD8+cells,CD4+/CD8+ratio),tumor marker levels[urinary bladder cancer antigen(UBC),bladder tumor antigen(BTA)and nuclear matrix protein 22(NMP22)],quality of life questionnaire-core 30(QLQ-C30),17-item Hamilton depression scale(HAMD-17),and cancer-related fatigue[cancer fatigue scale(CFS)]were *** reactions and nursing satisfaction were recorded and *** Post-intervention,CD4+,CD8+,and CD4+/CD8+levels increased in both groups,with the joint intervention group showing more significant improvement(P<0.05).Tumor marker levels(NMP22,BTA,and UBC)were lower in the joint intervention group compared to the conventional group(P<0.05).The joint intervention group also showed a greater reduction in HAMD-17 scores(9.38±3.12 vs 15.45±4.86,P<0.05),higher QLQ-C30 scores,and lower CFS scores(both P<0.05).Additionally,the joint intervention group had a lower incidence of adverse reactions and higher nursing satisfaction(P<0.05).CONCLUSION EPI combined with mindfulness intervention significantly improved clinical outcomes in patients with urinar

关键词： Urinary system tumor Bladder cancer Prostate cancer Depression Epirubicin

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内冲击激发式安全雷管的研制与适配性测试

火工品 2025年第1期 1-6页

作者：邓小娟代鹏举董金龙刘晓娟王爱上海鲲程电子科技有限公司上海201100 广东宏大民爆集团有限公司广东广州510000 湖南湘科控股集团有限公司湖南长沙410000 江西新余国泰特种化工有限责任公司江西新余338000 湖南神斧集团湘南爆破器材有限责任公司湖南永州425000

针对工业雷管在使用过程中因起爆药感度高而引发的安全事故和环境污染问题,研制了一种新型内冲击激发式安全雷管(简称“IID雷管”),并开展其与不同点火药的适配性测试。通过采用猛炸药作为主要装药,以及设计激发组件,实现了高效有序的... 详细信息

针对工业雷管在使用过程中因起爆药感度高而引发的安全事故和环境污染问题,研制了一种新型内冲击激发式安全雷管(简称“IID雷管”),并开展其与不同点火药的适配性测试。通过采用猛炸药作为主要装药,以及设计激发组件,实现了高效有序的起爆和传爆过程;通过与不同点火药的适配测试,以及对起爆能力、延期精度等关键功能的全面评估,验证了IID雷管在与LTNR和K-K等药剂适配时,各项性能均满足行业标准。此外,IID雷管结构工艺简单、安全环保,具有广泛的应用前景。

关键词：安全雷管数码电子雷管内冲击激发无起爆药雷管激发组件

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基于能值法对区域系统的数据采集与应用研究

天津理工大学学报 2025年第1期41卷 145-152页

作者：郝如毅刘娟天津理工大学环境科学与安全工程学院

呼包鄂榆城市群是我国西北地区重要的城市群中心。基于能值理论的分析方法，对2020年呼包鄂榆城市群发展的各项数据进行采集、整理、计算后进行综合分析。结果显示：2020年呼包鄂榆城市群总能值中可更新资源能值的占比为0.24%、不可更... 详细信息

呼包鄂榆城市群是我国西北地区重要的城市群中心。基于能值理论的分析方法，对2020年呼包鄂榆城市群发展的各项数据进行采集、整理、计算后进行综合分析。结果显示：2020年呼包鄂榆城市群总能值中可更新资源能值的占比为0.24%、不可更新资源能值的占比较高，达95.67%;能值自给率为96%;区域环境负载率较高；能值产出率为24.46%;城市群能值密度和人均能值量超全国平均水平。可持续指标显示城市群为高度发达的“消费者”导向型经济体；健康能值指数表明呼包鄂榆城市群在城市健康评分分级标准中判定为“很健康”。最后根据数据结论，对呼包鄂榆城市群健康发展提出针对性对策和建议。

关键词：呼包鄂榆城市群能值理论可持续发展健康指数

Review of computer-generated hologram algorithms for color dynamic holographic three-dimensional display

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Light(Science & Applications) 2022年第9期11卷 1962-1978页

作者： Dapu Pi juan liu Yongtian Wang Beijing Engineering Research Center for Mixed Reality and Advanced Display School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China

Holographic three-dimensional display is an important display technique because it can provide all depth information of a real or virtual scene without any special *** recent years,with the development of computer and optoelectronic technology,computer-generated holograms have attracted extensive attention and developed as the most promising method to realize holographic ***,some bottlenecks still restrict the development of computer-generated holograms,such as heavy computation burden,low image quality,and the complicated system of color holographic *** overcome these problems,numerous algorithms have been investigated with the aim of color dynamic holographic three-dimensional *** this review,we will explain the essence of various computer-generated hologram algorithms and provide some insights for future research.

关键词： holographic dynamic overcome

Sparse Weighted Canonical Correlation Analysis

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Chinese Journal of Electronics 2018年第3期27卷 459-466页

作者： MIN Wenwen liu juan ZHANG Shihua State Key Laboratory of Software Engineering School of Computer Wuhan University National Center for Mathematics and Interdisciplinary Sciences Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematics Sciences University of Chinese Academy of Sciences

Given two data matrices X and Y, Sparse canonical correlation analysis（SCCA） is to seek two sparse canonical vectors u and v to maximize the correlation between Xu and Yv. Classical and sparse Canonical correlation analysis（CCA） models consider the contribution of all the samples of data matrices and thus cannot identify an underlying specific subset of samples. We propose a novel Sparse weighted canonical correlation analysis（SWCCA）,where weights are used for regularizing different *** solve the L;-regularized SWCCA（L;-SWCCA） using an alternating iterative algorithm. We apply L;-SWCCA to synthetic data and real-world data to demonstrate its effectiveness and superiority compared to related methods. We consider also SWCCA with different penalties like Least absolute shrinkage and selection operator（LASSO）and Group LASSO, and extend it for integrating more than three data matrices.

