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Dynamical Interaction Between Information and Disease Spreading in Populations of Moving Agents

Computers, Materials & Continua 2018年第10期57卷 123-144页

作者： lingling xia Bo Song Zhengjun Jing Yurong Song Liang Zhang Department of Computer Information and Cyber Security Jiangsu Police InstituteNanjing210031China College of Telecommunications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing210003China Global Big Data Technologies Centre University of Technology SydneySydney2007Australia College of Computer Engineering Jiangsu University of TechnologyChangzhou213001China College of Automation Nanjing University of Posts and TelecommunicationsNanjing210003China

Considering dynamical disease spreading network consisting of moving individuals,a new double-layer network is constructed,one where the information dissemination process takes place and the other where the dynamics of disease spreading *** the basis of Markov chains theory,a new model characterizing the coupled dynamics between information dissemination and disease spreading in populations of moving agents is established and corresponding state probability equations are formulated to describe the probability in each state of every node at each *** Carlo simulations are performed to characterize the interaction process between information and disease spreading and investigate factors that influence spreading *** results show that the increasing of information transmission rate can reduce the scale of disease spreading in some *** infection period and strengthening consciousness for self-protection by decreasing individual’s scope of activity both can effectively reduce the final refractory density for the disease but have less effect on the information *** addition,the increasing of vaccination rate or decreasing of long-range travel can also reduce the scale of disease spreading.

关键词： Complex networks Markov chains theory interaction process spreading dynamics double-layer network

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Recent advances in autonomous synthesis of materials

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ChemPhysMater 2022年第2期1卷 77-85页

作者： Yucen Li lingling xia Yiming Fan Qinyue Wang Ming Hu School of Physics and Electronic Science East China Normal UniversityShanghai 200241China

The synthesis of materials has been an important task throughout human history,and the ability to perform successful and efficient syntheses has been a factor in industrial revolutions and societal ***,the rapid development of sophisticated techniques such as flow synthesis methods,artificial intelligence,infor-mation technology,and robotics,has facilitated the autonomous synthesis of chemicals with minimal effort and at little cost to the *** trend has influenced recent materials research and could potentially reduce the time from discovery of materials to their *** this short review,we focus on the autonomous synthesis of *** first discuss how autonomous synthesis could change materials ***,we provide some examples of autonomous syntheses in flow ***,we present examples of autonomous syntheses using non-flow methods.

关键词： Autonomous synthesis Machine learning Flow chemistry Quantum dots Metal-organic frameworks Perovskite

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Automated synthesis of gadopentetate dimeglumine through solid-liquid reaction in femtosecond laser fabricated microfluidic chips

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Chinese Chemical Letters 2022年第2期33卷 1077-1080页

作者： Difeng Yin Yucen Li lingling xia Wenbo Li Wei Chu Jianping Yu Miao Wu Ya Cheng Ming Hu State Key Laboratory of High Field Laser Physics and CAS Center for Excellence in Ultra-intense Laser Science Shanghai Institute of Optics and Fine Mechanics(SIOM)Chinese Academy of Sciences(CAS)Shanghai 201800China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China School of Physical Science and Technology ShanghaiTech UniversityShanghai 200031China XXL–The Extreme Optoelectromechanics Laboratory School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China

Despite the continuously increased requirement on automated synthesis of medicines for distributed manufacturing and personal care, it remains a challenge to realize automated synthesis which requires solid-liquid phase reactions. In this work, we demonstrated an automated solid-liquid synthesis for gadopentetate dimeglumine, the most widely used magnetic resonance imaging(MRI) contrast agent. The high-efficiency reaction was performed in a 3D microfluidic chip which was fabricated by femtosecond laser micromachining. The structure of the chip realized 3D shear flow which was essential for highly efficient mixing and movement of the solid-liquid mixtures. Ultraviolet visible(UV-vis) spectrometer was employed for in-line analysis to help automation of this system. Comparing with the round-bottom flask system, this synthetic system showed significantly higher reaction rate, indicating the advantage of the3D microfluidic technology in micro chemical engineering.

关键词： Automated synthesis Femtosecond laser micromachining Microfluidics MRI imaging UV–vis absorption spectrum

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Efficient synthesis of vitamin D_(3) in a 3D ultraviolet photochemical microreactor fabricated using an ultrafast laser

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Light(Advanced Manufacturing) 2024年第1期5卷 73-81页

作者： Aodong Zhang Jian Xu lingling xia Ming Hu Yunpeng Song Miao Wu Ya Cheng Engineering Research Center for Nanophotonics and Advanced Instrument School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China XXL—The Extreme Optoelectromechanics Laboratory School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China

Large-scale,high-precision,and high-transparency microchannels hold great potential for developing high-performance continuous-flow photochemical *** demonstrated ultrafast laser-enabled fabrication of three-dimensional microchannel reactors in ultraviolet(UV)grade fused silica which exhibit high transparency under the illumination of UV light sources of wavelengths well below 300 nm with excellent mixing *** the fabricated glass microchannel reactors,we demonstrated continuous-flow photochemical synthesis of vitamin D_(3) with UV LED array light sources.

