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Communications in Theoretical Physics 2022年第7期74卷 146-153页

作者： Wei-Jie Zhang Yi-Piao Wu ling-zhi tang Guo-Qing Zhang Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials School of Physics and Telecommunication EngineeringSouth China Normal UniversityGuangzhou 510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter Frontier Research Institute for PhysicsSouth China Normal UniversityGuangzhou 510006China

Disorders and long-range hoppings can induce exotic phenomena in condensed matter and artificial *** study the topological and dynamical properties of the quasiperiodic SuSchrier-Heeger model with long-range *** is found that the interplay of quasiperiodic disorder and long-range hopping can induce topological Anderson insulator phases with nonzero winding numbers ω=1,2,and the phase boundaries can be consistently revealed by the divergence of zero-energy mode localization *** also investigate the nonequilibrium dynamics by ramping the long-range hopping along two different *** critical exponents extracted from the dynamical behavior agree with the Kibble-Zurek mechanic prediction for the path with W=*** particular,the dynamical exponent of the path crossing the multicritical point is numerical obtained as 1/6~0.167,which agrees with the unconventional finding in the previously studied XY spin ***,we discuss the anomalous and non-universal scaling of the defect density dynamics of topological edge states in this disordered system under open boundary condictions.

关键词： topological Anderson insulator higher winding number Kibble-Zurek machanic

Non-Hermitian topological Anderson insulators

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Science China(Physics,Mechanics & Astronomy) 2020年第6期63卷 2-12页

作者： Dan-Wei Zhang ling-zhi tang Li-Jun Lang Hui Yan Shi-Liang Zhu Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials GPETR Center for Quantum Precision Measurement and SPTESouth China Normal UniversityGuangzhou 510006China National Laboratory of Solid State Microstructures School of PhysicsNanjing UniversityNanjing 210093China

Non-Hermitian systems can exhibit exotic topological and localization *** we elucidate the non-Hermitian effects on disordered topological systems using a nonreciprocal disordered Su-Schrieffer-Heeger *** show that the non-Hermiticity can enhance the topological phase against disorders by increasing bulk ***,we uncover a topological phase which emerges under both moderate non-Hermiticity and disorders,and is characterized by localized insulating bulk states with a disorder-averaged winding number and zero-energy edge *** topological phases induced by the combination of non-Hermiticity and disorders are dubbed non-Hermitian topological Anderson *** reveal that the system has unique non-monotonous localization behavior and the topological transition is accompanied by an Anderson *** properties are general in other non-Hermitian models.

关键词： topological insulators non-Hermitian systems localization properties

Ferromagnetism in High-Surface-Area ZnO Nanosheets Prepared by a Template-Assisted Hydrothermal Method

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Chinese Physics Letters 2018年第6期35卷 90-93页

作者： Hui-Fang Yang ling-zhi tang Qiang Sun Lei Sun Zhen-Hua Li Shu-Xia Ren School of Material Science and Engineering Shijiazhuang TieDao University

High-surface-area ZnO nanosheets are prepared using a template-assisted hydrothermal method.A saturation moment as high as 0.02 emu/g is obtained for the ZnO *** photoluminescence spectroscopy and x-ray photoelectron spectroscopy demonstrate the existence of abundant oxygen vacancies on the surfaces of the *** addition,the oxygen vacancy concentration increases with an increasing nanosheet surface *** results show that the origin of the room-temperature ferromagnetism is closely related with a large surface area and oxygen vacancies of the *** finding suggests that the high-surface-area ZnO nanosheets are promising to be applied to spintronic devices.

关键词： ZnO Ferromagnetism in High-Surface-Area ZnO Nanosheets Prepared by a Template-Assisted Hydrothermal Method

Induced pluripotent stem cell-related approaches to generate dopaminergic neurons for Parkinson's disease

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Neural Regeneration Research 2025年第11期20卷 3193-3206页

作者： ling-Xiao Yi Hui Ren Woon Genevieve Saw Li Zeng Eng King Tan zhi Dong Zhou National Neuroscience Institute Singapore Nanyang Technology University Singapore Department of Neurology Singapore General HospitalSingapore Signature Research Program in Neuroscience and Behavioral Disorders Duke-NUS Medical SchoolSingapore

The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative *** the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and *** induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease *** current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem *** benefits of induced pluripotent stem cell-based research are *** dopaminergic neuron differentiation protocols from induced pluripotent stem cells are *** emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are ***,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.

