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Horticulture Research 2021年第1期8卷 2023-2034页

作者： Jingru Li Shanshan Seng Donglei Li Fengqin Zhang Yixuan liu Ting Yao Jiahui liang Mingfang Yi Jian Wu Beijing Key Laboratory of Development and Quality Control of Ornamental Crops Department of Ornamental Horticulture and Landscape ArchitectureChina Agricultural UniversityBeijingChina

Understanding corm development in flower bulbs is of importance for securing the quality of cut flowers and propagation of commercial *** is one of the most popular bulb plants *** corm development is characterized by starch *** research has shown that phytohormones(especially gibberellin(GA))are involved in tuber ***,the relationship between abscisic acid(ABA)/GA and starch during corm development remains *** gain deeper insights into the biological process of corm development,we performed a detailed anatomical characterization of different stages of corm development and analyzed phytohormone *** study showed that corm development is linked to hormones(ABA and GA)and carbohydrates(sucrose and starch).Exogenous hormone treatment and silencing of endogenous hormone biosynthesis genes indicated that ABA positively regulates corm development,while GA acts as an antagonist of ABA function.A sucrose synthase gene(GhSUS2)was shown to be involved in the antagonism between ABA and ***2 was upregulated by ABA and downregulated by *** increase in the transcript level of GhSUS2 coincided with the development of corm/*** of GhSUS2 repressed corm development and starch *** conclusion,we propose that GhSUS2,an essential enzyme in sucrose degradation,is differentially regulated by ABA and GA and controls corm development in Gladiolus.

关键词： function synthesis conclusion

Human neural stem cells promote corticospinal axons regeneration and synapse reformation in injured spinal cord of rats

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Chinese Medical Journal 2006年第16期119卷 1331-1338页

作者： liang Peng JIN Lian-hong liang Tao liu En-zhong Shi-guang Department of Neurosurgery First Clinical College Harbin Medical University Harbin 150001 China Department of Histology and Embryology Basic Medical Science College Harbin Medical University Harbin 150001 China Department of Digestion First Clinical College Harbin Medical University Harbin 150001 China

Background Axonal regeneration in lesioned mammalian central nervous system is abortive, and this causes permanent disabilities in individuals with spinal cord injuries. This paper studied the action of neural stem cell （NSC） in promoting corticospinal axons regeneration and synapse reformation in rats with injured spinal cord. Methods NSCs were isolated from the cortical tissue of spontaneous aborted human fetuses in accordance with the ethical request. The cells were discarded from the NSC culture to acquire NSC-conditioned medium. Sixty adult Wistar rats were randomly divided into four groups （n=15 in each）： NSC graft, NSC medium, graft control and medium control groups. Microsurgical transection of the spinal cord was performed in all the rats at the T11. The NSC graft group received stereotaxic injections of NSCs suspension into both the spinal cord stumps immediately after transection; graft control group received DMEM injection. In NSC medium group, NSC-conditioned medium was administered into the spinal cord every week; NSC culture medium was administered to the medium control group. Hindlimb motor function was assessed using the BBB Locomotor Rating Scale. Regeneration of biotin dextran amine （BDA） labeled corticospinal tract was assessed. Differentiation of NSCs and the expression of synaptophysin at the distal end of the injured spinal cord were observed under a confocal microscope. Group comparisons of behavioral data were analyzed with ANOVA. Results NSCs transplantation resulted in extensive growth of corticospinal axons and locomotor recovery in adult rats after complete spinal cord transection, the mean BBB scores reached 12.5 in NSC graft group and 2.5 in graft control group （P〈 0.05）. There was also significant difference in BBB score between the NSC medium （11.7） and medium control groups （3.7, P〈 0.05）. BDA traces regenerated fibers sprouted across the lesion site and entered the caudal part of the spinal cord. Synaptophysin expression coloca

