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新潮电子 2006年第11期 183-185页

作者：王超 zj（图）

用“盼星星，盼月亮”来形容我等待诺基亚（NOKIA）N91的上市一点也不为过。自打人生拥有第一部随身听以来，随身的音乐就一刻也没有离开过我的生活，从校园生活的磁带随身听。

关键词：诺基亚N91 手机磁带随身听硬盘 NOKIA

Three new polyoxygenated bergamotanes from the endophytic fungus Penicillium purpurogenum IMM 003 and their inhibitory activity against pancreatic lipase

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Chinese Journal of Natural Medicines 2020年第1期18卷 75-80页

作者： XIA Gui-Yang WANG ling-Yan ZHANG Jing-Fang WU Yu-Zhuo GE Guang-Bo WANG Ya-Nan lin Peng-Cheng lin Sheng State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 1Q0050China Institute of Interdisciplinaty Medicine Shanghai University of Traditional Chinese MedicineShanghai 201203China College of Pharmaceutical Sciences Qinghai University for NationalitiesXining 810000China

Purpurolides D–F(1–3),three new polyoxygenated bergamotanes bearing a 6/4/5/5 tetracyclic ring system,were isolated from the endophytic fungus Penicillium purpurogenum IMM *** structures were unambiguously elucidated based on extensive spectroscopic data analyses,13 C NMR chemical shifts calculations coupled with the DP4+probability method,and the calculated and experimental electronic circular dichroism(ECD)*** 1–3 showed significant inhibitory activity against pancreatic lipase(PL).The result highlights that the presence of 3-hydroxylated decanoic acid moiety at C-14 is important for increasing the inhibition potency against PL.

关键词： Penicillium purpurogenum Sesquiterpene lactones Pancreatic lipase inhibitors

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玩酷在指尖 iTch VKB蓝牙虚拟键盘

新潮电子 2006年第11期 177-179页

作者：陈果 zj（图）

一直以来，我心怀对詹姆斯·邦德的无限向往，总希望什么时候也能用那些奇妙的Spy Tools玩酷一把，还好早早地在《新潮电子》申请了试用名额，这次得以有机会在第一时间尝鲜iTch VKB蓝牙虚拟键盘。

关键词：虚拟键盘蓝牙手机笔记本电脑输入速度

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平面铣削陶瓷的回转超声波加工

国外金属加工 1996年第6期17卷 34-40页

作者： PEI,zj 吴希让

在各种用于陶瓷材料的切削方法中，回转超声波加工在获得高材料切除率方面具有很大潜力，并可保持较小的加工压力和得到较小表面损害。但由于刀具有回转运动，回转超声波加工仅限于加工圆孔和凹槽。

关键词：回转超声波加工陶瓷切削平面铣剂超声波

Bone metastases from hepatocellular carcinoma:clinical features and prognostic factors

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Hepatobiliary & Pancreatic Diseases International 2017年第5期16卷 499-505页

作者： Yang Lu Jin-Gen Hu Xiang-Jin lin Xi-Gong Li Department of Orthopedics First Affiliated HospitalZhejiang University School of Medicine Hangzhou 310003 China

BACKGROUND: Bone metastases (BMs) from hepatocellular carcinoma (HCC) is an increasingly common disease in Asia. We assessed the clinical features, prognostic factors, and differences in outcomes related to BMs among patients with different treatments for HCC. METHODS: Forty-three consecutive patients who were diagnosed with BMs from HCC between January 2010 and December 2014 were retrospectively enrolled. The clinical features were identified, the impacts of prognostic factors on survival were statistically analyzed, and clinical data were compared. RESULTS: The median patient age was 54 years; 38 patients were male and 5 female. The most common site for BMs was the trunk (69.3%). BMs with extension to the soft tissue were found in 14 patients (32.5%). Most (90.7%) of the lesions were mixed osteolytic and osteoblastic, and most (69.8%) patients presented with multiple BMs. The median survival after BMs diagnosis was 11 months. In multivariate analyses, survival after BM diagnosis was correlated with Karnofsky performance status (P=0.008) and the Child-Pugh classification (P<0.001); BM-free survival was correlated with progression beyond the University of California San Francisco criteria (P<0.001) and treatment of primary tumors (P<0.001). BMs with extension to soft tissue were less common in liver transplantation patients. During metastasis, the control of intrahepatic tumors was improved in liver transplantation and hepatectomy patients, compared to conservatively treated patients. CONCLUSIONS: The independent prognostic factors of survival after diagnosis of BMs were the Karnofsky performance status and Child-Pugh classification. HCC patients developed BMs may also benefit from liver transplantation or hepatectomy.

