检索结果-南通市图书馆

Matter and Radiation at Extremes 2024年第3期9卷 57-64页

作者： Zhiyu Zhang Yang Zhao Xiaoying Han liling li Bo Qing lifei Hou Yulong li YuXue Zhang Huan Zhang Xiangming liu Bo Deng Gang Xiong Min Lv Tuo Zhu Chengwu Huang Tianming Song Yan Zhao Yingjie li Lu Zhang Xufei Xie Jiyan Zhang Jiamin Yang Laser Fusion Research Center China Academy of Engineering PhysicsMianyang 621900China National Key Laboratory of Plasma Physcis Mianyang 621900China Institute of Applied Physics and Computational Mathematics Beijing 100088China

A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material is proposed.A specially designed symmetrical triple-cavity gold Hohlraum is used to create approximately constant and near-equilibrium uniform radiation with a peak temperature of 160 *** incident flux at the secondary cavity waist is obtained from flux balance analysis and from the shock velocity of a standard *** results agree well owing to the symmetrical radiation in the secondary cavity.A self-consistent and precise time-dependent radiative albedo is deduced from the reliable reemission flux and the incident flux,and the result from the shock velocity is found to have a smaller uncertainty than that from the multi-angle flux balance analysis,and also to agree well with the result of a simulation using the HYADES opacity.

关键词： precise cavity radiative

基于动态血糖监测的个体化指导方案用于妊娠期糖尿病孕妇中的效果观察

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国医药指南 2024年第18期22卷 44-46页

作者：李丽玲厦门大学附属中山医院产科厦门361000

目的探究基于动态血糖监测的个体化指导方案用于妊娠期糖尿病孕妇中的效果。方法将我院2022年1月至2023年8月收治的80例孕妇进行研究,分为两组(试验组与对照组),开展不同血糖指导,对比两组的护理满意度、血糖相关指标、知信行与应对方... 详细信息

目的探究基于动态血糖监测的个体化指导方案用于妊娠期糖尿病孕妇中的效果。方法将我院2022年1月至2023年8月收治的80例孕妇进行研究,分为两组(试验组与对照组),开展不同血糖指导,对比两组的护理满意度、血糖相关指标、知信行与应对方式。结果试验组护理满意度与依从性高于对照组;试验组血糖相关指标较之对照组差异显著(P<0.05);试验组知信行评分与对照组比较,差异较大,且差异有统计学意义(P<0.05);试验组应对方式较之对照组更具优势(P<0.05)。结论妊娠期糖尿病孕妇用到基于动态血糖监测的个体化指导方案,其血糖相关指标得到显著调整,且提升患者积极应对能力,改善其知信行与护理满意度,值得临床广泛推荐。

关键词：基于动态血糖监测的个体化指导方案妊娠期糖尿病孕妇护理满意度应对方式

Tamping the movement of the laser absorption cutoff position using gold foam hohlraum

在线全文

学校读者我要写书评

暂无评论

Plasma Science and Technology 2024年第5期26卷 56-61页

作者：张璐李丽灵林稚伟董云松景龙飞郑建华况龙钰黎航郑金华张继彦宋天明张志宇赵阳牛高杨冬杨家敏丁永坤 Research Center of Laser Fusion China Academy of Engineering PhysicsMianyang 621900People’s Republic of China Institute of Applied Physics and Computational Mathematics Beijing 100088People’s Republic of China

In indirect-driven laser fusion experiments,the movement of the laser absorption layer will distort the radiation uniformity on the *** gold foam has advantages in symmetry control and lowering wall plasma blowoff when used in an inertial confinement fusion(ICF)*** work investigates the motion of the laser absorption cutoff position using lowdensity foam gold *** is found that the motion of the laser absorption cutoff position can be significantly mitigated through optimal initial low density,tailored to a specific laser *** a short square laser pulse,the laser absorption cutoff position remains almost stationary at an initial density of approximately 0.6 g cm^(-3).For a long-shaped laser pulse,the minimal motion of the laser absorption cutoff position is observed at an initial density of about 0.1 g cm^(-3).This approach allows for the adjustment of the symmetry of the hohlraum radiation *** insights gained from this study serve as a crucial reference for optimizing the hohlraum wall density.