关键词： Canonical correlation analysis(CCA) Sparse canonical correlation analysis(SCCA) Sparse weighted CCA(SWCCA) Group LASSO regularized SWCCA Multi-view SWCCA

Structural and functional analysis of an asymmetric bidirectional promoter in Arabidopsis thaliana

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Journal of Integrative Plant Biology 2015年第2期57卷 162-170页

作者： Shi-juan liu Qiu-juan Yue Wei Zhang Key Laboratory of Plant Cell Engineering and Germplasm Innovation Ministry of Education School of Life Sciences Shandong University College of Life Science Qufu Normal University

Bidirectional promoters are relatively abundant in eukaryotic genomes, suggesting that they have an important biological significance. As yet, few of these promoters have been characterized in detail. Here, using a promoter：：GUS transgene approach has revealed that the intergenic region of Arabidopsis thaliana divergent genes At1g71850 and At1g71860 is an asymmetric bidirectional promoter, which exhibits an orientation-dependent expression profile. The strength of the forward promoter was greater than that of the reverse promoter, and their tissue specificities were not identical. Deletion analyses revealed that this bidirectional promoter could be divided into three functional regions. The basal level and tissue specificity of the promoter in the reverse orientation were regulated positively by region II and negatively by region III, whereas promoter activity in the forward orientation was regulated negatively by region II and positively by region I. Thus the 52-bp stretch of region II had a dual function, enhancing expression in the reverse orientation and suppressing it in the forward orientation. These results demonstrated that the activity of the At1g71850-At1g71860 bidirectional promoter was modulated by complex interactions between both positive and negative cis-acting elements. These findings will enhance our understanding of the regulatory mechanisms of plant bidirectional promoters.

关键词： GUS (β-glucuronidase) positive and negative regulatoryelement promoter strength tissue-specific expression

Sparse recovery method for far-field and near-field sources localization using oblique projection

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The Journal of China Universities of Posts and Telecommunications 2013年第3期20卷 90-96页

作者： WANG Bo ZHAO Yan-ping liu juan-juan College of Communication Engineering Jilin University

In this paper, we propose a novel source localization method to estimate parameters of arbitrary field sources, which may lie in near-field region or far-field region of array aperture. The proposed method primarily constructs two special spatial-temporal covariance matrixes which can avoid the array aperture loss, and then estimates the frequencies of signals to obtain the oblique projection matrixes. By using the oblique projection technique, the covariance matrixes can be transformed into several data matrixes which only contain single source information, respectively. At last, based on the sparse signal recovery method, these data matrixes are utilized to solve the source localization problem. Compared with the existing typical source localization algorithms, the proposed method improves the estimation accuracy, and provides higher angle resolution for closely spaced sources scenario. Simulation results are given to demonstrate the performance of the proposed algorithm.

关键词： array signal processing near-field far-field sparse signal recovery oblique projection

Advances in innate immune signaling:new activators and regulators

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National Science Review 2016年第2期3卷 160-162页

作者： juan liu Xuetao Cao National Key Laboratory of Medical Immunology & Institute of Immunology Second Military Medical University National Key Laboratory of Medical Molecular Biology & Department of Immunology Institute of Basic Medical SciencesChinese Academy of Medical Sciences

The innate immune system can detect the invading microbe components via three major pattern recognition receptorsToll-like receptors,RIG-I-like receptors and NOD-like receptors as well as a variety of cytoplasmic DNA or RNA *** innate receptors induce a series of intracellular downstream signaling pathways,leading to the efficient innate immune responses to eliminate pathogens(Fig.1).Meanwhile,

关键词： Advances in innate immune signaling IKK DNA TLR

A 220 GHz Orthogonal Modulator Based on Subharmonic Mixers Using Anti-Paralleled Schottky Diodes

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Chinese Journal of Electronics 2022年第3期31卷 562-568页

作者： HE Yue liu Ge liu juan LIN Changxing SU Wei Microsystem and Terahertz Research Center China Academy of Engineering Physics Institute of Electronic Engineering China Academy of Engineering Physics

In this paper, A 220 GHz orthogonal modulator based on two symmetrical subharmonic mixers is designed, analyzed and measured, where the mixers are implemented basde on antiparallel Schottky *** orthogonal modulator consists of a 90° phase shifted220 GHz 3 d B coupler, two sub-harmonically pumped mixers and an in-phase 110 GHz 3 d B power divider. The IF output signals are in-phase(I) branch and quadrature(Q) branch operating from DC±3.5 GHz. In the back to back experimentaltests, it is shown that the conversion loss of the two 220 GHz I/Q mixers is less than 30 d B when the IF operating frequency is DC-3.5 GHz, IF input power is-10 d Bm and the LO power is around 6 m W. Based on floating-point simulation, the amplitude and phase imbalance of the I/Q mixer are less than 0.2 d B and 2 degree respectively. When the 220 GHz modulator and demodulator are set in a back to back configuration, a signal-to-noise ratio of 21 d B can be obtained using the 16 QAM modulation type.

关键词： subharmonic mixers amplitude imbalance I-Q mixer floating-point simulation power dividers millimetre wave mixers millimetre wave diodes waveguide couplers quadrature amplitude modulation Schottky diode mixers radio-over-fibre phase imbalance orthogonal modulator power divider 16 QAM modulation subharmonically pumped mixers quadrature branch in-phase branch antiparalleled Schottky diodes waveguide coupler