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Effect of scar-producing moxibustion at the acupoints Zusanli(ST 36) and Feishu(BL 13) on neutrophil-to-lymphocyte ratio and quality of life in patients with non-small-cell lung cancer: A randomized,controlled trial

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Journal of Traditional Chinese Medicine 2018年第3期38卷 439-446页

作者： Zhang Mengxue guan ling Wang Lili Li Ying Department of Acupuncture and Moxibustion Chinese People's Liberation Army General Hospital

OBJECTIVE: To evaluate the effect of heat stimulation via scar-producing moxibustion at the acupoints Zusanli(ST 36) and Feishu(BL 13) on the neutrophil-to-lymphocyte ratio(NLR) and quality of life in patients with non-small-cell lung cancer(NSCLC).METHODS: Seventy patients with NSCLC were randomly assigned into two groups: group A received scar-producing moxibustion at the acupoints Zusanli(ST 36) and Feishu(BL 13) every day for 6 weeks, while group B received no intervention(control group). Outcome measures were the NLR and the scores from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire(EORTC QLQ-C30). The NLR and the EORTC QLQ-C30 were assessed at baseline and at the end of 6 ***: Five participants dropped out, leaving afinal total of 65 participants who completed the trial. Groups A and B had a similar mean NLR at baseline. After the treatment course, the NLR in group A was significantly lower than that in group B(P <0.001). Compared with group B, the EORTC QLQ-C30 scores in group A were significantly greater in terms of global health status or quality of life(P < 0.001) and function(P < 0.05), and significantly lower in terms of symptoms(P < 0.05).CONCLUSION: The present study suggests that performing scar-producing moxibustion by heat-stimulating the acupoints Zusanli(ST 36) and Feishu(BL13) effectively decreases the NLR and improves the quality of life in patients with NSCLC.

关键词： Carcinoma non-small-cell lung Scar-ring moxibustion Point ST36 (Zusanli) Point BL13(Feishu) Immunity Neutrophils Lymphocytes Quality of life Randomized controlled trial

Infrared thermography and meridian-effect evidence and explanation in Bell's palsy patients treated by moxibustion at the Hegu (LI4) acupoint Overall regulation or a specific target?

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Neural Regeneration Research 2012年第9期7卷 680-685页

作者： ling guan Gaobo Li Yiling Yang Xiufang Deng Peisi Cai Department of Acupuncture and Moxibustion Chinese PLA General Hospital Beijing 100853 China Beijing Aierci Infrared Medical Science and Technology Limited Company Beijing 100055 China

Subjects with Bell＇s palsy and healthy individuals were treated with moxibustion thermal stimulation on the Hegu （LI4） acupoint; an infrared thermal imaging system was used to observe facial-temperature changes. Bell＇s palsy patients developed low or high temperatures at the affected side, with poor symmetry. Healthy people showed high temperatures on the forehead, medial angle of the eye, nasal ala and around the lips, but low temperatures on bilateral cheeks, thus forming a ＂T-type hot area＂ in the face, with good temperature symmetry. Moxibustion treatment for 11 minutes significantly improved high asymmetry in temperature in the faces of Bell＇s palsy patients. This evidence indicates that moxibustion treatment on Hegu enables increases in facial temperatures in healthy people and Bell＇s palsy patients, especially around the lips. Moxibustion stimulation at the Hegu not only improves the global circulation but also has specific effects on the lips in Bell＇s palsy patients, but the underlying mechanism needs further investigation.