关键词： spinal cord injuries stem cells nerve regeneration

Residual topography and lithospheric isostatic gravity anomaly in the East Asian Continent

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Journal of Earth Science 2024年

作者： Pengyu liu Zhengwang Hu Qing liang Bo Chen Chao Chen Hubei Subsurface Multi-scale Imaging Key Laboratory， School of Geophysics and Geomatics， China University of Geosciences School of Geosciences and Info-Physics， Central South University

The topography of the Earth is a crucial component for investigating dynamic topography and lithosphere–upper mantle dynamics. Dynamic topography， caused by geodynamic processes， significantly shapes Earth's current surface. Residual topography serves as an indicator of this dynamic topography. To determine residual topography， one must first obtain isostatic topography. In this study， we propose a new calculation method for isostatic topography based on the Airy-Heiskanen lithospheric isostasy model. The method is applied to obtain the residual topography map of the East Asian Continent (EAC) using the global relief model ETOPO1， the latest global crustal model ECM1， and the global seismic tomography model SL2013sv. The short-wavelength components of residual topography provide more detailed information about non-isostatic topography caused by lithospheric tectonic movements as compared to the long-wavelength components. The isostatic gravity anomaly based on the proposed lithospheric isostasy model presents some new insights into the dynamic characteristics of the lithosphere in the EAC.

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Interaction between Breathers and Rogue Waves in a Nonlinear Optical Fiber

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Chinese Physics Letters 2018年第2期35卷 1-5页

作者： Xiang-Shu liu Li-Chen Zhao liang Duan Peng Gao Zhan-Ying Yang Wen-Li Yang School of Physics Northwest UniversityXi'an 710069 Faculty of Science Qinzhou UniversityQinzhou 535000 Shaanxi Key Laboratory for Theoretical Physics Frontiers Xi'an 710069 Institute of Modern Physics Northwest UniversityXi'an 710069

We study the interaction between breather and N-order rogue waves in a nonlinear optical *** impacts of the relative phase and the interaction distance between breathers and rogue waves are discussed in ***,the breather can reduce the maximum hump value of high-order rogue waves greatly in the eases of nonzero relative phase or nonzero interaction *** characteristic of exclusion between breathers and rogue waves is described qualitatively in the situation of different interaction distances,which can be used to change the temporal-spatial distribution of rogue *** interaction properties are characterized by the trajectory of localized waves'valleys and *** is shown that the interaction changes the dynamical evolution trajectory of rogue waves and *** results provide some possible ways to control high-order rogue waves.

关键词： Optical fibers

Quantitative parameters in novel spectral computed tomography:Assessment of Ki-67 expression in patients with gastric adenocarcinoma

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World Journal of Gastroenterology 2023年第10期29卷 1602-1613页

作者： Li-Ting Mao Wei-Cui Chen Jian-Ye Lu Han-liang Zhang Yong-Song Ye Yu Zhang Bo liu Wei-Wei Deng Xian liu Department of Radiology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Pathology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Scientific Research Clinical&Technical SupportPhilips Healthcare ChinaShanghai 200040China

