检索结果-南通市图书馆

The genomic and immunogenomic landscape of mechanics pathway informs clinical prognosis and response to mechanotherapy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第8期67卷 1549-1562页

作者： Peidong Zhang Peiwei Li Muya Tang Ryan CGimple Liang Huang Jing yue Qiuhong Shen Yiwei Du Qian Zhang Zhengnan Yang Haihuai He Kailin Yang linjie Zhao Shengtao Zhou Department of Obstetrics and Gynecology Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOEState Key Laboratory of BiotherapyWest China Second HospitalSichuan University and Collaborative Innovation CenterChengdu 610041China Physician Scientist Training Program Department of MedicineWashington University School of MedicineSt.Louis 63110USA Department of Neurosurgery State Key Laboratory of BiotherapyWest China HospitalSichuan University and Collaborative Innovation CenterChengdu 610041China Department of Radiation Oncology Taussig Cancer CenterCleveland ClinicCleveland 44106USA

Mechanics shape cell and tissue plasticity and maintain their *** cancers,mechanical signals regulate cancer hallmarks via mechanotransduction pathways,such as proliferation,metastasis and metabolic ***,comprehensive characterization of mechanotransduction pathway genes and their clinical relevance across different cancer types remains ***,we systematically portrayed the alterations of mechanotransduction pathway genes across 31 cancer types using The Cancer Genome Atlas(TCGA)*** the cancer types could be categorized into 6 subtypes based upon the transcriptional pattern of mechanics pathway *** subtype has its own unique molecular expression pattern,mutation landscapes,immune infiltrates,and patient clinical *** further found that the responses of two subtypes of cancers,one with the optimal outcome and the other with the worst prognosis,to a classical mechanotherapeutic agent(Fasudil,RhoA/ROCK inhibitor)were totally different,indicating that our cancer stratification system based upon mechanotransduction pathway genes could inform clinical responses of patients to mechanotherapeutic ***,our study provides a novel pan-cancer landscape of the mechanotransduction pathways and underscores its potential clinical significance in the prediction of clinical prognosis and therapeutic responses to mechanotherapy among cancer patients.

关键词： pan-cancer cancer mechanics multi-omics immunology

在线全文

学校读者我要写书评

暂无评论

孔金属化设计对高温共烧陶瓷基板热阻的影响

半导体技术 2024年第9期49卷 867-872页

作者：刘林杰李杰郝跃西安电子科技大学微电子学院西安710126 中国电子科技集团公司第十三研究所石家庄050051

高温共烧陶瓷(HTCC)基板广泛应用于电子封装领域,其热阻是一个重要指标。围绕Al_(2)O_(3)和AlN陶瓷基板,探究在不同金属化孔间距和布局下的热阻规律。建立了陶瓷基板热传递有限元模型,并对其热阻进行仿真。制备了两种陶瓷基板,测试了其... 详细信息

高温共烧陶瓷(HTCC)基板广泛应用于电子封装领域,其热阻是一个重要指标。围绕Al_(2)O_(3)和AlN陶瓷基板,探究在不同金属化孔间距和布局下的热阻规律。建立了陶瓷基板热传递有限元模型,并对其热阻进行仿真。制备了两种陶瓷基板,测试了其在不同功率负载下的热阻。测试结果表明,相同规格的AlN陶瓷基板的热阻约为Al_(2)O_(3)的25%;Mo孔金属化对Al_(2)O_(3)陶瓷基板的散热能力有明显提升作用,孔密度越大,基板热阻越低;而不同W金属化孔密度下的AlN基板热阻没有显著差异。仿真结果与实测结果基本吻合,为陶瓷基板的热设计提供了参考。

关键词：陶瓷基板高温共烧陶瓷(HTCC) 热阻热设计孔金属化

Cascading V_(2)O_(3)/N-doped carbon hybrid nanosheets as high-performance cathode materials for aqueous zinc-ion batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2022年第3期33卷 1430-1434页

作者： yue Niu Denghui Wang Yingjie Ma linjie Zhi CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100039China

