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气动干扰对串列双幅类流线形断面颤振的影响

振动与冲击 2014年第8期33卷 161-164,191页

作者：刘小兵杨群刘志文石家庄铁道大学风工程研究中心石家庄050043 湖南大学风工程试验研究中心长沙410082 石家庄铁道大学土木工程学院石家庄050043

针对串列双幅类流线形断面,在均匀流场中进行了一系列的颤振稳定性风洞试验,并将试验结果与单幅类流线形断面的试验结果进行了对比。研究结果显示:气动干扰降低了双幅类流线形断面的颤振临界风速,间距越小,降低幅度越大;气动干扰增大了... 详细信息

针对串列双幅类流线形断面,在均匀流场中进行了一系列的颤振稳定性风洞试验,并将试验结果与单幅类流线形断面的试验结果进行了对比。研究结果显示:气动干扰降低了双幅类流线形断面的颤振临界风速,间距越小,降低幅度越大;气动干扰增大了双幅类流线形断面的颤振频率,间距越小,增大幅度越大;与单幅类流线形断面相比,气动干扰使双幅类流线形断面的软颤振特性更明显。

关键词：气动干扰串列双幅类流线形断面颤振风洞试验

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水环境生态补偿法律机制探讨

江苏行政学院学报 2016年第2期 122-129页

作者：刘小冰方晴南京工业大学法学院南京211816

目前,我国水环境生态补偿法律机制还存在补偿主体与受偿主体单一且不具体、补偿方式单一且不灵活、补偿标准和补偿核算不合理、补偿资金来源单一且监管不善、补偿执行机关的工作效率不高等问题。为此,需要细化补偿主体与受偿主体、设立... 详细信息

目前,我国水环境生态补偿法律机制还存在补偿主体与受偿主体单一且不具体、补偿方式单一且不灵活、补偿标准和补偿核算不合理、补偿资金来源单一且监管不善、补偿执行机关的工作效率不高等问题。为此,需要细化补偿主体与受偿主体、设立多元化的补偿方式、完善补偿标准及补偿核算方式、拓展补偿资金的来源并强化监管措施、设立水环境生态补偿的法定公共组织以提高执行工作效率。同时,还要在制度层面对水环境生态补偿机制提供有效的立法、执法、司法与守法上的保障。

关键词：水环境生态补偿法律机制

Chatter suppression techniques in milling processes:A state of the art review

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Chinese Journal of Aeronautics 2024年第7期37卷 1-23页

作者： Zhenmin LI Qinghua SONG Peijian JIN Zhanqiang liu bing WANG Haifeng MA Key Laboratory of High Efficiency and Clean Mechanical Manufacture Ministry of EducationSchool of Mechanical EngineeringShandong UniversityJinan 250061China National Demonstration Center for Experimental Mechanical Engineering Education Shandong UniversityJinan 250061China

Chatter in the machining system can result in a decrease in tool life,poor surface finish,conservative cutting parameters,*** many review papers promoting the understanding and research of this area,chatter suppression techniques are generally discussed within limited pages in the framework of comprehensive chatter-related *** recent years,the developments of smart materials,advanced sensing techniques,and more effective control strategies have led to some new progress in chatter ***,the widely used thin-walled parts present more and more severe machining challenges in their milling *** the above deficiencies,this paper summarizes the current state of the art in milling chatter *** classifications of chatter suppression techniques are proposed according to the working principle and control *** on the new classified framework,the mechanism and comparisons of different chatter suppression strategies are ***,the current challenges and potential tendencies of milling chatter suppression techniques are ***,integration,compactness,adaptability to workpiece geometry,and the collaboration of multiple control methods are predicted to be important trends in the future.

关键词： Active control Chatter suppression Damping Milling Regenerative effect

Three positive charge nonapoptotic-induced photosensitizer with excellent water solubility for tumor therapy

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Chinese Chemical Letters 2024年第8期35卷 205-210页

作者： Zhe Li Ping-Zhao Liang Li Xu Fei-Yu Yang Tian-bing Ren Lin Yuan Xia Yin xiao-bing Zhang State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