关键词： hohlraum symmetry laser absorption plasma blowoff gold foam

1例重度支气管肺发育不良早产儿从医院到家庭过渡期的护理

在线全文

学校读者我要写书评

暂无评论

中华护理杂志 2024年第2期59卷 210-214页

作者：钱丽清陆晓燕李丽玲蒋思远胡晓静复旦大学附属儿科医院新生儿重症监护室上海市201102 复旦大学附属儿科医院护理部上海市201102

总结1例重度Ⅱ型支气管肺发育不良(bronchopulmonary dysplasia,BPD)极低出生体重早产儿从住院到家庭过渡期的护理。该患儿由BPD专病护士全程进行一对一护理,其从医院到家庭过渡期的护理要点:实施气管切开及机械通气护理,确保患儿血氧... 详细信息

总结1例重度Ⅱ型支气管肺发育不良(bronchopulmonary dysplasia,BPD)极低出生体重早产儿从住院到家庭过渡期的护理。该患儿由BPD专病护士全程进行一对一护理,其从医院到家庭过渡期的护理要点:实施气管切开及机械通气护理,确保患儿血氧饱和度稳定;提供营养支持,改善患儿的营养状况;实施循序渐进的康复训练,改善患儿的神经运动发育;实施家庭参与式护理,促进患儿的主要照护者掌握照护知识与技能;开展多学科团队个体化出院随访,提高患儿居家护理质量。患儿住院106 d后顺利带气管切开套管出院,2岁6个月时行气管切开闭合术,术后患儿可自主呼吸,无呼吸困难症状,回归正常家庭生活。

关键词：支气管肺发育不良婴儿极低出生体重早产儿过渡期新生儿护理

从卫气的生成与输布探讨化疗后白细胞减少症的中医治疗策略

在线全文

学校读者我要写书评

暂无评论

中医杂志 2024年第1期65卷 113-118页

作者：毕盛吴胤文李丽玲张伟娜黄金昶北京中医大学附属第三医院北京市100029

通过分析卫气与白细胞在功能、发挥作用部位、昼夜节律方面的相似性,提出白细胞减少症的中医病机为卫气不足。基于对历代经典中卫气生成输布相关论述的梳理,认为下焦元气为卫气之源,中焦水谷之气充实卫气,上焦输布卫气至周身。故而临床... 详细信息

通过分析卫气与白细胞在功能、发挥作用部位、昼夜节律方面的相似性,提出白细胞减少症的中医病机为卫气不足。基于对历代经典中卫气生成输布相关论述的梳理,认为下焦元气为卫气之源,中焦水谷之气充实卫气,上焦输布卫气至周身。故而临床中医治疗化疗后白细胞减少症可以龟鹿二仙胶、右归丸等补肾填精,结合艾灸关元、气海等穴位,补下焦元气以实卫气之源;以归脾汤、补中益气汤、参苓白术散、四君子汤等健脾益气,结合艾灸中脘、足三里等穴位,运中焦脾胃以充实卫气;以桂枝汤加减调和营卫,结合艾灸大椎、肺俞等穴位或刮痧,通上焦腠理以促进卫气输布。从卫气生成输布的全过程考虑,灵活选择内治法与外治法相结合,以期为肿瘤患者白细胞减少症的治疗提供思路。

关键词：白细胞减少症卫气化疗恶性肿瘤

在线全文

学校读者我要写书评

暂无评论

极低出生体重儿住院期间经口喂养方案的构建

护理学杂志 2024年第8期39卷 39-44,53页

作者：王源裘梦凡杨童玲李丽玲万凡胡晓静复旦大学附属儿科医院新生儿科上海201102 复旦大学护理学院复旦大学附属儿科医院护理部上海201102

目的构建极低出生体重儿住院期间经口喂养方案,以规范经口喂养,推进其经口喂养进程、促进生长发育。方法以统合发展理论为指导,通过循证方法学总结极低出生体重儿经口喂养的最佳证据,经过研究小组讨论形成极低出生体重儿住院期间经口喂... 详细信息

