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金黄色葡萄球菌对红霉素和克林霉素诱导耐药分析

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检验医学 2010年第9期25卷 675-677页

作者：孙建文万新亮任孔华鲍玲玲代龙韩正周方晓云姜小华解放军第八五医院检验科上海200052

目的探讨金黄色葡萄球菌临床分离株对红霉素和克林霉素的耐药性,检测红霉素对克林霉素诱导耐药的发生率。方法采用美国临床实验室标准化研究所(CLSI)推荐的纸片扩散法,检测耐甲氧西林金黄色葡萄球菌(MRSA)以及金黄色葡萄球菌对红霉素和... 详细信息

目的探讨金黄色葡萄球菌临床分离株对红霉素和克林霉素的耐药性,检测红霉素对克林霉素诱导耐药的发生率。方法采用美国临床实验室标准化研究所(CLSI)推荐的纸片扩散法,检测耐甲氧西林金黄色葡萄球菌(MRSA)以及金黄色葡萄球菌对红霉素和克林霉素的耐药性,并以双纸片法(即D试验)分析红霉素对克林霉素诱导耐药表型。结果金黄色葡萄球菌中MRSA占77.2%。金黄色葡萄球菌对红霉素及克林霉素同时耐药菌株占62.4%,红霉素耐药而克林霉素敏感菌株占21.5%。红霉素耐药而克林霉素敏感的MRSA和甲氧西林敏感金黄色葡萄球菌(MSSA)中D试验阳性分别为72.0%和57.1%。D试验阳性占红霉素耐药而克林霉素敏感金黄色葡萄球菌的68.8%。结论临床微生物实验室应常规开展D试验,检测金黄色葡萄球菌中红霉素对克林霉素的诱导耐药性,以指导临床医师合理选用大环内酯类、林可酰胺类抗菌药物。

关键词：金黄色葡萄球菌红霉素克林霉素诱导耐药

The Impact of Large-Scale Reclamation on Hydro-Dynamic Environment--A Case Study of Xinghua Bay

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Journal of Ocean University of China 2016年第4期15卷 583-592页

作者： YU Jing bao Xianwen DING Yang ZHANG Wei ZHOU lingling College of Physical and Environmental Oceanography Ocean University of China Qingdao 266100 P. R. China Physical Oceanography Laboratory/Qingdao Collaborative Innovation Center of Marine Science and Technology Ocean University of China Qingdao 266100 P. R. China Qingdao Marine Geological Engineering Investigation Institute Qingdao 266071 P. R. China

A hydro-dynamic model is established on basis of MIKE21 FM to simulate the hydro-dynamic characteristics of Xinghua Bay and investigate the influence of reclamation project on the tidal elevation and tidal currents. Tidal elevation data was obtained at the six tide gauge stations around the Xinghua Bay, and another six current stations were established to observe the tidal current velocity and direction. Validation shows that the model-simulated tidal elevation and tidal currents agree well with observations made at different stations. Predictions are made according to the reclamation project proposed in the regional marine planning of Hanjiang Industrial Park around the port in Putian City. The variations of hydro-dynamic factors, such as tide, current velocity and direction and tidal influx are obtained, and the adverse effect of reclamation on marine environment is discussed. It is shown that the tidal level inside the Xinghua Bay during high tide decreases after the reclamation project is completed. The tidal currents during flooding tide generally decrease in the southeast of the reclamation region, with the maximum decreasing amplitude reaching 0.44 m s^(-1). On the other hand, the tidal currents during flooding tide increase around the southeast and southwest corners of the reclamation region. The tidal currents during ebb tide increase around the southeast and southwest corners of the reclamation region, with the maximum increasing amplitude attaining 0.18 m s^(-1). The results in this paper can give some guidance for the marine environment management and the effective utilization of land in Putian.

