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Hemoglobin loss method calculates blood loss during pancreaticoduodenectomy and predicts bleeding-related risk.factors

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 419-428页

作者： Chao Yu Yi-Min lin Guo-Zhe Xian Department of Hepatobiliary Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina

BACk.ROUND The common clinical method to evaluate blood loss during pancreaticoduoden-ectomy(PD)is visual inspection,but most scholars believe that this method is extremely subjective and ***,there is no accurate,objective me-thod to evaluate the amount of blood loss in PD *** retrospectively analyzed the clinical data of 341 patients who underwent PD in Shandong Provincial Hospital from March 2017 to February *** to different surgical methods,they were divided into an open PD(OPD)group and a laparoscopic PD(lPD)*** differences and correlations between the in-traoperative estimation of blood loss(IEBl)obtained by visual inspection and the intraoperative calculation of blood loss(ICBl)obtained using the Hb loss method were ***,IEBl and perioperative calculation of blood loss(PCBl)were compared between the two groups,and single-factor regression analysis was *** There was no statistically significant difference in the preoperative general patient information between the two groups(P>0.05).PD had an ICBl of 743.2(393.0,1173.1)ml and an IEBl of 100.0(50.0,300.0)ml(Plso a certain correlation between the two(r=0.312,Ple-factor analysis of ICBl showed that a history of diabetes[95%confidence interval(CI):53.82-549.62;P=0.017]was an independent risk.factor for *** addition,the single-factor analysis of PCBl showed that body mass index(BMI)(95%CI:0.62-76.75;P=0.046)and preoperative total bilirubin>200μmol.l.95%CI:7.09-644.26;P=0.045)were independent risk.factors for *** ICBls of the lPD group and OPD group were 767.7(435.4,1249.0)ml and 663.8(347.7,1138.2)ml,respectively(P>0.05).The IEBl of the lPD group 200.0(50.0,200.0)ml was slightly greater than that of the OPD group 100.0(50.0,300.0)ml(P>0.05).PCBl was greater in the lPD group than the OPD group[1061.6(612.3,1632.3)ml vs 806.1(375.9,1347.6)ml](PlUSION The ICBl in patients who underwent PD was greater than

关键词： Pancreaticoduodenectomy Hemoglobin loss Calculated blood loss Estimated blood loss

Fangji Fuling Decoction Alleviates Sepsis by Block.ng MAPk.4/FOXO3A Signaling Pathway

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Chinese Journal of Integrative Medicine 2024年第3期30卷 230-242页

作者： WANG Yi CHEN Ming-qi DAI lin-feng ZHANG Hai-dong WANG Xing Department of Critical Care Medicine Changzhou Hospital of Traditional of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineChangzhouJiangsu Province213000China Department of Critical Care Medicine Jiangsu Province Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing210029China

Objective:To examine the therapeutic effect of Fangji Fuling Decoction(FFD) on sepsis through network.pharmacological analysis combined with in vitro and in vivo ***:A sepsis mouse model was constructed through intraperitoneal injection of 20 mg/k. lipopolysaccharide(lPS).RAW264.7 cells were stimulated by 250 ng/m l.l.S to establish an in vitro cell *** pharmacology analysis identified the k.y molecular pathway associated with FFD in *** ectopic expression and depletion experiments,the effect of FFD on multiple organ damage in septic mice,as well as on cell proliferation and apoptosis in relation to the mitogen-activated protein k.nase 14/Fork.ead Box O 3A(MAPk.4/FOXO3A) signaling pathway,was ***:FFD reduced organ damage and inflammation in lPS-induced septic mice and suppressed lPS-induced macrophage apoptosis and inflammation in vitro(Pk.pharmacology analysis showed that FFD could regulate the MAPk.4/FOXO signaling pathway during *** confirmed by in vitro cell experiments,FFD inhibited the MAPk.4 signaling pathway or FOXO3A expression to relieve lPS-induced macrophage apoptosis and inflammation(Pk.4/FOXO3A signaling pathway to inhibit lPS-induced macrophage apoptosis in the lung tissue of septic mice(Plusion:FFD could ameliorate the lPS-induced inflammatory response in septic mice by inhibiting the MAPk.4/FOXO3A signaling pathway.