BACKGROUND The level of Ki-67 expression has served as a prognostic factor in gastric *** quantitative parameters based on the novel dual-layer spectral detector computed tomography(DLSDCT)in discriminating the Ki-67 expression status are *** To investigate the diagnostic ability of DLSDCT-derived parameters for Ki-67 expression status in gastric carcinoma(GC).METHODS Dual-phase enhanced abdominal DLSDCT was performed preoperatively in 108 patients with gastric *** tumor monoenergetic CT attenuation value at 40-100 kilo electron volt(kev),the slope of the spectral curve(λ_(HU)),iodine concentration(IC),normalized IC(nIC),effective atomic number(Z^(eff))and normalized Z^(eff)(nZ^(eff))in the arterial phase(AP)and venous phase(VP)were retrospectively compared between patients with low and high Ki-67 expression in gastric ***’s correlation coefficient was used to analyze the association between the above parameters and Ki-67 expression *** operating characteristic(ROC)curve analysis was performed to compare the diagnostic efficacy of the statistically significant parameters between two *** Thirty-seven and 71 patients were classified as having low and high Ki-67 expression,***_(40 kev-VP),CT_(70 kev-VP),CT_(100 kev-VP),and Z^(eff)-related parameters were significantly higher,but IC-related parameters were lower in the group with low Ki-67 expression status than the group with high Ki-67 expression status,and other analyzed parameters showed no statistical difference between the two ***’s correlation analysis showed that CT_(40 kev-VP),CT_(70 kev-VP),CT_(100 kev-VP),Z^(eff),and n Z^(eff) exhibited a negative correlation with Ki-67 status,whereas IC and nIC had positive correlation with Ki-67 *** ROC analysis demonstrated that the multi-variable model of spectral parameters performed well in identifying the Ki-67 status[area under the curve(AUC)=0.967;sensitivity 9

关键词： Spectral computer tomography Quantitative parameters Gastric carcinoma Iodine concentration Effective atomic number Ki-67 expression

Hot-band absorption of indocyanine green for advanced anti-stokes fluorescence bioimaging

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Light(Science & Applications) 2021年第10期10卷 1877-1888页

作者： Jing Zhou Xiaoxiao Fan Di Wu Jie liu Yuhuang Zhang Zikang Ye Dingwei Xue Mubin He liang Zhu Zhe Feng Andrey N.Kuzmin Wen liu Paras N.Prasad Jun Qian State Key Laboratory of Modern Optical Instrumentations Centre for Optical and Electromagnetic ResearchCollege of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZhejiang UniversityHangzhou 310058China Sir Run-Run Shaw Hospital School of MedicineZhejiang UniversityHangzhou 310016China Key Laboratory of Flexible Electronics(KLOFE)Institute of Advanced Materials(IAM) Nanjing Tech University(Nanjing Tech)Nanjing 211800China Department of Chemistry Zhejiang UniversityHangzhou 310058China Interdisciplinary Institute of Neuroscience and Technology(ZIINT) College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhou 310027China Institute for Lasers Photonicsand BiophotonicsDepartment of ChemistryUniversity at BuffaloState University of New YorkBuffaloNY 14260USA Key Laboratory of Optical Information Detection and Display Technology of Zhejiang Zhejiang Normal UniversityJinhua 321004China

Bright anti-Stokes fluorescence(ASF)in the first near-infrared spectral region(NIR-I,800 nm–900 nm)under the excitation of a 915 nm continuous wave(CW)laser,is observed in Indocyanine Green(ICG),a dye approved by the Food and Drug Administration for clinical *** dependence of fluorescence intensity on excitation light power and temperature,together with fluorescence lifetime measurement,establish this ASF to be originated from absorption from a thermally excited vibrational level(hot-band absorption),as shown in our experiments,which is stronger than the upconversion fluorescence from widely-used rare-earth ion doped *** test the utility of this ASF NIR-I probe for advanced bioimaging,we successively apply it for biothermal sensing,cerebral blood vessel tomography and blood stream ***,in combination with L1057 nanoparticles,which absorb the ASF of ICG and emit beyond 1100 nm,these two probes generate multi-mode images in two fluorescent channels under the excitation of a single 915 nm CW *** channel is used to monitor two overlapping organs,urinary system&blood vessel of a live mouse,while the other shows urinary system *** in intraoperative real-time monitoring,such multi-mode imaging method can be beneficial for visual guiding in anatomy of the urinary system to avoid any accidental injury to the surrounding blood vessels during surgery.

