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Spatial Differences of Coastal Urban Expansion in China from 1970s to 2013

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Chinese Geographical Science 2015年第4期25卷 389-403页

作者： SHI Lifeng LIU Fang ZHANG Zengxiang ZHAO Xiaoli LIU Bin XU Jinyong WEN Qingke YI ling hu Shunguang Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences University of Chinese Academy of Sciences

As the ′economic engines′ of China,coastal cities have developed and expanded considerably since the 1970 *** this study,information on the urban expansion process of Chinese coastal cities from the 1970 s to 2013 was *** the analysis of stage characteristics,spatial expansion modes,influences on land use,centroid shifts,and spatial morphological evolutions,the spatial differences of coastal urban expansion were *** indicate that 1) the expansion stages of southern coastal cities are more complex than those of northern coastal cities,and the expansion ranges and speeds of the former are far higher than those of the latter;2) the spatial expansion of southern coastal cities mostly adopt a single mode,whereas northern coastal cities mostly adopt a mixed mode;3) significant spatial differences in the occupations of different land sources exist between the south and the north along the coastline;4) the centroid of coastal cities tends to migrate toward the coastline,and the centroid shift distances of southern coastal cities are clearly higher than those of northern coastal cities;and 5) the spatial morphology of southern coastal cities tends to be compact,whereas that of northern coastal cities tends to be *** have a powerful significance in terms of guiding urban expansion and its spatial differences in coastal *** expansion in coastal cities will encounter new opportunities and challenges under the guidance of new types of urbanization strategies.

关键词： urban expansion spatial difference coastal cities remote sensing China

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苏葶宣肺颗粒的制备工艺及初步药效研究

中南药学 2024年第3期22卷 612-618页

作者：叶晨雨周丽玲姜德兰卫张海英新疆医科大学第四临床医学院乌鲁木齐830000 新疆医科大学中医学院乌鲁木齐830000 新疆医科大学附属中医医院乌鲁木齐830000 新疆中药炮制研究重点实验室乌鲁木齐830000

目的优选苏葶宣肺颗粒的最佳提取工艺和成型工艺,并探讨其对气管平滑肌的作用。方法采用L9(34)正交设计实验法,以迷迭香酸和黄芩苷的含量以及浸膏得率为指标,考察提取次数、提取时间和加水倍量对苏葶宣肺颗粒提取工艺的影响,优选苏葶宣... 详细信息

目的优选苏葶宣肺颗粒的最佳提取工艺和成型工艺,并探讨其对气管平滑肌的作用。方法采用L9(34)正交设计实验法,以迷迭香酸和黄芩苷的含量以及浸膏得率为指标,考察提取次数、提取时间和加水倍量对苏葶宣肺颗粒提取工艺的影响,优选苏葶宣肺颗粒的最佳提取工艺。以制粒情况、成型率、吸湿率、休止角及溶解度为评价指标,对辅料种类和药辅比例等因素进行考察,确定最佳制剂成型工艺。制备大鼠离体气管环后浸泡于K-H液,采用BL-420S生物机能系统测定其张力变化,分别观察苏葶宣肺颗粒对大鼠正常离体气管和磷酸组胺(His)、乙酰胆碱(ACh)致痉的大鼠离体气管张力的影响,计算解痉率。结果苏葶宣肺颗粒的最佳提取工艺为:加10倍量水,浸泡30 min,提取2次,每次提取60 min。3批正交验证实验综合评分均数为92.07,RSD为0.51%。最佳成型工艺为:浸膏、糊精、淀粉按3∶2.5∶4的比例制成软材,用10目筛网制成颗粒。苏葶宣肺颗粒对大鼠正常离体气管平滑肌具有舒张作用,对ACh和His致大鼠离体气管平滑肌收缩均有一定的解痉作用。结论本文建立了苏葶宣肺颗粒稳定可行的制备工艺,为后续的研发、质量控制奠定了基础。苏葶宣肺颗粒对离体气管平滑肌有舒张作用,其机制可能与抗组胺和抑制胆碱受体有关。