关键词： sepsis Fangji Fuling Decoction mitogen-activated protein k.nase 14/Fork.ead Box O 3A signaling pathway inflammatory response apoptosis lung injury Chinese medicine

Free radicals trigger the closure of open pores in lignin-derived hard carbons toward improved sodium-storage capacity

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Journal of Energy Chemistry 2024年第7期94卷 551-559页

作者： Wen-Jun Ji Zong-lin Yi Ming-Xin Song Xiao-Qian Guo Yi-lin Wang Yi-Xuan Mao Fang-Yuan Su Jing-Peng Chen Xian-Xian Wei li-Jing Xie Cheng-Meng Chen CAS k.y laboratory of Carbon Materials Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001ShanxiChina University of Chinese Academy of Sciences Beijing 100049China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China School of Environment and Safety Taiyuan University of Science and TechnologyTaiyuan 030001ShanxiChina

The chemical activation of various precursors is effective for creating additional closed pores in hard carbons for sodium ***,the formation mechanism of closed pores under the influence of pore-forming agents is not well ***,an effective chemical activation followed by a high-temperature self-healing strategy is employed to generate interconnected closed pores in lignin-derived hard carbon(HCs).By systematic experimental design combined with electron paramagnetic res-onance spectroscopy,it can be found that the content of free radicals in the carbon matrix influences the closure of open pores at high *** high activation temperature(>700 C)leads to a low free radical concentration,mak.ng it difficult to achieve self-healing of open pores at high *** activation at 700°C,a balance between pore mak.ng and self-healing is achieved in the final hard carbon.A large number of free radicals triggers rapid growth and aggregation of carbon microcrys-tals,block.ng pre-formed open micropores and creating additional interconnected closed pores in as-obtained hard *** a result,the optimized carbon anode(lk.700-1300)delivers a high reversible capacity of 330.8 mA h g^(-1) at 0.03 A g^(-1),which is an increase of 86 mA h g^(-1) compared to the pristine lignin-derived carbon anode(l-700-1300),and exhibits a good rate performance(202.1 mA h g^(-1) at 1 A g^(-1)).This work.provides a universal and effective guidance for tuning closed pores of hard carbons from otherprecursors.

关键词： Hard carbon Chemical activation Free radical Self-healing Closed pores Sodium ion batteries

Ⅱ型截面双层组合梁摩擦型螺栓连接节点弯矩分配系数

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中国铁道科学 2024年第2期45卷 59-71页

作者：李盛贾云翔郭铮吕文达于本田李林兰州交通大学土木工程学院甘肃兰州730070 中铁第一勘察设计集团有限公司甘肃兰州730030

为探究Ⅱ型截面双层组合梁摩擦型螺栓连接节点翼缘和腹板的弯矩比,通过对3种腹板螺栓布置形式的Ⅱ型截面双层组合梁连接节点接触面滑移特征和力学传递机理的分析,进行Ⅱ型截面组合梁螺栓连接节点弯矩分配系数研究。结果表明:组合梁摩擦... 详细信息

为探究Ⅱ型截面双层组合梁摩擦型螺栓连接节点翼缘和腹板的弯矩比,通过对3种腹板螺栓布置形式的Ⅱ型截面双层组合梁连接节点接触面滑移特征和力学传递机理的分析,进行Ⅱ型截面组合梁螺栓连接节点弯矩分配系数研究。结果表明:组合梁摩擦型螺栓连接节点滑移和力学传力过程可分为翼缘外接触面未完全滑移和完全滑移以及翼缘内接触面完全滑移3个阶段;组合梁摩擦型螺栓连接节点接触面承担弯矩与无连接板截面弯矩之和等于该梁截面处的理论弯矩,腹板接触面承担的弯矩主要由其上的水平摩擦力承担;摩擦型螺栓连接节点接触面上的摩擦力随节点滑移而重新分配,腹板螺栓布置形式对连接节点弯矩分配系数影响明显;根据推出的组合梁摩擦型螺栓连接节点的弯矩分配系数计算式所得结果与数值模拟结果吻合良好,最大误差为7.13%,该计算可用于优化螺栓连接设计。

关键词： Ⅱ型截面双层组合梁摩擦型螺栓连接节点滑移弯矩分配系数

深冷循环热处理下锆基金属玻璃的回春行为调控

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Transactions of Nonferrous Metals Society of China 2024年第2期34卷 582-591页

作者：郭威余圣丁俊吕书林吴树森赵觅华中科技大学材料科学与工程学院材料成形与模具技术全国重点实验室武汉430074 深圳华中科技大学研究院深圳518057 西安交通大学金属材料强度国家重点实验室材料创新设计中心西安710049 华中科技大学航空航天学院武汉430074