目的构建极低出生体重儿住院期间经口喂养方案,以规范经口喂养,推进其经口喂养进程、促进生长发育。方法以统合发展理论为指导,通过循证方法学总结极低出生体重儿经口喂养的最佳证据,经过研究小组讨论形成极低出生体重儿住院期间经口喂养方案初稿,进行2次专家论证会议讨论,根据专家意见结合临床实践,对方案初稿进行修订完善。结果形成包括入院后-经口喂养准备、微量经口喂养(母乳滴注喂养、个性化奶嘴内母乳滴喂)、每12小时尝试经口奶瓶喂养1次、每6小时尝试经口奶瓶喂养1次、每次喂养尝试经口奶瓶喂养、母乳亲喂6个环节的极低出生体重儿住院期间经口喂养方案。结论基于循证的极低出生体重儿住院期间经口喂养方案具有较好的科学性和临床适宜性,可为临床开展有效规范的经口喂养提供参考。

关键词：极低出生体重儿母乳滴注喂养经口喂养奶瓶喂养母乳亲喂循证护理

Glutamicibacter nicotianae AT6:A new strain for the efficient biodegradation of tilmicosin

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第8期142卷 182-192页

作者： Huijuan li Hao Zhou liling Fan Long Meng Yanyun Zhao Lanmei Zhao Bo Wang College of Chemical and Biological Engineering Shandong University of Science and TechnologyQingdao 266590China College of Chemistry and Chemical Engineering Heze UniversityHeze 274015China College of Safety and Environmental Engineering Shandong University of Science and TechnologyQingdao 266590China

The degradation of tilmicosin(TLM),a semi-synthetic 16-membered macrolide antibiotic,has been receiving increasing ***,there are three tilmicosin degradation methods,and among them microbial degradation is considered the best due to its high efficiency,eco-friendliness,and low ***,we found a new strain,Glutamicibacter nicotianae ***6,capable of degrading high-concentration TLM at 100 mg/L with a 97%removal *** role of tryptone was as well investigated,and the results revealed that the loading of tryptone had a significant influence on TLM *** toxicity assessment indicated that strain AT6 could efficiently convert TLM into less-toxic *** on the identified intermediates,the degradation of TLM by AT6 processing through two distinct pathways was then proposed.

关键词： Tilmicosin Glutamicibacter nicotianae Biodegradation Degradation pathway Pharmaceutical wastewater

Assessment of cheese sign and its association with vascular risk factors:Data from PUMCH dementia cohort

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第7期137卷 830-836页

作者： Xinying Huang Bo Hou Jie Wang Jie li li Shang Chenhui Mao liling Dong Caiyan liu Feng Feng Jing Gao Bin Peng Department of Neurology State Key Laboratory of Complex Severe and Rare DiseasePeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Radiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Background:In the clinic,practitioners encounter many patients with an abnormal pattern of dense punctate magnetic resonance imaging(MRI)signal in the basal ganglia,a phenomenon known as"cheese sign".This sign is reported as common in cerebrovascular diseases,dementia,and old ***,cheese sign has been speculated to consist of dense perivascular space(PVS).This study aimed to assess the lesion types of cheese sign and analyze the correlation between this sign and vascular disease risk ***:A total of 812 patients from Peking Union Medical College Hospital(PUMCH)dementia cohort were *** analyzed the relationship between cheese sign and vascular *** assessing cheese sign and defining its degree,the abnormal punctate signals were classified into basal ganglia hyperintensity(BGH),PVS,lacunae/infarctions and microbleeds,and counted *** type of lesion was rated on a four-level scale,and then the sum was calculated;this total was defined as the cheese sign *** and Age-Related White Matter Changes(ARWMC)scores were used to evaluate the paraventricular,deep,and subcortical gray/white matter ***:A total of 118 patients(14.5%)in this dementia cohort were found to have cheese ***(odds ratio[OR]:1.090,95%confidence interval[CI]:1.064-1.120,Plipidemia,and cheese *** main components of cheese sign were BGH,PVS,and lacunae/*** proportion of PVS increased with cheese sign ***:The risk factors for cheese sign were hypertension,age,and *** sign consists of BGH,PVS,and lacunae/infarction.