关键词： tidal currents southeast flooding southwest corners completed decreasing elevation coastal

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基于邯郸商场人员密度及空调负荷特性研究

河北工程大学学报（自然科学版） 2017年第3期34卷 74-78页

作者：石凯波王景刚鲍玲玲侯松宝赵旭曹辉河北工程大学能源与环境工程学院河北邯郸056000

运用黑箱理论模型对邯郸的两个大型商场进行人流量调研,分析两个商场的人员流动规律,并采用数理统计学相关知识,建立商场人员密度计算模型。结合两个商场实例的调研数据,得出商场人员密度、每天不同时段的人员密度分布规律以及休息日和... 详细信息

运用黑箱理论模型对邯郸的两个大型商场进行人流量调研,分析两个商场的人员流动规律,并采用数理统计学相关知识,建立商场人员密度计算模型。结合两个商场实例的调研数据,得出商场人员密度、每天不同时段的人员密度分布规律以及休息日和工作日的平均人员密度比值。并对邯郸两个商场进行空调冷负荷计算和分析,研究两个商场的冷负荷特点,根据不同的负荷特性,采取相应的措施来减少空调负荷。建议两个商场的空调系统应在提高新风品质,提高新风利用率等方面进行优化。

关键词：黑箱理论商场人员密度冷负荷优化建议新风

Pore Structure and Permeability Characterization of Highrank Coal Reservoirs: A Case of the Bide-Santang Basin, Western Guizhou, South China

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Acta Geologica Sinica(English Edition) 2020年第2期94卷 243-252页

作者： GUO Chen QIN Yong MA Dongmin XIA Yucheng bao Yuan CHEN Yue LU lingling College of Geology and Environment Xi'an University of Science and TechnologyXi'an 710054China Shaanxi Provincial Key Laboratory of Geological Support for Coal Green Exploitation Xi’an 710054China Post-doctoral Research Station of Geological Resources and Geological Engineering Xi'an University of Science and TechnologyXi'an 710054China Geological Research Institute for Coal Green Mining Xi'an Universityof Science and Technology Xi'an 710054China Key Laboratory of Coalbed Methane Resources and Reservoir Formation Process Ministry of EducationChina University of Mining and TechnologyXuzhou 221116China

The methods of nuclear magnetic resonance(NMR)spectroscopy,mercury injection porosimetry(MIP),and gas-water relative permeability(GWRP)were used to reveal the pore structure and permeability characteristics of high-rank coal reservoirs in the Bide-Santang basin,western Guizhou,South China,to provide guidance for coalbed methane(CBM)exploration and exploitation and obtain direct insights for the development of CBM *** results indicate that the coal reservoirs in the study area are characterized by well-developed adsorption pores and poorly developed seepage *** bimodal NMR transverse relaxation time(T2)spectra and the mutation in the fractal characteristic of the MIP pore volume indicate poor connectivity between the adsorption pores and the seepage *** a result,the effective porosity is relatively low,with an average of 1.70%.The irreducible water saturation of the coal reservoir is relatively high,with an average of 66%,leading to a low gas relative permeability under irreducible water *** is the main reason for the low recovery of high-rank CBM reservoirs,and effective enhanced CBM recovery technology urgently is *** a nondestructive and less time-consuming technique,the NMR is a promising method to quantitatively characterize the pores and fractures of coals.

关键词： coalbed methane reservoir characterization pore structure relative permeability nuclear magnetic resonance

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地表水源热泵取排水口布置形式的影响研究

人民珠江 2015年第6期36卷 21-24页

作者：胡秋明王景刚鲍玲玲闫丽红于韶山河北工程大学城市建设学院河北邯郸056038

针对邯郸某一项目的地表水源热泵设计中的取排水口形式设置问题,建立了二维湍流模型,采用数值模拟的方法,考虑到地表水源热泵系统与水环境之间的双向影响,研究了地表水源热泵排水口与河岸的角度和取排水口距离对温排水热扩散的影响,并... 详细信息

针对邯郸某一项目的地表水源热泵设计中的取排水口形式设置问题,建立了二维湍流模型,采用数值模拟的方法,考虑到地表水源热泵系统与水环境之间的双向影响,研究了地表水源热泵排水口与河岸的角度和取排水口距离对温排水热扩散的影响,并计算了不同取排水形式下系统的COP(性能系数,Coefficient of Performance)。结果表明:随着排水与河岸角度的增大,取水口区域平均水温升高,同时地表水源热泵的COP呈下降趋势。综合比较水体热污染情况以及热泵系统性能得知:排水口与河岸的角度设置成50°~60°较为合适。

