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Value of Intrauterine Autologous Platelet-Rich Plasma Therapy on Endometrial Receptivity:A Literature Review

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Current Medical Science 2023年第6期43卷 1075-1083页

作者： Chu-jun LI Ya-dou ZHAN Xian-li ZHOU Jie YANG ling deng Xue-lan LI Xin CHEN Reproductive Medicine Center Shunde Hospital of Southern Medical University(The First People’s Hospital of Shunde)Shunde528300China

Endometrial receptivity is an important factor that influences embryo implantation.Thus,it is important to identify an applicable approach to improve endometrial receptivity in women undergoing assisted reproductive technology.Recently,growing evidence has indicated that intrauterine platelet-rich plasma(PRP)infusion is an effective method to obtain a satisfactory reproductive outcome by increasing endometrial thickness and improving endometrial receptivity.Therefore,the present review aims to outline the possible mechanisms of PRP on endometrial receptivity and summarize the present literature on the effects of PRP therapy in improving endometrial receptivity.

关键词： platelet-rich plasma intrauterine perfusion endometrial thickness endometrial receptivity

光敏色素A调控光响应基因表达及其翻译后修饰研究进展

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热带亚热带植物学报 2024年第1期32卷 143-150页

作者：邓玲刘勋成中国科学院华南植物园广州510650 华南国家植物园广州510650 中国科学院大学北京100049

光是调节植物生长发育最重要的环境信号因子之一。植物通过光受体感受自然环境中光的强度、方向以及光周期等信号的变化,从而调控其生长发育过程。光敏色素A(phytochrome A,PHYA)是植物中唯一的远红光受体蛋白,具有在黑暗下在细胞质中合... 详细信息

光是调节植物生长发育最重要的环境信号因子之一。植物通过光受体感受自然环境中光的强度、方向以及光周期等信号的变化,从而调控其生长发育过程。光敏色素A(phytochrome A,PHYA)是植物中唯一的远红光受体蛋白,具有在黑暗下在细胞质中合成,而在照光后快速入核和降解的特性,并通过多种途径精确调节了植物光响应基因的转录网络。同时,蛋白质翻译后修饰在调节PHYA稳定性和活性的过程中发挥了重要的作用。该文论述了PHYA调节光响应基因表达以及PHYA翻译后修饰方向的研究进展,并展望了PHYA在农作物分子设计育种中的应用前景。

关键词：光敏色素光受体光信号转导翻译后修饰

A Second Dose of GnRHa in Combination with Luteal GnRH Antagonist May Eliminate Ovarian Hyperstimulation Syndrome in Women with≥30 Follicles Measuring≥11 mm in Diameter on Trigger Day and/or Pre-trigger Peak Estradiol Exceeding 10 000 pg/mL

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Current Medical Science 2019年第2期39卷 278-284页

作者： ling deng Xue-Ian LI De-sheng YE Christophe Blockeel Xing-yu ZHOU Shi-ling CHEN Xin CHEN Center for Reproductive Medicine Department of Gynecology and ObstetricsNanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Reproductive Medicine Jiangmen Central HospitalJiangmen 529030China Centre for Reproductive Medicine Universitair Ziekenhuis Brussel(UZ Brussel)Laarbeeklaan 101-1090 BrusselsBelgium

This observational study included 21 patients at remarkably high risk of ovarian hyperstimulation syndrome(OHSS),characterized by more than 30 follicles measuring≥11 mm in diameter on trigger day and/or pre-trigger peak estradiol exceeding 10 000 pg/mL.which was also the feature of women with established severe early OHSS followed by gonadotrophin-releasing hormone agonist(GnRHa)trigger and freeze-all policy that previously have been reported.All patients received a second dose of GnRHa 12 h after the first GnRHa trigger combined with administration of GnRH antagonist at 0.25 mg/day for a period of 3 days from the day of oocyte retrieval onwards.The in vitro fertilization(IVF)outcomes may be preferable compared with a bolus of GnRHa trigger and none of the included patients developed moderate-to-severe OHSS.Moreover,patients'symptoms,reproductive honnone levels and ultrasound findings were improved significantly.This new strategy seems to be efficacious and could be a further supplement of GnRHa trigger with or without applying freeze-all strategy to completely prevent early-onset moderate to severe OHSS,especially for the patients characterized by≥30 follicles measuring≥11 mm in diameter on trigger day and/or pre-trigger peak estradiol exceeding 10 000 pg/mL.Further studies should be performed to compare this regimen with conventional methods of OHSS prevention.