In recent years, especially when there is increasing concern about the safety issue of lithium-ion batteries (LIBs), aqueous Zn-ion batteries (ZIBs) have been getting a lot of attention because of their cost-effectiveness, materials abundance, high safety, and ecological friendliness. Their working voltage and specific capacity are mainly determined by their cathode materials. Vanadium oxides are promising cathode materials for aqueous ZIBs owing to their low cost, abundant resources, and multivalence. However, vanadium oxide cathodes still suffer from unsatisfactory capacity, poor stability, and low electrical conductivity. In this work, cascading V_(2)O_(3)/nitrogen doped carbon (V_(2)O_(3)/NC) hybrid nanosheets are prepared for high-performance aqueous ZIBs by pyrolyzing pentyl viologen dibromide (PV) intercalated V_(2)O5 nanosheets. The unique structure features of V_(2)O_(3)/NC nanosheets, including thin sheet-like morphology, small crystalline V_(2)O_(3) nanoparticles, and conductive NC layers, endow V_(2)O_(3)/NC with superior performance compared to most of the reported vanadium oxide cathode materials for aqueous ZIBs. The V_(2)O_(3)/NC cathode exhibits the discharge capacity of 405 mAh/g at 0.5 A/g, excellent rate capability (159 mAh/g at 20 A/g), and outstanding cycling stability with 90% capacity retention over 4000 cycles at 20 A/g.

关键词： Aqueous zinc ion batteries Cathode materials Vanadium oxides Nitrogen doped carbon 2D nanosheets High performance

Viologens-based redox mediators with tunable HOMO–LUMO energy gap for highly effective hydrogen peroxide electrosynthesis

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第12期16卷 12936-12941页

作者： Yang Gao Xiaohui Xu yue Niu Xinran Hu Zeyu Li Longkun Yang linjie Zhi Bin Wang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China The Beijing Key Laboratory for Nano-Photonics and Nano-Structure(NPNS) Department of PhysicsCapital Normal UniversityBeijing 100048China College of New Energy China University of Petroleum(East China)Qingdao 266580China

In comparison with the developing nano-carbon catalysts,some small organic molecules are also emerging as catalysts with typical features,however,their working mechanism is still ***,we synthesized a series of viologen-based heterogeneous catalysts with the same molecular skeleton but different substituent groups through anion exchange *** viologen-based molecules were used as a model catalyst to investigate the underlying structure–function relationship for small molecules-based H_(2)O_(2) *** from the commonly reported carbon-based electrocatalysts,viologens can produce H_(2)O_(2) in a synergistic manner,which means that viologens can not only directly catalyze oxygen reduction but also serve as a redox *** found that the ring current and H_(2)O_(2) selectivity of viologens deliver an increasing trend with the increase of the alkyl chain length of alkyl-substituted viologens and further increase when using benzyl as the substituent *** a result,a benzyl-substituted viologen(BV)delivers the best electrocatalytic performance among the samples,including the highest H_(2)O_(2) selectivity of 96.9%at 0.6 V and the largest ring current density of about 13.6 mA·***,density functional theory(DFT)calculations disclose that the carbon atoms bonded with positively charged N are the active sites and the small highest occupied molecular orbital(HOMO)–lowest unoccupied molecular orbital(LUMO)energy gap of BV is beneficial to the synergistic mechanism for H_(2)O_(2) *** work sheds new insight into the efficient H_(2)O_(2) production in a synergistic manner for small molecules-based electrocatalysts.

