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The mitochondria-localized protein OsNDB2 negatively regulates grain size and weight in rice

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The Crop Journal 2022年第6期10卷 1819-1824页

作者： Mingxin Guo Jiajia Liu linlin hou Suna Zhao Nana Zhang Lili Lu Xusheng Zhao College of Life Sciences Luoyang Normal UniversityLuoyang 471934HenanChina

Grain size is a determinant of rice grain *** plants,mitochondria supply energy for cellular metabolism via the mitochondrial electron transport *** we report that OsNDB2,which encodes a putative rotenone-insensitive typeⅡNAD(P)H dehydrogenase(ND),negatively regulates grain size and weight in *** ND members representing three major types of rice were identified,and the predicted OsNDB2 protein was localized to *** of OsNDB2 transcripts were higher in young panicles and leaf ***2 overexpression reduced grain length,grain width,and 1000-grain weight and moderately influenced plant height,while knockout of OsNDB2 increased grain size and 1000-grain *** mutations of OsNDB2 were associated with diverse grain *** observations revealed that variations in grain size of transgenic lines were caused by change in cell expansion but not cell proliferation in spikelet *** study sheds light on OsNDB2 function and provides a new potential breeding approach for increasing rice grain size and weight.

关键词： Rice OsNDB2 TypeⅡNAD(P)H dehydrogenase Allelic mutants Grain size

Finite-time stability of switched linear systems 36

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Finite-time stability of switched linear systems

Event-triggered finite-time guaranteed cost control of asynchronous switched systems under the round-robin protocol via an AED-ADT method

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作者： linlin hou Chuanguang Sun Hangli Ren Yunliang Wei School of Control Science and Engineering Dalian University of Technology School of Information Science and Engineering Qufu Normal University Basic Teaching Department ShanDong Water Conservancy Vocational College School of Engineering Qufu Normal University School of Mathematical Sciences Qufu Normal University

ISBN: (纸本)9781538629185

In this paper, the problem of finite-time stability is studied for a class of switched linear systems, where some subsystems are not finite-time stable. A novel average dwell time approach for finite-time stability of switched linear systems in which not all subsystems are finite-time stable is first proposed. Moreover, by constructing a new multiple Lyapunov functional, sufficient condition is provided to cope with the problem of finite-time stability for the given systems. Finally, a numerical example is illustrated to show the effectiveness of the proposed results.

关键词： Switched linear systems average dwell time finite-time stability

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Frontiers of Information Technology & Electronic Engineering 2024年第10期25卷 1378-1389页

作者： Hangli REN Qingxi FAN linlin hou School of Electric Information Engineering Zhengzhou University of Light IndustryZhengzhou 450000China School of Information Science and Engineering Qufu Normal UniversityRizhao 276826China

This paper focuses on addressing the problems of finite-time boundedness and guaranteed cost control in switched systems under asynchronous *** reduce redundant information transmission and alleviate data congestion of sensor nodes,two schemes are proposed:the event-triggered scheme(ETS)and the round-robin protocol(RRP).These schemes are designed to ensure that the system exhibits good dynamic characteristics while reducing communication *** the field of finite-time control,a switching signal is designed using the admissible edge-dependent average dwell time(AED-ADT)*** method involves a slow AED-ADT switching and a fast AED-ADT switching,which are respectively suitable for finite-time stable and finite-time unstable situations of the controlled system within the asynchronous switching *** constructing a double-mode dependent Lyapunov function,the finite-time bounded criterion and the controller gain of the switched systems are ***,the validity of the proposed results is showcased by implementing a buck-boost voltage circuit model.

关键词： Switched systems Event-triggered scheme Round-robin protocol Asynchronous switching Admissible edge-dependent average dwell time(AED-ADT) Guaranteed cost control

Stabilization of switched linear systems under asynchronous switching subject to admissible edge-dependent average dwell time

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Frontiers of Information Technology & Electronic Engineering 2022年第5期23卷 810-822页

作者： linlin hou Xuan MA Haibin SUN School of Computer Science Qufu Normal UniversityRizhao 276826China College of Engineering Qufu Normal UniversityRizhao 276826China

The problem of stabilizing switched linear systems under asynchronous switching is *** admissible edge-dependent average dwell time method is applied to design a switching signal that comprises slow admissible edge-dependent average dwell time and fast admissible edge-dependent average dwell *** this switching signal,the restriction that the maximum delay of asynchronous switching is known in advance is *** constructed Lyapunov function is associated with both the system mode and controller *** stabilization criteria and the corresponding algorithm are presented to obtain the controller gains and to design the switching ***,two examples are given to demonstrate the effectiveness of the proposed results.