关键词： in-vitro fertilization ovarian hyperstimulation syndrome GnRH agonist GnRH antagonist freeze-all

Basis expansion model for channel estimation in LTE-R communication system

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Digital Communications and Networks 2016年第2期2卷 92-96页

作者： ling deng Zhonghui Chen Yisheng Zhao College of Physics and Information Engineering Fuzhou University No. 2 Xueyuan Road Fuzhou 350108 Fujian China

This paper investigates fast time-varying channel estimation in LTE-R communication systems. The Basis Expansion Model (BEM) is adopted to fit the fast time-varying channel in a high-speed railway communication scenario. The channel impulse response is modeled as the sum of basis functions multiplied by different coefficients. The optimal coefficients are obtained by theoretical analysis. Simulation results show that a Generalized Complex-Exponential BEM (GCE-BEM) outperforms a Complex-Exponential BEM (CE-BEM) and a polynomial BEM in terms of Mean Squared Error (MSE). Besides, the MSE of the CE-BEM decreases gradually as the number of basis functions increases. The GCE-BEM has a satisfactory performance with the serious fading channel.

关键词： Channel estimation Basis expansion model LTE-R

Universal adversarial examples and perturbations for quantum classifiers

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National Science Review 2022年第6期9卷 48-55页

作者： Weiyuan Gong Dong-ling deng Center for Quantum Information Institute for Interdisciplinary Information Sciences (ⅢS) Tsinghua University Shanghai Qi Zhi Institute

Quantum machine learning explores the interplay between machine learning and quantum physics, which may lead to unprecedented perspectives for both fields. In fact, recent works have shown strong evidence that quantum computers could outperform classical computers in solving certain notable machine learning tasks. Yet, quantum learning systems may also suffer from the vulnerability problem: adding a tiny carefully crafted perturbation to the legitimate input data would cause the systems to make incorrect predictions at a notably high confidence level. In this paper, we study the universality of adversarial examples and perturbations for quantum classifiers. Through concrete examples involving classifications of real-life images and quantum phases of matter, we show that there exist universal adversarial examples that can fool a set of different quantum classifiers. We prove that, for a set of k classifiers with each receiving input data of n qubits, an O(ln [k]/2~n) increase of the perturbation strength is enough to ensure a moderate universal adversarial risk. In addition, for a given quantum classifier, we show that there exist universal adversarial perturbations, which can be added to different legitimate samples to make them adversarial examples for the classifier. Our results reveal the universality perspective of adversarial attacks for quantum machine learning systems, which would be crucial for practical applications of both near-term and future quantum technologies in solving machine learning problems.

关键词： quantum machine learning quantum classifiers adversarial examples measure concentration quantum no-free-lunch theorem

Flexible thermoelectric generator and energy management electronics powered by body heat

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Microsystems & Nanoengineering 2023年第4期9卷 293-301页

作者： Shuai Yang Yumei Li ling deng Song Tian Ye Yao Fan Yang Changlei Feng Jun Dai Ping Wang Mingyuan Gao College of Engineering and Technology Southwest University400716 ChongqingChina Chongqing Key Laboratory of Agricultural Equipment in Hilly Area 400716 ChongqingChina Gies College of Business University of Illinois at Urbana–ChampaignChampaignIL 61820USA Department of Orthopedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopedicsRuijin HospitalShanghai Jiao Tong University School of Medicine200025 ShanghaiChina School of Mechatronical Engineering Beijing Institute of Technology100081 BeijingChina School of Civil Engineering Southwest Jiaotong University610031 ChengduChina

Uninterrupted,efficient power supplies have posed a significant hurdle to the ubiquitous adoption of wearable devices,despite their potential for revolutionizing human‒machine interactions.This challenge is further compounded by the requirement of these devices to supply dependable energy for data-intensive sensing and transmission.Traditional thermoelectric solutions fail to deliver satisfactory performance under conditions of extremely low voltages.Here,we present a novel solution of a wearable thermoelectric generator integrated with an energy management system,which is capable of powering sensors and Bluetooth by harnessing body heat.Distinct from previous works,our innovation lies in its ability to consistently operate even with a minimal temperature difference(i.e.,4 K)between the human skin and the ambient environment,ensuring reliable data transmission within a time as short as 1.6 s.Furthermore,our system can recharge utilizing body heat under ultralow voltage conditions(30 mV).Our developed system provides a novel pathway for the continuous,reliable monitoring of self-contained wearable devices without depending on batteries.

