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current Zoology 2011年第5期57卷 648-654页

作者： jim GRAHAM catherine JARNEVIcH Nick YOUNG Greg NEWMAN Thomas STOHLGREN Natural Resource Ecology Laboratory Colorado State University Fort Collins CO 80523-1499 USA Fort collins Science center U.S. Geological Survey 2150 Centre Ave. Building C Fort Collins CO 80526 USA

Habitat suitability models have been used to predict the present and future potential distribution of a variety of spe- cies. Eurasian tree sparrows Passer montanus, native to Eurasia, have established populations in other parts of the world. In North America, their current distribution is limited to a relatively small region around its original introduction to St. Louis, Missouri. We combined data from the Global Biodiversity Information Facility with current and future climate data to create habitat suitability models using Maxent for this species. Under projected climate change scenarios, our models show that the distribution and range of the Eurasian tree sparrow could increase as far as the Pacific Northwest and Newfoundland. This is potentially important in-formation for prioritizing the management and control of this non-native species [current Zoology 57 （5）： 648--654, 2011].

关键词： Eurasian tree sparrows Passer montanus Maxent climate change Distribution model

Monodisperse ZnO Solid Spheres by an Assisted Structure Directing Agent-Hydrothermal Method

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World Journal of condensed Matter Physics 2015年第4期5卷 332-338页

作者： S. López-Romero M. J. Quiroz jim.nez Departamento de Materia condensada y criogenia Instituto de Investigaciones en Materiales Universidad Nacional Autónoma de México México DF México

Monodisperse ZnO solid spheres nanostructures were synthesized and deposited on Si (100) silicon substrates by the hexamethylenetetramine (HMTA)-assisted hydrothermal method at high temperature (200°c). In this case the HMTA is used as structure directing agent (SDA) to growth of the ZnO solid spheres. The source material used was zinc nitrate hexahydrate under a chemical reaction of hydrolysis-condensation of the Zn2+ salt aqueous solution. The structure and morphology of the ZnO solid spheres were studied by means of X-ray diffraction (XRD) and scanning electron microscopy (SEM) techniques. Furthermore, the photoluminescence (PL) of the ZnO solid spheres was measured to optical characterization of the product. The remarkable influence of the HMTA as structure directing agent and the reaction temperature to the formation of the solid spheres nanostructures is demonstrated.

关键词： Zinc Oxide Solid Spheres Nanostructures Silicon Substrate Hydrothermal Method

Pretreatment inflammatory indices predict Bevacizumab response in recurrent Glioma

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cancer Drug Resistance 2020年第3期3卷 623-635页

作者： Alicia Martínez-González Raquel cabrera Marta Lloret Pedro c.Lara Department de Matemáticas Universidad de Castilla-La ManchaETSI IndustrialesAvdaCiudad Real 13071Spain. Oncología Radioterápica Hospital Universitario de Gran canaria Dr Negrin Barranco de la Ballena s/nLas Palmas de Gran CanariaLas Palmas 35010Spain. Facultad de ciencias de la Salud Universidad de Las Palmas de Gran CanariaPaseo de Blas Cabrera Felipes/nLas Palmas de Gran CanariaLas Palmas 35016Spain. Fundación canaria del Instituto canario de Investigación del cáncer Avda de la Trinidad 61 Torre Agustín Arevalo 7 planta La LagunaSanta Cruz de Tenerife 38204Spain. San Roque University Hospitals Dolores de la Rocha5Las Palmas de Gran CanariaLas Palmas 35001Spain. Fernando Pessoa canarias University Dolores dela Rocha 14Las Palmas de Gran CanariaLas Palmas 35016Spain.