Photodynamic therapy(PDT)has emerged as a significant cancer therapy ***,cation-based organic small molecule aggregation-induced emission(AIE)photosensitizers(PSs)attract the wide atten-tion of many scientists,due to improved reactive oxygen species(ROS)production after ***,such PSs tend to localize only the mitochondria,limiting the death way of tumor cells(usu-ally apoptosis)during PDT process,which may affect the therapeutic effect under some ***,we designed a novel water-soluble three positive charge PS,TPAN-18F,which could be distributed uniformly in cell cytoplasm and had distribution in different sub-organelles(mitochondria,endoplasmic reticulum,lysosome).The experimental results showed that TPAN-18F-based PDT process can not only disrupt mitochondrial functions(reducing ATP production and destroying mitochondrial membrane po-tential),but also elevate the intracellular lipid peroxides(LPOs)level,which evoke the non-apoptotic death manner of tumor ***,in vivo studies showed that TPAN-18F-based PDT could effectively inhibit tumor ***,we believe that the construction of TPAN-18F is suggestive for tumor non-apoptotic therapy.

关键词： Water-soluble Three positive charge Photosensitizer Nonapoptotic Tumor therapy

Methods,Mechanisms,and Application Prospects for Enhancing Extracellular Vesicle Uptake

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Current Medical Science 2024年第2期44卷 247-260页

作者： Ying-peng XU Tao JIANG xiao-fan YANG Zhen-bing CHEN Department of Hand Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Extracellular vesicles(EVs)are considered to be a new generation of bioinspired nanoscale drug delivery systems due to their low immunogenicity,natural functionality,and excellent ***,limitations such as low uptake efficiency,insufficient production,and inhomogeneous performance undermine their *** address these issues,numerous researchers have put forward various methods and applications for enhancing EV uptake in recent *** this review,we introduce various methods for the cellular uptake of EVs and summarize recent advances on the methods and mechanisms for enhancing EV *** addition,we provide further understanding regarding enhancing EV uptake and put forward prospects and challenges for the development of EV-based therapy in the future.

关键词： extracellular vesicles exosomes extracellular vesicle uptake extracellular vesiclebased therapy

Construction and performance test of charged particle detector array for MATE

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Nuclear Science and Techniques 2024年第8期35卷 92-100页

作者： xiao‑Bin Li Long‑Hui Ru Zhi‑Chao Zhang bing‑Feng Lv Ning‑Tao Zhang Jin‑Long Zhang Chen‑Gui Lu bing‑Shui Gao Jun‑bing Ma Fu‑Shuai Shi Satoru Terashima xiao‑Dong Xu Zhen Bai Shi‑Wei Xu Yan‑Yun Yang Hooi‑Jin Ong xiao‑Dong Tang Institute of Modern Physics(IMP) Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Research Center for Nuclear Physics Osaka UniversityIbarakiOsaka 567‑0047Japan RIKEN Nishina Center WakoSaitama 351‑0198Japan Joint Department for Nuclear Physics Lanzhou University and Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China

A charged particle array named MATE-PA,which serves as an auxiliary detector system for a Multi-purpose Active-target Time projection chamber used in nuclear astrophysical and exotic beam Experiments(MATE),was *** array comprised of 20 single-sided strip-silicon detectors covering approximately 10%of the solid *** detectors facilitated the detection of reaction-induced charged particles that penetrate the active volume of the *** performance of MATE-PA has been experimentally studied using an alpha source and a 36-MeV 14 N beam injected into the MATE chamber on the radioactive ion beam line in Lanzhou(RIBLL).The chamber was filled with a gas mixture of 95%4 He and 5%CO_(2) at a pressure of 500 *** results indicated good separation of light-charged particles using the forward double-layer silicon detectors of *** energy resolution of the Si detectors was deduced to be approximately 1%(σ)for an energy loss of approximately 10 MeV caused by theα*** inclusion of MATE-PA improves particle identification and increases the dynamic range of the kinetic energy of charged particles,particularly that of theαparticles,up to approximately 15 MeV.