关键词： Ultrafast laser microfabrication Fused silica microchannels UV photochemical reactors Continuousflow synthesis Vitamin D_(3)

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Automated and remote synthesis of poly(ethylene glycol)-mineralized ZIF-8 composite particles via a synthesizer assisted by femtosecond laser micromachining

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Chinese Chemical Letters 2022年第1期33卷 497-500页

作者： Miao Wu lingling xia Yucen Li Difeng Yin Jianping Yu Wenbo Li Ning Wang Xin Li Jiwei Cui Wei Chu Ya Cheng Ming Hu School of Physics and Electronic Science East China Normal UniversityShanghai 200241China State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241 China XXL–The Extreme Optoelectromechanics Laboratory School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241 China State Key Laboratory of High Field Laser Physics and CAS Center for Excellence in Ultra-intense Laser Science Shanghai Institute of Optics and Fine Mechanics(SIOM)Chinese Academy of Sciences(CAS)Shanghai 201800China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education School of Chemistry and Chemical EngineeringShandong UniversityJi'nan 250100China

Mineralization of the ZIF-8 in the presence of biomacromolecules has been demonstrated to be a general way for making bioentities@ZIFs *** ZIF-8 crystals permit controlled storage and utilization of the bioentities,thus can benefit drug delivery,cold-chain breaking *** the increasing needs on personal care and distributed manufacturing,automated synthesis controlled by a computer becomes the next *** this work,we designed an automatic synthesis system to prepare PEG mineralized ZIF-8 composite *** system is based on flow chemistry with the microfluidic chips fabricated by femtosecond laser *** particles were synthesized and monitored ***,this synthesizer could be extended for fabrication of vaccine particles under remote control through internet.

关键词： ZIF-8 Automatic synthesis Remote synthesis MOFs Vaccine particles Microfluidic chip Flow chemistry

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Comprehensive Strategy for Keloid Treatment:Experience at Shanghai Ninth People's Hospital

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Chinese Journal of Plastic and Reconstructive Surgery 2020年第2期2卷 88-92页

作者： xiaoli WU Yating YANG Wei LIU Wenbo WANG lingling xia xiaoqing WANG Qiong ZHAO Zhen GAO Department of Plastic and Reconstructive Surgery Shanghai 9th People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiP.R.China

Keloids are a notorious fibroproliferative disorder that may cause cosmetic concerns and life *** methods such as surgery,injection,and laser have been used;however,single treatments are at risk of recurrence;therefore,comprehensive therapy is the better ***,we focused on the management of different medical interventions according to subjective and objective conditions of keloid patients and summarized several clinical comprehensive strategies based on our clinical *** original concept of laser combined with radiotherapy was also introduced as a promising method,especially for wide-based pathological scars.

关键词： keloids hypertrophic scar comprehensive treatment laser radiotherapy injection surgery

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聚苯并咪唑(PBI)渗透汽化膜的研究进展

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膜科学与技术 2014年第5期34卷 116-124页

作者：夏玲玲王艳华中科技大学化学与化工学院武汉430074

聚苯并咪唑(PBI,polybenzimidazole)是一种高性能芳香族聚合物材料.由于具有突出的耐化学性、热稳定性和机械性能,以及良好的亲水性和可纺性,PBI成为一种很有前途的渗透汽化分离膜材料.本文综述用于渗透汽化的PBI分离膜的研究进展,扼要... 详细信息

聚苯并咪唑(PBI,polybenzimidazole)是一种高性能芳香族聚合物材料.由于具有突出的耐化学性、热稳定性和机械性能,以及良好的亲水性和可纺性,PBI成为一种很有前途的渗透汽化分离膜材料.本文综述用于渗透汽化的PBI分离膜的研究进展,扼要介绍PBI渗透汽化膜几种不同的形态,包括致密平板膜、单层中空纤维膜、双层中空纤维膜以及混合基质膜,并对不同形态的PBI膜进行对比;同时也阐述分析了交联、表面改性、共混、填充等多种改性方法以及其对膜分离性能的影响.基于上述讨论,本文最后对PBI渗透汽化膜的发展方向和研究前景进行了总结.