关键词： dopaminergic neurons induced pluripotent stem cells Parkinson's disease stem cell approaches

Social function scores and influencing factors in patients with residual depressive symptoms

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World Journal of Psychiatry 2025年第1期15卷 117-127页

作者： Zong-ling Liao Xiao-Li Pu zhi-Yi Zheng Jie Luo Department 1 of Psychiatry Gele Mountain Hospital of Chongqing Mental Health CenterChongqing 400030China Department of Psychology Chongqing Jiangjin District Psychiatric HospitalChongqing 402260China Department of Psychiatry Chongqing Third Social Welfare InstituteChongqing 400036China Women and Children’s Mental Health Center Affiliated Hospital of Chongqing Population and Family Planning Research InstituteChongqing 400020China

BACKGROUND At present,the influencing factors of social function in patients with residual depressive symptoms are still *** depressive symptoms are highly harmful,leading to low mood in patients,affecting work and interpersonal communication,increasing the risk of recurrence,and adding to the burden on *** the influencing factors of their social function is of great *** To explore the social function score and its influencing factors in patients with residual depressive *** This observational study surveyed patients with residual depressive symptoms(case group)and healthy patients undergoing physical examinations(control group).Participants were admitted between January 2022 and December *** functioning was assessed using the Sheehan Disability Scale(SDS),and scores were compared between *** influencing SDS scores in patients with residual depressive symptoms were analyzed by applying multiple linear regression while using the receiver operating characteristic curve,and these RESULTS The SDS scores of the 158 patients with depressive symptoms were 11.48±*** with the control group,the SDS scores and all items in the case group were *** scores were higher in patients with relapse,discon-tinuous medication,drug therapy alone,severe somatic symptoms,obvious residual symptoms,and anxiety scores≥*** history,medication compliance,therapy method,and residual symptoms correlated positively with SDS scores(r=0.354,0.414,0.602,and 0.456,respectively).Independent influencing factors included disease history,medication compliance,therapy method,somatic symptoms,residual symptoms,and anxiety scores(P<0.05).The areas under the curve for predicting social functional impairment using these factors were 0.713,0.559,0.684,0.729,0.668,and 0.628,respectively,with sensitivities of 79.2%,61.8%,76.8%,81.7%,63.6%,and 65.5%and specificities of 83.3%,87.5%,82.6%,83.3%,86.7%,and 92.1%,respectively.C

关键词： Depressive Residual symptoms Social function Influence factors

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： zhi-Jian tang Yuan-Ming Pan Wei Li Rui-Qiong Ma Jian-Liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

A robust and unique approach for tuning the energy level of Ag_(2)Se quantum dots via“on-surface”manipulation of nitrogencontaining groups of surface-coordinated ligands

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Nano Research 2023年第11期16卷 12608-12617页

作者： Meng-Yao Luo Bo tang An-An Liu Jing-Ya Zhao zhi-ling Zhang Dai-Wen Pang The Institute for Advanced Studies and College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Biosensing and Molecular RecognitionFrontiers Science Center for New Organic MatterResearch Center for Analytical SciencesCollege of ChemistryFrontiers Science Center for Cell ResponsesNankai UniversityTianjin 300071China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