关键词： absorption excitation anatomy

应用序列二次规划的波达方向与多普勒频率联合估计

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光学精密工程 2015年第7期23卷 2079-2085页

作者：单泽彪石要武单泽涛刘小松吉林大学通信工程学院吉林长春130022 诺博橡胶制品有限公司河北保定072550

为了快速准确地联合估计阵列信号波达方向(DOA)与多普勒频率,提出了将序列二次规划(SQP)应用于最大似然函数优化的联合谱估计算法。该方法利用空时信号模型通过Hankel矩阵构造出阵列流型中包含DOA与多普勒频率信息的广义天线阵模型,并... 详细信息

为了快速准确地联合估计阵列信号波达方向(DOA)与多普勒频率,提出了将序列二次规划(SQP)应用于最大似然函数优化的联合谱估计算法。该方法利用空时信号模型通过Hankel矩阵构造出阵列流型中包含DOA与多普勒频率信息的广义天线阵模型,并推导出其最大似然函数,从而将参数估计问题转化为非线性函数优化问题。然后,将SQP方法应用于似然函数的优化求解中,得到DOA与多普勒频率的估计值。最后应用SQP方法、微分进化法、遗传算法和量子粒子群算法分别进行了优化的仿真对比实验。结果表明:提出的算法具有寻优时间短,估计精度高,参数自动配对等特点,在信噪比为0dB时估计两个目标信号源的DOA与多普勒频率的均方根误差分别为0.263 6°和0.007 6rad,基本达到了阵列信号处理中参数联合估计方法的设计要求。

关键词：空时信号模型波达方向多普勒频率序列二次规划最大似然估计

Transporters(OATs and OATPs) contribute to illustrate the mechanism of medicinal compatibility of ingredients with different properties in yuanhuzhitong prescription

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Acta Pharmaceutica Sinica B 2020年第9期10卷 1646-1657页

作者： ze Wang Haihua Shang Yazhuo Li Chen Zhang Yan Dong Tao Cui Hongbing Zhang Xiaoyan Ci Xiulin Yi Tiejun Zhang Fengying Yan Yaping Zhang Xing Huang Weidang Wu Changxiao liu Tianjin University of Traditional Chinese Medicine Tianjin 300193China Biotechnology Center Tianjin Institute of Pharmaceutical Research Co.Ltd.Tianjin 300193China Tianjin Institute of Pharmaceutical Research New Drug Evaluation Research Co.Ltd. State Key Laboratory of Drug Release Technology and PharmacokineticsTianjin 300031China Chu Hsien-I Memorial Hospital Tianjin Medical UniversityTianjin 300134China Shenyang Pharmaceutical University Shenyang 110016China Anhui Medical University Hefei 230032China Emergency Department Zhongshan HospitalFudan UniversityShanghai 200032China Hefei Tianhui Hatching Technology Co.Ltd. Hefei 230032China

Various medicinal ingredients with different tastes are combined according to the theory of compatibility in Chinese materia medica to achieve a better efficacy,while the mechanism was not very ***,the authors studied the interaction between ingredients and human transporters such as the kidney transporters OAT1 and OAT3,the liver transporters OATP1 B1 and OATP1 B3,and the intestine transporter OATP2 B1 to discern the compatibility mechanism of ingredients with different tastes in the Yuanhuzhitong preparation(YHP)comprising Corydalis yanhusuo(CYH)and Angelica dahurica(AD),which could relieve pain by restraining the central *** results show that tetrahydropalmatine(TDE),the major component of CYH,could be transported by OAT3 into kidney,OATP1 B1 and OATP1 B3 into liver,while imperatorin(IPT)and isoimperatorin(ISP),the two key components of AD,and AD extract showed strong inhibition to OAT1 and ***’s more,AD extract also exerted strongly inhibition to human transporters OATP1 B1 and OATP1 *** was also detected that IPT,ISP,and AD extract significantly downregulated the expression of Oatplal,Oafp1 a4,and Oatp1 b2 of liver in *** in vivo results show that the concentration of TDE in liver and kidney significantly decreased,while the TDE concentration in blood and brain were both significantly enhanced in the presence of IPT,ISP,and AD *** results suggest that the ingredients in AD with pungent taste could enhance the exposure of TDE in blood and brain by inhibiting the uptake of TDE in liver and *** is to say,TDE with bitter taste could"flood up"into the central nervous system to play its therapeutic effect by the cut-off of that into liver and kidney in the presence of ingredients within *** paper not only proves the meridian distribution of CYH in liver and kidney with the role of OAT3,OATP1 B1,and OATP1 B3,but also illustrates how to improve the efficacy of CYH by reasonable compatibility with *** study may offer