关键词： PBI膜渗透汽化分离改性膜形态

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福州市城市化进程与大气污染关系研究

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环境污染与防治 2015年第5期37卷 44-49页

作者：高明郭施宏夏玲玲福州大学经济与管理学院福建福州350108

以福州市为研究区域,选取福州市1996—2012年的时间序列数据,将大气污染物浓度作为被解释变量,城市化水平作为解释变量,分别设定二次曲线模型和三次曲线模型,通过比较PM10、SO2、NO2浓度与城市化水平的二次曲线和三次曲线模型的回归拟... 详细信息

以福州市为研究区域,选取福州市1996—2012年的时间序列数据,将大气污染物浓度作为被解释变量,城市化水平作为解释变量,分别设定二次曲线模型和三次曲线模型,通过比较PM10、SO2、NO2浓度与城市化水平的二次曲线和三次曲线模型的回归拟合效果,得出福州市大气污染与城市化水平之间的演化规律。结果表明,1996—2012年,福州市城市化水平平稳上升,城市的大气污染程度与城市化水平之间的关系并不完全符合"倒U型"的环境库兹涅茨曲线,不同的污染物类型具有不同的演化规律。PM10、SO2与城市化水平呈"倒N型"的曲线关系;NO2与城市化水平之间呈现"倒U型"曲线关系。由于研究的时间序列较短,因而研究结果可能只是真实曲线的一部分,福州市的大气污染与城市化水平之间的关系还有待进一步研究。

关键词：城市化大气污染环境库兹涅茨曲线熵值评价法福州市

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基于静态结构的恶意代码同源性分析

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计算机工程与应用 2017年第14期53卷 93-98页

作者：陈琪蒋国平夏玲玲南京邮电大学计算机学院南京210003 南京邮电大学自动化学院南京210003 南京邮电大学通信与信息工程学院南京210003

由于变种和多态技术的出现,恶意代码的数量呈爆发式增长。然而涌现的恶意代码只有小部分是新型的,大部分仍是已知病毒的变种。针对这种情况,为了从海量样本中筛选出已知病毒的变种,从而聚焦新型未知病毒,提出一种改进的判定恶意代码所... 详细信息

由于变种和多态技术的出现,恶意代码的数量呈爆发式增长。然而涌现的恶意代码只有小部分是新型的,大部分仍是已知病毒的变种。针对这种情况,为了从海量样本中筛选出已知病毒的变种,从而聚焦新型未知病毒,提出一种改进的判定恶意代码所属家族的方法。从恶意代码的行为特征入手,使用反汇编工具提取样本静态特征,通过单类支持向量机筛选出恶意代码的代表性函数,引入聚类算法的思想,生成病毒家族特征库。通过计算恶意代码与特征库之间的相似度,完成恶意代码的家族判定。设计并实现了系统,实验结果表明改进后的方法能够有效地对各类家族的变种进行分析及判定。

关键词：恶意代码单类支持向量机静态分析聚类

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区块链在PKI安全中的应用研究

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计算机科学与探索 2024年第10期18卷 2573-2593页

作者：夏玲玲王群马卓梁广俊江苏警官学院计算机信息与网络安全系南京210031 江苏省电子数据取证分析工程研究中心南京210031

重应用、轻防御的设计思想致使传输控制协议/网际协议(TCP/IP)体系结构设计之初就缺乏内生安全属性,使得公钥基础设施(PKI)作为实现互联网不同实体之间通信真实性、完整性、机密性和不可抵赖性的安全治理权威架构自提出以来就备受关注,... 详细信息

重应用、轻防御的设计思想致使传输控制协议/网际协议(TCP/IP)体系结构设计之初就缺乏内生安全属性,使得公钥基础设施(PKI)作为实现互联网不同实体之间通信真实性、完整性、机密性和不可抵赖性的安全治理权威架构自提出以来就备受关注,同时PKI自身因其中心化机制带来的单点故障和单一信任等安全威胁也成为近年来研究者关注的热点。随着区块链技术逐渐应用于信息安全领域,利用区块链的去中心化、分布式账本、防篡改、公开透明等特点来解决原生PKI及其演进过程中出现的各类安全问题成为一个研究方向和重点。根据PKI技术的发展及区块链技术的应用,将解决原生PKI安全的方法分为以信任网络(WoT)技术和证书透明度(CT)机制为主的不依赖区块链的解决方案,保留认证机构(CA)核心功能的融入区块链技术的中心化PKI方案,以及用区块链完全替代CA功能的基于区块链的去中心化PKI方案。介绍了原生PKI的安全现状,讨论了分别利用WoT技术和CT机制对原生PKI的安全性进行改造的具体方法,重点分析了融入区块链技术的中心化PKI以及基于区块链的去中心化PKI的设计思想,并分别选择了部分典型应用场景就其实现方法和应用特点进行了有针对性的剖析,对区块链在PKI安全中的应用研究进行了展望。

关键词：区块链公钥基础设施网络安全证书管理认证机构

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