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基于智慧工厂的重载铁路机车轮对无人检修工艺线的研究

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自动化应用 2023年第17期64卷 222-224页

作者：温翔宇王鹏刘康宁杨翠平王永刚国能铁路装备有限责任公司沧州机车车辆维修分公司河北沧州061113 北京铁科合力科技有限责任公司北京100082

本文阐述了沧州机车车辆维修分公司重载铁路机车轮对无人检修工艺线的改造方案,以实现降低工人的劳动强度和安全风险,提高铁路机车轮对的检修效率。该方案将实现机车轮对检修线的无人化建设,加快机车检修精益化、智能化、数字化管理进程... 详细信息

本文阐述了沧州机车车辆维修分公司重载铁路机车轮对无人检修工艺线的改造方案,以实现降低工人的劳动强度和安全风险,提高铁路机车轮对的检修效率。该方案将实现机车轮对检修线的无人化建设,加快机车检修精益化、智能化、数字化管理进程,释放机车轮对生产线上因设备所限而设置的岗位,将人力资源向任务更为紧张的基地其他岗位转移,提升基地人力资源利用效率。本文同时描述了新增设备及改造布局,为后续设计提供参考。

关键词：铁路机车轮对检修工艺线智慧工厂

Abundance and characteristics of microplastics in shellfi sh from Jiaozhou Bay,China

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Journal of Oceanology and Limnology 2022年第1期40卷 163-172页

作者： kangning ZHANG Junhua LIANG Tao liu Qingjie LI Mingliang ZHU Shan ZHENG Xiaoxia SUN Jiaozhou Bay National Marine Ecosystem Research Station Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Ecology and Environmental Science Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China Center for Ocean Mega-Science Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

As an emerging pollutant,the presence of microplastics in marine organisms has been concerned *** sh,which are both economically and ecologically important,are of particular *** this study,we investigated the microplastic pollution in wild and farmed oysters(Crassostrea gigas)and clams(Ruditapes philippinarum)in the Jiaozhou Bay,China,for the fi rst *** found the microplastic pollution in shellfi sh in Jiaozhou Bay was at a moderate *** abundance of microplastics in shellfi sh ranged from 0.16 to 12.09 items/g(wet weight,ww)or 1 to 9 items/*** average abundance of the ingested microplastics was 1.21 items/g(or 2.17 items/ind.)in all shellfi sh,1.51 items/g(or 2.00 items/ind.)in clams and 0.92 items/g(or 2.34 items/ind.)in *** abundance of microplastics in clams was signifi cantly higher than that in *** microplastics(92.97%)were fi bers,followed by *** predominant color of the microplastics was black(42.97%),followed by blue,transparent,and *** and polyethylene terephthalate(PET)dominated the microplastic *** to shellfi sh consumption,it can be inferred that the average microplastic consumption through Chinese diet is 1.27×10^(3)items per capita per year.

关键词： microplastics bivalves Jiaozhou Bay risk assessment

Experimental optimization and mathematical modeling of supercritical carbon dioxide extraction of essential oil from Pogostemon cablin

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Chinese Journal of Chemical Engineering 2019年第10期27卷 2407-2417页

作者： kangning Xiong Yun Chen Shuai Shen Department of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510640China

The supercritical carbon dioxide extraction was applied to obtain essential oil from Pogostemon cablin in this *** of extraction parameters including temperature,pressure,extraction time and particle size on extraction yield was investigated,and the response surface methodology with a Box–Behnken Design was used to achieve the optimized extraction *** maximum yield of essential oil was 2.4356%under the conditions of extraction temperature 47°C,pressure 24.5 MPa and extraction time 119 ***,based on the Brunauer–Emmett–Teller theory of adsorption,a mathematical modeling was performed to correlate the measured *** model shows a function relationship between extraction yield and time by a simple equation with three significantly adjustable *** model parameters have been optimized through simulated annealing *** predicted data from the mathematical model show a good agreement with the experimental data of the different extraction parameters.

