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人成纤维细胞样细胞株产生的肿瘤细胞生长抑制因子的发现和证明

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中国医学科学院学报 1987年第1期9卷 1-6+79-80页

作者：吴克复 Pope jh Ellem KAO 中国医学科学院血液学研究所澳大利亚昆士兰医学研究所(QIMR) 澳大利亚昆士兰医学研究所(QIMR) 天津

在混合培养体系中,部份人成纤维细胞样细胞株,尤其人胚肌成纤维细胞株能抑制被测的大多数Burkitt淋巴瘤(BL)细胞系和人黑色素瘤(MM)细胞系;但不能抑制类淋巴母细胞系(LCL)和大多数人白血病细胞系。此效应具时间和细胞浓度依赖性。将被... 详细信息

在混合培养体系中,部份人成纤维细胞样细胞株,尤其人胚肌成纤维细胞株能抑制被测的大多数Burkitt淋巴瘤(BL)细胞系和人黑色素瘤(MM)细胞系;但不能抑制类淋巴母细胞系(LCL)和大多数人白血病细胞系。此效应具时间和细胞浓度依赖性。将被抑制的肿瘤细胞从混合培养体系中取出,洗涤后再悬于新鲜培养液中,肿瘤细胞生长有一定程度恢复。用成纤维细胞样细胞的洗液也可证明其抑制活性,它对链霉蛋白酶敏感。

关键词：生长抑制因子成纤维细胞细胞因子 Burkitt 淋巴瘤黑色素瘤

Van der Waerden 所建立的代数几何基础

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数学译林 1995年第4期14卷 280-287页

作者： Boer.,jh 胥鸣伟

Influence of pH on the Formation, Composition and Protectiveness of Fluoride Conversion Film Deposited on AZ31 Magnesium Alloy in KF Solution

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Acta Metallurgica Sinica(English Letters) 2023年第9期36卷 1397-1408页

作者： Liping Wu Chen Liu Jie Wei Junhua Dong lin Zhao Chao Li Wei Ke Yiqing Chen Changgang Wang Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China State Key Laboratory of Metal Material for Marine Equipment and Application Anshan114009China

In deaerated 0.1 M KF solution at pH 5, pH 7.5 and pH 9, fluoride films were deposited on AZ31 magnesium (Mg) alloy at − 1.4 V vs saturated calomel electrode (SCE). The morphology, phase composition, elemental and compositional depth distribution of different fluoride films and their influences on the corrosion resistance of AZ31 Mg alloy were explored in detail. The results indicated that the films deposited at weak acidic and nearly neutral pH consisted of two layers with amorphous Mg(OH)_(2) and MgF_(2) as the inner layer, and Mg(OH)_(2), MgF_(2) and KMgF_(3) crystals the outer layer. The film deposited at alkaline pH was a monolayer structure consisting of amorphous Mg(OH)_(2) as the major constitute and MgF_(2) as the minor constitute. The protectiveness of fluoride film was intimately related to its composition and structure. The content and crystal regularity of KMgF_(3) were the two main factors influencing the protectiveness of fluoride film. The fluoride film deposited at pH 7.5 offered the best protection to AZ31 Mg alloy.

关键词： Magnesium alloy Potentiostatic deposition Fluoride film KF solution

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急性淋巴细胞白血病骨髓移植的指征

国外医学（输血及血液学分册） 1991年第5期14卷 306-307页

作者： Ramsay NKC Kersey jh 谢波

由于化疗对许多急性淋巴细胞白血病(ALL)患者有良好的疗效,骨髓移植通常仅用于该病的高危患者(包括化疗失败者),本文主要论述ALL治疗的选择及其结果,并讨论HLA匹配的相关或无关骨髓移植和自体骨髓移植的选择。采用同仲异基因骨髓移植于... 详细信息

由于化疗对许多急性淋巴细胞白血病(ALL)患者有良好的疗效,骨髓移植通常仅用于该病的高危患者(包括化疗失败者),本文主要论述ALL治疗的选择及其结果,并讨论HLA匹配的相关或无关骨髓移植和自体骨髓移植的选择。采用同仲异基因骨髓移植于高危ALL,存活最长者是那些接受相匹配同胞骨髓的病人,特别是预处理用环磷酰胺加全身照射(TBI)者。本移植方法的局限在于符合条件的供髓者较少,只有不到1/3的患者具有相匹配的同胞供髓者。

关键词：白血病骨髓移植

维普期刊数据库

Novel 3D Printed Modular Hemipelvic Prosthesis for Successful Hemipelvic Arthroplasty： A Case Study

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Journal of Bionic Engineering 2018年第6期15卷 1067-1074页

作者： Xin Zhao Jianlin Xiao Yu Sun Zhe Zhu Meng Xu XiaonanWang Feifei lin Yanbing Wang Jincheng Wang Orthopedic Department the Second Hospital of Jilin University Changchun 130041 China Orthopedic Department China-Japan Union Hospital of Jilin University Changchun 130033 China