关键词： Asynchronous switching Admissible edge-dependent average dwell time Multi-Lyapunov function

A stable and efficient La-doped MIL-53(Al)/ZnO photocatalyst for sulfamethazine degradation

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Journal of Rare Earths 2022年第4期40卷 595-604,I0004页

作者： Qiuming Wei Wei Li Chun Jin Yasi Chen linlin hou Zhiliang Wu Zhongliang Pan Qinyu He Yinzhen Wang Dingyuan Tang Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials School of Physics and Telecommunication EngineeringSouth China Normal UniversityGuangzhou 510006China Guangdong Engineering Technology Research Center of Efficient Green Energy and Environmental Protection Materials Guangzhou 510006China School of Electrical and Electronic Engineering Nanyang Technological University639798Singapore

Photocatalytic technology can solve various environmental pollution problems,especially antibiotic pollution.A novel La-doped MIL-53(Al)/ZnO composite material was successfully synthesized by a combination of hydrothermal method and calcination,showing high photocatalytic degradation percent of sulfamethazine(SMT).The 2 mol%La MIL-53(Al)/ZnO photocatalyst shows the highest degradation efficiency toward SMT(92%)within 120 min,which is 4.1 times higher than pure ZnO(increased from 18%to 92%).In addition,the degradation analysis of SMT by high performance liquid chromatography proves that the products are CO_(2) and H_(2)*** improved photocatalytic activity is mostly caused by the following factors.(1)Doping La ions can decrease the band gap of ZnO,enhance light response,and effectively enhance the separation rate of photo-generated holes and electrons.(2)MIL-53(Al)can adsorb SMT and promote the separation of *** work shows that the synthesized La-doped MIL-53(Al)/ZnO photocatalyst is expected to be used as a green and effective method for treatment of environment water pollution.

关键词： Sulfamethazine Photocatalytic degradation Zinc oxide Lanthanum doping Rare earths

In situ immunomodulation of tumors with biosynthetic bacteria promote anti-tumor immunity

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Bioactive Materials 2024年第2期32卷 12-27页

作者： Zhongda Lin Fanqiang Meng Yumeng Ma Chi Zhang Zhirang Zhang Zhaoxin Yang Yuan Li linlin hou Yuzhong Xu Xin Liang Xudong Zhang Shenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases School of MedicineShenzhen Campus of Sun Yat-Sen UniversitySun Yat-Sen UniversityShenzhen518107GuangdongChina Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics Key Laboratory of Stem Cell and Regenerative Tissue EngineeringSchool of Basic Medical SciencesGuangdong Medical UniversityDongguan523808China Department of Clinical Laboratory Shenzhen Baoan HospitalThe Second Affiliated Hospital of Shenzhen UniversityShenzhen518101China

Immune checkpoint blockade(ICB)therapy potently revives T cell’s response to ***,patients suffered with tumors that had inadequate infiltrated immune cells only receive limited therapeutic benefits from ICB *** biology promotes the alternative strategy of harnessing tumor-targeting bacteria to synthesize therapeutics to modulate immunity in ***,we engineered attenuated Salmonella typhimurium VNP20009 with gene circuits to synthetize granulocyte-macrophage colony-stimulating factor(GM-CSF)and interleukin 7(IL-7)within tumors,which recruited dendritic cells(DCs)and enhanced T cell priming to elicit anti-tumor *** bacteria-produced GM-CSF stimulated the maturation of bone marrow-derived dendritic cells(BMDCs),while IL-7 promoted the proliferation of spleen isolated T cells and inhibited cytotoxicity T cell apoptosis in ***,engineered VNP20009 prefer to colonize in tumors,and inhibited tumor growth by enhancing DCs and T cell ***,the tumor-toxic GZMB^(+)CD8^(+)T cell and IFN-γ^(+)CD8^(+)T cell populations conspicuously increased with the treatment of engineered *** combination of GM-CSF-IL-7-VNP20009 with PD-1 antibody synergistically stunted the tumor progress and metastasis.

