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Genome-wide association studies for inflorescence type and remontancy in Hydrangea macrophylla

Horticulture Research 2020年第1期7卷 2477-2485页

作者： Xingbo wu lisa w.alexander Oak Ridge Institute of Science and Technology Otis L.Floyd Nursery Research Center472 Cadillac LaneMcMinnvilleTNUSA U.S.Department of Agriculture Agricultural Research ServiceU.S.National ArboretumFloral and Nursery Plants Research UnitOtis L.Floyd Nursery Research Center472 Cadillac LaneMcMinnvilleTNUSA

Inflorescence type and remontancy are two valuable traits in bigleaf hydrangea(Hydrangea macrophylla L.)and both are recessively *** marker-assisted selection(MAS)can greatly reduce the time necessary to breed cultivars with desired *** this study,a genome-wide association study(GwAS)using 5803 single-nucleotide polymorphisms(SNPs)was performed using a panel of 82 bigleaf hydrangea *** SNP locus(Hy_CAPS_Inflo)associated with inflorescence type was identified with general linear model(GLM)and mixed linear model(MLM)methods that explained 65.5%and 36.1%of the phenotypic variations,***-three SNPs associated with remontancy were detected in GLM whereas no SNP was detected in *** SNP locus(Hy_CAPS_Inflo)was converted to a cleaved amplified polymorphic sequence(CAPS)marker that showed absolute identification accuracy(100%)of inflorescence type in a validation panel consisting of eighteen *** *** SNP was investigated in 341 F1 progenies using genotyping by sequencing(GBS)and co-segregated with inflorescence type(χ^(2)=0.12;P=0.73).The SNP was subsequently used for breeding selection using kompetitive allele specific PCR(KASP)*** directions for the use of genomics and MAS in hydrangea breeding improvement are *** results presented in this study provide insights for further research on understanding genetic mechanisms behind inflorescence type and remontancy in *** CAPS and KASP markers developed here will be immediately useful for applying MAS to accelerate breeding improvement in hydrangea.

关键词： breeding cultivar CAPS

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Two haplotype-resolved genomes reveal important flower traits in bigleaf hydrangea(Hydrangea macrophylla)and insights into Asterid evolution

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Horticulture Research 2023年第12期10卷 45-57页

作者： Xingbo wu Sheron A.Simpson Ramey C.Youngblood Xiaofen FLiu Brian E.Scheffler Timothy A.Rinehart lisa w.alexander Amanda M.Hulse-Kemp Department of Environmental Horticulture Tropical Research and Education CenterUniversity of FloridaHomesteadFL 33031United States Genomics and Bioinformatics Research Unit USDA-ARSRaleighNC 27695United States Genomics and Bioinformatics Research Unit USDA-ARSStonevilleMS 38776United States Institute for Genomics Biocomputing and BiotechnologyMississippi State UniversityStarkvilleMS 39762United States Crop Production and Protection USDA-ARSBeltsvilleMD 20705United States Floral and Nursery Plants Research Unit U.S.National ArboretumUSDA-ARSMcMinnvilleTN 37110United States Department of Crop and Soil Sciences North Carolina State UniversityRaleighNC 27695United States

The Hydrangea genus belongs to the Hydrangeaceae family,in the Cornales order of flowering plants,which early diverged among the Asterids,and includes several species that are commonly used ornamental *** them,Hydrangea macrophylla is one of the most valuable species in the nursery trade,yet few genomic resources are available for this crop or closely related Asterid *** high-quality haplotype-resolved reference genomes of hydrangea cultivars‘Veitchii’and‘Endless Summer’[highest quality at 2.22 gigabase pairs(Gb),396 contigs,N5022.8 megabase pairs(Mb)]were assembled and scaffolded into the expected 18 *** the newly developed high-quality reference genomes along with high-quality genomes of other related flowering plants,nuclear data were found to support a single divergence point in the Asterids clade where both the Cornales and Ericales diverged from the *** mapping with an F1 hybrid population demonstrated the power of linkage mapping combined with the new genomic resources to identify the gene for inflorescence shape,CYP78A5 located on chromosome 4,and a novel gene,BAM3 located on chromosome 17,for causing double *** developed in this study will not only help to accelerate hydrangea genetic improvement but also contribute to understanding the largest group of flowering plants,the Asterids.