Effects of surface chemistry on energy levels or optical properties of semiconductor nanocrystals have attracted considerable attention and show great promise in broad ***,it remains challenging to controllably tune the photoluminescence(PL)of quantum dots(QDs)by manipulating surface ***,we investigated effects of the ligand,glutathione(GSH),on PL properties of near-infrared(NIR)Ag_(2)Se QDs by“on-surface”manipulation,that is,precisely manipulating the chelating group without dissociating the ligand from the *** anchoring of the amino group was found to be controlled by solution pH,whereas the binding of the thiol group to the Ag+was pH independent,maintaining the“on-surface”state of *** tuning the pH-controlled binding of amino groups,the energy level or the bandgap of Ag2Se QDs could be increased by up to 140 *** increased bandgap resulted in the blueshift of PL spectrum,which could be reversibly tuned by up to 75 *** pH-mediated tunable PL properties of QDs could also be extended to other nitrogen-containing pH-sensitive groups which could coordinate to the Ag+,not limited to the amino *** work would facilitate the study of nanocrystal surface chemistry and our model that the binding of amino groups affected energy levels of Ag2Se QDs might facilitate new insights into the electronic structure and energy level of other QD-ligand complexes.

关键词： quantum dot(QD) surface chemistry ligand energy level pH

Simulation of Voltage SET Operation in Phase-Change Random Access Memories with Heater Addition and Ring-Type Contactor for Low-Power Consumption by Finite Element Modeling

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Chinese Physics Letters 2010年第6期27卷 250-253页

作者： GONG Yue-Feng SONG zhi-tang ling Yun LIU Yan LI Yi-Jin State Key Laboratory of Functional Materials for Informatics Laboratory of Nanotechnology Shanghai Institute of Micro-system and Information Technology Chinese Academy of Sciences Shanghai 200050

A three-dimensional finite element model for phase change random access memory is established to simulate electric, thermal and phase state distribution during （SET） operation. The model is applied to simulate the SET behaviors of the heater addition structure （HS） and the ring-type contact in the bottom electrode （RIB） structure. The simulation results indicate that the small bottom electrode contactor （BEC） is beneficial for heat efficiency and reliability in the HS cell, and the bottom electrode contactor with size Fx=80 nm is a good choice for the RIB cell. Also shown is that the appropriate SET pulse time is lOOns for the low power consumption and fast operation.

关键词： Simulation Models Cells Chops Electrodes Sets Lymphocytes

Development of glyphosate-tolerant transgenic cotton plants harboring the G2-aroA gene

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Journal of Integrative Agriculture 2017年第3期16卷 551-558页

作者： ZHANG Xiao-bing tang Qiao-ling WANG Xu-jing WANG zhi-xing Biotechnology Research Institute Chinese Academy of Agricultural Sciences Biology Institute Hebei Academy of Sciences

Given that glyphosate weed control is an effective strategy to reduce costs and improve economic outcomes of agricultural production in China,the development of glyphosate-resistant cotton holds great *** an Agrobacterium-mediated transformation method,a new G2-aroA gene that encodes 5-enolpyruvylshikimate-3-phosphate synthase（EPSPS）was transformed into cotton cultivar *** transgenic cotton plants were regenerated from a callus tissue culture via kanamycin *** regenerated cotton plants were obtained and allowed to flower normally to produce *** results from polymerase chain reaction（PCR）and Southern and Western blot analyses indicated that the target gene was integrated into the cotton chromosome and was expressed effectively at the protein *** glyphosate tolerance analysis showed that the transgenic cotton had a high resistance to ***,even cotton treated with 45.0 mmol L^–1 of glyphosate was able to slowly grow,bloom and *** transgenic cotton may be used for cotton breeding research of glyphosate-tolerant cotton.

关键词： cotton (Gossypium hirsutum L.) Agrobacterium-mediated method glyphosate G2-aroA genetic transformation

Existence and Instability of Some Nontrivial Positive Steady States for the SKT Model with Double Cross Diffusion

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Acta Mathematicae Applicatae Sinica 2023年第3期39卷 623-637页

作者： zhi-bao tang School of Mathematical Sciences Capital Normal UniversityBeijing 100048China

This paper is concerned with the nonconstant positive steady states of the Shigesada-Kawasaki-Teramoto model for two competing species with double cross-diffusion *** applying the Lyapunov-Schmidt decomposition method,the higher order expansion and some detailed spectral analysis,we prove the existence,asymptotic behavior and spectral instability of non-trivial steady states in high-dimensional case when one of the two cross-diffusion coefficients is large enough.

关键词： double cross-diffusion existence asymptotic behavior spectral instability