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Pickering emulsion transport in skeletal muscle tissue:A dissipative particle dynamics simulation approach

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Chinese Journal of Chemical Engineering 2024年第4期68卷 65-75页

作者： Xuwei liu Wei Chen Yufei Xia Guanghui Ma Reiji Noda Wei ge State Key Laboratory of Mesoscience and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China Division of Environmental Engineering Science Graduate School of Science and TechnologyGunma University1-5-1 Tenjin-choKiryuGunma 376-8515Japan State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China

Lymph node targeting is a commonly used strategy for particulate vaccines,particularly for Pickering ***,extensive research on the internal delivery mechanisms of these emulsions,especially the complex intercellular interactions of deformable Pickering emulsions,has been surprisingly *** gap in knowledge holds significant potential for enhancing vaccine *** study aims to address this by summarizing the process of lymph-node-targeting transport and introducing a dissipative particle dynamics simulation method to evaluate the dynamic processes within cell *** transport of Pickering emulsions in skeletal muscle tissue is specifically investigated as a case *** factors impacting the transport process are explored,including local cellular tissue environmental factors and the properties of the Pickering emulsion *** simulation results primarily demonstrate that an increase in radial repulsive interaction between emulsion particles can decrease the transport ***,larger intercellular gaps also diminish the transport efficiency of emulsion droplet particles due to the increased motion complexity within the intricate transport space compared to a single *** study sheds light on the nuanced interplay between engineered and biological systems influencing the transport dynamics of Pickering *** insights hold valuable potential for optimizing transport processes in practical biomedical applications such as drug ***,the desired transport efficiency varies depending on the specific *** instance,while a more rapid transport might be crucial for lymph-node-targeted drug delivery,certain applications requiring a slower release of active components could benefit from the reduced transport efficiency observed with increased particle repulsion or larger intercellular gaps.

关键词： Pickering emulsion Skeletal muscular cells Transport phenomena Dissipative particle dynamics Drug delivery

Stochastic Gradient Compression for Federated Learning over Wireless Network

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China Communications 2024年第4期21卷 230-247页

作者： Lin Xiaohan liu Yuan Chen Fangjiong Huang Yang ge Xiaohu School of Electronic and Information Engineering South China University of TechnologyGuangzhou 510641China Key Laboratory of Dynamic Cognitive System of Electromagnetic Spectrum Space Ministry of Industry and Information TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016China School of Electronic Information and Communications Huazhong University of Science and TechnologyWuhan 430074China

As a mature distributed machine learning paradigm,federated learning enables wireless edge devices to collaboratively train a shared AI-model by stochastic gradient descent(SGD).However,devices need to upload high-dimensional stochastic gradients to edge server in training,which cause severe communication *** address this problem,we compress the communication by sparsifying and quantizing the stochastic gradients of edge *** first derive a closed form of the communication compression in terms of sparsification and quantization ***,the convergence rate of this communicationcompressed system is analyzed and several insights are ***,we formulate and deal with the quantization resource allocation problem for the goal of minimizing the convergence upper bound,under the constraint of multiple-access channel *** show that the proposed scheme outperforms the benchmarks.

关键词： federated learning gradient compression quantization resource allocation stochastic gradient descent(SGD)

Weighted Linear Loss Large Margin Distribution Machine for Pattern Classification

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Chinese Journal of Electronics 2024年第3期33卷 753-765页

作者： ling liu Maoxiang CHU Rongfen GONG Liming liu Yonghui YANG School of Electronic and Information Engineering University of Science and Technology Liaoning

Compared with support vector machine,large margin distribution machine(LDM) has better generalization *** central idea of LDM is to maximize the margin mean and minimize the margin variance *** the computational complexity of LDM is *** order to reduce the computational complexity of LDM,a weighted linear loss LDM(WLLDM) is *** framework of WLLDM is built based on LDM and the weighted linear *** weighted linear loss is adopted instead of the hinge loss in *** modification can transform the quadratic programming problem into a simple linear equation,resulting in lower computational ***,WLLDM has the potential to deal with large-scale *** WLLDM is similar in principle to the LDM algorithm,which can optimize the margin distribution and achieve better generalization *** WLLDM algorithm is compared with other models by conducting experiments on different *** results show that the proposed WLLDM has better generalization performance and faster training speed.