Aim:It remains unclear what the best therapeutic option for recurrent glioma patients after Stupp treatment ***(BVZ)is commonly administered in progression,but it appears that only some patients *** would be useful to find biomarkers that determine beforehand who these patients ***:The protocol included 31 high-risk progressing glioma patients after Stupp treatment who received BVZ 5-10 mg/kg every 14 days and temozolomide(3-19 cycles,150-200 mg five days each 28-day cycle)during a mean of eight cycles of BVZ or until tumor progression or unacceptable *** analyzed the clinical outcome values of inflammatory indices measured before BVZ ***:Lymphocyte level before BVZ administration was the best independent predictor of overall survival(HR=0.34;95%cI:0.145-0.81;P=0.015).The area under the receiver operating characteristic(ROc)curve was 0.823,with 1.645 being the optimal cut-off value,and 0.80 and 0.85 the sensitivity and specificity values,*** and non-responder survival curves were also significantly different,considering the first and second tertiles as cut-off *** number of BVZ cycles was not related to *** neutrophil platelet levels,platelet-to-lymphocyte ratio(PLR),and neutrophil-to-lymphocyte ratio(NLR)did not have independent predictive *** variables were not correlated with each ***,patients with high NLR and PLR simultaneously(double positive PLR-NLR)showed a worse clinical outcome than the rest(P=0.043).conclusion:Pretreatment lymphocyte levels and double positive PLR-NLR could be used as non-invasive hematological prognostic markers for recurrent gliomas treated with bevacizumab.A close relationship emerged between inflammation and angiogenesis.

关键词： Recurrent glioma bevacizumab predictive biomarker inflammatory indices lymphocytes

Influence of Surfactant and Salt concentration on the Rheological Properties of Three Different Microstructures of Associative Polyelectrolytes Obtained by Solution Polymerization

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Journal of Modern Physics 2014年第14期5卷 1387-1396页

作者： Areli I. Velazquez-Garcia Gregorio cadenas-Pliego claudia c. Rivera-Vallejo Enrique J. jim.nez-Regalado centro de Investigación en Química Aplicada (cIQA) Saltillo México

The rheological properties of three different microstructures of hydrophobically modified alkalisoluble polymers (telechelic, multisticker and combined) in the presence of various concentrations of anionic surfactant and salt (Nacl) were investigated. Associative polymers containing both ionic sites and small number of hydrophobic groups were obtained, and their thickening properties in aqueous solutions, were investigated. Solution polymerization was used for obtaining the different polymers. Relationships between hydrophobe, sodium dodecyl sulfate (SDS) and Nacl concentration are proposed. Owing to the competition between attractive hydrophobic interaction and repulsive electrostatic interactions, such hydrophobically modified polymers exhibit various rheological behaviors in aqueous solutions, depending on microstructure of polyelectrolyte, SDS and Nacl concentrations.

关键词： Polymerization Associative Polyelectrolyte Rheology Surfactant and Salt concentration

Phenolic metabolism and molecular mass distribution of polysaccharides in cellulose-deficient maize cells

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Journal of Integrative Plant Biology 2017年第7期59卷 475-495页

作者： María de castro Romina Martínez-Rubio José L.Acebes Antonio Encina Stephen c.Fry Penélope García-Angulo área de Fisiología Vegetal.Dpto.Ingenieríay ciencias Agrarias.Facultad de Biologíay ciencias Ambientales.Universidad de León The Edinburgh cell Wall Group Institute of Molecular Plant Sciences School of Biological Sciences Daniel Rutherford BuildingThe King's Buildings

As a consequence of the habituation to low levels of dichlobenil （DcB）, cultured maize cells presented an altered hemicellulose cell fate with a lower proportion of strongly wall-bound hemicelluloses and an increase in soluble extracellular polymers released into the culture medium. The aim of this study was to investigate the relative molecular mass distributions of polysaccharides as well as phenolic metabolism in cells habituated to low levels of DcB （1.5 μM）. Generally, cell wall bound hemicelluloses and sloughed polymers from habituated cells were more homogeneously sized and had a lower weight-average relative molecular mass. In addition, polysaccharides underwent massive cross-linking after being secreted into the cell wall, but this cross-linking was less pronounced in habituated cells than in non-habituated ones. However, when relativized, ferulic acid and p-coumaric acid contents were higher in this habituated cell line. Feasibly, cells habituated to low levels of DcB synthesized molecules with a lower weight-average relative molecular mass, although cross-linked, as a part of their strategy to compensate for the lack of cellulose.