关键词： Dementia Cerebrovascular disease Cheese sign Dense punctate lesions Basal ganglia Risk factor White matter

Collision-avoidance path planning for multi-ship encounters considering ship manoeuvrability and COLREGs

在线全文

学校读者我要写书评

暂无评论

Transportation Safety and Environment 2021年第2期3卷 103-113页

作者： Yixiong He Zhaoran li Junmin Mou Weixuan Hu liling li Bing Wang School of Navigation Wuhan University of TechnologyWuhanHubei 430063China Hubei Key Laboratory of Inland Shipping Technology WuhanHubei 430063China Wuhan Technical College of Communications WuhanHubei 430060China

Ship collision prevention has always been a hot topic of research for navigation ***,autonomous ships have gained much attention as a means of solving collision problems by machine control with a collision-avoidance *** important question is how to determine optimal path planning for autonomous *** paper proposes a path-planning method of collision avoidance for multi-ship encounters that is easy to realize for autonomous *** ship course-control system uses fuzzy adaptive proportion-integral-derivative(PID)control to achieve real-time control of the *** automatic course-altering process of the ship is predicted by combining the ship-motion model and PID *** to the COLREGs,ships should take different actions in different encounter ***,a scene-identification model is established to identify these *** avoid all the TSs,the applicable course-altering range of the OS is obtained by using the improved velocity obstacle *** optimal path of collision avoidance can be determined from an applicable course-altering range combined with a scene-identification ***,the path planning of collision avoidance is realized in the multi-ship environment,and the simulation results show a good *** method conforms to navigation practice and provides an effective method for the study of collision avoidance.

关键词： autonomous ships collision avoidance path planning ship manoeuvrability COLREGs

M6PR interacts with the HA2 subunit of influenza A virus to facilitate the fusion of viral and endosomal membranes

在线全文

学校读者我要写书评

暂无评论

Science China(life Sciences) 2024年第3期67卷 579-595页

作者： Yuzhen Hu li Jiang Guangwen Wang Yangming Song Zhibo Shan Xuyuan Wang Guohua Deng Jianzhong Shi Guobin Tian Xianying Zeng liling liu Hualan Chen Chengjun li State Key Laboratory for Animal Disease Control and Prevention Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069China

Influenza A virus(IAV) commandeers numerous host cellular factors for successful replication. However, very few host factors have been revealed to be involved in the fusion of viral envelope and late endosomal membranes. In this study, we identified cation-dependent mannose-6-phosphate receptor(M6PR) as a crucial host factor for the replication of IAV. We found that siRNA knockdown of M6PR expression significantly reduced the growth titers of different subtypes of IAV, and that the inhibitory effect of M6PR siRNA treatment on IAV growth was overcome by the complement of exogenously expressed M6PR. When A549 cells were treated with siRNA targeting M6PR,the nuclear accumulation of viral nucleoprotein(NP) was dramatically inhibited at early timepoints post-infection, indicating that M6PR engages in the early stage of the IAV replication cycle. By investigating the role of M6PR in the individual entry and post-entry steps of IAV replication, we found that the downregulation of M6PR expression had no effect on attachment, internalization, early endosome trafficking,or late endosome acidification. However, we found that M6PR expression was critical for the fusion of viral envelope and late endosomal membranes. Of note, M6PR interacted with the hemagglutinin(HA) protein of IAV, and further studies showed that the lumenal domain of M6PR and the ectodomain of HA2 mediated the interaction and directly promoted the fusion of the viral and late endosomal membranes,thereby facilitating IAV replication. Together, our findings highlight the importance of the M6PR–HA interaction in the fusion of viral and late endosomal membranes during IAV replication.

关键词： influenza A virus M6PR HA membrane fusion late endosome