关键词： Bell’s palsy infrared skin temperature face moxibustion neural regeneration

Formation and structure of composite coating of HDA and micro-plasma oxidation on A3 steel

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中国有色金属学会会刊：英文版 2004年第Z1期14卷 310-314页

作者： YU Sheng-xue XIA Yuan CHEN ling guan Yong-jun YAO Mei Department of Environment Science and Chemical Engineering Yanshan University Qinhuangdao 066004 China Institute of Mechanics Chinese Academy of Science Beijing 100080 China Institute of Mechanics Chinese Academy of Science Beijing 100080 China Department of Environment Science and Chemical EngineeringYanshan University Qinhuangdao 066004 China Institute of Mechanics Chinese Academy of Science Beijing 100080 China College of Materials Science and EngineeringYanshan University Qinhuangdao 066004 China

Composite coatings were obtained on A3 steel by hot dipping aluminum(HDA) at 720 ℃ for 6 min and micro-plasma oxidation(MPO) in alkali electrolyte. The surface morphology, element distribution and interface structure of composite coatings were studied by means of XRD, SEM and EDS. The results show that the composite coatings obtained through HDA/MPO on A3 steel consist of four layers. From the surface to the substrate, the layer is loose Al2O3 ceramic, compact Al2O3 ceramic, Al and FeAl intermetallic compound layer in turn. The adhesions among all the layers are strengthened because the ceramic layer formed at the Al surface originally, FeAl intermetallic compound layer and substrate are combined in metallurgical form through mutual diffusion during HDA *** experiment results disclose that the anti-corrosion performance and wear resistance of composite coating are obviously improved through HDA/MPO treatment.

关键词： hot dipping aluminum micro-plasma oxidation composite coating ceramic coating

Auxin regulation and MdPIN expression during adventitious root initiation in apple cuttings

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Horticulture Research 2020年第1期7卷 955-966页

作者： ling guan Yingjun Li Kaihui Huang Zong-Ming(Max)Cheng College of Horticulture Nanjing Agricultural University210095 NanjingChina Institute of Pomology Jiangsu Academy of Agricultural SciencesJiangsu Key Laboratory for Horticultural Crop Genetic Improvement210014 NanjingChina Department of Plant Sciences University of TennesseeKnoxvilleTN 37831USA

Adventitious root(AR)formation is critical for the efficient propagation of elite horticultural and forestry *** decades of research,the cellular processes and molecular mechanisms underlying AR induction in woody plants remain *** examined the details of AR formation in apple(Malus domestica)M.9 rootstock,the most widely used dwarf rootstock for intensive production,and investigated the role of polar auxin transport in postembryonic *** formation begins with a series of founder cell divisions and elongation of the interfascicular cambium adjacent to vascular *** process is associated with a relatively high indole acetic acid(IAA)content and hydrolysis of starch *** auxin treatment promoted this cell division,as well as the proliferation and reorganization of the endoplasmic reticulum and Golgi *** contrast,treatment with the auxin transport inhibitor N-1-naphthylphthalamic acid(NPA)inhibited cell division in the basal region of the cuttings and resulted in abnormal cell divisions during the early stage of AR *** addition,PIN-FORMED(PIN)transcripts were differentially expressed throughout the whole AR development *** also detected upregulation of MdPIN8 and MdPIN10 during induction;upregulation of MdPIN4,MdPIN5,and MdPIN8 during extension;and upregulation of all MdPINs during AR *** research provides an improved understanding of the cellular and molecular underpinnings of the AR process in woody plants.

关键词： hydrolysis elite dwarf

Characteristic Mode Analysis for Thin Dielectric Sheets with Alternative Surface Integral Equation

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Chinese Journal of Electronics 2022年第6期31卷 1181-1188页

作者： JIA Chunlai HE Zi DING Dazhi guan ling AI Xia LIU Jiaqi CHEN Xuewen Department of Communication Engineering Nanjing University of Science and Technology Science and Technology on Electromagnetic Scattering Laboratory Beijing Institute of Environmental Features National Key Laboratory of Science and Technology on Test Physics and Numerical Mathematics School of Physics and Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology

When the dielectric sheet is electrically thin in the normal direction, the conventional volume integral equation(VIE) can be approximately simplified to the surface one. On this basis, a novel surface integral equation-based formulation is presented for analyzing characteristic mode(CM) of thin dielectric sheets. The resultant CMs are expressed with tangential and normal components of electric volume currents, which are more intuitive than the conventional VIE-based one. Due to the application of volume equivalence principle, the proposed formulation is immune to non-physical modes. The CMs of typical thin dielectric bodies, including the dielectric substrate and radome, are analyzed to show that the proposed formulation is computationally efficient with encouraging accuracy.