关键词： viologens electrocatalysis hydrogen peroxide redox mediator oxygen reduction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高精度薄厚膜异构HTCC基板制备工艺

微纳电子技术 2024年第7期61卷 150-155页

作者：张鹤杨鑫谢岳杨振涛刘林杰中国电子科技集团公司第十三研究所石家庄050051

针对高温共烧陶瓷(HTCC)基板高平整度、高密度封装需求,提出了一种高精度薄厚膜异构HTCC基板的制备方法,并对其关键工艺进行研究。结合陶瓷基板精密研磨工艺与薄膜制备工艺,该方法在大幅降低原有HTCC基板的平面度、粗糙度的同时,实现HTC... 详细信息

针对高温共烧陶瓷(HTCC)基板高平整度、高密度封装需求,提出了一种高精度薄厚膜异构HTCC基板的制备方法,并对其关键工艺进行研究。结合陶瓷基板精密研磨工艺与薄膜制备工艺,该方法在大幅降低原有HTCC基板的平面度、粗糙度的同时,实现HTCC表面精密布线。测量结果表明,薄厚膜HTCC基板的平面度低至15μm,表面布线最小线宽低至10μm,与传统陶瓷基板平面度(30μm)与最小线宽(50μm)相比均有较大改善。在此基础上,研究了不同种子层厚度对薄厚膜异构HTCC基板结合力的影响。结果表明当钛钨层厚度为150 nm时,薄膜层和陶瓷基板结合力高达9.27 gf(1 gf=0.0098 N)。

关键词：多层共烧陶瓷薄膜金属化封装基板异构集成键合强度

在线全文

学校读者我要写书评

暂无评论

外调制倍频光生毫米波技术的研究进展

激光杂志 2024年第7期45卷 9-15页

作者：胡文光邵宇丰王安蓉陈超杨林婕李文臣柳海楠靳清清岳京歌张颜鹭重庆三峡学院电子与信息工程学院重庆404100

目前,随着光电子芯片技术的高速发展,高频毫米波通信已成为目前宽带接入网络中的重要发展技术;因为采用外调制倍频方案的光生毫米波系统兼具收发毫米波信号的高效性和稳定性,且能充分利用现有电信网络中的光纤资源,因此,在实际中具备潜... 详细信息

目前,随着光电子芯片技术的高速发展,高频毫米波通信已成为目前宽带接入网络中的重要发展技术;因为采用外调制倍频方案的光生毫米波系统兼具收发毫米波信号的高效性和稳定性,且能充分利用现有电信网络中的光纤资源,因此,在实际中具备潜在应用价值。综述了光生毫米波倍频基本原理、典型倍频仿真或实验方案及其相关测试结果的研究进展;考虑到马赫-曾德尔调制器(Mach-Zehnder Modulator,MZM)作为倍频光生毫米波的关键电光器件,因此,分析了其中的关键工作参数;最后,对光载无线通信(Radio over Fiber,RoF)系统中光生毫米波技术的应用前景进行了展望。

关键词：光载无线通信光生毫米波倍频马赫-曾德尔调制器

夜间增温对灌浆期高温胁迫下小麦干物质及灌浆特性的影响

在线全文

学校读者我要写书评

暂无评论

麦类作物学报 2024年第5期44卷 626-638页

作者：张月贺威崔国际王鸣燕秦博雅曹金婷陶景雯汪林洁黄正来张文静马尚宇樊永惠安徽农业大学农学院/农业部黄淮南部小麦生物学与遗传育种重点实验室安徽合肥230036

为了解灌浆期高温胁迫下小麦生产力对不同阶段夜间增温的反应,以对温度敏感性不同的两个小麦品种扬麦18(春性品种)和烟农19(半冬性品种)为试验材料,采用可移动塑料增温棚,于2021-2022年对小麦进行不同阶段夜间增温[分蘖期-拔节期增温(W ... 详细信息