关键词： Salmonella GM-CSF IL-7 Synthetic biology Cancer immunotherapies

Filamentation initiated by Cas2 and its association with the acquisition process in cells

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International Journal of Oral Science 2019年第4期11卷 300-306页

作者： Lei Wang Xin Yu Mengjie Li Guiqin Sun Lin Zou Tiansheng Li linlin hou Yameng Guo Danfeng Shen Di Qu Xunjia Cheng Li Chen Department of Medical Microbiology Key Laboratory of Medical Molecular Virology of Ministries of Education and Health School of Basic Medical Sciences Fudan University 131 Dongan Road Shanghai China and College of Medical Technology Zhejiang Chinese Medical University

Cas1-and-Cas2-mediated new spacer acquisition is an essential process for bacterial adaptive *** process is critical for the ecology of the oral microflora and oral *** molecular mechanisms for spacer acquisition are known,it has never been established if this process is associated with the morphological changes of *** this study,we demonstrated a novel Cas2-induced filamentation phenotype in *** that was regulated by co-expression of the Cas1 protein.A 30 amino acid motif at the carboxyl terminus of Cas2 is necessary for this *** imaging analysis,we provided evidence to argue that Cas-induced filamentation is a step coupled with new spacer acquisition during which filaments are characterised by polyploidy with asymmetric cell *** work may open new opportunities to investigate the adaptive immune response and microbial balance for oral health.

关键词： function. process initiated

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三峡上游支流梁滩河底泥重金属分布及稳定化

同济大学学报（自然科学版） 2013年第10期41卷 1519-1525页

作者：柴晓利侯琳琳同济大学环境科学与工程学院上海200092 同济大学污染控制与资源化研究国家重点实验室上海200092

以梁滩河河道底泥为研究对象,对不同监测断面39个底泥样品的重金属含量及分布进行了测定,同时选取其中5个底泥样品,利用纳米铁粉对底泥中重金属进行了稳定化处理,并通过X射线衍射仪(XRD)对其稳定化机理进行了探讨.研究结果表明,梁滩河... 详细信息

以梁滩河河道底泥为研究对象,对不同监测断面39个底泥样品的重金属含量及分布进行了测定,同时选取其中5个底泥样品,利用纳米铁粉对底泥中重金属进行了稳定化处理,并通过X射线衍射仪(XRD)对其稳定化机理进行了探讨.研究结果表明,梁滩河底泥已经不同程度地受到了Cu,Pb,As,Zn,Cd,Cr等重金属的污染,其中As的污染程度最严重,最高值达到了土壤背景值的110倍.添加纳米铁粉稳定化试剂后,As,Zn,Pb,Cr,Cu,Hg等重金属的浸出浓度都得到了较大程度的降低;XRD分析结果表明,添加纳米铁后,重金属的化学形态由游离态转变为稳定态是重金属浸出浓度降低的主要原因之一.

关键词：底泥重金属浸出毒性稳定化

Comparative population genomics dissects the genetic basis of seven domestication traits in jujube

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Horticulture Research 2020年第1期7卷 1769-1782页

作者： Mingxin Guo Zhongren Zhang Yanwei Cheng Sunan Li Peiyin Shao Qiang Yu Junjie Wang Gan Xu Xiaotian Zhang Jiajia Liu linlin hou Hanxiao Liu Xusheng Zhao College of Life Sciences Luoyang Normal UniversityLuoyang 471934China Jujube Research Center Luoyang Normal UniversityLuoyang 471934China Novogene Bioinformatics Institute Beijing 100083China

Jujube(Ziziphus jujuba Mill.)is an important perennial fruit tree with a range of interesting horticultural *** was domesticated from wild jujube(Ziziphus acidojujuba),but the genomic variation dynamics and genetic changes underlying its horticultural traits during domestication are poorly ***,we report a comprehensive genome variation map based on the resequencing of 350 accessions,including wild,semi-wild and cultivated jujube plants,at a>15×*** the combination of a genome-wide association study(GWAS)and selective sweep analysis,we identified several candidate genes potentially involved in regulating seven domestication traits in *** fruit shape and kernel shape,we integrated the GWAS approach with transcriptome profiling data,expression analysis and the transgenic validation of a candidate gene to identify a causal gene,ZjFS3,which encodes an ethyleneresponsive transcription ***,we identified a candidate gene for bearing-shoot length and the number of leaves per bearing shoot and two candidate genes for the seed-setting rate using *** the selective sweep analysis,we also discovered several putative genes for the presence of prickles on bearing shoots and the postharvest shelf life of fleshy *** study outlines the genetic basis of jujube domestication and evolution and provides a rich genomic resource for mining other horticulturally important genes in jujube.

关键词： jujube traits mining