关键词： Training Support vector machines Pattern classification Transforms Fasteners Mathematical models Vectors

Cross-diffusion induced Turing instability of Hopf bifurcating periodic solutions in the reaction-diffusion enzyme reaction model

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International Journal of Biomathematics 2024年第4期17卷 133-150页

作者： Haicheng liu Wenshuo Yuan Bin ge Jihong Shen College of Mathematical Sciences Harbin Engineering University Harbin 150001 HeilongjiangP.R.China

Aiming at the spatial pattern phenomenon in biochemical reactions,an enzyme-reaction Sporns-Seelig model with cross-diffusion is chosen as study *** the central manifold theory,normal form method,local Hopf bifurcation theorem and perturbation theory,we study Turing instability of the spatially homogeneous Hopf bifurcation periodic *** last,the theoretical results are verified by numerical simulations.

关键词： Sporns-Seelig model diffusion Hopf bifurcation periodic solutions Turing instability

Influence of ammonium sulfate on the corrosion behavior of AZ31 magnesium alloy in chloride environment

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Journal of Magnesium and Alloys 2024年第3期12卷 1082-1101页

作者： Feng ge Zhongyu Cui Yue liu Li Lei Xin Wang Hongzhi Cui School of Materials Science and Engineering Ocean University of ChinaQingdao 266100China Beijing National Innovation Institute of Lightweight Ltd.Beijing 101499China

Electrochemical corrosion of AZ31 magnesium alloy in the NH_(4)^(+)-SO_(4)2−-Cl−environment is *** of NH_(4)^(+)overshadows that of Cl−as the(NH_(4))_(2)SO_(4) concentration is 0.005 M or higher,yielding an evolution from localized corrosion to uniform *** effect of NH_(4)^(+)can be attributed to that(i)NH_(4)^(+)dissolves the inner MgO and hinders the precipitation of Mg(OH)_(2) and(ii)the buffering ability of NH_(4)^(+)provides H+,enhances the hydrogen evolution,and expedites the corrosion *** latter is demonstrated as the dominant factor with the results in unbuffered and buffered *** severe corrosion and hydrogen process in NH_(4)^(+)-containing solution results in a high Hads coverage and yields an inductive loop within the low ***,SO_(4)^(2−)is helpful in generating cracked but partially protective corrosion products,while Cl−could broaden the corrosion area beneath the corrosion product.

关键词： Magnesium alloy Ammonium corrosion Electrochemical kinetic parameter Anodic dissolution.

Interference of harmonics emitted by different tunneling momentum channels in laser fields

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Chinese Physics B 2024年第9期33卷 366-372页

作者： ling-Yu Zhang Zhuo-Xuan Xie Can Wang Xin-Lei ge Jing Guo Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China College of Physical Science and Technology Bohai UniversityJinzhou 121013China

By numerically solving the semiconductor Bloch equation(SBEs),we theoretically study the high-harmonic generation of ZnO crystals driven by one-color and two-color intense laser *** results show the enhancement of harmonics and the cut-off remains the same in the two-color field,which can be explained by the recollision trajectories and electron excitation from *** on the quantum path analysis,we investigate contribution of different ranges of the crystal momentum k of ZnO to the harmonic yield,and find that in two-color laser fields,the intensity of the harmonic yield of different ranges from the crystal momentum makes a big difference and the harmonic intensity is depressed from all k channels,which is related to the interferences between harmonics from symmetric k channels.