关键词： hepatocellular carcinoma bone metastases survival prognostic factors

体育学院不同专业、不同年级学生心肺功能测试结果比较

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中国组织工程研究与临床康复 2007年第39期11卷 7940-7942页

作者：季丽萍冯照军徐州师范大学体育学院江苏省徐州市221116 徐州师范大学生命科学学院江苏省徐州市221116

目的:观察武术运动对体育院校学生心肺功能的影响,及不同专业、不同年级学生心肺功能的差异。方法:于2004-03/07选择徐州师范大学体育学院科研所的大学生志愿者60名进行心肺功能测试。均为男性,身体健康,自愿接受测试。对照组:非系统参... 详细信息

目的:观察武术运动对体育院校学生心肺功能的影响,及不同专业、不同年级学生心肺功能的差异。方法:于2004-03/07选择徐州师范大学体育学院科研所的大学生志愿者60名进行心肺功能测试。均为男性,身体健康,自愿接受测试。对照组:非系统参加体育运动的普通院系健康大学生12名。体育教育专业1组:体育教育专业一年级学生12名;体育教育专业2组:体育教育专业四年级学生12名;民族传统专业1组:民族传统专业一年级专修武术套路二级运动员12名。民族传统专业2组:民族传统专业四年级专修武术套路二级运动员12名。测试前测量受试者的身高、体质量,5组受试者的身高、体质量无差异(P>0.05)。运动强度采用改良Bruce方案,每级运动3min,无间隙自动升级,运动中连续心电监护并记录心电图和心率,同时收集受试者呼出的气体,测出吸氧量和肺通气等。根据参数推算出心输出量[Q=2.9+5VO2(L/min)]。结果:60名受试者均进入结果分析。①安静时民族传统专业1组、民族传统专业2组、体育教育专业1组和体育教育专业2组受试者的心率均低于对照组[(72.6±6.3),(77.4±5.1),(72.2±5.9),(82.7±8.6),(90.2±9.1)次/min,P<0.05],最大心输出量均明显高于对照组[(20.5±2.8),(19.5±2.0),(19.9±1.8),(18.5±1.4),(16.8±1.2)L/min,P<0.01]。体育教育专业2组安静时心率明显高于体育教育专业1组,最大心输出量明显低于体育教育专业1组。②体育专业两组的最大吸氧量、最大通气量、运动时间和运动强度均明显高于对照组[最大吸氧量:(3.4±0.2),(3.2±0.3),(2.8±0.8)L/min;最大通气量:(112.8±10.1),(107.3±8.8),(99.1±8.6)L/min;运动时间:(18.1±1.1),(15.3±1.8),(13.7±1.8)min;运动强度:(6.0±0.4),(5.1±0.5),(4.6±0.6),P<0.05]。体育教育专业2组的最大吸氧量、运动时间和运动强度均低于体育教育专业1组(P<0.05);体育教育专业2组运动时间、运动强度均明显低于民族传统专业2组[运动时间:(15.3±1.8),(17.3±1.1)min;运动强度:(5.1±0.5),(5.7±0.6),P<0.05]。结论:随年级的升高,不同体育专业学生的心肺功能有所下降。武术运动能够提高大学生的心肺功能,民族传统专业和体育教育专业学生的心肺功能无明显差别。

关键词：体育运动民族心率心输出量最大吸氧量心肺功能

Fluorescence Nanoscopy in Neuroscience

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Engineering 2022年第9期16卷 29-38页

作者： Yangyundou Wang Jian lin Qiming Zhang Xi Chen Haitao Luan Min Gu Center for Artificial-Intelligence Nanophotonics School of Optical-Electrical and Computer EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China

Fluorescence nanoscopy provides imaging techniques that overcome the diffraction-limited resolution barrier in light microscopy,thereby opening up a new area of research in biomedical imaging in fields such as ***,we review the foremost fluorescence nanoscopy techniques,including descriptions of their applications in elucidating protein architectures and mobility,the real-time determination of synaptic parameters involved in neural processes,three-dimensional imaging,and the tracking of nanoscale neural *** conclude by discussing the prospects of fluorescence nanoscopy,with a particular focus on its deployment in combination with related techniques(e.g.,machine learning)in neuroscience.