关键词： Hydra traits resolved

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Testing and modelling of transient adhesion phenomena in rolling-sliding contacts

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Friction 2024年第5期12卷 1016-1027页

作者： Daniel KVARDA alexander MEIERHOFER Klaus SIX Faculty of Mechanical Engineering Brno University of TechnologyBrno61669Czech Republic Virtual Vehicle Research GmbH Graz8010Austria

Transient adhesion effects in rolling–sliding contacts influence all aspects of train–track *** is of high importance specifically when these effects result in critically low adhesion,which poses a risk to traction and braking of railway *** study presents a model that can replicate the transient changes of the coefficient of adhesion with tested water and solid particle *** experimental data for the model are measured using a commercial ball-on-disc *** experimental results showed a liquid reservoir in front of the contact area that slowly reduces in *** observation was used in the modelling approach to divide the calculation into two stages where the reservoir is present and when it *** model was able to reproduce the occurrence of low adhesion region seen in experimental results with different particle concentrations.

关键词： coefficient of adhesion tribology transient effects wheel-rail contact

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Prediction of ball-on-plate friction and wear by ANN with data-driven optimization

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Friction 2024年第6期12卷 1235-1249页

作者： alexander KOVALEV Yu TIAN Yonggang MENG State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing 100084China

For training artificial neural network(ANN),big data either generated by machine or measured from experiments are used as input to"learn"the unspecified functions defining the *** experimental data are fed directly into the optimizer allowing training to be performed according to a predefined loss *** predict sliding friction and wear at mixed lubrication conditions,in this study a specific ANN structure was so designed that deep learning algorithms and data-driven optimization models can be *** ball-on-plate friction and wear data were analyzed using the specific training procedure to optimize the weights and biases incorporated into the neural layers of the ANN,and only two independent experimental data sets were used during the ANN optimization *** the training procedure,the ANN is capable to predict the contact and hydrodynamic pressure by adapting the output data according to the tribological condition implemented in the optimization algorithm.

关键词： machine learning deep learning artificial neural network mixed lubrication

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Unveiling the atomic-scale transition between light harvesting and photoprotective states in plant photosynthesis

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Science China Chemistry 2024年第5期67卷 1375-1377页

作者： alexander V.Ruban School of Biological and Behavioural Sciences Queen Mary University of LondonLondon E14NSUK

Non-photochemical chlorophyll fluorescence quenching(NPQ) stands as a cornerstone in the realm of photosynthesis research, attracting generations of dedicated scientists in their quest to unravel its mysteries. This mechanism, crucial for safeguarding photosynthesis, plays a pivotal role in regulating light harvesting, particularly in oxygenic photosynthesis where the oxygen-evolving photosystem II (PSII)is susceptible to photodamage [1].

关键词： harvesting protective attracting

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Competitive Resource Allocation Among Urban Congestion Areas in a Modern Big City

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Journal of the Operations Research Society of China 2024年第1期12卷 133-153页

作者： alexander Krylatov Anastasiya Raevskaya Institute of Applied Mathematical Research of the Karelian Research Centre of the Russian Academy of Sciences Petrozavodsk185910Russia Saint Petersburg State University Saint Petersburg199034Russia

The continuing growth of modern big cities leads to their spatial expansion and the emergence of new road connections and urban *** where large transportation flows of pedestrians,passengers,and drivers come together create demand points,which attract business companies that strive to allocate their resources in the most sought-after ***,the law of supply and demand restrains companies from allocating all their resources solely in the most popular congestion areas since the more valuable an urban area,the higher the cost to be paid for a resource unit allocation *** a result,companies act in a non-cooperative manner and try to minimize their own overall costs when allocating resources across available commercial areas in a big ***-cooperative behavior of companies leads to the problem of Nash equilibrium search in the game of competing *** this paper,we study the corresponding resource allocation game under affine cost functions and obtain Nash equilibrium strategies in explicit *** findings allow us to develop a simple procedure for computing Nash equilibria in the game of companies allocating their resources among urban congestion *** computational study demonstrates the dependence of the average price for resource allocation on the number of players and their resource *** outcome of the paper contributes to flow theory and seems to be fresh and useful for managers.