关键词： Transporters Drug-drug interaction Yuanhuzhitong prescription OAT1 OAT3 OATP1B1 OATP1B3 OATP2B1

A NOVEL METHOD TO REALIze COMPRESSED VIDEO SUPER-RESOLUTION RECONSTRUCTION

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Journal of Electronics(China) 2006年第2期23卷 310-313页

作者： Zhou liang liu Feng Zhu Xiuchang Information Industry Ministry and Jiangsu Province Key Lab of lmage Processing and Image Communication Nanjing University of Posts and Communications Nanjing 210003 China

This letter proposes a novel method of compressed video super-resolution reconstruction based on MAP-POCS (Maximum Posterior Probability-Projection Onto Convex Set). At first assuming the high-resolution model subject to Poisson-Markov distribution, then constructing the projecting convex based on MAP. According to the characteristics of compressed video, two different convexes are constructed based on integrating the inter-frame and intra-frame information in the wavelet-domain. The results of the experiment demonstrate that the new method not only outperforms the traditional algorithms on the aspects of PSNR (Peak Signal-to-Noise Ratio), MSE (Mean Square Error) and reconstruction vision effect, but also has the advantages of rapid convergence and easy extension.

关键词： Super-resolution Compressed video Image reconstruction MAP-POCS

In situ grown Fe_(3)O_(4)particle on stainless steel:A highly efficient electrocatalyst for nitrate reduction to ammonia

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Nano Research 2022年第4期15卷 3050-3055页

作者： Xiaoya Fan Lisi Xie Jie liang Yuchun Ren Longcheng Zhang Luchao Yue Tingshuai Li Yonglan Luo Na Li Bo Tang Yang liu Shuyan Gao Abdulmohsen Ali Alshehri Qian liu Qingquan Kong Xuping Sun Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China Institute for Advanced Study Chengdu UniversityChengdu 610106China College of Chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinan 250014China School of Materials Science and Engineering Henan Normal UniversityXinxiang 453007China Chemistry Department Faculty of ScienceKing Abdulaziz UniversityP.O.Box 80203Jeddah 21589Saudi Arabia

NH_(3)is an essential feedstock for fertilizer ***-scale NH_(3)synthesis mostly relies on the Haber-Bosch method,however,which suffers from massive CO_(2) emission and high energy *** NO_(3)-reduction is an attractive substitute to the Haber-Bosch method for synthesizing NH_(3)under mild *** this reaction will produce a variety of products,it highly desires efficient and selective electrocatalyst for NH_(3)***,we report in situ grown Fe_(3)O_(4)particle on stainless steel(Fe_(3)O_(4)/SS)as a high-efficiency electrocatalyst for NO_(3)^(-)reduction to NH_(3).In 0.1 M NaOH with 0.1 M NaNO_(3),such Fe_(3)O_(4)/SS reaches a remarkable Faradaic efficiency of 91.5%and a high NH_(3)yield of 10,145μg·h^(-1)·cm^(-2)at-0.5 V *** hydrogen electrode(RHE).Furthermore,it owns robust structural and electrochemical *** work provides useful guidelines to expand the scope of metallic oxide electrocatalysts for NH_(3)*** catalytic mechanism is uncovered and discussed further by theoretical calculations.

关键词： Fe_(3)O_(4)particle NO_(3)–reduction reaction NH_(3)synthesis electrocatalysis