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Time Course of Postoperative Complications in Low-Risk Women after Planned Cesarean Section

Open Journal of Obstetrics and Gynecology 2022年第5期12卷 394-407页

作者： Anne Raabjerg Kruse linn håkonsen arendt Christian Erikstrup Ulrik Schiøler Kesmodel Finn Friis Lauszus Niels Uldbjerg Iben Sundtoft Axel Forman Department of Obstetrics and Gynecology Regional Hospital G&oslash dstrup Herning Denmark Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark Department of Clinical Immunology Aarhus University Hospital Aarhus Denmark Department of Obstetrics and Gynecology Aalborg University Hospital Aalborg Denmark

Objectives: Length of hospital stay after cesarean section is today much shorter than previously, and a stay of only 1 day is used in many departments. however, complications requiring immediate treatment must be diagnosed before leaving hospital. We assessed the time interval from planned cesarean section to diagnosis of major complications in low-risk women to estimate a safe time of discharge. Methods: We performed a retrospective observational study among 5633 women undergoing planned cesarean section from 2001-2017 at Aarhus University hospital, Denmark. The inclusion criterion was postoperative complication graded as Clavien-Dindo ≥ II. Exclusion criteria were preoperative comorbidity or problems during surgery indicative of need for prolonged stay. Time from cesarean section to suspicion of a postoperative complication was the primary endpoint. Results: The study population consisted of 116 women with unexpected postoperative complications, 47 classified as Clavien-Dindo II and 69 as Clavien-Dindo III-IV. In 63 of the 116, the diagnoses were suspected within 24 hours (Clavien-Dindo II: 25, Clavien-Dindo III-IV: 38). These included all cases of relaparotomy and uterine atony with immediate need of medical treatment. Acute colonic pseudo-obstruction was diagnosed within 2 days, while other complications were suspected and treated 2 to 10 days postoperatively. Conclusions: Among low-risk women with a postoperative complication, all cases requiring relaparotomy and medically treated uterine atony were suspected within 24 hours after surgery. Discharge 24 hours after planned cesarean section seems safe in low-risk patients.

关键词： Cesarean Section Postoperative Complications Postoperative hemorrhage Early Discharge Length of hospital Stay

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s age at puberty associated with semen quality ant ＇eproductive hormones in young adult life？

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Asian Journal of Andrology 2017年第6期19卷 625-632页

作者： Lea LB Lauridsen linn h arendt henrik Stovring Jorn Olsen Cecilia h Ramlau-hansen 1Department of Public health Section for Epidemiology Aarhus University 8000 Aarhus C Denmark Department of Public health Section for 8iostatistics Aarhus University 8000 Aarhus C Denmark Department of Clinical Epidemiology Aarhus University Hospital 8200 Aarhus N Denmark

The evidence is scarce on the association between age at puberty and semen quality. A cohort of 320 Danish men aged 18-21 years enrolled in the ＂healthy habits for Two＂ birth cohort provided self-reported data on pubertal indicators and delivered semen and blood samples. The results indicated an association between older age at pubertal development and lower semen quality and altered reproductive hormones concentrations as measured in young adult life. Men who had their first nocturnal emission, start of pubic hair growth and first voice break episode when older than 15 years had 37.0%, 45.0% and 32.7% lower sperm concentration; 37.8%, 44.2% and 29.1% lower total sperm count; 7.4%, 13.4% and 15.3% lower testosterone concentration; and 21.3%, 1.5% and 3.7% lower inhibin B concentration, respectively, compared with the men who were younger than 13 years at their first pubertal indicators. Only few of the results were statistically significant, but similar tendencies were seen in several of the reproductive parameters suggesting an association between the timing of pubertal development and reproductive health later in life.

关键词： pubertal development puberty reproductive health reproductive hormones semen quality

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Timing of pubertal development in boys born with cryptorchidism and hypospadias:a nation wide cohort study

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Asian Journal of Andrology 2019年第6期21卷 551-556页

作者： linn hakonsen arendt Andreas Ernst Lea Lykke Braskhoj Lauridsen Nis Brix Jorn Olsen Cecilia host Ramlau-hansen Department of Public health Section for EpidemiologyAarhus UniversityAarhus 8000Denmark Perinatal Epidemiology Research Unit Department of Paediatric and Adolesce nt Medici neAarhus Un iversity HospitalAarhus 8000Den mark Department of Clin ical Epidemiology Aarhus University HospitalAarhus 8000Denmark.

Pubertal development may be altered in boys with cryptorchidism and hypospadias,but existing kno wledge is inc on siste ***,we investigated the association between cryptorchidism and hypospadias and pubertal development in a large cohort *** in the Puberty Cohort,a cohort nested within the Danish National Birth Cohort,were in eluded in this *** on cryptorchidism and hypospadias was retrieved from the Danish National Patient *** 11 years until 18 years or full pubertal developme nt,info rmatio n on physical markers of pubertal developme nt was provided biannu ally,in eluding Tanner stages,axillary hair,acne,voice break,and first *** multivariate regression models for interval censored data,the mean(95%confidence intervals[Cis])d iff ere nces in months in obtaining the pubertal markers between boys with and without the anomalies were *** 7698 boys,196(2.5%)had cryptorchidism and 60(0.8%)had *** with hypospadias experienced first ejaculation and voice break 7.7(95%Cl:2.5-13.0)months and 4.5(95%Cl:0.3-8.7)months later than boys without hypospadias?The age at attaining the Tanner stages for gonadal and pubic hair growth was also higher,though not statistically *** development seemed unaffected in boys with mild as well as severe cryptorchidism?In conclusion,hypospadias may be associated with delayed pubertal development,but pubertal development seems unaffected by *** relation between hypospadias and later pubertal development may be due to the underlying shared in utero risk or genetic factors.

关键词： congenital abnormalities cryptorchidism hypospadias prenatal exposure delayed effects puberty Tanner stages

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