关键词： generator utilizing body

Deletion of the topoisomeraseⅢgene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control

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Journal of Genetics and Genomics 2011年第6期38卷 253-259页

作者： Xiyang Li Li Guo ling deng Deqin Feng Yi Ren Yindi Chu Qunxin She Li Huang State Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China Archaea Centre Department of Biology Copenhagen University Ole Maalces Vej 5 DK-2200N Copenhagen Denmark

Topoisomerase III （topo III）, a type IA topoisomerase, is widespread in hyperthermophilic archaea. In order to interrogate the in vivo role of archaeal topo III, we constructed and characterized a topo III gene deletion mutant of Sulfolobus islandicus. The mutant was ,viable but grew more slowly than the wild-type strain, especially in a nutrient-poor medium. Flow cytometry analysis revealed changes of the mutant in growth cycle characteristics including an increase in proportion of cells containing either more than two genome equivalents or less than one genome equivalent in exponentially-growing cultures. As shown by fluorescence microscopy, a fraction of mutant cells in the cultures were drastically enlarged, and at least some of the enlarged cells were apparently capable of resuming cell division. The mutant also shows a different tran- scriptional profile from that of the wild-type strain. Our results suggest that the enzyme may serve roles in chromosomal segregation and control of the level of supercoiling in the cell.

关键词： Hyperthermophilic archaea Sulfolobus islandicus Topoisomerase III topA deletion Phenotype

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数控机床故障预测研究

现代工业经济和信息化 2024年第1期14卷 110-113页

作者：李晟邓玲新余学院工程训练中心江西新余338000

数控机床故障会导致生产效率下降、产品质量问题和维修成本增加等一系列问题。旨在开展数控机床故障预测研究,通过问题分析、算法优化、信号处理、特征提取以及数据采集等步骤,以提前识别数控机床可能出现的故障,从而降低故障对生产和... 详细信息

数控机床故障会导致生产效率下降、产品质量问题和维修成本增加等一系列问题。旨在开展数控机床故障预测研究,通过问题分析、算法优化、信号处理、特征提取以及数据采集等步骤,以提前识别数控机床可能出现的故障,从而降低故障对生产和质量的不良影响。

关键词：数控机床故障预测

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冬季运动智能柔性人台关键技术开发

纺织学报 2024年第2期45卷 221-230页

作者：何崟邓凌林美霞李倩倩肖爽刘皓刘莉天津工业大学纺织科学与工程学院天津300387 天津工业大学智能可穿戴电子纺织品研究所天津300387 北京服装学院服装艺术与工程学院北京100029

为精确获得运动姿态下服装对运动员整体和局部关键部位的减阻效果,基于运动员冬季运动动态姿势的三维人体数据,合理构建人台硬质内壳与柔性皮肤层的结构,并结合空气动力学等方法设计薄膜压电传感器的置入点位,为人台搭建完整的传感系统... 详细信息

为精确获得运动姿态下服装对运动员整体和局部关键部位的减阻效果,基于运动员冬季运动动态姿势的三维人体数据,合理构建人台硬质内壳与柔性皮肤层的结构,并结合空气动力学等方法设计薄膜压电传感器的置入点位,为人台搭建完整的传感系统,开发了一款冬季运动智能柔性人台,并对该柔性人台进行了实际的风洞测试。结果表明,该人台可实现多点压力信号实时同步采集,不仅可得到人体局部关键部位的具体阻力数据,还可模拟测试速滑运动员在运动情况下穿着不同材料或不同结构设计的竞赛服装的减阻效果,测试竞赛服装不同部位的减阻情况。智能人台发挥了柔性传感器在服装减阻结构设计中的应用价值,使服装减阻测试更为简单和精确。

关键词：柔性人台柔性传感器服装减阻速滑服冬季运动