关键词： normal components alternative surface integral equation thin dielectric sheets normal direction electric volume currents dielectric sheet radome radomes dielectric bodies surface integral equation-based formulation volume equivalence principle thin dielectric bodies tangential components nonphysical modes electromagnetic wave scattering conventional volume integral equation integral equations characteristic mode analysis dielectric substrate

Analysis and simulation of the tune ripple effect on beam spill ripple in RF-KO slow extraction

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Nuclear Science and Techniques 2022年第5期33卷 91-101页

作者： Wen-Bo Ye Hong-Juan Yao Shu-Xin Zheng Xia-ling guan Xue-Wu Wang Key Laboratory of Particle and Radiation Imaging(Tsinghua University) Ministry of EducationBeijing 100084China Laboratory for Advanced Radiation Sources and Application Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China

Tune ripple has a significant influence on beam spill ripple in RF-knockout(RF-KO)slow *** this study,a model was proposed to explain how the tune ripple affects the beam spill in RF-KO slow extraction;consequently,a simulation was performed using the lattice of the Xi’an Proton Application Facility(XiPAF)synchrotron to verify the *** simulation demonstrates that the tune ripple influences the beam spill in two *** the one hand,the tune ripple causes a direct fluctuation in the separatrix area,which induces beam spill *** the other hand,the tune ripple influences the emittance growth rate in RF-knockout slow *** two aspects simultaneously contribute to the beam spill ripple.

关键词： RF-knockout slow extraction Synchrotron Tune ripple Power supply ripple Beam spillripple

Differences in thermal effects of moxibustion at Zusanli(ST 36) and Hegu(LI 4) on various facial areas in healthy people

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Journal of Traditional Chinese Medicine 2012年第3期32卷 397-403页

作者： Yiling Yang Laixi Ji Gaobo Li Xiufang Deng Peisi Cai ling guan Department of Acupunc-ture and Moxibustion General Hospital of Chinese PLABeijing 100853China Shanxi University of Traditional Chinese Medicine Taiyuan 030024China Beijing Aierci Infrared Medical Science and Technology Limited Company Beijing 100853China

OBJECTIVE:To study the effects of temperature on different facial areas by suspended moxibustion at two points,Zusanli(ST 36) and Hegu(LI 4),and probe the phenomena underlying self-regulation in the human body after thermal ***:Thirty healthy volunteers accepted moxibustion over Zusanli(ST 36) and Hegu(LI 4),and the order of moxibustion points was randomly *** method:suspension of moxibustion over Zusanli(ST 36) and Hegu(LI 4) on both sides was performed using an ignited moxa stick stuck in a support for 20 *** method:An infrared thermal image of the face was taken before and after suspended moxibustion using a CK350 medical infrared thermal imaging *** analysis:A thermal microscopic section view system(TMTSys) was used to analyze the change in temperature in special facial *** analysis was carried out using SPSS 14.0 ***:Before moxibustion was suspended,the facial thermal image showed a T-shaped thermal area related to the vascular distribution with even temperature and good symmetry on both *** moxibustion over Zusanli(ST 36) have a very significant increase in temperature at the forehead,around the nose,at the corners of the mouth,and at the cheeks and lips(P<0.01).Suspended moxibustion over Hegu(LI 4) also have a significant(P<0.05) increase in temperature around the nose,the corners of the mouth,the cheeks,and lips,where has a new high temperature area was formed(P<0.01).Suspended moxibustion over Hegu(LI 4) raised the temperature at the middle point of the lips more obviously than did Zusanli(ST 36) in the same person,(P<0.05).After 10 min of moxibustion over Zusanli(ST 36) and Hegu(LI 4),the change in temperature in the facial area reached its peak ***:Facial infrared thermography of healthy people revealed a T-shaped thermal area reflecting a physiological thermal *** over Zusanli(ST 36) or Hegu(LI 4) raised the temperature in this fac

关键词： Moxibustion Point ST 36(Zusanli) Point LI 4(Hegu) Infrared thermal image

Acupuncture and vitamin B_(12) injection for Bell's palsy:no high-quality evidence exists