关键词：苏葶宣肺颗粒迷迭香酸黄芩苷制备工艺正交实验药效研究

Mapping regional cropping patterns by using GF-1 WFV sensor data

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Journal of Integrative Agriculture 2017年第2期16卷 337-347页

作者： SONG Qian zhou Qing-bo WU Wen-bin hu Qiong LU Miao LIU Shu-bin Key Laboratory of Agri-informatics Ministry of Agriculture/Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Beijing 100081 P.R. China Remote Sensing Technology Center Heilongjiang Academy of Agricultural Sciences Harbin 150086 P.R.China

The successful launched Gaofen satellite no. 1 wide field-of-view （GF-1 WFV） camera is characterized by its high spatial resolution and may provide some potential for regional crop mapping. This study, taking the Bei＇an City, Northeast China as the study area, aims to investigate the potential of GF-1 WFV images for crop identification and explore how to fully use its spectral, textural and temporal information to improve classification accuracy. In doing so, an object-based and Random Forest （RF） algorithm was used for crop mapping. The results showed that classification based on an optimized single temporal GF-1 image can achieve an overall accuracy of about 83%, and the addition of textural features can im- prove the accuracy by 8.14%. Moreover, the multi-temporal GF-1 data can produce a classification map of crops with an overall accuracy of 93.08% and the introduction of textural variables into multi-temporal GF-1 data can only increase the accuracy by about 1%, which suggests the importance of temporal information of GF-1 for crop mapping in comparison with single temporal data. By comparing classification results of GF-1 data with different feature inputs, it is concluded that GF-1 WFV data in general can meet the mapping efficiency and accuracy requirements of regional crop. But given the unique spectral characteristics of the GF-1 WFV imagery, the use of textual and temporal information is needed to yield a satisfactory accuracy.

关键词： crop mapping GF-1 object-based Random Forest

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苍山维管植物多样性

大理大学学报 2024年第6期9卷 47-58页

作者：蒋显锋刘天猛陆佳周也富胡小康大理大学农学与生物科学学院云南大理671003 苍山洱海一体化保护与流域绿色发展云南省高校协同创新中心云南大理671003 苍山森林生态系统云南省野外科学观测研究站云南大理671003 大理大学生物科学馆云南大理671003

目的:系统调查整理苍山维管植物状况与珍稀濒危植物生存现状。方法:通过查阅历史文献和标本记录并结合样线法调查整理苍山维管植物名录,整理分析苍山珍稀濒危植物物种数量与种群规模,对被子植物进行区系分析。结果:大理苍山共记载野生... 详细信息

目的:系统调查整理苍山维管植物状况与珍稀濒危植物生存现状。方法:通过查阅历史文献和标本记录并结合样线法调查整理苍山维管植物名录,整理分析苍山珍稀濒危植物物种数量与种群规模,对被子植物进行区系分析。结果:大理苍山共记载野生维管植物208科996属3246种(含49亚种、227变种、2变型)。蕨类植物36科89属360种(含9变种),裸子植物8科14属20种(含4变种),被子植物164科893属2866种(含49亚种、214变种、2变型)。其中,国家重点保护野生植物62种,云南省重点保护野生植物6种,极小种群保护对象2种。结论:苍山具有较高的维管植物多样性,模式植物与保护植物十分丰富,但特有植物相对较少。

关键词：大理苍山维管植物珍稀濒危植物国家重点保护野生植物植物区系研究

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ERG3 and ERG11 genes are critical for the pathogenesis of Candida albicans during the oral mucosal infection

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International Journal of Oral Science 2018年第1期10卷 57-64页

作者： Yujie zhou Min Liao Chengguang Zhu Yao hu Ting Tong Xian Peng Mingyun Li Mingye Feng Lei Cheng Biao Ren Xuedong zhou State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology Sichuan University

