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Automated detection of myopic maculopathy from color fundus photographs using deep convolutional neural networks

Eye and Vision 2024年第4期10卷 11-22页

作者： Jun Li Lilong Wang Yan Gao Qianqian Liang Lingzhi Chen Xiaolei Sun Huaqiang Yang Zhongfang Zhao lina meng Shuyue Xue Qing Du zhichun Zhang Chuanfeng LV Haifeng Xu Zhen Guo Guotong Xie Lixin Xie Qingdao Eye Hospital of Shandong First Medical University 5 Yanerdao RoadQingdao 266071China State Key Laboratory Cultivation Base Shandong Provincial Key Laboratory of OphthalmologyShandong Eye InstituteShandong First Medical University&Shandong Academy of Medical SciencesQingdao 266071China Ping An Healthcare Technology 9F Building BPingAn IFCNo.1-3 Xinyuan South RoadBejing 100027China Shandong Eye Hospital of Shandong First Medical University Jinan 250021China Rongcheng Eye Hospital Weihai 264200China Hospital of PLA Navy Qingdao 266071China Qilu Hospital of Shandong University(Qingdao) Qingdao 266035China Ping An Healthcare and Technology Company Limited hanghai 200030China ping An International Smart City Technology Company Limited Shenzhen 518000China.

Background:Myopic maculopathy(MM)has become a major cause of visual impairment and blindness worldwide,especially in East Asian *** learning approaches such as deep convolutional neural networks(DCNN)have been successfully applied to identify some common retinal diseases and show great potential for the intelligent analysis of *** study aimed to build a reliable approach for automated detection of MM from retinal fundus images using DCNN ***:A dual-stream DCNN(DCNN-DS)model that perceives features from both original images and corresponding processed images by color histogram distribution optimization method was designed for classification of no MM,tessellated fundus(TF),and pathologic myopia(PM).A total of 36,515 gradable images from four hospitals were used for DCNN model development,and 14,986 gradable images from the other two hospitals for external *** also compared the performance of the DCNN-DS model and four ophthalmologists on 3000 randomly sampledfundus ***:The DCNN-DS model achieved sensitivities of 93.3%and 91.0%,specificities of 99.6%and 98.7%,areas under the receiver operating characteristic curves(AUCs)of 0.998 and 0.994 for detecting PM,whereas sensitivities of 98.8%and 92.8%,specificities of 95.6%and 94.1%,AUCs of 0.986 and 0.970 for detecting TF in two external testing *** the sampled testing dataset,the sensitivities of four ophthalmologists ranged from 88.3%to 95.8%and 81.1%to 89.1%,and the specificities ranged from 95.9%to 99.2%and 77.8%to 97.3%for detecting PM and TF,***,the DCNN-DS model achieved sensitivities of 90.8%and 97.9%and specificities of 99.1%and 94.0%for detecting PMand T,***:The proposed DCNN-DS approach demonstrated reliable performance with high sensitivity,specificity,and AUC to classify different MM levels on fundus photographs sourced from *** can help identify MM automatically among the large myopic groups and show great potenti

关键词： Myopic maculopathy Tessellated fundus Pathologic myopia Deep convolutional neural network Color fundus image

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全人类共同价值的多维意蕴解读

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中国高校社会科学 2024年第4期 79-88,158页

作者：徐秦法蒙丽娜广西大学马克思主义学院南宁530004

习近平总书记从全人类的前途命运出发,站在时代发展潮流的高度提出全人类共同价值,是面对世界百年未有之大变局因应世界之变、时代之变和历史之变的关键,这既顺应历史潮流,又符合时代之需。深刻理解全人类共同价值的多维意蕴,有助于共... 详细信息

习近平总书记从全人类的前途命运出发,站在时代发展潮流的高度提出全人类共同价值,是面对世界百年未有之大变局因应世界之变、时代之变和历史之变的关键,这既顺应历史潮流,又符合时代之需。深刻理解全人类共同价值的多维意蕴,有助于共同应对全球性挑战,开创人类美好未来。其一,全人类共同价值是马克思主义基本原理同中华优秀传统文化相结合的产物,凝聚了世界共同发展的价值共识。其二,全人类共同价值是对西方所谓“普世价值”的超越,擘画了文明交流互鉴的美好图景。其三,全人类共同价值是回应“世界之问”的“中国答案”,彰显了化解世界性难题的价值力量。其四,全人类共同价值为世界共同发展贡献中国智慧和中国方案,展现了中国负责任大国的作为与担当。

关键词：全人类共同价值人类命运共同体价值共识

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污染信息公开与公众的回应——来自房地产市场的证据

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经济学（季刊） 2024年第1期24卷 154-171页

作者：蒙莉娜余华义陈琦悦计量经济学教育部重点实验室(厦门大学) 厦门大学经济学院经济研究所与王亚南经济研究院福建省统计科学重点实验室(厦门大学) 中国人民大学公共管理学院土地管理系中国工商银行业务研发中心