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Neural Regeneration Research 2015年第5期10卷 808-813页

作者： Li-li Wang ling guan Peng-liang Hao Jin-long Du Meng-xue Zhang Department of Acupuncture and Moxibustion Chinese PLA General Hospital

OBJECTIVE： To assess the efficacy of acupuncture combined with vitamin B12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell＇s palsy. DATA RETRIEVAL： A computer-based online retrieval of Medline, Web of Science, CNKI, CBM databases until April 2014 was performed for relevant trials, using the key words ＂Bell＇s palsy or idiopathic facial palsy or facial palsy＂ and＂acupuncture or vitamin B12 or methylcobalamin＂. STUDY SELECTION： All randomized controlled trials that compared acupuncture with acupuncture combined with vitamin B12 in patients with Bell＇s palsy were included in the me- ta-analysis. The initial treatment lasted for at least 4 weeks. The outcomes of incomplete facial recovery were monitored. The scoring index varied and the definition of healing was consistent. The combined effect size was calculated by using relative risk （RR） with 95% confidence interval （C/） using the fixed effect model of Review Manager. MAIN OUTCOME MEASURES： Incomplete recovery rates were chosen as the primary outcome. RESULTS： Five studies involving 344 patients were included in the final analysis. Results showed that the incomplete recovery rate of Bell＇s palsy patients was 44.50% in the acupuncture combined with vitamin B12 group but 62.57% in the acupuncture alone group. The major acupoints were Taiyang （EX-HN5）, Jiache （ST6）, Dicang （ST4） and Sibai （ST2）. The combined effect size showed that acupuncture combined with vitamin B12 was better than acupuncture alone for the treatment of Belrs palsy （RR = 0.71, 95%CI： 0.58-0.87; P = 0.001）, this result held true when 8 patients lost to follow up in one study were included into the analyses （RR = 0.70, 95%CI： 0.58-0.86; P = 0.0005）. In the subgroup analyses, the therapeutic effect in patients of the electroacupuncture subgroup was better than in the non-electroacupuncture subgroup （P = 0.024）. There was no significant dif- ference in the incomplete recovery rate by subgroup analysis on dru

关键词： nerve regeneration brain injury facial palsy Bell's palsy comparison methodologicalquality therapy fixed effect model acupuncture incomplete recovery randomized controlled trials electroacupuncture NSFC grants neural regeneration

Impacts of high temperature,relative air humidity,and vapor pressure deficit on the seed set of contrasting maize genotypes during flowering

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Journal of Integrative Agriculture 2024年第9期23卷 2955-2969页

作者： Xin Dong Baole Li Zhenzhen Yan ling guan Shoubing Huang Shujun Li Zhiyun Qi ling Tang Honglin Tian Zhongjun Fu Hua Yang Chongqing Academy of Agricultural Sciences Chongqing 401329China College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193China

Heat stress is a major constraint to current and future maize production at the global *** and female reproductive organs both play major roles in increasing seed set under heat stress at flowering,but their relative contributions to seed set are *** this study,a 2-year field experiment including three sowing dates in each year and 20 inbred lines was *** set,kernel number per ear,and grain yield were all reduced by more than 80%in the third sowing dates compared to the first sowing *** viability,silk emergence ratio,and anthesis-silking interval were the key determinants of seed set under heat stress;and their correlation coefficients were 0.89^(***),0.65^(***),and-0.72^(***),*** pressure deficit(VPD)and relative air humidity(RH)both had significant correlations with pollen viability and the silk emergence *** RH can alleviate the impacts of heat on maize seed set by maintaining high pollen viability and a high silk emergence *** a warming climate from 2020 to 2050,VPD will decrease due to the increased *** on their pollen viability and silk emergence ratios,the 20 genotypes fell into four different *** group with high pollen viability and a high silk emergence ratio performed better under heat stress,and their performance can be further improved by combining the improved flowering pattern traits.

关键词： maize pollen viability silk emergence heat stress relative humidity