关键词：地表水源热泵水环境排水形式水体热污染 COP

Emerging catalytic materials for practical lithium-sulfur batteries

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Journal of Energy Chemistry 2023年第1期76卷 127-145,I0004页

作者： Fangyi Shi lingling Zhai Qingqing Liu Jingya Yu Shu Ping Lau bao Yu Xia Zheng-Long Xu Department of Industrial and Systems Engineering Department of Applied PhysicsResearch Institute of Advanced Manufacturingthe Hong Kong Polytechnic UniversityHung HomHong Kong SARChina Key Laboratory of Material Chemistry for Energy Conversion and Storage(Ministry of Education) Hubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and Technology(HUST)Wuhan 430074HubeiChina State Key Laboratory of Ultraprecision Machining Technology the Hong Kong Polytechnic UniversityHung HomHong Kong SARChina Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057GuangdongChina

High-energy lithium-sulfur batteries(LSBs)have experienced relentless development over the past decade with discernible improvements in electrochemical ***,a scrutinization of the cell operation conditions reveals a huge gap between the demands for practical batteries and those in the *** sulfur loading,a high electrolyte/sulfur(E/S)ratio and excess anodes for lab-scale LSBs significantly offset their high-energy *** approach practical LSBs,high loading and lean electrolyte parameters are needed,which involve budding challenges of slow charge transfer,polysulfide precipitation and severe shuttle *** track these obstacles,the exploration of electrocatalysts to immobilize polysulfides and accelerate Li-S redox kinetics has been widely ***,this review aims to survey state-of-the-art catalytic materials for practical LSBs with emphasis on elucidating the correlation among catalyst design strategies,material structures and electrochemical *** also statistically evaluate the state-of-the-art catalyst-modified LSBs to identify the remaining discrepancy between the current advancements and the real-world *** closing,we put forward our proposal for a catalytic material study to help realize practical LSBs.

关键词： Lithium-sulfur battery Catalytic materials High sulfur loading Lean electrolyte

西部高寒地区太阳能-地源热泵联合供热系统分析

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能源与节能 2023年第11期 53-58页

作者：苗壮鲍玲玲李建伟张永欢牛国庆罗景辉河北工程大学能源与环境工程学院河北邯郸056038 河北省暖通空调技术创新中心河北邯郸056038

为研究太阳能-地源热泵联合供热系统在西部高寒地区应用的可行性,以榆林市一典型农村住宅为例,利用TRNSYS(Transient System Simulation Program,瞬时系统模拟程序)软件对联合供热系统进行模拟研究。研究结果表明:PV/T-GSHP(Photovoltai... 详细信息

为研究太阳能-地源热泵联合供热系统在西部高寒地区应用的可行性,以榆林市一典型农村住宅为例,利用TRNSYS(Transient System Simulation Program,瞬时系统模拟程序)软件对联合供热系统进行模拟研究。研究结果表明:PV/T-GSHP(Photovoltaic/Thermal-Ground Source Heat Pump,光伏/光热-地源热泵)联合供热系统、ST-GSHP(Solar Thermal-Ground Source Heat Pump,太阳热能-地源热泵)联合供热系统在第20年末的土壤温度相比初始温度分别仅升高1.51℃,1.89℃,传统GSHP(Ground Source Heat Pump,地源热泵)供热系统则降低了3.09℃,年平均系统性能系数分别为4.39,4.62和3.03;ST-GSHP系统与PV/TGSHP系统、GSHP系统和燃煤、燃气、燃油、电热锅炉所消耗的一次能源消耗量相比分别节约5%,36%,60%,50%,34%和49%。2种联合供热系统在该地区均取得较好的供热效果,但ST-GSHP系统供暖模式的运行性能更佳。

关键词：光伏/光热地源热泵 TRNSYS 效益分析

肝细胞癌Wnt信号通路差异表达基因的筛选及意义

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临床肿瘤学杂志 2016年第11期21卷 980-984页