关键词： Supercritical carbon dioxide extraction Pogostemon cablin Response surface methodology Mathematical modeling Simulated annealing algorithm

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羟基磷灰石基人工骨的研究进展

生物骨科材料与临床研究 2004年第2期1卷 46-48,50页

作者：孙昌孙康宁刘爱红山东大学工程陶瓷山东省重点实验室

目的研究羟基磷灰石基人工骨作为最有发展前途的生物硬组织替代材料之一,在生物医用材料和医学研究领域的应用。方法制备具有良好生物相容性、力学性能、骨诱导性与治疗功能的羟基磷灰石基人工骨,用于人体骨组织的缺失的修复,及相关疾... 详细信息

目的研究羟基磷灰石基人工骨作为最有发展前途的生物硬组织替代材料之一,在生物医用材料和医学研究领域的应用。方法制备具有良好生物相容性、力学性能、骨诱导性与治疗功能的羟基磷灰石基人工骨,用于人体骨组织的缺失的修复,及相关疾病的治疗。结果通过制备性能优良的羟基磷灰石粉体,结合纳米技术、组织工程技术和生物技术将不同材料通过合适的方法组合成羟基磷灰石人工骨,从而获得良好的临床应用性能。结论从临床角度,综合了国内外近十年相关文献的基础上,评述了羟基磷灰石人工骨的研究进展。

关键词：羟基磷灰石人工骨生物材料

Horizontal Mergers between Asymmetric Low-Carbon Manufacturers

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Journal of Systems Science and Systems Engineering 2022年第5期31卷 619-647页

作者： Xiaogang Lin kangning Jin Wenhui Fu Qiang Lin School of Management Guangdong University of Technology Guangzhou 510520China School of Economics and Management South China Normal UniversityGuangzhou 510006China

Mergers have become an important means for low-carbon manufacturers to improve their efficiency and *** paper studies the impact of horizontal mergers between asymmetric low-carbon manufacturers on product diversity,profits,consumer surplus,and the *** the premerger model,we consider two asymmetric manufacturers in terms of market potential that produce two products and compete on prices and carbon *** the postmerger model,the two asymmetric manufacturers merge into one *** merged manufacturer can either continue to produce two products and collude on both products'prices and carbon emissions or enjoy both production and green technology investment cost savings to produce only one *** result suggests that when the merged manufacturer produces two products,the merger does not necessarily lead to higher prices,which stands in sharp contrast to the conventional ***,the merger always benefits the manufacturer but harms *** the merged manufacturer chooses to produce only one product,however,we confirm that the merger can lead to a win-win-win outcome,i.e.,the manufacturer,customers,and environment all become better off if either the production or investment savings are *** conventional wisdom shows that salient costing savings lead to price ***,we show that the merged manufacturer can charge consumers higher prices to provide lower-emission *** addition,we show that improving investment(production)cost savings is more effective for the merged manufacturer if these two cost savings are salient(not salient).Finally,the merged manufacturer should not reduce diversity if these two cost savings are relatively low because the profit and consumer surplus may be simultaneously *** also extend our base model to the case where there exist three manufacturers in the premerger model and the merged firm still operates in a competitive market.

关键词： Game theory asymmetric horizontal merger low-carbon manufacturing price and emission collusions productionand investmentcost synergies

Zuogui pills for myelinolysis in a rat model of experimental autoimmune encephalomyelitis

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Neural Regeneration Research 2011年第9期6卷 666-670页

作者： Yongping Fan Kelong Chen kangning Li Jianping Zhou Yan Shao Hongyan liu WenjingYang Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Beijing Institute of Pharmaceutical Analysis Beijing 100035 China

Zuogui pills have been shown to attenuate the inflammatory reaction in a rat model of experimental autoimmune encephalomyelitis （EAE）. The present study attempted to investigate the pathology underlying the influence of Zuogui pills on myelinolysis in EAE rats. Hematoxylin-eosin and Luxol fast blue staining showed that the myelinolysis foci in the cerebrum, cerebellum, brain stem, and the spinal cord of EAE rats were significantly decreased, along with serum myelin basic protein content following treatment with Zuogui pills.

