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Diagnostic Value of Endoscopic Ultrasound in Staging Rectal Cancer

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Proceedings of Anticancer Research 2024年第4期8卷 48-53页

作者： linxia liu Ke Chen Nantong Tumor Hospital Nantong 226300Jiangsu ProvinceChina Department of Endoscopy Cancer Hospital Affiliated to Fudan UniversityShanghai 200000China

Objective:To explore the diagnostic value of endoscopic ultrasound(EUS)in the staging of rectal ***:Fifty patients with rectal cancer,treated at the Department of Endoscopy,Cancer Hospital Affiliated to Fudan University,from March 2023 to June 2024,were *** patients underwent EUS and computed tomography(CT)examination within two weeks before *** postoperative pathological staging was used as the standard to compare the accuracy of tumor TN staging using EUS and/or ***:The accuracy rates of T and N staging by abdominal spiral CT were 72.00%and 76.00%,respectively,while those by EUS were 88.00%and 74%,*** was a significant difference in the accuracy of T staging between the two methods(both P<0.05).Conclusion:EUS has high diagnostic value in the staging of rectal cancer,providing important reference information for clinicians,aiding in the development of personalized treatment plans,and assessing patient prognosis.

关键词： Endoscopic ultrasound Rectal cancer Diagnostic value

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介入治疗脾动脉瘤

中国介入影像与治疗学 2024年第9期21卷 569-571页

作者：周升毅杨庆刘林霞王永祥陈淑章曾宇四川护理职业学院附属医院(四川省第三人民医院)放射科四川成都610100 隆昌市人民医院放射科四川内江642160

脾动脉瘤(splenic artery aneurysm,SAA)发病率较低,且起病隐匿,未破裂时多无明显临床症状,部分可因外伤、妊娠或门静脉高压而破裂并出现严重后果[1]。随着健康意识的提高及影像学检查的日益普及,近年越来越多的未破裂SAA得以检出。本... 详细信息

脾动脉瘤(splenic artery aneurysm,SAA)发病率较低,且起病隐匿,未破裂时多无明显临床症状,部分可因外伤、妊娠或门静脉高压而破裂并出现严重后果[1]。随着健康意识的提高及影像学检查的日益普及,近年越来越多的未破裂SAA得以检出。本文报道介入治疗9例脾动脉瘤效果。

关键词：脾动脉瘤栓塞,治疗性支架

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A cyclin protein governs the infectious and sexual life cycles of Cryptococcus neoformans

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Science China(Life Sciences) 2021年第8期64卷 1336-1345页

作者： Pengjie Hu linxia liu Weixin Ke Xiuyun Tian Linqi Wang State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Cell cycle is a fundamental process underlying growth and development in evolutionarily diverse organisms, including fungi. In human fungal pathogens, cell cycle control generally determines their life cycles, either in the environment or during ***, cell cycle components can potentially serve as important targets for the development of antifungal strategy against fungal infections. Here, in Cryptococcus neoformans, the most common cause of fatal fungal meningitis, we show that a previously uncharacterized B-type cyclin named Cbc1 is essential for both its infectious and sexual cycles. We reveal that Cbc1 coordinates various sexual differentiation and molecular processes, including meiosis. Especially, the absence of Cbc1 abolishes formation of sexual spores in C. neoformans, which are presumed infectious particles. Cbc1 is also required for the major Cryptococcus pathogenic attributes. Virulence assessment using the murine model of cryptococcosis revealed that the cbc1 mutant is ***, our results provide an important insight into how C. neoformans employs shared cell cycle regulation to coordinate its infectious and sexual cycles, which are considered crucial for virulence evolution and the production of infectious spores.

关键词： life cycles Together

On the measurement for the speed of gravity

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Chinese Science Bulletin 2014年第4期59卷 828-832页

作者： linxia liu Chenggang Shao Department of Electronics and Communication Engineering Henan Mechanical and Electrical Engineering College School of Physics Huazhong University of Science and Technology

Newton’s law of gravity is a theory of instantaneous action at a ***,Einstein’s general relativity states that the speed of gravity equals the speed of light,which is ***,it is a worthy problem to discuss if Newton’s law of gravity needs modification,when studying and observing the gravitational *** this paper,it is shown that the Newton’s law of gravity is fully applicable in the framework of general *** on the post-Newtonian approximation,we find that the observable effect for the speed of gravity is irrelevant to the velocity of a moving source,but it is dependent on its *** general,the effect of the speed of gravity is so weak that today’s any astronomical observations,including the sun tidal observations,can not confirm that the gravitational field travels at the speed of light.