The hyphal development of Candida albicans(***) has been considered as an essential virulent factor for host cell ***, the missing link between hyphae and virulence of *** is also been discovered. Here, we identified that the null mutants of ERG3 and ERG11, two key genes in ergosterol biosynthesis pathway, can form typical hyphae but failed to cause the oral mucosal infection in vitro and in vivo for the first time. In particular, the erg3Δ/Δ and erg11Δ/Δ strains co-cultured with epithelial cells significantly reduced the adhesion, damage, and cytokine(interleukin-1α(IL-1α)) production, whereas the invasion was not affected in vitro. Importantly, they were incapable of extensive hyphal invasion, formation of micro-abscesses, and tongue epithelium damage compared to wild type due to the decrease of the colonization and epithelial infection area in a murine oropharyngeal candidiasis model. The fluconazole(FLC), an antifungal targeted at ergosterol biosynthesis, relieved the epithelial infection of *** vitro and in vivo even under non-growth inhibitory dosage confirming the virulent contribution of ergosterol biosynthesis pathway. The erg3Δ/Δ and erg11Δ/Δ strains were cleared by macrophages similar to wild type, whereas their virulence factors including agglutinin-like sequence 1(Als1), secreted aspartyl proteinase 6(Sap6), and hyphal wall protein-1(Hwp1) were significantly reduced indicated that the non-toxicity might not result from the change on immune tolerance but the defective virulence. The incapacity of erg3Δ/Δ and erg11Δ/Δ in epithelial infection highlights the contribution of ergosterol biosynthesis pathway to *** pathogenesis and fluconazole can not only eliminate the fungal pathogens but also reduced their virulence even at low dosage.

关键词： ANTIFUNGAL AGENTS MOUSE MODEL RESISTANCE FLUCONAZOLE MECHANISMS EXPRESSION PROTEINASES PATHWAY YEAST

Quantifying quantum correlation via quantum coherence

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Frontiers of physics 2018年第4期13卷 285-290页

作者： Guang-Yong zhou Lin-Jian huang Jun-Ya Pan Li-Yun hu Jie-hui huang College of Physics and Communication Electronics Jiangxi Normal University Nanchang 330022 China

Resource theory is applied to quantify the quantum correlation of a bipartite state and a computable measure is proposed. Since this measure is based on quantum coherence, we present another possible physical meaning for quantum correlation, i.e., the minimum quantum coherence achieved under local unitary transformations. This measure satisfies the basic requirements for quantifying quantum cor- relation and coincides with concurrence for pure states. Since no optimization is involved in the final definition, this measure is easy to compute irrespective of the Hilbert space dimension of the bipartite state.

关键词： resource theory quantum correlation quantum coherence

急性脑梗死合并脑白质疏松症患者血清CP、MBP、MCP-1与病情严重程度和预后的关系

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现代生物医学进展 2024年第2期24卷 353-357,318页

作者：杜娟周晓雨张淼张雪玲蓝文雅南京鼓楼医院集团宿迁医院神经内科江苏宿迁223800 南京医科大学附属脑科医院脑血管病救治中心江苏南京210000

目的:探究急性脑梗死(ACI)合并脑白质疏松症(LA)患者血清C肽(CP)、髓鞘碱性蛋白(MBP)、单核细胞趋化蛋白-1(MCP-1)水平与病情严重程度和预后关系。方法:选取南京鼓楼医院集团宿迁医院于2021年3月至2023年3月期间收治的ACI合并LA患者117... 详细信息

