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Validation and reproducibility of the Heidelberg Edge Perimeter in the detection of glaucomatous visual field defects

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 577-581页

作者： Qi N.Cui Priyanka Gogt Jonathan M.Lam Safa Siraj lisa a.hark Jonathan S.Myers L.Jay Katz Michael Waisbourd Glaucoma Research Center Wills Eye Hospital Scheie Eye Center University of Pennsylvania Department of Ophthalmology Tel Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel Aviv University

AIM: To validate the ability of the Heidelberg Edge Perimeter(HEP) in detecting glaucomatous visual field(VF) defects compared to the Octopus Visual Field(OVF) Analyzer and to determine the test-retest repeatability of both ***: This prospective, cross-sectional study was conducted at Wills Eye Hospital, Philadelphia, PA. Glaucoma subjects and unaffected controls underwent VF testing using HEP standard automated perimetry(SAP) Ⅲ 30-2 Adaptive Staircase Thresholding Algorithm(ASTA) FAST protocol and OVF G-TOP white-on-white strategy. Testing order was randomized. Pearson's correlation coefficient was calculated for both mean deviation(MD) and pattern standard deviation/square root of loss of variance(PSD/s LV). Receiver operating characteristic(ROC) curves were used to determine the diagnostic abilities of both modalities. Glaucoma subjects returned for repeat testing and intraclass correlation coefficients(ICCs) were calculated to assess test-retest repeatability. RESULTS: Seventy-nine subjects with glaucoma and 36 unaffected controls were enrolled. HEP and OVF were significantly correlated for both MD(r=-0.84; P<0.01) and PSD/s LV(r=0.79; P<0.01). Areas under the ROC curves(AUCs) were also comparable between HEP and OVF for both MD(0.74 and 0.79, respectively; P=0.26) and PSD/sL V(0.74 and 0.82; P=0.08). ICC was high for both HEP (0.96 for MD, 0.95 for PSD/s LV) and OVF(0.82 and 0.88, respectively). Mean test duration(min) was significantly shorter for OVF(2.63) compared to HEP(5.15; P<0.01). CONCLUSION: HEP and OVF show strong correlation for both MD and PSD/s LV, and have similar validity for detecting glaucoma. The test-retest repeatability is high for both HEP and OVF, however the average testing duration of HEP is significantly longer than that of OVF.

关键词： glaucoma Heidelberg Edge Perimeter standard automated perimetry Octopus Visual Field Analyzer visual field

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Perspective on early lens extraction for primary angle-closure glaucoma

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Eye Science 2017年第1期32卷 9-11页

作者： Osama M.Ahmed lisa a.hark Michael Waisbourd Glaucoma Research Center Wills Eye HospitalPhiladelphiaPAUSA Department of Ophthalmology Tel-Aviv Medical CenterAffiliated to the Sackler Faculty of MedicineTel-Aviv UniversityTel-AvivIsrael

Primary angle-closure glaucoma(PACG)is a subtype of glaucoma that affects 16 million people worldwide,of whom4 million are bilaterally *** prevalence of PACG is expected to increase to 21 million cases by 2020,and it ... 详细信息

关键词： PACG IOP Perspective on early lens extraction for primary angle-closure glaucoma LPI

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Stability Problem for Jensen-type Functional Equations of Cubic Mappings

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Acta Mathematica Sinica,English Series 2006年第6期22卷 1781-1788页

作者： Kil-WoungJUN hark-MahnKIM Department of Mathematics Chungnam National University

In this paper, we establish the general solution and the generalized Hyers-Ulam-Rassias stability problem for a cubic Jensen-type functional equation,4f（（3x＋y）/4）＋4f（（x＋3y）/4）=6f（（x＋y）/2）＋f（x）＋f（y）,9f（（2x＋y/3）＋9f（（x＋2y）/3）=16f（（x＋y）/2＋f（x）＋f（y）in the spirit of D. H. Hyers, S. M. Ulam, Th. M. Rassias and P. Gaevruta.

关键词： Jensen equation Hyers-Ulam-Rassias stability cubic mapping

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Refined Functional Equations Stemming from Cubic,Quadratic and Additive Mappings

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Acta Mathematica Sinica,English Series 2009年第10期25卷 1595-1608页

作者： Ick-Soon CHANG Eunyoung SON hark-Mahn KIM Department of Mathematics Mokwon University Department of Mathematics Chungnam National University

Let n ≥ 2 be an integer. In this paper, we investigate the generalized Hyers-Ulam stability problem for the following functional equation f（n-1∑j=1 xj＋2xn）＋f（n-1∑j=1 xj-2xn）＋8 n-1∑j=1f（xj）=2f（n-1∑j=1 xj... 详细信息

关键词： generalized Hyers-Ulam stability functional equations cubic mappings quadratic mappings difference operator

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Approximate （m, n）-Cauchy-Jensen Additive Mappings in C^＊-algebras