本文选取2009—2018年间中国20座城市5 000个住宅小区的交易数据,探讨污染信息公开对周围住宅小区房价的影响。结果发现污染信息披露后公众显著降低了对污染企业周边住宅的支付意愿,不同的污染类型对交易价格造成的影响有较大差异。进... 详细信息

本文选取2009—2018年间中国20座城市5 000个住宅小区的交易数据,探讨污染信息公开对周围住宅小区房价的影响。结果发现污染信息披露后公众显著降低了对污染企业周边住宅的支付意愿,不同的污染类型对交易价格造成的影响有较大差异。进一步的机制分析表明由于污名效应的存在,公众对退出企业附近小区环境的支付意愿仍持续下降。本文扩展了污染信息公开而非环境质量本身如何影响市场支付意愿的研究,为政府评估污染信息公开效应提供了的证据。

关键词：污染信息公开房地产市场污名效应

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《外科精义》外治疗法浅析

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江西中医药 2024年第5期55卷 18-20页

作者：孟丽娜甘肃省庆阳市中医医院骨伤一科甘肃庆阳745000

元代名医齐德之所著《外科精义》对于痈疽及疮疡等外科疾患的治疗有独特见解。该书吸收总结了元代以前的医学著作中有关外科疾患的论治经验;记载了砭镰、贴熁、溻渍、针烙、灸疗、追蚀疮肿及外科疾病调护等外治方法。对该著作的研究有... 详细信息

元代名医齐德之所著《外科精义》对于痈疽及疮疡等外科疾患的治疗有独特见解。该书吸收总结了元代以前的医学著作中有关外科疾患的论治经验;记载了砭镰、贴熁、溻渍、针烙、灸疗、追蚀疮肿及外科疾病调护等外治方法。对该著作的研究有助于中医外科的发展及中医外治疗法的传承,对后世外科的发展意义深远。

关键词：齐德之外科精义外治疗法调护

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自身免疫性胃炎与胃肿瘤的研究进展

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胃肠病学 2024年第1期29卷 57-61页

作者：励梦云孟立娜浙江中医药大学附属第一医院消化内科、浙江省消化道疾病病理生理重点实验室国家中医药管理局高水平中医药重点学科(中医脾胃病学) 310006

自身免疫性胃炎(AIG)是一种由自身免疫功能异常所致的胃炎,临床常表现为恶性贫血或神经系统症状,内镜下通常可见胃体黏膜萎缩,可伴有血清抗壁细胞抗体和(或)抗内因子抗体阳性。有研究表明,AIG是胃神经内分泌瘤和胃癌的危险因素,因此内... 详细信息

自身免疫性胃炎(AIG)是一种由自身免疫功能异常所致的胃炎,临床常表现为恶性贫血或神经系统症状,内镜下通常可见胃体黏膜萎缩,可伴有血清抗壁细胞抗体和(或)抗内因子抗体阳性。有研究表明,AIG是胃神经内分泌瘤和胃癌的危险因素,因此内镜下诊断并随访监测AIG至关重要。本文就AIG与胃肿瘤的研究进展作一综述。

关键词：自身免疫性胃炎胃神经内分泌瘤胃肿瘤诊断治疗

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Influence of mechanical alloying time on the properties of Fe_3Al intermetallics prepared by spark plasma sintering

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Journal of University of Science and Technology Beijing 2007年第4期14卷 331-334页

作者： Chengchang Jia Qing He Jie meng lina Guo Materials Science and Engineering School University of Science and Technology Beijing Beijing 100083 China

The Fe3Al-based intermetallics were prepared by mechanical alloying and spark plasma sintering （SPS）, and the influence of milling time on the properties of materials was investigated. The phase identification was investigated by X-ray, and the surface morphology and fractography were observed by scanning electron microscope （SEM）. The mechanical properties such as bending strength, strain, and microhardness were tested. The results show that Fe reacts with Al completely to form Fe3Al during short SPS processing time. The relative densities of the sintered samples were nearly 100%. The mechanical properties of the sintered samples can be improved along with the milling time. The representative values are the bend strength of 1327 MPa and the microhardness of 434.