为了解灌浆期高温胁迫下小麦生产力对不同阶段夜间增温的反应,以对温度敏感性不同的两个小麦品种扬麦18(春性品种)和烟农19(半冬性品种)为试验材料,采用可移动塑料增温棚,于2021-2022年对小麦进行不同阶段夜间增温[分蘖期-拔节期增温(W T-J N)、拔节期-孕穗期增温(W J-B N)和孕穗期-开花期增温(W B-A N)]及灌浆期高温胁迫处理,比较分析了不同处理下小麦干物质积累及灌浆特性的差异。结果表明,W T-J N和W J-B N处理主要通过缩短小麦播种-开花的时长,延长灌浆期天数,增加花前干物质转运量、花后干物质积累量和花后干物质积累贡献率,进而提高了开花期和成熟期干物质积累量;促进了干物质在成熟期穗轴+颖壳和籽粒中的积累,降低了小麦茎鞘+叶片中的积累量,增产3.08%~7.62%。灌浆期高温胁迫显著降低了两个品种的产量,而与灌浆期高温胁迫处理(NH)相比,W T-J H和W J-B H处理增产1.21%~6.05%。与不增温处理(NN)相比,在W T-J N和W J-B N处理下两个小麦品种的灌浆期粒重及灌浆速率均提高,W B-A N和NH处理则降低了小麦灌浆参数。这说明分蘖期-拔节期和拔节期-孕穗期夜间增温可提高小麦开花期和成熟期的干物质积累量,促进小麦籽粒灌浆,缓解灌浆期高温胁迫对小麦生产力的不利影响,有助于小麦产量形成。

关键词：夜间增温灌浆期高温胁迫小麦干物质积累与分配灌浆特性

多输入多输出可见光通信系统中预编码技术的研究进展

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

激光杂志 2024年第6期45卷 21-27页

作者：陈超邵宇丰王安蓉胡文光柳海楠李文臣杨林婕张颜鹭岳京歌靳清清重庆三峡学院电子与信息工程学院重庆404100

近年来,可见光通信(VLC)技术得到飞速发展,该技术兼具室内低功耗照明和宽带信号高速接入的双重功能,因此在室内大数据通信领域具有较高的应用价值。多输入多输出(MIMO)作为一种在VLC系统中能实现信道容量倍增的技术正日益引起业界关注,... 详细信息

近年来,可见光通信(VLC)技术得到飞速发展,该技术兼具室内低功耗照明和宽带信号高速接入的双重功能,因此在室内大数据通信领域具有较高的应用价值。多输入多输出(MIMO)作为一种在VLC系统中能实现信道容量倍增的技术正日益引起业界关注,但多信道具有强相关性容易导致用户间信息串扰,而在发射机中应用若干预编码技术可在一定程度上避免用户间信息干扰,且可以较低成本实现系统收发质量的提升。文章综述了MIMO-VLC系统中预编码技术的应用背景和基本原理,总结了典型线性及非线性预编码技术的研究进展,讨论并分析了该类技术的应用优势、发展趋势和面临的挑战。

关键词：可见光通信系统预编码线性非线性人工智能

DC-55 GHz高性能焊球阵列封装用非垂直互连结构

在线全文

学校读者我要写书评

暂无评论

光学精密工程 2023年第3期31卷 363-370页

作者：刘林杰郝跃周扬帆王轲乔志壮西安电子科技大学陕西西安710000 中国电子科技集团公司第十三研究所封装专业部河北石家庄050000 中国电子科技集团公司第十三研究所河北石家庄050000

根据5G信号对通道带宽的要求,通过研究陶瓷基板中“类同轴”互连的微波特性,设计了一种新型非垂直互连结构,通过陶瓷介电层之间金属化通孔的错位设计,改善垂直过孔与水平传输线转弯处的阻抗突变,更有利于高频信号的传输,进一步扩展带宽... 详细信息

根据5G信号对通道带宽的要求,通过研究陶瓷基板中“类同轴”互连的微波特性,设计了一种新型非垂直互连结构,通过陶瓷介电层之间金属化通孔的错位设计,改善垂直过孔与水平传输线转弯处的阻抗突变,更有利于高频信号的传输,进一步扩展带宽。分析了错位角度、阶梯级数、焊球半径和焊球间距对传输性能的影响,设计并实现了宽带低损耗互连陶瓷基板。测试结果表明,该结构的最高应用频率可达55 GHz,在DC-55 GHz频带内插入损耗小于1.5 dB,回波损耗大于15 dB,同时利用实测数据进行信号传输验证,结果表明在未引入预加重、均衡的情况下即可满足56 G/112 G NRZ,112 G PAM4高速信号的传输。

关键词：无线通信 5G 高速陶瓷基板类同轴预加重