关键词：重力定律速度广义相对论牛顿定律测量引力场爱因斯坦重力潮汐

Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

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Synthetic and Systems Biotechnology 2020年第3期5卷 200-205页

作者： Zhu Li Dongqin Ding Huiying Wang linxia liu Huan Fang Tao Chen Dawei Zhang Key Laboratory of Systems Bioengineering of the Ministry of Education School of Chemical Engineering and TechnologySynBio Research PlatformCollaborative Innovation Centre of Chemical Science and EngineeringTianjin UniversityTianjin300072China Key Laboratory of Systems Microbial Biotechnology Chinese Academy of SciencesTianjin300308China Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin300308China University of Chinese Academy of Sciences Beijing100049China

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target ***,the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherichia ***,glutamine synthesis was improved by expressing heterologous glutamine synthetase from Bacillus subtilis and Bacillus megaterium in the engineered Escherichia coli strain KW001,resulting in the best candidate strain *** icd and gdhA were overexpressed in TS-1,which led to the accumulation of 1.060 g/L ***,one more copy of prs was introduced on the chromosome to increase the flux of 5-phospho-α-D-ribose 1-diphosphate followed by the expression of mutated serA and thrA to increase the precursor supply of serine,resulting in the accumulation of 1.380 g/L ***,to maintain cofactor balance,sthA and pntAB,encoding transhydrogenase,were *** sufficient amounts of precursors and balanced cofactors,the engineered strain could produce 1.710 g/L tryptophan after 48 h of shake-flask fermentation,which was 2.76-times higher than the titer of the parent *** together,our results demonstrate that the combination of optimizing precursor supply and regulating cofactor metabolism is an effective approach for high-level production of *** strategies could be applied to the production of other amino acids or related derivatives.

关键词： Escherichia coli Tryptophan Metabolic precursors Cofactor supply

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平面偏振光微小偏转角的精密测量

华中科技大学学报（自然科学版） 2007年第2期35卷 122-124页

作者：范淑华徐丽珊刘琳霞华中科技大学物理系湖北武汉430074

对一般的光路进行调制来测量微小偏转角的方法进行了改进.利用双重调制的方法,对平面偏振光的微小偏转角进行了精密的测量.这种方法利用两个磁光调制器分别对光路和信号本身进行调制,既有效增强了测量信号,又可消除由起偏器和检偏器引... 详细信息

对一般的光路进行调制来测量微小偏转角的方法进行了改进.利用双重调制的方法,对平面偏振光的微小偏转角进行了精密的测量.这种方法利用两个磁光调制器分别对光路和信号本身进行调制,既有效增强了测量信号,又可消除由起偏器和检偏器引起的角度误差,抑制背景光对实验的影响.本实验系统的分辨率已达到2.73×10-8rad.分析了存在的主要噪声,给出了提高整个实验系统的分辨率可能采取的措施.

关键词：消光比法拉第效应维尔德常数磁光玻璃

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市场经济下的电力负荷控制系统

华北电力技术 1999年第11期 59-60页

作者：吕林霞大同供电公司大同037008

在缺电形势下应运而生的电力负荷控制系统，已失去其原有作用，在市场经济形势下必须调整和拓展其功能，转换其服务对象，才能更好地发挥其作用，为此从６

关键词：负荷预测负荷控制电力系统市场经济供电企业

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用自旋极化扭秤探测自旋与质量相互作用

华中科技大学学报（自然科学版） 2006年第3期34卷 107-110页

作者：范淑华董瑶刘琳霞邵成刚华中科技大学物理系湖北武汉430074

利用扭秤探测自旋极化物体Sm2Co17与太阳质量之间的类似轴子的相互作用,充磁以后Sm2Co17的等效自旋电子数约为1.5×1023.初步实验结果表明,当相互作用程λ→∞时,自旋质量耦合常数的上限gsgp/(hc)<1.4×10-31.同时给出了对应的洛伦兹与... 详细信息

利用扭秤探测自旋极化物体Sm2Co17与太阳质量之间的类似轴子的相互作用,充磁以后Sm2Co17的等效自旋电子数约为1.5×1023.初步实验结果表明,当相互作用程λ→∞时,自旋质量耦合常数的上限gsgp/(hc)<1.4×10-31.同时给出了对应的洛伦兹与CPT破缺因子的上限在10-17eV水平.为了减小周围环境磁场对实验的影响,设计了三维Helmholtz线圈来补偿背景磁场.并从四个方面讨论了提高实验精度的方法.

关键词：自旋-质量相互作用耦合常数自旋极化扭秤洛仑兹与CPT对称破缺因子

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水下FG圆柱壳临界载荷和固有频率预测方法

郑州大学学报（工学版） 2021年第1期42卷 70-76页

作者：李戎杨萌刘林霞梁斌河南科技大学土木工程学院河南洛阳471023

针对水下功能梯度(FG)圆柱壳振动预测方法的不足,提出了一种适用于水下FG圆柱壳的屈曲临界载荷和固有频率预测方法。采用Flügge理论和波动法建立静水压力下FG圆柱壳耦合振动特征方程,使用牛顿迭代法求出静水压力下FG圆柱壳的固有频率,... 详细信息

针对水下功能梯度(FG)圆柱壳振动预测方法的不足,提出了一种适用于水下FG圆柱壳的屈曲临界载荷和固有频率预测方法。采用Flügge理论和波动法建立静水压力下FG圆柱壳耦合振动特征方程,使用牛顿迭代法求出静水压力下FG圆柱壳的固有频率,进而得到FG圆柱壳固有频率的平方和静水压力呈线性关系这一重要结论。基于此结论,通过使用线性拟合方法,最少需3组固有频率数据即可在保证精确度的基础上快速建立静水压力下FG圆柱壳固有频率的趋势线方程,从而得到屈曲临界载荷预测值以及任意静水压力下固有频率预测值。通过多组算例对比分析,结果表明:该方法预测结果与实际结果几乎一致,预测精度高,计算量小,便于实际应用。

关键词：水下功能梯度圆柱壳屈曲临界载荷固有频率静水压力预测方法