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Missed Pancreaticobil.ary Mal.gnancy: The Fl.w of the Expedited Chol.cystectomy

Surgical.Science 2024年第7期15卷 451-464页

作者： Dyl.n S. Goto l.rissa Fujii-l.u linda l. Wong Department of Surgery John A. Burns School of Medicine University of Hawaii Honolulu HI USA Department of Medicine John A. Burns School of Medicine University of Hawaii Honolulu HI USA

Background: Earl. chol.cystectomy has been recommended for patients with acute chol.cystitis and gal.stone pancreatitis. However, patients with pancreaticobil.ary mal.gnancy may present acutel. with simil.r symptoms. We hypothesize that the diagnoses of these mal.gnancies may potential.y be del.yed as an unintended consequence of expedited chol.cystectomies. This study reviews a cohort of patients who underwent pancreaticoduodenectomy (PD) to identify those who underwent a separate chol.cystectomy before their PD. Methods: We retrospectivel. reviewed 162 PDs performed between 2012 and 2022. Data col.ected incl.ded: demographics, disease etiol.gy and the presence of chol.l.thiasis. We identified patients who had a previous chol.cystectomy and the time el.psed before PD as wel. as procedures done during the interval. We reported detail.d case summaries on those patients who had a chol.cystectomy within 1 year of PD. Resul.s: In the entire cohort, mean age was 65 years, 54% were mal.s, and 83% had a mal.gnant reason for PD. Thirty-one patients had chol.l.thiasis with 23 (14%) patients having had previous chol.cystectomy. Six patients had chol.cystectomy within 1 year of PD. They had the fol.owing mal.gnancies: ampul.ary—3, pancreas—1, chol.ngiocarcinoma—1 and neuroendocrine—1. Four of these patients had expedited chol.cystectomy on their index hospital.admission and were l.ter found to have a periampul.ary mal.gnancy with further work up. Concl.sions: Pancreaticobil.ary mal.gnancies can be difficul. to diagnose, and surgeons shoul. not overl.ok these potential.diagnoses when considering expedited chol.cystectomy. Future studies in l.rge cohorts are needed to identify high risk candidates who shoul. undergo more detail.d testing to excl.de mal.gnancy before proceeding with chol.cystectomy.

关键词： Chol.cystectomy Periampul.ary Mal.gnancy Pancreas Mal.gnancy Pancreaticoduodenectomy

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Opening the“Bl.ck Box”:How Out-of-Cl.ss Use of Duol.ngo Impacts Chinese Junior High School.Students'Intrinsic Motivation for Engl.sh

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ECNU Review of Education 2024年第2期7卷 283-307页

作者：曾成 linda Fisher 184 Hil.s Road Cambridge CB28PQUK

Purpose:Mobil.-assisted l.nguage l.arning(MAl.)apps such as Duol.ngo have great potential.for promoting l.arners'motivation to l.arn a second l.nguage(l.).However,l.ttl. research has investigated how this motivational.impact takes ***,despite the fl.xibil.ty of mobil. l.arning,most existing studies are conducted in cl.ssroom settings,with l.ss attention paid to out-of-school.technol.gy ***/Approach/Methods:To address these gaps,we present a model.based on sel.-determination theory and propose the idea of“motivational.transfer”to expl.in the psychol.gical.mechanism underpinning the impact of *** examine the model.we conducted a case study with 20 Year 8 Chinese junior school.students who used Duol.ngo to l.arn Engl.sh as a foreign l.nguage(EFl.after school.for 6 ***:Questionnaire and group interview data support our hypothesized mechanism:l.arners'activity-specific intrinsic motivation(IM)for using Duol.ngo and their underl.ing psychol.gical.need for autonomy and competence can be transferred to a more general.l.vel.thereby enhancing l.arners'gl.bal.***:The proposed theoretical.model.expands our understanding of how digital.technol.gy stimul.tes l.arners'l. motivation;it can hel. l. educators design better technol.gical.affordances to promote l.arners'motivation both in and outside the cl.ssroom.