关键词： Fe3A1 intermetallics mechanical properties mechanical alloying and milling powder metallurgy

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深冷轧工艺在高性能金属材料制备中的应用

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中国高新科技 2024年第10期 134-135,140页

作者：刘丹丹孟丽娜郑州工业应用技术学院河南郑州451100

文章对深冷轧工艺在高性能金属材料制备中的应用展开深入探讨与研究,基于对深冷轧工艺原理和特点的分析,结合高性能金属材料的特性,从残余奥氏体改变、超细碳化物析出、组织晶粒细化3个方面,对深冷轧工艺在高性能金属材料制备中的应用... 详细信息

文章对深冷轧工艺在高性能金属材料制备中的应用展开深入探讨与研究,基于对深冷轧工艺原理和特点的分析,结合高性能金属材料的特性,从残余奥氏体改变、超细碳化物析出、组织晶粒细化3个方面,对深冷轧工艺在高性能金属材料制备中的应用进行详细设计。研究结果表明,深冷轧工艺为高性能金属材料的制备提供了一种有效的途径,可以显著提高材料的性能。

关键词：深冷轧工艺材料制备等轴压力异步轧制

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Urban Inclusiveness and Entrepreneurship:Evidence from Microdata on Migrants

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China Finance and Economic Review 2020年第2期9卷 89-111页

作者： Yinggang Zhou lina meng Xueping Lin Center for Macroeconomic Research Wang Yanan Institute for Studies in Economics(WISE) School of Economics Xiamen University School of Economics Xiamen UniversityChina

With the progressive reforms of China’s household registration system,China has unleashed its demographic dividends over the time and promoted the economic *** by the new vision of development,urban inclusiveness,especially the urban inclusiveness to the migrant population,will become a force for driving economic *** the 2016 China Migrants Dynamic Survey(CMDS)dataset,we measure urban inclusiveness with the level of migrants’access to same public services and social security as local residents and explore the effects of urban inclusiveness on migrants’*** results show that urban inclusiveness encourages migrants to start businesses and has a positive effect on the level of *** urban environmental conditions and heterogeneity of individual laborers have different regulating effects on the influence of urban inclusiveness on individual entrepreneurial *** findings offer important inspirations for policy making in reforming the Chinese urban systems and promoting migrants’entrepreneurship.

关键词： urban inclusiveness migrant population entrepreneurship

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Acupuncture effects on the hippocampal cholinergic system in a rat model of neuropathic pain

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Neural Regeneration Research 2012年第3期7卷 212-218页

作者： Junying Wang Junling Liu Shuping Chen Yonghui Gao Fanying meng lina Qiao Institute of Acu-moxibustion China Academy of Chinese Medical Sciences Beijing 100700 China

The present study observed the effects of repeated electroacupuncture of Zusanli （ST36） and Yanglingquan （GB34） on expression of hippocampal acetylcholinesterase, vesicular acetylcholine transporter, and muscarinic M1 receptor mRNA in chronic constrictive injury （neuropathic pain） and/or ovariotomy rats. Results demonstrated increased expression of hippocampal acetylcholinesterase, vesicular acetylcholine transporter, and muscarinic M1 receptor mRNA, as well as decreased pain threshold, in a rat model of chronic neuropathic pain after electroacupuncture. The effects of electroacupuncture increased with prolonged time, but the above-mentioned effects decreased in memory-deficient animals. Results indicated that repeated electroacupuncture has a cumulative analgesic effect, which is closely associated with upregulation of acetylcholinesterase and vesicular acetylcholine transporter activity, as well as M1 receptor mRNA expression and memory.

关键词： acetylcholinesterase chronic pain cumulative effect electroacupuncture analgesia hippocampus M1R mRNA expression vesicular acetylcholine transporter

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Improved perovskite solar cell efficiency by tuning the colloidal size and free ion concentration in precursor solution using formic acid additive

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Journal of Energy Chemistry 2020年第2期29卷 43-51页

作者： lina meng Qingbo Wei Zhou Yang Dong Yang Jiangshan Feng Xiaodong Ren Yucheng Liu Shengzhong(Frank)Liu Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationShaanxi Key Laboratory for Advanced Energy DevicesShaanxi Engineering Lab for Advanced Energy TechnologyInstitute for Advanced Energy MaterialsSchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an 710119ShaanxiChina Key Laboratory of Chemical Reaction Engineering of Shaanxi Province College of Chemistry and Chemical EngineeringYan'an UniversityYan'an 716000ShaanxiChina iChEM Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina

Improving the quality of the perovskite active layer is crucial to obtaining high performance perovskite solar cells(PSCs). In this work, by introducing formic acid into the formamidinium lead iodide(FAPbI3)precursor solution, we managed to achieve reduced colloidal size in the solution, leading to more uniform deposition of FAPbI3 film with lower trap state density and higher carrier mobility. The solar cells based on the FAPbI3 absorber layer modified with formic acid show significantly better photovoltaic performance than that on the reference FAPbI3 film without formic acid. The device performance shows a close correlation with the colloidal size. Within the range studied from 6.7 to 1.0 nm, the smaller the colloidal size is, the higher the solar cell efficiency. More specifically, the cell efficiency is improved from17.82% for the control cell without formic acid to 19.81% when 0.764 M formic acid was used. Formic acid has also been added into a CH3NH3PbI3(MAPbI3) precursor solution, which exhibits a similar effect on the resulting MAPb I3 films and solar cells, with efficiency improved from 16.07% to 17.00%.

关键词： Perovskite solar cell Crystallization Formic acid Additive

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