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Science China Chemistry 2025年

作者： Haoyue liang Xingguo Zhong Guxin Huang Wenpan liu Yao liu Shuhao Wang Deyu Wang Hao liu Hao Wang Tianyou Zhai Huiqiao Li State Key Laboratory of Materials Processing and Die & Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology Shenzhen Research Institute of Huazhong University of Science and Technology Key Laboratory of Optoelectronic Chemical Materials and Devices (Ministry of Education) School of Optoelectronic Materials &Technology Jianghan University Centre for Clean Energy Technology Faculty of Science University of Technology Sydney Yichang Brunp Recycling Technology Co. Ltd.

Li3VO4has been a promising insertion anode material for Li-ion batteries,which has high theoretical capacity (up to～600 mAh g-1) and safe Li insertion voltage （0.5–1 V ***/Li+）.However,the low initial Coulombic efficiency （ICE） has always been the bottleneck limiting its ***,we propose a facile pre-lithiation method to controllably elevate the ICE by the post-treatment of the prepared Li3VO4composite electrode based on an immersion *** this process,the whole electrode was immersed in the liquid Li source,via which the ICE of the Li3VO4electrode can be controllably elevated from 80%to over 100%within 5 min of *** than the traditional powder treatment for pre-lithiation,this process we proposed minimizes the impact of pre-lithiation on the battery assembly ***,we further investigated the effect of this pre-lithiation process on the functional components in the *** the first time the ICE of Li3VO4electrode was elevated to 100%.As a result,the initial reversible capacity of LiFePO4||Li3VO4full cell was improved from 44.0 to146.3 m Ah g-1,demonstrating the feasibility and great potential of the process.

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Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

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Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang Dexiang liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao yan Song Yahong Cheng Tong Li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

不同产地浮萍中5种黄酮成分量及抗氧化活性的化学模式识别研究

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中草药 2017年第5期48卷 985-990页

作者：蒋祥亮刘聪燕陈彦黄萌萌王理想李萍安徽中医药大学安徽合肥230012 江苏省中医药研究院中药组分与微生态研究中心江苏南京210028

目的测定不同产地浮萍Spirodela polyrriza中5个黄酮类成分的量,并对其抗氧化活性进行评价。方法采用HPLC法,以乙腈-0.1%甲酸为流动相测定8个产地17批浮萍药材中荭草素、牡荆素、木犀草苷、大波斯菊苷、木犀草素的量;采用DPPH清除率法... 详细信息

目的测定不同产地浮萍Spirodela polyrriza中5个黄酮类成分的量,并对其抗氧化活性进行评价。方法采用HPLC法,以乙腈-0.1%甲酸为流动相测定8个产地17批浮萍药材中荭草素、牡荆素、木犀草苷、大波斯菊苷、木犀草素的量;采用DPPH清除率法比较不同产地浮萍的抗氧化活性,并结合聚类分析和主成分分析等化学模式识别技术对浮萍质量进行评价。结果不同产地浮萍中5个黄酮类成分量存在一定差异,聚类分析和主成分分析均可将不同产地浮萍分为3类,且分类结果一致。其中陕西和山西产地的浮萍中荭草素、牡荆素、木犀草苷的量均较其他产地明显偏高;相关性分析表明,氧化清除率与黄酮类成分量呈显著正相关。结论陕西和山西产地的浮萍黄酮类成分量高,抗氧化能力较强。所建立的分析方法稳定可靠,可为浮萍药材的产地识别和质量控制提供参考。

关键词：浮萍黄酮类荭草素牡荆素木犀草苷大波斯菊苷木犀草素聚类分析主成分分析抗氧化活性

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超临界机组隔膜泵膜片的有限元分析

汽轮机技术 2020年第2期62卷 129-131页

作者：孟召军高涵刘晶晶刘彦良沈阳工程学院能源与动力学院沈阳110136 沈阳工程学院研究生院沈阳110136

选取隔膜泵膜片作为研究对象,利用ANSYS软件对隔膜片的应力与形变进行仿真,对隔膜泵膜片的破裂原因进行分析,分析结果表明,膜片的固定处内缘和中心区域外缘是隔膜片应力和形变量较大的两处危险部位。计算的结果对改进隔膜泵膜片的结构,... 详细信息