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Acta Mathematica Sinica,English Series 2011年第10期27卷 1907-1922页

作者： John Michael RASSIAS Kil Woung JUN hark-Mahn KIM Pedagogical Department E. E. Section of Mathematics and Informaties National and Capodistrian University of Athens 4 Agamemnonos St. Aghia Paraskevi Athens 15342 Greece Department of Mathematics Chungnam National University 220 Yuseong-Gu Daejeon 305-764 Korea

Concerning the stability problem of functional equations, we introduce a general （m, n）- Cauchy-Jensen functional equation and establish new theorems about the Hyers-Ulam stability of general （m, n）-Cauchy Jensen additive mappings in C^＊-algebras, which generalize the result＇s obtained for Cauchy-Jensen type additive mappings.

关键词： Generalized Hyers Ulam stability (m n)-Cauchy-Jensen mappings unitary group C^*- algebra isomorphisms derivations

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miR-215 overexpression distinguishes ampullary carcinomas from pancreatic carcinomas

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Hepatobiliary & Pancreatic Diseases International 2015年第3期14卷 325-329页

作者： Dong Ho Choi Sang Jae Park hark Kyun Kim Department of Surgery Hanyang University School of Medicine Center for Liver Cancer National Cancer Center Biomolecular Function Research Branch National Cancer Center

Distinguishing ampullary carcinoma from pancreatic carcinoma is important because of their different prognoses. microRNAs are differentially expressed according to the tissue of origin. However, there is rare research on the differential diagnosis between the two types of cancers by microRNA in periampullary cancers. The present study was undertaken to compare microRNA profiles between ampullary and pan- creatic carcinomas using microarrays, miR-215 was most significantly overexpressed in ampullary carcinomas; whereas the expressions of miR-134 and miR-214 were significantly lower in ampuUary carcinomas than in pancreatic carcino- mas. When these discriminatory microRNAs were applied to liver metastases, they were correctly predicted for the tissue of origin. Although this study is limited by small sample size, striking difference in microRNA expression and concordant expression of discriminating microRNAs in primary tumors and metastases suggest that these novel discriminatory mi- croRNAs warrant future validation.

关键词： ampulla of Vater pancreatic cancer gene expression

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Mirror-twin induced bicrystalline InAs nanoleaves

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Nano Research 2016年第3期9卷 766-773页

作者： Mun Teng Soo Kun Zheng Qiang Gao hark Hoe Tan Chennupati Jagadish Jin Zou Materials Engineering The University of Queensland St. Lucia QLD 4072 Australia Centre for Microscopy and Microanalysis The University of Queensland St. Lucia QLD 4072 Australia Australian Institute for Bioengineering and Nanotechnology The University of Queensland St. Lucia QLD 4072 Australia Department of Electronic Materials Engineering Research School of Physics and Engineering The Australian National University Canberra ACT2601 Australia

In this study, leaf-like one-dimensional InAs nanostructures were grown by the metal-organic chemical vapor deposition method. Detailed structural charac- terization suggests that the nanoleaves contain relatively low-energy {122} or {133} mirror twins acting as their midribs and narrow sections connecting the nanoleaves and their underlying bases as petioles. Importantly, the mirror twins lead to identical lateral growth of the twinned structures in terms of crystallography and polarity, which is essential for the formation of lateral symmetrical nanoleaves. It has been found that the formation of nanoleaves is driven by catalyst energy minimization. This study provides a biomimic of leaf found in nature by fabricating a semiconductor nanoleaf.

关键词： InAs nanoleaf twin boundary mirror twin

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Ultrasensitive Indium Phosphide Nanomembrane Wearable Gas Sensors

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Energy & Environmental Materials 2024年第6期7卷 209-217页

作者： Shiyu Wei Tuomas Haggren Zhe Li hark Hoe Tan Chennupati Jagadish Antonio Tricoli Lan Fu Department of Electronic Materials Engineering Australian Research Council Centre of Excellence for Transformative Meta-Optical SystemsResearch School of PhysicsThe Australian National UniversityCanberraACT 2600Australia Nanotechnology Research Laboratory Research School of ChemistryCollege of ScienceThe Australian National UniversityCanberraACT 2600Australia Nanotechnology Research Laboratory Faculty of EngineeringThe University of SydneyCamperdownNSW 2006Australia

Air quality is deteriorating due to continuing urbanization and *** particular,nitrogen dioxide(NO_(2))is a biologically and environmentally hazardous byproduct from fuel combustion that is ubiquitous in urban *** address this issue,we report a high-performance flexible indium phosphide nanomembrane NO_(2)sensor for real-time air quality *** ultralow limit of detection of~200 ppt and a fast response have been achieved with this device by optimizing the film thickness and doping concentration during indium phosphide *** varying the film thickness,a dynamic range of values for NO_(2)detection from parts per trillion(ppt)to parts per million(ppm)level have also been demonstrated under low bias voltage and at room temperature without additional light *** measurements show an adequately stable response after repeated ***-site testing of the sensor in a residential kitchen shows that NO_(2)concentration from the gas stove emission could exceed the NO_(2)Time Weighted Average limit,i.e.,200 ppb,highlighting the significance of real-time ***,the indium phosphide nanomembrane sensor element cost is estimated at<0.1 US$due to the miniatured size,nanoscale thickness,and ease of *** these superior performance characteristics,low cost,and real-world applicability,our indium phosphide nanomembrane sensors offer a promising solution for a variety of air quality monitoring applications.