关键词： Zuogui pill pathology multiple sclerosis experimental autoimmune encephalomyelitis protection treatment neural regeneration

Genesis for Rare Earth Elements Enrichment in the Permian Manganese Deposits in Zunyi, Guizhou Province, SW China

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Acta Geologica Sinica(English Edition) 2020年第1期94卷 90-102页

作者： XU Hai GAO Junbo YANG Ruidong DU Lijuan liu Zhichen CHEN Jun FENG kangning YANG Guanghai College of Resources and Environmental Engineering Guizhou UniversityGuiyang 550025China Key Laboratory of Karst Georesources and Environment Ministry of EducationGuizhou UniversityGuiyang 550025China 102 Geological Team Guizhou Bureau of Exploration and Development of Geology Mineral ResourcesZunyiGuizhou 563003China Institute of Geochemistry Chinese Academy of SciencesGuiyang 550081China

The Zunyi manganese deposits, which formed during the Middle to Late Permian period and are located in northern Guizhou and adjacent areas, are the core area of a series of large-medium scale manganese enrichment minerogenesis in the southern margin and interior of the Yangtze platform, Southern China. This study reports the universal enrichment of rare earth elements(REEs) in Zunyi manganese deposits and examines the enrichment characteristics, metallogenic environment and genesis of REEs. The manganese ore bodies present stratiform or stratoid in shape, hosted in the silicon–mud–limestones of the Late Permian Maokou Formation. The manganese ores generally present lamellar, massive, banded and brecciated structures, and mainly consist of rhodochrosite, ropperite, tetalite, capillitite, as well as contains paragenetic gangue minerals including pyrite, chalcopyrite, rutile, barite, tuffaceous clay rock, etc. The manganese ores have higher ΣREE contents range from 158 to 1138.9 ppm(average 509.54 ppm). In addition, the ΣREE contents of tuffaceous clay rock in ore beds vary from 1032.2 to 1824.5 ppm(average 1396.42 ppm). The REEs from manganese deposits are characterized by La, Ce, Nd and Y enriched, and existing in the form of independent minerals(e.g., monazite and xenotime), indicating Zunyi manganese deposits enriched in light rare earth elements(LREE). The Ceanom ratios(average-0.13) and lithofacies and paleogeography characteristics indicate that Zunyi manganese deposits were formed in a weak oxidation-reduction environment. The(La/Yb)ch, Y/Ho,(La/Nd)N,(Dy/Yb)N, Ce/Ce* and Eu/Eu* values of samples from the Zunyi manganese deposits are 5.53–56.92, 18–39, 1.42–3.15, 0.55–2.20, 0.21–1.76 and 0.48–0.86, respectively, indicating a hydrothermal origin for the manganese mineralization and REEs enrichment. The δ13 CV-PDB(-0.54 to-18.1‰) and δ18 OSMOW(21.6 to 26.0‰) characteristics of manganese ores reveal a mixed source of magmatic and organic matter. Moreover, the manga

关键词： Genesis REEs enrichment Hydrothemal origin Permian manganese deposits Zunyi

基于多重响应的钢渣超高性能混凝土组成优化设计研究

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硅酸盐通报 2021年第9期40卷 3029-3038页

作者：冯元余睿范定强曾敏胡方杰水中和王思雨刘康宁谭珺辉王武峰武汉理工大学硅酸盐建筑材料国家重点实验室武汉430070 武汉理工大学材料科学与工程国际化示范学院武汉430070 武汉理工大学材料科学与工程学院武汉430070 中铁建大桥设计研究院武汉430063 中国铁建股份有限公司桥梁工程实验室武汉430063 中山市武汉理工大学先进工程技术研究院中山528400

为实现生态型超高性能混凝土(UHPC)的组成优化和钢渣利用率的提高,将钢渣粉作为辅助胶凝材料,利用D-最优化设计方法制备生态型UHPC,并建立了UHPC的工作性能与抗压强度预测模型,以进行多重响应分析。最后借助预测模型,以低水泥用量、高... 详细信息