研究Zr_(55)Cu_(30)Ni_(5)Al_(10)(摩尔分数,%)金属玻璃在深冷循环处理过程中的回春行为。实验发现,随着循环次数的增加,样品的回春程度更高,表现为更高的弛豫焓与更低的密度。回春程度经200次循环后逐渐饱和,这可能与非晶结构中有限的... 详细信息

研究Zr_(55)Cu_(30)Ni_(5)Al_(10)(摩尔分数,%)金属玻璃在深冷循环处理过程中的回春行为。实验发现,随着循环次数的增加,样品的回春程度更高,表现为更高的弛豫焓与更低的密度。回春程度经200次循环后逐渐饱和,这可能与非晶结构中有限的自由体积含量有关。同时,高循环次数下的样品硬度更低,塑性更好,这与其剪切转变区体积增大有关。此时,更低的剪切面形成能有利于多重剪切带的形成。此外,还发现自由体积含量与样品塑性应变及剪切转变区体积呈线性关系。分子动力学模拟结果还表明,在高冷速下回春程度高的样品会发生原子体积的饱和。

关键词：金属玻璃回春深冷循环热处理循环次数塑性

Enhanced photocatalytic nitrogen fixation performance via in situ constructing BiO_(2-x)/NaNbO_(3) heterojunction

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Chinese Journal of Chemical Engineering 2024年第5期69卷 92-100页

作者： Jiayu Zhang Zhihao Zeng lin Yue Chunran Zhao Xin Hu leihong Zhao Xiuwen Wang Yiming He k.y laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China Heilongjiang Provincial k.y laboratory of Surface Active Agent and Auxiliary School of Chemistry and Chemistry EngineeringQiqihar UniversityQiqihar 161006China Department of Materials Science and Engineering Zhejiang Normal UniversityJinhua 321004China

The fabrication of heterojunction catalysts is an effective strategy to enhance charge separation efficiency,thereby boosting the performance of *** this study,BiO_(2-x)nanosheets were synthesized through a hydrothermal process and loaded onto NaNbO_(3) microcube to construct a series of BiO_(2-x)/NaNbO_(3) heterojunctions for photocatalytic N_(2) *** indicated that 2.5%BiO_(2-x)/NaNbO_(3) had the highest photocatalytic *** NH_(3) production rate under simulated solar light reached 406.4μmol.l.(-1)·g^(-1)·h^(-1),which reaches 2.6 and 3.8 times that of NaNbO_(3) and BiO_(2-x),***_(2-x)nanosheets primarily act as electron trappers to enhance the separation efficiency of charge *** strong interaction between BiO_(2-x)and NaNbO_(3) facilitates the electron migration between ***,the abundant oxygen vacancies in BiO_(2-x)nanosheets may facilitate the adsorption and activation of N_(2),which may be another possible reason of the high photocatalytic activity of the BiO_(2-x)/NaNbO_(3).This study may offer new insights for the development of semiconductor materials in photocatalytic nitrogen fixation.

关键词： Catalyst Solar energy Hydrothermal BiO_(2-x)/NaNbO_(3) Photocatalytic N_(2)-fixation

Recovery of li, Ni, Co and Mn from spent lithium-ion batteries assisted by organic acids: Process optimization and leaching mechanism

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International Journal of Minerals,Metallurgy and Materials 2024年第3期31卷 518-530页

作者： liuyi Ren Bo liu Shenxu Bao Wei Ding Yimin Zhang Xiaochuan Hou Chao lin Bo Chen School of Resources and Environmental Engineering Wuhan University of TechnologyWuhan 430070China State Environmental Protection k.y laboratory of Mineral Metallurgical Resources Utilization and Pollution Control Wuhan University of Science and TechnologyWuhan 430081China Zhejiang New Era Zhongneng Recycling Technology Co. LtdShaoxing 312000China Shenzhen Water Planning&Design Institute Co. LtdShenzhen 518000China

The proper recycling of spent lithium-ion batteries(lIBs)can promote the recovery and utilization of valuable resources,while also negative environmental effects resulting from the presence of toxic and hazardous *** this study,a new environmentally friendly hydro-metallurgical process was proposed for leaching lithium(li),nick.l(Ni),cobalt(Co),and manganese(Mn)from spent lIBs using sulfuric acid with citric acid as a *** effects of the concentration of sulfuric acid,the leaching temperature,the leaching time,the solid-liquid ratio,and the reducing agent dosage on the leaching behavior of the above elements were *** parameters were optimized using response surface methodology(RSM)to maximize the recovery of metals from spent *** maxim-um recovery efficiencies of li,Ni,Co,and Mn can reach 99.08%,98.76%,98.33%,and 97.63%.under the optimized conditions(the sulfuric acid concentration was 1.16 mol.l.the citric acid dosage was 15wt%,the solid-liquid ratio was 40 g/l,and the temperature was 83℃ for 120 min),*** was found that in the collaborative leaching process of sulfuric acid and citric acid,the citric acid initially provided strong reducing CO_(2)^(-),and the transition metal ions in the high state underwent a reduction reaction to produce transition metal ions in the low ***,citric acid can also act as a proton donor and chelate with lower-priced transition metal ions,thus speeding up the dissolution process.