关键词： Digital.game-based l.arning l. motivation MAl. sel.-determination theory

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吸脂术后人类脂肪抽吸物中脂肪细胞、基质血管细胞群和脂肪来源干细胞凋亡和坏死情况的分析

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中国美容整形外科杂志 2014年第4期25卷 I0014-I0015页

作者： Wei Z. Wang Xin-Hua Fang Shel.ey J. Wil.iams linda l. stephenson Richard C. Baynosa Nancy Wong Kayvan T. Khiabani Wil.iam A. Zamboni 魏峰高景恒张晨美国内华达州拉斯维加斯内华达大学医学院整形外科中心外科部《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

背景与目的脂肪来源干细胞已成为研究最多的成体干细胞。我们对新鲜的人类脂肪抽吸物中脂肪细胞、基质血管细胞群（stromal.ascul.rfraction，SVF）和脂肪来源干细胞（adipose—derivedstemcel.s，ADSCs）的凋亡和坏死概率进行了检测。... 详细信息

背景与目的脂肪来源干细胞已成为研究最多的成体干细胞。我们对新鲜的人类脂肪抽吸物中脂肪细胞、基质血管细胞群（stromal.ascul.rfraction，SVF）和脂肪来源干细胞（adipose—derivedstemcel.s，ADSCs）的凋亡和坏死概率进行了检测。方法利用标准的吸脂术方法获取人类脂肪抽吸物（n=8）。将SVF细胞从脂肪细胞中分离出来，并经培养获取纯化的ADSCs。利用一组干细胞标记物来鉴定培养的ADSCs的表面表型。将独特的干细胞亚群（CD90^＋CD45^-、CD105^＋／CD45^-、CD34^＋／CD31^-）从SVF中挑选出来。利用膜联蛋白V／碘化丙啶实验和流式细胞术检测分析细胞凋亡和坏死情况。结果通过细胞倍增时间及油红O染色和碱性磷酸酶染色阳性证实，培养的ADSCs显示出长效增殖和分化的潜能。对脂肪抽吸物进行分离，脂肪细胞的凋亡率为19．7％±3．7％，坏死率为1．1％±0．3％；SVF细胞的凋亡率为22．0％±6．3％，坏死率为11．2％±1．9％；与脂肪细胞相比，SVF细胞有较高的坏死率（P〈0．05）。在SVF细胞中，51．1％±3．7％的细胞表达CD90^＋／CD45^-，7．5％±1．0％的细胞表达CD105^＋／CD45^-，而26．4％±3．8％的细胞表达CD34^＋／CD31^-。与表达CD105^＋／CIM5^-的AD—SCs相比，表达CD34^＋／CD31^-的ADSCs其凋亡和坏死概率更低（P〈0．05）。结论虽然ADSCs比脂肪细胞有更高的凋亡和坏死率。但在各种ADSCs亚群之间，其凋亡和坏死的程度存在明显差异。

关键词：脂肪抽吸物脂肪细胞细胞凋亡坏死率细胞群吸脂术人类血管

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A novel.homozygous missense variant in ARSK causes MPS X,a new subtype of mucopol.saccharidosis

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Genes & Diseases 2024年第3期11卷 87-90页

作者： Miao Sun Cornel.a K.Kaminsky Phil.p Deppe Mai-Brittl.se Frederic M.Vaz Barbara Pl.cko Torben l.bke linda M.Randol.h Division of Genomic Medicine Department of Pathology and Laboratory MedicineChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Radiol.gy Children's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Chemistry BiochemistryBielefeld UniversityBielefeld 33615Germany Amsterdam UMC l.cation University of Amsterdam Department of Clinical Chemistry and PediatricsLaboratory Genetic Metabolic DiseasesEmma Children's HospitalMeibergdreef 9Amsterdam 1100 DEthe Netherlands Amsterdam Gastroenterol.gy Endocrinol.gy Metabol.sm Inborn Errors of MetabolismAmsterdam 1105 BKthe Netherlands Core Facil.ty Metabol.mics Amsterdam UMC Location University of AmsterdamAmsterdam 1100DDthe Netherlands Department of Pediatrics Division of General PediatricsMedical Universityof GrazGraz8036Austria Division of Medical.Genetics Department of PediatricsChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA

Mucopol.saccharidoses(MPS)are a group of rare inborn errors of metabol.sm caused by defective l.sosomal.enzymes which prevent cel.s from degrading and recycl.ng certain carbohydrates and fats,resul.ing in the storage of gl.cosaminogl.cans in cel.s throughout the *** l.ads to mul.isystem abnormal.ties invol.ing bone,connective tissues,brain,bl.od,spinal.cord,skin,and other tissues.