为实现生态型超高性能混凝土(UHPC)的组成优化和钢渣利用率的提高,将钢渣粉作为辅助胶凝材料,利用D-最优化设计方法制备生态型UHPC,并建立了UHPC的工作性能与抗压强度预测模型,以进行多重响应分析。最后借助预测模型,以低水泥用量、高钢渣粉利用率设计出了符合要求的生态型UHPC。结果表明:预测模型构建合理且准确度高,在预测模型中减水剂和硅灰对于工作性能影响程度较大,水泥、减水剂以及钢渣的交互作用对工作性能影响明显,钢渣粉的加入可增强工作性能;硅灰和钢渣粉对抗压强度影响显著,水泥和钢渣粉的交互作用对抗压强度的影响较小,随钢渣粉掺量的增加抗压强度存在最优值;优化的生态型UHPC的配比可以实现钢渣粉替代30%(质量分数)水泥,同时保证抗压强度130 MPa以上,工作性能260 mm以上。

关键词：超高性能混凝土 D-最优化设计方法钢渣粉多重响应分析生态型性能预测

慢性阻塞性肺疾病急性加重期患者痰培养与铁标志物和炎症指标的关系

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中国医学创新 2023年第4期20卷 9-15页

作者：陈森雄刘康宁吴靖升苏群志唐荣德苏健婷广东省江门市新会区中医院广东江门529100 广东省江门市新会区人民医院

目的:探讨慢性阻塞性肺疾病急性加重期(AECOPD)患者痰培养与铁标志物和炎症指标的关系,为AECOPD患者抗感染治疗提供指导。方法:将江门市新会区中医院2020年6月-2022年2月呼吸内科住院部接收的痰培养阳性AECOPD患者122例作为阳性组,同期... 详细信息

目的:探讨慢性阻塞性肺疾病急性加重期(AECOPD)患者痰培养与铁标志物和炎症指标的关系,为AECOPD患者抗感染治疗提供指导。方法:将江门市新会区中医院2020年6月-2022年2月呼吸内科住院部接收的痰培养阳性AECOPD患者122例作为阳性组,同期选择122例痰培养阴性的AECOPD患者作为阴性对照组。采用VITEK2 Compact全自动细菌鉴定仪检测痰培养病原菌类型,采用罗氏Cobasc702全自动生化分析仪检测血清铁(SI)、血清铁蛋白(SF)、转铁蛋白(TRF)、血清淀粉样蛋白A(SAA)和超敏C反应蛋白(hs-CRP);采用万孚免疫荧光层析定量系统FS-113检测降钙素原(PCT);采用Sysmex XS-1000i全自动血细胞分析仪检测白细胞计数(WBC)、中性粒细胞(NE)百分比。结果:122例痰培养阳性AECOPD患者中,细菌感染110例,占比90.16%,其中革兰阳性(G+)菌37例,占比30.33%,革兰阴性(G-)菌73例,占比59.84%,真菌感染12例,占比9.84%;G+菌种以金黄色葡萄球菌及肺炎链球菌为主,G-菌种以鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌为主,真菌感染以白色念珠菌感染为主。真菌感染组及细菌感染组的SI、TRF水平均低于阴性对照组,真菌感染组及细菌感染组的SF水平均高于阴性对照组,差异均有统计学意义(PTRF>SI(PTRF(P<0.05)。结论:AECOPD痰培养阳性患者的SI、TRF低于痰培养阴性的AECOPD患者,SF高于痰培养阴性AECOPD患者;AECOPD患者的SI、TRF、SF与WBC、hs-CRP、PCT、NE及SAA有一定的相关性;SI、SF及TRF可用于早期预测AECOPD患者痰培养阳性结果,而SF及TRF在鉴别AECOPD患者真菌与细菌感染有一定的价值。

关键词：慢性阻塞性肺疾病急性加重期痰培养铁标志物炎症指标预测价值