关键词： Resource allocation Nash equilibrium Affine costs

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A Converse Theorem for Split SO_(2l) over Finite Fields

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Acta Mathematica Sinica,English Series 2024年第3期40卷 731-771页

作者： alexander HAZELTINE Bai Ying LIU Department of Mathematics Purdue University150 N.University St.West LafayetteIN 47907USA E-mail:ahazelti@purdue.edu liu2053@purdue.edu

we prove a converse theorem for split even special orthogonal groups over finite *** is the only case left on converse theorems of classical groups and the difficulty is the existence of the outer automorphism. In thi... 详细信息

关键词： Converse theorems generic cuspidal representations even special orthogonal groups

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Architecture of Graphics System with 3D Acceleration Support for Embedded Operating Systems

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Tsinghua Science and Technology 2024年第3期29卷 863-873页

作者： alexander Giatsintov Kirill Mamrosenko Pavel Bazhenov Center of Visualization and Sattelite Information Technologies Scientific Research Institute for System Analysis of the Russian Academy of Sciences(SRISA RAS)Moscow 117218Russia

An increasing number of tasks now require the use of hardware accelerators to reduce the time required for computation and display the computational *** paper presents a new graphics system architecture for operating systems(OSs)with microkernel architecture,including real-time *** proposed system architecture provides capabilities for displaying graphical images on various information display devices and for accelerating graphical operations on *** architecture of the graphics system uses a concept of allocators to manage system and video memory,provides an abstraction of memory operations with a single interface for video memory management,and simplifies memory handling where incorrect operation is the cause of many failures.A comparison between the performance of a real-time OS and Linux OS implementing the graphics system using the example of a glmark2 benchmark is presented,thereby the superiority of the proposed architecture in several scenarios is demonstrated.

关键词： real-time operating system(RTOS) graphics system rendering system architecture operatingsystem visualization system programming

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Comment on “Ferroelectric composite-based piezoelectric energy harvester for self-powered detection of obstructive sleep”

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Journal of Materiomics 2024年第5期10卷 1144-1146页

作者： alexander Tkach Olena Okhay CICECO-Aveiro Institute of Materials Department of Materials and Ceramic EngineeringUniversity of Aveiro3810-193AveiroPortugal TEMA-Centre for Mechanical Technology and Automation Department of Mechanical EngineeringUniversity of Aveiro3810-193AveiroPortugal LASI-Intelligent Systems Associate Laboratory 4800-058GuimaraesPortugal

SrTi_(2)O_(5) particles were claimed by Panda et *** *** 2023;9:609 as a new lead-free ferroelectric material with orthorhombic symmetry and space group of Cmm2,being,therefore,employed as a base of piezoelectric energy ***,in this comment we express concerns regarding the presence of the piezoelectricity in the studied material and the interpretation of the structural,microstructural,and ferroelectric results in that publication as those associated with SrTi_(2)O_(5).we also note that the presented dielectric results are contradictory and that many important details are missing.

关键词： SrTiO_(3) Dielectric permittivity Ferroelectrics Piezoelectrics Energy harvesting

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Emergency department management of acute agitation in the reproductive age female and pregnancy

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world Journal of Emergency Medicine 2024年第2期15卷 83-90页

作者： Ariella Gartenberg Kayla Levine alexander Petrie Department of Emergency Medicine Jacobi Medical Center and Montefiore Medical CenterNY 10461USA Department of Psychiatry and Behavioral Sciences Albert Einstein College of Medicine and Montefiore Medical CenterNY 10461USA Department of Emergency Medicine Jacobi Medical Center and North Central Bronx HospitalNY 10461USA

BACKGROUND:Agitation is a common presentation within emergent departments(EDs).Agitation during pregnancy should be treated as an obstetric emergency,as the distress may jeopardize both the patient and *** safety of psychotropic medications in the reproductive age female has not been well *** review aimed to explore a summary of general agitation recommendations with an emphasis on ED management of agitation during ***:A literature review was conducted to explore the pathophysiology of acute agitation and devise a preferred treatment plan for ED management of acute agitation in the reproductive age or pregnant ***:while nonpharmacological management is preferred,ED visits for agitation often require medical *** should be selected based on the etiology of agitation and the clinical setting to avoid major adverse *** effects are common in pregnant *** mild to moderate agitation in pregnancy,diphenhydramine is an effective sedating agent with minimal adverse *** moderate to severe agitation,high-potency typical psychotropics are preferred due to their neutral effects on *** has become the most frequently utilized psychotropic for agitation during *** generation psychotropics are often utilized as second-line therapy,including *** and ketamine have demonstrated adverse fetal ***:while randomized control studies cannot be ethically conducted on pregnant patients requiring sedation,animal models and epidemiologic studies have demonstrated the effects of psychotropic medication exposure in *** the fetal risk associated with multiple doses of psychotropic medications remains unknown,weighing the risks and benefits of each agent,while utilizing the lowest effective dose remains critical in the treatment of acute agitation within the EDs.

关键词： Agitation Pregnancy Haloperidol Ketamine Benzodiazepines

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