关键词： high-order harmonic generation the semiconductor Bloch equation k-resolved inter-band harmonic

Unmanned Ship Identification Based on Improved YOLOv8s Algorithm

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Computers, Materials & Continua 2024年第3期78卷 3071-3088页

作者： Chun-Ming Wu Jin Lei Wu-Kai liu Mei-ling Ren ling-Li Ran Key Laboratory of Modern Power System Simulation and Control&Renewable Energy Technology School of Electrical EngineeringNortheast Electric Power UniversityJilin132012China School of Biomedical Engineering Taiyuan University of TechnologyTaiyuan030600China

Aiming at defects such as low contrast in infrared ship images,uneven distribution of ship size,and lack of texture details,which will lead to unmanned ship leakage misdetection and slow detection,this paper proposes an infrared ship detection model based on the improved YOLOv8 algorithm(R_YOLO).The algorithm incorporates the Efficient Multi-Scale Attention mechanism(EMA),the efficient Reparameterized generalized-feature extraction module(CSPStage),the small target detection header,the Repulsion Loss function,and the context aggregation block(CABlock),which are designed to improve the model’s ability to detect targets at multiple scales and the speed of model *** algorithm is validated in detail on two vessel *** comprehensive experimental results demonstrate that,in the infrared dataset,the YOLOv8s algorithm exhibits improvements in various performance ***,compared to the baseline algorithm,there is a 3.1%increase in mean average precision at a threshold of 0.5(mAP(0.5)),a 5.4%increase in recall rate,and a 2.2%increase in mAP(0.5:0.95).Simultaneously,while less than 5 times parameters,the mAP(0.5)and frames per second(FPS)exhibit an increase of 1.7%and more than 3 times,respectively,compared to the CAA_YOLO ***,the evaluation indexes on the visible light data set have shown an average improvement of 4.5%.

关键词： Unmanned ships R_YOLO EMA CSPStage YOLOv8s

Differentiation of marrow-derived islet-like cells and their effects on diabetic rats

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Chinese Medical Journal 2010年第22期123卷 3347-3350页

作者： liu ge-ling LU Yi-fang LI Wei-juan XIAO Hong-zhen SUN Guo-gui YU Fang XIANG Xiu-xiu ZHANG Hui-qin liu Xiu-ling SHI Yan-ping LI Sha Department of Endocrinology Tangshan Worker's Hospital Tangshan Hebei 063000 China Department of Radiation Oncology Fourth Hospital of Hebei Medical University Shijiazhuang Hebei 050017 China

In recent years, islet transplantation for diabetes has shown signs of the treatment efficacy, but its application is limited due to lack of donor organizations, sources and immune rejection. Bone marrow mesenchymal stem cells （BMSCs） have become a new resource of islet cell substitutes. One focus of the current research is the application of a specific inducing agent or a culture system to get directed differentiation of BMSCs, which may have part characteristics of islet cells and then be used in autologous transplantation for the treatment of diabetes.

关键词： rats bone marrow mesenchymal stem cells induction in vitro

A unified Minorization-Maximization approach for estimation of general mixture models

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 343-362页

作者： HUANG Xi-fen liu Deng-ge ZHOU Yun-peng ZHU Fei School of Mathematics Yunnan Normal UniversityKunming 650092China Department of Statistics and Actuarial Science The University of Hong KongHong KongChina

The mixed distribution model is often used to extract information from heteroge-neous data and perform modeling *** the density function of mixed distribution is complicated or the variable dimension is high,it usually brings challenges to the parameter es-timation of the mixed distribution *** application of MM algorithm can avoid complex expectation calculations,and can also solve the problem of high-dimensional optimization by decomposing the objective *** this paper,MM algorithm is applied to the parameter estimation problem of mixed distribution *** method of assembly and decomposition is used to construct the substitute function with separable parameters,which avoids the problems of complex expectation calculations and the inversion of high-dimensional matrices.

关键词： MM algorithm mixed distribution model parameter estimation assembly decomposition tech-nology parameter separation