关键词： Phenolic metabolism and molecular mass distribution of polysaccharides in cellulose-deficient maize cells were for

A stable anthraquinone-derivative cathode to develop sodium metal batteries: The role of ammoniates as electrolytes

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Journal of Energy chemistry 2023年第2期77卷 572-580,I0015页

作者： Débora Ruiz-Martínez José M.Orts Roberto Gómez Departament de Química Física i Institut Universitari d’Electroquímica Universitat d’AlacantApartat 99Alicante E-03080Spain

Rechargeable sodium metal batteries constitute a cost-effective option for energy storage although sodium shows some drawbacks in terms of reactivity with organic solvents and dendritic *** we demonstrate that an organic dye,indanthrone blue,behaves as an efficient cathode material for the development of secondary sodium metal batteries when combined with novel inorganic *** electrolytes are ammonia solvates,known as liquid ammoniates,which can be formulated as NaI·3.3NH_(3) and NaBF_(4)·2.5NH_(3).They impart excellent stability to sodium metal,and they favor sodium non-dendritic growth linked to their exceedingly high sodium ion *** advantage is complemented by a high specific *** battery described here can last hundreds of cycles at 10 c while keeping a coulombic efficiency of 99%from the first *** of the high capacity of the cathode and the superior physicochemical properties of the electrolytes,the battery can reach a specific energy value as high as 210 W h kgIB^(-1),and a high specific power of 2.2 kW kgIB^(-1),even at below room temperature(4℃).Importantly,the battery is based on abundant and cost-effective materials,bearing promise for its application in large-scale energy storage.

关键词： Sodium metal batteries Anthraquinone-based cathode Vat dye Indanthrone blue Inorganic electrolytes Liquid ammoniates

Recent progress on bimetallic Nico and coFe based electrocatalysts for alkaline oxygen evolution reaction: A review

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Journal of Energy chemistry 2022年第4期31卷 101-137页

作者： Gebrehiwet Abrham Gebreslase Maria Victoria Martínez-Huerta Maria Jesus Lázaro Instituto de carboquímica CSIC.Miguel LuesmaCastán 450018ZaragozaSpain Instituto de catálisis y Petroleoquímica CSIC.Marie Curie 228049MadridSpain

The deployment of hydrogen as an energy carrier is found to be a vital alternative fuel for the future. It is expected that water electrolysis, powered by renewable energy sources, be able to scale-up hydrogen production. However, the reaction kinetic of oxygen evolution reaction(OER) is a sluggish process, which predominantly limits the efficiency of water electrolysis. This review recapitulates the recent progress and efforts made in the design and development of two selected earth-abundant bimetallic electrocatalysts(Ni co and co Fe) for alkaline OER. Each bimetal electrocatalyst is thoroughly outlined and discussed in five sub-sections, including bimetal(oxy) hydroxides, Layered double hydroxides(LDHs) structures,oxides, composites, alloy and nanostructured electrocatalysts, and assembled with ***, a brief introduction to an in situ/operando characterization techniques and advantages for monitoring the structure of the electrocatalysts is provided. Finally, a summary outlining the challenges and conceivable approaches to advance OER performance is highlighted and discussed.

关键词： Water electrolysis Oxygen evolution reaction Bimetallic electrocatalyst Nickel cobalt and iron

Raman spectroscopy for detection of imatinib in plasma: A proof of concept

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Journal of Innovative Optical Health Sciences 2015年第5期8卷 56-66页

作者： Sanhita Rath Aditi Sahu Vikram Gota P.G.Martínez-Torres J.L.Pichardo-Molina c.Murali Krishna Department of clinical Pharmacology ACTREC Tata Memorial CenterKharghar Navi Mumbai 410210 India chilakapati Lab ACTRECTata Memorial Center KhargharNavi Mumbai 410210 India Instituto de Fisica y Matematicas Universidad Michoacana de San Nicolas de Hidalgo Edificio c-3 Ciudad Universitaria CP.58040 MoreliaMichoacanMexico centro de Investigaciones enOptica Ac c.P.37#150 Leon Gto.Mexico

Imatinib is the standard first line treatment for chronic myeloid leukemia(cML).Owing to doserelated toxicities of Imatinib such as neutropenia,there is scope for treatment optimization through therapeutic drug monitoring(TDM).Trough concentration of 1g/mL is considered the therapeutic *** methods for the detection of Imatinib in plasma are limited by long read out time and expensive ***,Raman spectroscopy was explored as a rapid and objective tool for monitoring Imatinib *** approaches:conventional Raman spectroscopy(cRS),Drop coating deposition Raman(DcDR)spectroscopy and surface-enhanced Raman spectroscopy(SERS)were employed to detect the required trough concentration of 1g/mL and *** of therapeutically relevant concentrations(1g/mL)using SERS and suitable nanoparticle substrates has been ***,rigorous validation using clinical samples is necessary to confirm the utility of this approach in routine clinical usage.