选取隔膜泵膜片作为研究对象,利用ANSYS软件对隔膜片的应力与形变进行仿真,对隔膜泵膜片的破裂原因进行分析,分析结果表明,膜片的固定处内缘和中心区域外缘是隔膜片应力和形变量较大的两处危险部位。计算的结果对改进隔膜泵膜片的结构,设计出具有更高可靠性的新型隔膜片提供了指导方向。

关键词：隔膜泵膜片有限元分析

孟加拉湾SST季节循环双峰结构的热收支诊断

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海洋科学进展 2013年第4期31卷 429-437页

作者：刘延亮于卫东李奎平国家海洋局第一海洋研究所山东青岛266061 国家海洋局第一海洋研究所海洋与气候研究中心山东青岛266061

孟加拉湾海表温度(SST)存在显著的季节变化,它在春季和秋季出现两个峰值,而且春季峰值要高于秋季。本研究利用孟加拉湾中部的浮标观测资料,结合卫星遥感资料对2009年孟加拉湾混合层热收支进行诊断分析,揭示了两个SST峰值的形成机制及不... 详细信息

孟加拉湾海表温度(SST)存在显著的季节变化,它在春季和秋季出现两个峰值,而且春季峰值要高于秋季。本研究利用孟加拉湾中部的浮标观测资料,结合卫星遥感资料对2009年孟加拉湾混合层热收支进行诊断分析,揭示了两个SST峰值的形成机制及不对称的原因。结果表明:春、秋季孟加拉湾增暖过程呈现不同机制,春季增暖主要是热通量项的强加热效应的造成的,而秋季增暖是热通量项和温度平流输运共同加热造成的。SST在春季和秋季的峰值不对称主要是由热通量的加热效应不对称所造成的。对热通量项的进一步分析表明,春、秋季被混合层吸收的热通量和混合层深度的不对称共同造成了热通量加热效应的不对称。

关键词：孟加拉湾热通量双峰不对称

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用苹果饲养桃小食心虫的方法

昆虫知识 2006年第4期43卷 571-573页

作者：张月亮慕卫赵德刘彦良杨连来山东农业大学植物保护学院山东泰安271018

报道用苹果饲养桃小食心虫CarposinaniponensisWalsingham的方法。在温度(25±1)℃、RH60%～70%的条件下,着重研究不同日光照时数对该虫一些主要生物学特性的影响。结果表明:以日光照时数15h为最佳,在上述条件下连续饲养7代未发现退化... 详细信息

报道用苹果饲养桃小食心虫CarposinaniponensisWalsingham的方法。在温度(25±1)℃、RH60%～70%的条件下,着重研究不同日光照时数对该虫一些主要生物学特性的影响。结果表明:以日光照时数15h为最佳,在上述条件下连续饲养7代未发现退化现象。与人工饲料饲养比较,该法饲养所获得的幼虫历期、幼虫脱果率、蛹重、单雌产卵量及孵化率等指标均有所提高,表明该法具有可行性。

关键词：桃小食心虫苹果光照时数滞育

基于ADMCF340的永磁无刷直流电机控制系统设计

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现代电子技术 2011年第16期34卷 198-199,202页

作者：郭姣刘艳良海军大连舰艇学院基础部辽宁大连116018

随着直流无刷电机应用领域的不断扩大,对控制系统的稳定性和实时性提出了更高的要求。以DSP芯片AD-MCF340为控制核心,设计了永磁无刷直流电机的控制系统,并给出了部分硬件电路图和控制软件流程图。该系统利用DSP芯片的快速运算功能和面... 详细信息