关键词： spent lithium-ion batteries leaching response surface methodology sulfuric acid citric acid

Efficient electroreduction of nitrate via enriched active phases on copper-cobalt oxides

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Chinese Chemical.l.tters 2024年第4期35卷 204-209页

作者： ling Fang Sha Wang Shun lu Fengjun Yin Yujie Dai lin Chang Hong liu Chongqing Institute of Green and Intelligent Technology Chinese Academy of SciencesChongqing 400714China University of Chinese Academy of Sciences Beijing 100049China

Electrochemical conversion of nitrate(NO_(3)~-) to ammonia(NH_(3)) can target two birds with one stone well, in NO_(3)^(-)-containing sewage remediation and sustainable NH_(3) production. However, single metalbased catalysts are difficult to drive high-efficient NO_(3)~- removal due to the multi-electron transfer ***, we present a tandem catalyst with simple structure, Cu-Co binary metal oxides(Cu-Co-O), by engineering intermediate phases as catalytic active species for NO_(3)~- conversion. Electrochemical evaluation,X-ray photoelectron spectroscopy, and in situ Raman spectra together suggest that the newly-generated Cu-based phases was prone to NO_(3)~- to NO_(2)~- conversion, then NO_(2)~- was reduced to NH_(3) on Co-based species. At an applied potential of -1.1 V vs. saturated calomel electrode, the Cu-Co-O catalyst achieved NO_(3)~- -N removal of 90% and NH_(3) faradaic efficiency of 81% for 120 min in 100 m l of 50 mg/l NO_(3)~- -N,consuming only 0.69 k.Wh/mol in a two-electrode system. This study provides a facile and efficient engineering strategy for developing high-performance catalysts for electrocatalytic nitrate conversion.

关键词： NO_(3)^(-)-containing sewage remediation Electrocatalytic reduction Copper-cobalt oxides Tandem reactivity Enriched active phases

Pharmacovigilance guidelines for clinical application of traditional Chinese medicine injections

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Zhongguo Zhongyao Zazhi 2024年第16期49卷 4279-4284页

作者： Fu C.-k. liu H. Wang l.-X. Zou Y.-H. li M.-Q. lin Y.-M. Sun W.-H. Wei X. Hu Y.-E. Xie Y.-M. li Y.-Y. Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences Beijing 100700 China Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100700 China the Third Affiliated Hospital of Changchun University of Chinese Medicine Changchun 130117 China Yunnan Provincial Hospital of Traditional Chinese Medicine Kunming 650021 China General Hospital of Ningxia Medical University Yinchuan 750004 China Wangjing Hospital China Academy of Chinese Medical Sciences Beijing 100102 China

In 2019, the newly revised Drug Administration law of the People′s Republic of China was issued and implemented, clearly proposing that China should establish a pharmacovigilance system. As a new traditional Chinese medicine(TCM) dosage form created in China, TCM injections have been widely used in clinic, and its pharmacovigilance has attracted much attention. In response to this situation, the project team convened a group of clinical, pharmaceutical and evidence-based medicine experts from all over the country to form an expert group, which formulated the Pharmacovigilance guidelines for clinical application of traditional Chinese medicine injections in strict accordance with the requirements of the group standards of the Chinese Association of Chinese Medicine. From the perspective of clinical application and considering the k.y elements of pharmacovigilance for clinical application of TCM injections, the guidelines put forward suggestions on the decision mak.ng of pharmacovigilance for clinical application of TCM injections from four k.y link., namely the monitoring and reporting, signal recognition, risk.assessment and risk.control, according to China′s pharmacovigilance regulations and learning from foreign pharmacovigilance guidelines. © 2024 Zhongguo Zhongyi Yanjiuyuan. All rights reserved.

关键词： group standard guideline pharmacovigilance traditional Chinese medicine injections traditional Chinese medicine pharmacovigilance