关键词： Silicon detector array Active target Time projection chamber

Predictive effect of lipopolysaccharide-stimulated inflammatory cytokines on symptoms of generalized anxiety disorder

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World Journal of Psychiatry 2024年第9期14卷 1308-1318页

作者： Wen-Yuan Wang Na liu xiao-xiao Qi bing Han Jing-Na Sun Zheng-Li Chen Ming-Wei Wang Yan-Yong Wang Department of Neurology The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Neurology Hebei HospitalXuanwu HospitalCapital Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Neurological Examination at Treatment Center The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Clinical Laboratory The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Generalized anxiety disorder(GAD)is a relatively common mental ***,inflammation,an important factor for the development of depression,has attracted increasing *** studies have shown that inflammatory cytokines can affect the pathophysiological processes of several nervous system *** hypothesized that there is a correlation between the levels of lipopolysaccharide(LPS)-stimulated inflammatory cytokines and the clinical symptoms of *** To investigate the predictive effect of LPS-stimulated inflammatory cytokines on symptoms of *** This was a cross-sectional study in which 89 patients with GAD diagnosed at The First Hospital of Hebei Medical University from January 2022 to December 2022 and 70 individuals without anxiety and depression(controls)during the same period were *** venous blood was collected from all the subjects in heparin tubes,and another 3 ml of blood was supplemented with LPS(10 ng/ml).The plasma levels of 12 cytokines[Interleukin(IL)-1β,IL-2,IL-4,IL-5,IL-6,IL-8,IL-10,tumor necrosis factor(TNF)-α,interferon(IFN)-γ,IL-17A,IL-12p70,and IFN-α]were *** Post-LPS stimulation,the levels of IL-1β,IL-6,IL-8,IL-10,and TNF-αin both the control and GAD groups were significantly elevated above those in the nonstimulated groups,with IL-6 and IL-8 showing marked *** in IL-8 and TNF-αwere statistically significant in the GAD group(P<0.05).IL-1β,IL-6,IL-8,IL-10,and TNF-αwere found to be significantly correlated with Hamilton Anxiety Rating Scale(HAMA)scores(P<0.05).A negative correlation was observed between IL-10 levels and HAMA *** analysis revealed that TNF-αwas associated with mental anxiety,whereas IL-1β,IL-8,and IL-10 were associated with physical anxiety symptoms,with IL-10 showing a negative correlation with physical ***-6 was associated with both mental and physical aspects of *** The physical symptoms of GAD are related to infla

关键词： Lipopolysaccharide Cytokine Generalized anxiety disorder Inflammatory cytokines Anxiety

Non-contact and full-field online monitoring of curing temperature during the in-situ heating process based on deep learning

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Advances in Manufacturing 2024年第1期12卷 167-176页

作者： Qiang-Qiang liu Shu-Ting liu Ying-Guang Li Xu liu xiao-Zhong Hao College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing210016People’s Republic of China School of Mechanical and Power Engineering Nanjing Tech UniversityNanjing211816People’s Republic of China

Online monitoring of the curing temperature field is essential to improving the quality and efficiency of the manufacturing process of composite *** embedded sensor-based technologies have difficulty monitoring the full temperature field or have to introduce heterogeneous items that could have an undesired impact on the *** this paper,a non-contact,full-field monitoring method based on deep learning that predicts the internal temperature field of composite parts in real time using surface temperature measurements of auxiliary materials is *** the proposed method,an average temperature monitoring accuracy of 97%is achieved in various heating *** addition,this method also demonstrates satisfying feasibility when a stronger thermal barrier covers the *** method was experimentally validated during the self-resistance electric heating process,in which the monitoring accuracy reached 93.1%.This method can potentially be applied to automated manufacturing and process control in the composites industry.

关键词： Online monitoring Curing temperature field Deep learning(DL) In-situ heating

Cigarette Use and Secondhand Smoke Exposure Among Secondary School Students—China,2023

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China CDC weekly 2024年第22期6卷 509-515页

作者： Xinying Zeng Shiwei liu Lin xiao Tobacco Control Office Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?In 2021,the prevalence of experimental and current cigarette use among secondary school students in China stood at 16.7%and 4.7%,***,39.9%of these students were exposed to secondhand smoke at *** is added by this report?In comparison to 2021,the prevalence of current cigarette use remained unchanged at 4.2%in 2023,whereas experimental use declined to 13.7%.Notably,rates were significantly higher among vocational senior high school(VSHS)students relative to their peers in senior high school(SHS)and junior high school(JHS).Furthermore,exposure to secondhand smoke in schools decreased to 35.4%in 2023 from previously recorded levels,with more pronounced reductions observed in JHS and SHS populations and no notable change among VSHS *** are the implications for public health practice?Targeted tobacco control policies are imperative for secondary school students,including the establishment of smoke-free school ***,it is crucial to pay close attention to the needs of VSHS students.

关键词： smoke unchanged senior