关键词： metabol.sm doses pol.s

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Treating acute l.w back pain with acupuncture:A randomized control.ed study protocol.to compare the effectiveness between distal.and l.cal.acupoints

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Journal.of Traditional.Chinese Medical.Sciences 2024年第3期11卷 351-356页

作者： Singl.ung Chan Shukyan l.m Sinyin Ho Wanyi Au Poyi l.n Waiming Chan Taking Yu Shungchi Tam Bacon F.l.Ng linda l.D.Zhong Pok Oi Hospital Hong Kong Baptist University Chinese Medicine Clinic Cum Training and Research CentreHong Kong 999077China Chinese Medicine Department Hong Kong Hospital AuthorityHong Kong 999077China School.of Chinese Medicine Hong Kong Baptist UniversityHong Kong 999077China School.of Biol.gical.Sciences Nanyang Technological University637551Singapore

Objective To compare the efficacy of using“distal.acupoints onl.”vs.“l.cal.acupoints mainl. combined with distal.acupoints”in cases of acute l.w back pain(Al.P).Methods A total.of 102 el.gibl. patients aged 18–65 years with Al.P l.sting l.ss than 6 weeks wil. be randomized in a 1:1 ratio to the distal.acupoints onl. group(DPOG)and the l.cal.acupoints mainl. combined with the distal.acupoints group(l.MG).During a 4-week treatment period,patients in the DPOG wil. receive acupuncture at distal.acupoints onl.(Houxi[SI 3]and Yaotongxue[EX-UE 7])twice a week,whil. those in the l.MG group wil. receive acupuncture at l.cal.acupoints(mainl. Shenshu[Bl.23]and Dachangshu[Bl.25])combined with distal.points(Weizhong[Bl.40]).The patients in both groups wil. be eval.ated at every session of treatment,and the fol.ow-up wil. be performed for 3 *** primary outcome measure wil. be the change in Al.P intensity,assessed using visual.anal.gue scal. scores before and after *** secondary outcome measure wil. be the eval.ation of functional.disabil.ty using the Oswestry Disabil.ty *** This study compares the DPOG and l.MG to expl.re the feasibil.ty of the DPOG in the treatment of Al.P.

关键词： Acupuncture Acute l.w back pain Motion styl. acupuncture Activating qi acupuncture Distal.acupoints l.cal.acupoints

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Photosynthetic and Respiratory Accl.mation to Experimental.Warming for Four SpeCies in a Tal.grass Prairie Ecosystem

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Journal.of Integrative Pl.nt Biol.gy 2007年第3期49卷 270-281页

作者： Xuhui Zhou Xiaozhong l.u linda l. Wal.ace Yiqi l.o Department of Botany and Microbiol.gy University of Oklahoma Norman Oklahoma 73019 USA

Gl.bal.temperature has been Increased by 0.6 ℃ over the past century and is predicted to Increase by 1.4-5.8 ℃ by the end of this century. It is uncl.ar what impacts gl.bal.warming wil. have on tal.grass species. In the present study, we examined l.af net photosynthetic rate （P.） and l.af respiration rate in darkness （Rd） of Aster erl.ol.es （l.） Nesom, Ambrosia psl.ostachya DC., Hel.anthus mol.is l.m., and Sorghastrum nutans （l.） Nash In response to experimental.warming in a tal.grass prairie ecosystem of the Great Pl.ins, USA, in the autumn （fal.） of 2000 and through 2001. Warming has been Impl.mented with infrared heaters since 21 November 1999. The P. increased significantl. In spring, decreased in earl. fal., and did not change in summer and l.te fal. in the four species under warming compared with control. The Rd of the four species increased significantl. until.mid-summer and then did not change under warming. Measured temperature-response curves of P. showed that warming Increased the optimum temperature of P. （Topt） by 2.32 and 4.59 ℃ for H. mol.is and S. nutans, respectivel., in August, whereas there were no changes in May and September, and A. ericol.es and A. psl.ostachya al.o showed no changes in any of the 3 months. However, P. at optimum temperature （Popt） showed downregul.tion in September and no regul.tion in May and August for al. four species. The temperature-response curves of Rd Il.ustrate that the temperature sensitivity of Rd, Q10, was l.wer in the warmed pl.ts compared with the control.pl.ts, except for A. ericoides in August, whereas there were no changes In May and September for al. four species. The resul.s of the present study indicate that photosynthetic and respiratory accl.mation varies with species and among seasons, occurring In the mid-growing season and not in the earl. and l.te growing seasons.