随着直流无刷电机应用领域的不断扩大,对控制系统的稳定性和实时性提出了更高的要求。以DSP芯片AD-MCF340为控制核心,设计了永磁无刷直流电机的控制系统,并给出了部分硬件电路图和控制软件流程图。该系统利用DSP芯片的快速运算功能和面向电机控制的专用外围设备,实现了电流、速度的全数字双闭环控制。研究结果表明,该系统稳定可靠,实时性良好,为永磁无刷直流电机的广泛应用提供了一定的理论参考依据和工程实际方法。

关键词：永磁无刷直流电机 DSP控制器 ADMCF340芯片电机控制

问题式教学法在“信号与系统”课程教学中的运用

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电气电子教学学报 2010年第5期32卷 83-85页

作者：郭姣刘艳良海军大连舰艇学院基础部辽宁大连116018

为了进一步培养学生独立思考问题和解决问题的能力,笔者在"信号与系统"课程的教学中采用了问题式教学法。这种教学模式以问题为核心,让学生围绕问题展开学习过程。其学习过程包括创设场景,启动问题,层层剖析,解决问题,达成目标以及最后... 详细信息

为了进一步培养学生独立思考问题和解决问题的能力,笔者在"信号与系统"课程的教学中采用了问题式教学法。这种教学模式以问题为核心,让学生围绕问题展开学习过程。其学习过程包括创设场景,启动问题,层层剖析,解决问题,达成目标以及最后的反思等环节。本文以取样定理的教学为例,阐释了问题式教学法的实施步骤。实践证明该方法有利于提高学生的学习积极性和能动性,有利于培养学生的自主学习能力和逻辑思维能力。

关键词：取样定理问题式教学法信号与系统

T cell interactions with microglia in immune-inflammatory processes of ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1277-1292页

作者： Yuxiao Zheng Zilin Ren Ying liu Juntang yan Congai Chen yanhui He Yuyu Shi Fafeng Cheng Qingguo Wang Changxiang Li Xueqian Wang School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijingChina Library Beijing University of Chinese MedicineBeijingChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

The primary mechanism of secondary injury after cerebral ischemia may be the brain inflammation that emerges after an ischemic stroke,which promotes neuronal death and inhibits nerve tissue *** the first immune cells to be activated after an ischemic stroke,microglia play an important immunomodulatory role in the progression of the *** an ischemic stroke,peripheral blood immune cells(mainly T cells)are recruited to the central nervous system by chemokines secreted by immune cells in the brain,where they interact with central nervous system cells(mainly microglia)to trigger a secondary neuroimmune *** review summarizes the interactions between T cells and microglia in the immune-inflammatory processes of ischemic *** found that,during ischemic stroke,T cells and microglia demonstrate a more pronounced synergistic ***1,Th17,and M1 microglia can co-secrete proinflammatory factors,such as interferon-γ,tumor necrosis factor-α,and interleukin-1β,to promote neuroinflammation and exacerbate brain ***2,Treg,and M2 microglia jointly secrete anti-inflammatory factors,such as interleukin-4,interleukin-10,and transforming growth factor-β,to inhibit the progression of neuroinflammation,as well as growth factors such as brain-derived neurotrophic factor to promote nerve regeneration and repair brain *** interactions between microglia and T cells influence the direction of the subsequent neuroinflammation,which in turn determines the prognosis of ischemic stroke *** trials have been conducted on the ways to modulate the interactions between T cells and microglia toward anti-inflammatory communication using the immunosuppressant fingolimod or overdosing with Treg cells to promote neural tissue repair and reduce the damage caused by ischemic ***,such studies have been relatively infrequent,and clinical experience is still *** summary,in ischemic stroke,T cell subsets and activated micro

关键词： brain immune inflammation interaction ischemic stroke mechanism microglia neuron secondary injury T cells

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变频器节能性能探讨

煤 2008年第12期17卷 36-37页

作者：刘艳亮秦青潞安集团余吾煤业有限责任公司山西长治046103

变频器具有节能特性,在以"节能降耗,可持续发展"为社会发展主题的今天,具有广泛的使用意义。

关键词：变频器原理节能