In this study, in order to prevent the failure of hemipelvic arthroplasty using a patient-specific Computer-Aided Design （CAD） and Additive Manufacturing （AM） approach, a new design for modular hemipelvic prosthesis was developed. Moreover, the biomechanical properties of the new design were determined. The 3D printed pelvic prosthesis with a sacrum portion that completely matches the back surface of the patient＇s sacrum offers more potential for bone ingrowth between the host bone and prosthesis. The new approach integrated the capabilities of digital medical imaging techniques, CAD and metal AM to realize a modular hemipelvic prosthesis. The patient＇s pelvic Digital Imaging and Communication in Medicine （DICOM） data were imported into Mimics software to construct a digital representative patient model for design of the prosthesis. A physical model was obtained using a Stereolithography （SLA） 3D printer for preoperative planning. The final customized implant was designed by using UG NX 10.0 software. Then a surgically modular hemipelvic prosthesis was fabricated from the Ti6Al4V titanium alloy by electron beam melting technology. The operation was performed according to the preoperative planning. The outcome of the operation was good at the 6-month follow-up. Also, the stress distribution and the relative micromotion revealed positive results based on a finite element model built to detect prosthesis stability. The 3D printed modular hemipelvic prosthesis provided good resolution for the failure of hemipelvic arthroplasty. Personal customization will be important in future surgeries aiming at improving the anatomy and function of the implant.

关键词： 3D printing hemipelvic prosthesis 3D reconstruction rapid prototype bionic prosthesis design

Diagnosis and management of cystic duct leakage after laparoscopic cholecystectomy, report of 3 cases

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第二军医大学学报 2005年第10期26卷 1143-1143页

作者： Li jh Liu HT Minimally Invasive Surgery Center Changhai Hospital Second Military Medical University Shanghai 200433China

Ionic Liquid-Stabilized Single-Atom Rh Catalyst Against Leaching

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CCS Chemistry 2021年第10期3卷 1814-1822页

作者： Shipeng Ding Max jhülsey Hua An Qian He Hiroyuki Asakura Min Gao Jun-ya Hasegawa Tsunehiro Tanaka Ning Yan Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117585 Joint School of the National University of Singapore and Tianjin University International Campus of Tianjin UniversityBinhai New CityFuzhou 350207 Department of Materials Science and Engineering National University of SingaporeSingapore 117575 Department of Molecular Engineering Graduate School of EngineeringJapan and Elements Strategy Initiative for Catalysts and Batteries(ESICB)Kyoto UniversityKyoto 615-8510615-8245 Institute for Catalysis Hokkaido UniversitySapporo 001-0021

Single-atom catalysts(SACs)are promising in some reactions typically promoted by homogeneous ***,the leaching of active species from the support in liquid-phase reactions hinders their potential ***,taking the hydroformylation reaction as an example,we report ionic liquid(IL)-induced stabilization of single Rh atoms against *** the ILs examined.

关键词： single-atom catalysts electrostatic stab ilization ionic liquid leaching

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萘啶酸类抗菌剂的定量构效关系(中)

国外医药（抗生素分册） 1992年第1期13卷 19-28,36页

作者： Block jh 苗华郭惠元

四、结果和讨论(一)A 组只有6位变化的1-乙基-7-哌嗪基系列化合物 A34、A37、A39和 A41～A45的生物活性结果表明氟取代活性较好。哌嗪 NH 的氢(A34)被烷基(A36、A68～A72、A79)或酰基(A73～A75)取代后,抗革兰氏阴性菌特别是绿脓杆菌的... 详细信息

四、结果和讨论(一)A 组只有6位变化的1-乙基-7-哌嗪基系列化合物 A34、A37、A39和 A41～A45的生物活性结果表明氟取代活性较好。哌嗪 NH 的氢(A34)被烷基(A36、A68～A72、A79)或酰基(A73～A75)取代后,抗革兰氏阴性菌特别是绿脓杆菌的活性降低。A34中1-乙基被2-

关键词：萘啶酸类抗菌剂定量构效

维普期刊数据库

Improvement of the dissolution rate of silymarin by means of solid dispersions

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第二军医大学学报 2005年第2期26卷 229-229页

作者： Li FQ Hu jh Department of Pharmaceutical Sciences Changhai Hospital Second Military Medical University Shanghai 200433 China

Solid dispersions of silymarin were prepared by the fusion method with the intention of improving the dissolution properties of silymarin. Polyethylene glycol 6000 (PEG 6000) was used as the inert hydrophilic matrix. The dissolution studies of the solid dispersions were performed in vitro. And the results obtained showed that the dissolution rate of silymarin was considerably improved when formulated in solid dispersions with PEG 6000 as compared to original drug, and the increased dissolution rate might be favorable for further oral absorption.

关键词： solid dispersions dissolution rate fusion method in vitro