关键词： air quality monitoring flexible III-V semiconductors nanofilm ultrathin

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Nonpolar Al_(x)Ga_(1−x)N/Al_(y)Ga_(1−y)N multiple quantum wells on GaN nanowire for UV emission

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Nano Research 2022年第8期15卷 7670-7680页

作者： Sonachand Adhikari Olivier Lee Cheong Lem Felipe Kremer Kaushal Vora Frank Brink Mykhaylo Lysevych hark Hoe Tan Chennupati Jagadish Department of Electronic Materials Engineering Research School of PhysicsThe Australian National UniversityCanberraAustralian Capital Territory 2601Australia Semiconductor Device Fabrication Group CSIR-Central Electronics Engineering Research InstitutePilaniRajasthan 333031India Australian National Fabrication Facility ACT Node Research School of PhysicsThe Australian National UniversityCanberraAustralian Capital Territory 2601Australia Centre for Advanced Microscopy The Australian National UniversityCanberraAustralian Capital Territory 2601Australia Australian Research Council Centre of Excellence for Transformative Meta-Optical Systems Research School of PhysicsThe Australian National UniversityCanberraAustralian Capital Territory 2601Australia

Nonpolar m-plane AlGaN offers the advantage of polarization-free multiple quantum wells(MQWs)for ultraviolet(UV)emission and can be achieved on the sidewalls of selective area grown GaN *** reveal that the growth of AlGaN on GaN nanowires by metal organic chemical vapor deposition(MOCVD)is driven by vapor-phase diffusion,and consequently puts a limit on the pitch of nanowire array due to shadowing *** insight into the difficulty of achieving metal-polar AlGaN nanowire by selective area growth(SAG)in MOCVD is also provided and can be attributed to the strong tendency to form pyramidal structure due to a very small growth rate of{1011}semipolar planes compared to(0001)*** nonpolar m-plane sidewalls of GaN nanowires obtained via SAG provides an excellent platform for growth of nonpolar AlGaN *** emission from mplane Al_(x)Ga_(1−x)N/Al_(y)Ga_(1−y)N MQWs grown on sidewalls of dislocation-free GaN nanowire is demonstrated in the wavelength range of 318–343 nm.

关键词： metal organic chemical vapor deposition(MOCVD) nanowire nonpolar plane AlGaN selective area growth multiple quantum wells

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Electrically programmable solid-state metasurfaces via flash localised heating

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Light(Science & Applications) 2023年第3期12卷 391-397页

作者： Khosro Zangeneh Kamali Lei Xu Nikita Gagrani hark Hoe Tan Chennupati Jagadish Andrey Miroshnichenko Dragomir Neshev Mohsen Rahmani ARC Centre of Excellence for Transformative Meta-Optical Systems(TMOS) Research School of PhysicsThe Australian National UniversityCanberraACT 2601Australia Advanced Optics and Photonics Laboratory Department of EngineeringSchool of Science and TechnologyNottingham Trent UniversityNottinghamNG118NSUK School of Engineering and Information Technology University of New South WalesCanberraACT 2600Australia

In the last decades,metasurfaces have attracted much attention because of their extraordinary light-scattering ***,their inherently static geometry is an obstacle to many applications where dynamic tunability in their optical behaviour is ***,there is a quest to enable dynamic tuning of metasurface properties,particularly with fast tuning rate,large modulation by small electrical signals,solid state and programmable across multiple ***,we demonstrate electrically tunable metasurfaces driven by thermo-optic effect and flash-heating in *** show a 9-fold change in transmission by<5 V biasing voltage and the modulation rise-time of<625µ*** device consists of a silicon hole array metasurface encapsulated by transparent conducting oxide as a localised *** allows for video frame rate optical switching over multiple pixels that can be electrically *** of the advantages of the proposed tuning method compared with other methods are the possibility to apply it for modulation in the visible and near-infrared region,large modulation depth,working at transmission regime,exhibiting low optical loss,low input voltage requirement,and operating with higher than video-rate switching *** device is furthermore compatible with modern electronic display technologies and could be ideal for personal electronic devices such as flat displays,virtual reality holography and light detection and ranging,where fast,solid-state and transparent optical switches are required.

关键词： tuning flash state

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