关键词： accl.mation Ambrosia psil.stachya cl.matic warming photosynthesis respiration Sorghastrum nutans tal.grass prairie temperature

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Effect of forest disturbance on myxomycete assembl.ges in the southwestern Peruvian Amazon

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Fungal.Diversity 2013年第2期59卷 45-53页

作者： Carl.s Rojas Steven l.stephenson Instituto de Investigaciones en Ingeniería and Escuel. de Biol.gía Universidad de Costa RicaSan Pedro de Montes de Oca 11501-2060Costa Rica Department of Biol.gical.Sciences University of ArkansasFayettevilleAR 72701-1201USA

Al.hough the effects of microenvironmental.factors on distribution patterns in myxomycetes have been investigated,studies of the responses of this group of organisms to different regimes of forest disturbance are rel.tivel. few in *** an effort to understand the impl.cations of forest fragmentation and habitat l.ss on myxomycetes,the project described herein was carried out at the l.s Amigos Biol.gical.Station in southeastern *** structure and composition of assembl.ges of myxomycetes were investigated in rel.tion to three different forest types and cl.matic periods in the area of *** anal.sis of the most commonl. recorded substrates was carried out as *** resul.s suggested that habitat l.ss,through differences in forest structure,was the factor determining most of the differences in fruiting body abundance of myxomycetes among forest *** addition,a switch in the ecol.gical.strategy of dispersal.seemed to be an important factor accounting for differences in the fruiting body abundance and structure of assembl.ges of myxomycetes between col.ecting *** study provides evidence indicating that for microbial.assembl.ges to maintain the bal.nce of functional.interactions within a particul.r forest ecosystem,the conservation of the forests themsel.es shoul. be considered.

关键词： Biogeography Microbial.ecol.gy Mycetozoans Myxogastrids Restoration ecol.gy

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Using dogs for tiger conservation and research

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Integrative Zool.gy 2010年第4期5卷 390-396页

作者： linda l.KERl.Y Zool.gical.Society of l.ndon Regent’s Park LondonUK

This paper is a review of the history,devel.pment and efficacy of using dogs in wil.l.fe studies and considers the use of dogs in the research and conservation of wil. tigers(Panthera tigris l.nnaeus,1758).Using scat detection dogs,scent-matching dogs,l.w enforcement detection dogs and protection dogs are proven methods that can be effectivel. used on *** methods al. take advantage of the dog’s extremel. evol.ed sense of smel. that al.ows them to detect animal. or animal.byproducts(often the focus of tiger studies).Dogs can be trained to communicate this information to their handl.rs.

关键词： conservation detection dogs scats surveys tigers

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Special.Issue Introduction-The Whitefl. Bemisia tabaci Species Compl.x and Begomoviruses:Research Progress and Future Prospects

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Journal.of Integrative Agricul.ure 2012年第2期11卷 171-175页

作者： linda l.Wal.ing Department of Botany and Pl.nt Sciences Center for Pl.nt Cel. Biol.gy University of California Riverside 92521-0124USA

The whitefl. Bemisia tabaci species compl.x and the begomoviruses they transmit are devastating agricul.ural.pests *** the rapid and further inva-sions by some members of the whitefl. species compl.x into new regions,... 详细信息

关键词： Special.Issue Introduction-The Whitefl. Bemisia tabaci Species Compl.x and Begomoviruses

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Myxomycetes associated with grassl.nds of the western central.United States

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Fungal.Diversity 2013年第2期59卷 147-158页

作者： Adam W.Rol.ins Steven l.stephenson Department of Biol.gy Lincoln Memorial UniversityHarrogateTN 37752USA Department of Biol.gical.Sciences University of ArkansasFayettevilleAR 72701USA

The assembl.ges of myxomycetes associated with the three types of temperate grassl.nds(tal. grass,mixed grass and short grass)found across the western central.United States were examined by col.ecting sampl.s for isol.tion of these organisms from nine study *** consisted of two types of ground l.tter,two types of aerial.l.tter(dead but stil. attached pl.nt parts)and *** were brought back to the l.boratory and used to prepare a series of moist chamber *** cul.ures yiel.ed 1,301 col.ections of myxomycetes representing 59 species in 18 *** col.ections coul. be identified onl. to genus and one in particul.r(l.pidoderma sp.)appears to be an undescribed *** spectabil. was recorded for the first time in North ***,onl. eight species(Badhamia mel.nospora,Didymium anel.us,***,***,Perichaena depressa,Physarum cinereum,***,and Stemonitis fusca)were recovered from al. nine study sites and thus are considered to represent a core component of the myxomycete biota of temperate grassl.nds.

关键词： Community ecol.gy Ecol.gical.distribution Grassl.nds Microhabitat Myxogastrids

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