关键词： Fluorescence imaging Diffraction limit Nanoscale resolution Neuroscience

Numerical Simulation Study of Oil-Water Emulsion Separation in an Ultrasonic Field:Effect of Coupling between Acoustic and Flow Field Parameters

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China Petroleum Processing & Petrochemical Technology 2024年第1期26卷 116-125页

作者： Wang Heping lin Yinchao Li Yanggui Zhang Xiaohang Wu Yi Key Laboratory of Engineering Mathematics and Advanced Computing of Nanchang Institute of Technology School of SciencesNanchang Institute of TechnologyNanchang 330099People’s Republic of China Dongguan Key Laboratory of Kunpeng Computing School of Computer ScienceGuangdong University of Science&TechnologyDongguan 523083China State Key Laboratory of Plateau Ecology and Agriculture Qinghai UniversityXining 810016China

In this study,the separation and coalescence of oil-in-water emulsions are explored in an ultrasonic field using the lattice Boltzmann *** simulating the propagation of ultrasonic waves,this study focuses on examining the effects of acoustic wave frequency,the ratio of oil to water components,and the aspect ratio of the boundary on the emulsification and separation processes of oil-water *** following conclusions are drawn.①Frequency affects the speed of oil droplet separation,leading to an increase in droplet size over *** droplets are found near the source,while smaller droplets are distributed throughout the wave web.②As the boundary aspect ratio increases,the emulsification efficiency of the droplets weakens,and the system takes longer to stabilize.③Emulsions with a higher component of oil can better resist acoustic waves.④At the same acoustic frequency,longer wavelength ultrasonic fields promote the formation of uniformly distributed,smaller oil droplets,which is beneficial to the storage of *** numerical simulation results offer insights for optimizing conditions for oil-in-water separation and serve as a numerical reference for the study of oil-in-water emulsion separation in ultrasonic environments.

关键词： lattice Boltzmann method phase separation ultrasound field

Bioactive neolignans and lignans from the roots of Paeonia lactiflora

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Chinese Journal of Natural Medicines 2022年第3期20卷 210-214页

作者： XIA Huan ZHANG Jing-Fang WANG ling-Yan XIA Gui-Yang WANG Ya-Nan WU Yu-Zhuo lin Peng-Cheng XIONG Liang lin Sheng Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China College of Pharmaceutical Sciences Qinghai University for NationalitiesXining 810000China School of Pharmacy Chengdu University of Traditional Chinese MedicineChengdu 611137China

Two new neolignans and one new lignan(1-3)were obtained from the roots of Paeonia *** structures were unambiguously elucidated based on extensive spectroscopic analysis,single-crystal X-ray crystallography,and the calculated and experimental electronic circular dichroism(ECD)*** 1 was a racemic mixture and successfully resolved into the anticipated enantiomers via chiral-phase *** 3 demonstrated moderate inhibitory activity against human carboxylesterase 2A1(hCES2Al)with an IC_(50) value of 7.28±0.94 μmol·L^(-1).

关键词： Paeonia lactiflora Neolignan Lignan Human carboxylesterase 2A1

GPR37调节巨噬细胞的吞噬功能并参与炎症痛的消退

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中国疼痛医学杂志 2018年第11期24卷 813-814页

作者： bang s xie yk zhang zj 刘文涛(译) 高永静(校) 不详南京医科大学基础医学院南通大学航海医学所

炎症致痛的机制已经得到广泛的证明,但是疼痛的消退原理仍未完全阐明。本研究发现,巨噬细胞表达的GPR37可能是炎症痛消退的关键因素。NPD1 (Neuroprotectin D1)及TX14可以增加GPR37转染的HEK293细胞内Ca2+水平。NPD1和TX14可激活GPR37... 详细信息

炎症致痛的机制已经得到广泛的证明,但是疼痛的消退原理仍未完全阐明。本研究发现,巨噬细胞表达的GPR37可能是炎症痛消退的关键因素。NPD1 (Neuroprotectin D1)及TX14可以增加GPR37转染的HEK293细胞内Ca2+水平。NPD1和TX14可激活GPR37触发巨噬细胞通过钙信号吞噬酵母聚糖颗粒。本研究通过在体实验发现小鼠后足注射pH敏感性酵母聚糖颗粒不仅诱导炎症痛、中性粒细胞和巨噬细胞的浸润,而且会导致巨噬细胞GPR37上调。巨噬细胞吞噬酵母聚糖颗粒和中性粒细胞,进而导致炎症的消退。缺失GPR37的小鼠表现出巨噬细胞吞噬功能障碍和炎症消退的延迟。而在细胞水平上,缺失GPR37基因的巨噬细胞表现出抗炎和促炎细胞因子的失调。本研究揭示了GPR37在调节巨噬细胞吞噬功能和炎症痛消退方面的作用。

关键词：巨噬细胞吞噬功能炎症消退炎症痛调节中性粒细胞 HEK293 酵母聚糖促炎细胞因子