关键词： Therapeutic drug monitoring Raman spectroscopy Imatinib SERS DcDR chronic myeloid leukemia

Steatosis recovery after treatment with a balanced sunflower or olive oil-based diet: Involvement of perisinusoidal stellate cells

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World Journal of Gastroenterology 2005年第47期11卷 7480-7485页

作者： Raquel Hernández Esther Martínez-Lara Ana cauelo Ma Luisa del Moral Santos Blanco Eva Siles Ana jim.nez Juan ngel Pedrosa Ma ngeles Peinado Department of Experimental Biology University of JaénParaje Las Lagunillas s/nE-23071 JaénSpain

AIM： To analyze the relationship between perisinusoidal stellate cell （PSc） activation and the dietary fat quantity and composition in the treatment of hepatic steatosis. METHODS： Using an experimental rat model of steatosis based on the intake of a hyperlipidic diet （14% fat as olive oil or sunflower oil, HL-O and HL-S, respectively）, we analyzed the liver＇s capability of recovery after the treatment with a normal-lipidic diet （5% fat as olive oil or sunflower oil, NL-O and NL-S, respectively） by immunoo/tochemical and Western blot analysis of glial fibrillary acidic protein （GFAP） expression in PScs, collagen quantification and serum aminotransferase determination. RESULTS： The fatty infiltration in the steatotic livers decreased after the treatment with both NL diets, indicating liver recovery. This decrease was accompanied with a lower collagen deposition and aminotransferase level as well as changes in the PSc population that increased the GFAP expression. The above-mentioned effects were more pronounced in animals fed on NL-O based diet. cONcLUSION： Treatment with a balanced diet enriched in olive oil contributes to the liver recovery from a steatotic process. The PSc phenotype is a marker of this hepatic-recovery model.

关键词： PScs GFAP Steatosis collagen, Hyperlipidic diet Liver recovery Olive oil

Interactive effect of dietary vitamin E and inorganic mercury on growth performance and bioaccumulation of mercury in juvenile olive flounder, Paralichthys olivaceus treated with mercuric chloride

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Animal Nutrition 2017年第3期3卷 276-283页

作者： Mohammad Moniruzzaman Jun-Ho Lee Jin-Hyeok Lee Seonghun Won jim H.Damusaru Sungchul c.Bai Department of Marine Bio-materials and Aquaculture Feeds & Foods Nutrition Research CenterPukyong National University

A 6-week feeding trial was carried out to evaluate the effects of dietary vitamin E(DL-a-tocopheryl acetate, TA) on growth and mercury(Hg) accumulation in juvenile olive flounder(Paralichthys olivaceus)treated with mercuric chloride(Hgcl_2). Vitamin E and Hgcl_2 were added to the semi-purified basal *** semi-purified diets in a 2 × 3 factorial design were formulated to contain 2 levels of Hg(0 or 20 mg Hgcl_2/kg diet) and 3 levels of vitamin E(0, 100, or 200 mg TA/kg diet). Experimental fish(n = 360,9.99 ± 0.15 g) were randomly allocated into 30-L tanks at a density of 20 fish per tank with 3 replicates in each treatment and were fed twice a day. At the end of the feeding trial, dietary Hg depressed the growth performances in terms of weight gain(WG), specific growth rate(SGR), feed efficiency(FE) and protein efficiency ratio(PER) in fish, while fish fed the diets supplemented with vitamin E showed significant growth improvement in both presence and absence of Hgcl_2 in the diets(P cted in fish fed the experimental diets. Whole body compositions of fish such as lipid and moisture contents were influenced by dietary vitamin E supplementation. Total Hg contents of muscle, liver and kidney tissues were significantly reduced in fish fed diets supplemented with vitamin E(Pcreasing Hg concentration has resulted in a reduction in vitamin *** body fatty acids of fish like eicosapentaenoic acid(EPA) and docosahexaenoic acid(DHA) contents were decreased by dietary Hg. However, supplementation of dietary vitamin E improved the a-linolenic acid(ALA) and EPA contents in fish. Our results suggest that dietary supplementation of vitamin E has potential effects on growth improvement and ameliorating inorganic Hg bioaccumulation in juvenile olive flounder.

关键词： Vitamin E Mercury Growth Bioaccumulation Olive flounder