目的:探究急性脑梗死(ACI)合并脑白质疏松症(LA)患者血清C肽(CP)、髓鞘碱性蛋白(MBP)、单核细胞趋化蛋白-1(MCP-1)水平与病情严重程度和预后关系。方法:选取南京鼓楼医院集团宿迁医院于2021年3月至2023年3月期间收治的ACI合并LA患者117例作为观察组,根据根据LA严重程度分为重度组39例、中度组40例和轻度组38例。另选取同期体检健康人120例纳入对照组。检测血清CP、MBP、MCP-1水平。对ACI合并LA患者行6个月的随访。多因素Logistic回归分析ACI合并LA患者预后不良的影响因素。受试者特征曲线(ROC)分析血清CP、MBP和MCP-1对ACI合并LA患者预后的预测价值。结果:与对照组相比,观察组MBP、MCP-1更高,CP更低(P<0.05)。重度组血清CP显著低于轻度组和中度组,MBP、MCP-1水平显著高于轻度组和中度组;中度组血清CP显著低于轻度组,MBP、MCP-1水平显著高于轻度组(均P<0.05)。与预后良好组相比,预后不良组CP更低,MBP、MCP-1更高(P<0.05)。多因素Logistic回归分析显示NIHSS评分升高、MBP升高、MCP-1升高是ACI合并LA患者预后不良的独立危险因素,CP升高是保护因素(P<0.05)。ROC分析结果显示CP、MBP和MCP-1联合预测ACI合并LA患者预后不良的曲线下面积(AUC)为0.916,高于CP、MBP和MCP-1单独预测。结论:ACI合并LA患者血清CP较健康群体更低,血清MBP、MCP-1水平较健康群体更高,且CP、MBP和MCP-1与患者病情程度存在密切联系。血清CP、MBP和MCP-1联合检测对ACI合并LA患者预后有较高预测价值。

关键词：急性脑梗死脑白质疏松症 CP MBP MCP-1 病情严重程度预后

A prototype web-based analysis platform for drought monitoring and early warning

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International Journal of Digital Earth 2020年第7期13卷 817-831页

作者： Mattijn van Hoek Jie zhou Li Jia Jing Lu Chaolei Zheng Guangcheng hu Massimo Menenti State Key Laboratory of Remote Sensing Science Chinese Academy of SciencesInstitute of Remote Sensing and Digital EarthBeijingPeople’s Republic of China HKV Consultants LelystadThe Netherlands Key Laboratory for Geographical Process Analysis&Simulation of hubei Province/College of Urban and Environmental SciencesCentral China Normal UniversityWuhanPeople’s Republic of China

It has long been recognized that an effective drought monitoring and early warning system,which provides functions for real-time condition monitoring and prediction,risk assessment,information dissemination and response recommendation,is very important for the preparedness for and mitigation of drought *** this article,we review the currently existing drought monitor and early warning systems,discuss applicable remote sensing datasets and drought indicators and present the development of a web-based quasi-real-time Global Drought Monitoring&Analysis Platform(Web-GDMAP).The Web-GDMAP is built upon a series of indicators derived from multi-source satellite remote sensing data and various other sources of *** a technical perspective,the Web-GDMAP system includes a series of components from data storage,model implementation and distribution,to client-side visualization and user intuitive *** a theoretical perspective,the Web-GDMAP system integrates multi-indicators on different aspects of drought,including anomalies in precipitation,anomalies in land surface thermal and vegetation conditions,water deficit of soil and plants,*** case studies on applying the developed Web-GDMAP in the Asian region are *** improvements and perspectives are discussed.

关键词： Drought monitoring remote sensing web-based Open Geospatial Consortium(OGC) time series

Breeding High-Grain Quality and Blast Resistant Rice Variety Using Combination of Traditional Breeding and Marker-Assisted Selection

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Rice science 2021年第5期28卷 422-426,I0004-I0009页

作者： zhou Zheng Sun Liang hu Wenbin zhou Bin TAo Shuhua Zhang Shihui LU Yanmei Zhao Zhenghong Chen Caiyan Key Laboratory of Agro-Ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China Key Laboratory of indica Rice Genetics and Breeding in the Middle and Lower Reaches of Yangtze River Valley Ministry of Agriculture and Rural AffairsHunan Rice Research InstituteHunan Academy of Agricultural SciencesChangsha 410125China University of Chinese Academy of Science Beijing 100049China

We reported a novel rice variety developed by integrating the advantages of high eating quality from Xiangwanxiaa 17(XWX17)and rice blast resistance from Gumei 4(GM4)using a combination of traditional breeding and marker-assisted selection(MAS).Using molecular markers for QTLs/genes responsible for amylose content(AC),fragrance and blast resistance,three inbred lines were selected.

关键词： breeding Breeding integrating