作者：叶映泉朱忠政王亮亮鲍玲玲丛文铭闻炳基安徽医科大学宁波学院解放军第一一三医院肿瘤科浙江宁波315040 第二军医大学东方肝胆外科医院病理科 200438

目的检测肝细胞癌(HCC)中Wnt信号传导通路相关基因的差异表达情况,探讨HCC与该信号通路的关系。方法采用Affymetrix U133 Plus2.0基因芯片检测93例HCC及其配对癌旁组织中78个Wnt信号通路相关基因的mRNA表达差异。结果与癌旁肝组织相比,... 详细信息

目的检测肝细胞癌(HCC)中Wnt信号传导通路相关基因的差异表达情况,探讨HCC与该信号通路的关系。方法采用Affymetrix U133 Plus2.0基因芯片检测93例HCC及其配对癌旁组织中78个Wnt信号通路相关基因的mRNA表达差异。结果与癌旁肝组织相比,HCC组织中TCF19、MMP-12、DKK1、Bcl-9、SFRP4、MMP-1、PYGO2、FZD6、MMP-9、Wnt6共10个基因表达上调,而SFRP1、TCF21、SFRP5、FZD1、Wnt2共5个基因表达下调。其中,TCF19表达上调倍数最多,达9.61倍(P=1.07×10-26)。TCF19表达与FZD1、FZD6、Bcl-9、Wnt6、MMP-1和MMP-12表达呈正相关(均P<0.05)。TCF19表达与肿瘤数目(P=0.017)和分化程度(P=0.046)有关。结论 HCC中存在Wnt信号通路多基因异常表达。下游转录因子TCF19高表达可能是Wnt信号通路激活的关键终末效应,其在HCC中的生物学和病理学意义有待进一步研究。

关键词：肝细胞癌 Wnt信号传导通路差异表达基因寡核苷酸芯片

Adsorption and desorption behavior under coal–water–gas coupling conditions of high- and low-rank coal samples

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Frontiers of Earth Science 2023年第1期17卷 145-157页

作者： Chen GUO Jiang GOU Dongmin MA Yuan bao Qingmin SHI Jiahao MENG Junzhe GAO lingling LU College of Geology and Environment Xi’an University of Science and TechnologyXi’an 710054China Shaanxi Provincial Key Laboratory of Geological Support for Coal Green Exploitation Xi’an 710054China Geological Research Institute for Coal Green Mining Xi’an University of Science and TechnologyXi’an 710054China Aerophoto Grammetry and Remote Sensing Bureau China National Administration of Coal GeologyXi’an 710100China

High-and low-rank coalbed methane(CBM)are both important fields of CBM development in China,but their formation and production mechanisms differ *** adsorption/desorption behavior of high-and low-rank coals under the coupling of coal–water–gas was investigated using two series of *** samples from Zhangjiamao(ZJM)coal mine,Ordos basin,and Sihe(SH)coal mine,Qinshui basin,were tested by isothermal adsorption–desorption experiment,natural imbibition experiment,nuclear magnetic resonance,mercury injection porosimetry,contact angle test,and permeability *** adsorption and desorption experiments under dry,equilibrium water,and saturated water,were performed to explore the differences between the adsorption and desorption *** results show that the wettability and permeability of the ZJM low-rank coal sample was considerably higher than that of the SH high-rank coal *** imbibition process of the ZJM sample exhibited a high imbibition rate and high total-imbibition volume,whereas the SH sample exhibited a slow imbibition rate and low total-imbibition *** ZJM sample had a complex pore structure and diverse pore-size distribution with a lower mercury withdrawal efficiency at 59.60%,whereas the SH sample had a relatively uniform pore-size distribution with a higher mercury withdrawal efficiency at 97.62%.The response of adsorption and desorption of the ZJM sample to water was more significant than that of the SH *** desorption hysteresis of the ZJM sample was stronger than that of the SH sample and was more prominently affected by water,which was consistent with its strong wettability and complex pore-throat configuration.A comprehensive adsorption and desorption mode was constructed for high-and low-rank coal samples under coal–water–gas coupling *** research results are important to enrich the geological theory of high-and low-rank CBM and to guide efficient CBM recovery.

关键词： coalbed methane adsorption-desorption desorption hysteresis wettability pore structure coal-water-gas coupling