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Gravitational waves from cosmic strings after a first-order phase transition

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Chinese Physics C 2022年第4期46卷 34-39页

作者： Ruiyu Zhou ligong bian School of Science Chongqing University of Posts and TelecommunicationsChongqing 400065China Department of Physics Chongqing UniversityChongqing 401331China Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 401331China

We study the possibility of probing high scale phase transitions that are inaccessible by *** study shows that the stochastic gravitational-wave radiation from cosmic strings that are formed after the first-order phase transition can be detected by space-based interferometers when the phase transition temperature is T_(n)~O(10^(8−11))GeV.

关键词： new physics beyond the Standard Model gravitational-wave cosmic string first-order phase transition

Gravitational Waves, baryon asymmetry of the universe and electric dipole moment in the CP-violating NMSSM

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Chinese Physics C 2018年第9期42卷 56-70页

作者： ligong bian Huai-Ke Guo Jing Shu Department of Physics Chongqing University Chongqing 401331 China Department of Physics Chung-Ang University Seoul 06974 Korea CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of Sciences Beijing 100190 China CAS Center for Excellence in Particle Physics Beijing 100049 China School of Physical Sciences University of Chinese Academy of Sciences Beijing 100190 China Center for High Energy Physics Peking University Beijing 100871 China

In this work, we make the first study of electroweak baryogenesis（EWBG） based on the LHC data in the CP-violating next-to-minimal supersymmetric model（NMSSM） where a strongly first order electroweak phase transition（EWPT） is obtained in the general complex Higgs potential. With representative benchmark points which pass the current LEP and LHC constraints, we demonstrate the structure of EWPT for those points and how a strongly first order EWPT is obtained in the complex NMSSM where the resulting gravitational wave production properties are found to be within the reaches of future space-based interferometers like BBO and Ultimate-DECIGO. We further calculate the generated baryon asymmetries where the CP violating sources are（1）： higgsino-singlino dominated,（2）： higgsino-gaugino dominated or（3）： from both sources. It is shown that all three representing scenarios could evade the strong constraints set by various electric dipole moments（EDM） searches where cancellations among the EDM contributions occur at the tree level（higgsino-singlino dominated） or loop level（higgsino-gaugino dominated）.The 125 GeV SM like Higgs can be either the second lightest neutral Higgs H_2 or the third lightest neutral Higgs H_3. Finally, we comment on the future direct and indirect probe of CPV in the Higgs sector from the collider and EDM experiments.

关键词： finite-temperature field theory supersymmetric models electric and magnetic moments

Cosmological implications of a B−L charged hidden scalar:leptogenesis and gravitational waves

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Chinese Physics C 2021年第11期45卷 45-59页

作者： ligong bian Wei Cheng Huai-Ke Guo Yongchao Zhang Department of Physics Chongqing UniversityChongqing 401331China Chongqing Key Laboratory for Strongly Coupled Physics Chongqing 401331China School of Science Chongqing University of Posts and TelecommunicationsChongqing 400065China CAS key laboratory of theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190ChinaUniversity of Chinese Academy of SciencesBeijing 100190China Department of Physics and Astronomy University of OklahomaNormanOK 73019USA School of Physics Southeast UniversityNanjing 211189China Department of Physics and McDonnell Center for the Space Sciences Washington UniversitySt.LouisMO 63130USA Center for High Energy Physics Peking UniversityBeijing 100871China

In this study,we investigated the cosmological implications of a complex singlet scalar S with non-trivial B−L charges in the conformal U(1)B−L *** was found that,in a sizable region of parameter space,S may disturb the resonant leptogenesis mechanism,which is used to generate baryon asymmetry,and affect the symmetry breaking dynamics in the strong first order phase *** stochastic gravitational waves(GWs)produced at the phase transition can be probed in future GW *** GW searches prefer a relatively light S at the TeV-scale;however,this is difficult to detect directly at future high-energy colliders.

关键词： leptogenesis first-order phase transition gravitational wave

Inhibitory effects of Pseudomonas aeruginosa mannose-sensitive hemagglutinin on rat C6 glioma cell proliferation

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Neural Regeneration Research 2010年第11期5卷 868-873页

作者： Jie Sun Jianchang Cen Qian Chang Ping Su Zhiyong Yang Jinkun Wang Peng Ding Hang Yin Zhiqiang Shen Peng Chen Dianhua Wang ligong bian Xiaobin Song Jun Liu Department of Neurosurgery First People's Hospital of Kunming Kunming 650011 Yunnan Province China First Affifiated Hospital Kunming Medical College Kunming 650032 Yunnan Province China Kunming Medical College Kunming 650031 Yunnan Province China

BACKGROUND： Pseudomonas aeruginosa mannose-sensitive hemagglutinin （PA-MSHA） parenteral injection is used as a broad-spectrum immunomodulator. It remains unclear whether PA-MSHA exhibits inhibitory effects on tumor cell growth. OBJECTIVE： To investigate inhibitory mechanisms of PA-MSHA-induced proliferation in rat C6 glioma cells in vitro. DESIGN, TIME AND SETTING： Comparative observation and in vitro experiments were performed at the Key Laboratory of Natural Medicine, Kunming Medical College, China from July 2008 to April 2009. MATERIALS： Rat C6 glioma cell line （Shanghai Institute of Cell Biology, Chinese Academy of Sciences, China） and PA-MSHA parenteral injection （Beijing Wanteer Bio-Pharmaceutical, China） were used in the present study. METHODS： Rat C6 glioma cells in logarithmic growth phase were harvested in vitro. Adherent monolayer cells were respectively treated with PA-MSHA at final colony-forming units （cfu） of 1 ×10^8 cfu/mL, 2 × 10^8 cfu/mL, 4 × 10^8 cfu/mL, 6 × 10^8 cfu/mL, and 8 ×10^8 cfu/mL following 24 hours of conventional culture. MAIN OUTCOME MEASURES： MTT colorimetric assay was utilized to determine the inhibitory rate of C6 glioma cells following treatment with various concentrations of PA-MSHA at different times. Cell apoptosis was detected by fluorescent microscopy following Hoechst 33258 staining. Flow cytometry was used to measure PA-MSHA effects on C6 cell cycle. RESULTS： Inhibitory rate of C6 glioma cells increased with prolonged time and increased dose. Hoechst 33258 staining revealed obvious morphological changes in apoptotic C6 glioma cells. Flow cytometry revealed hypodiploid peaks, Le., apoptotic peak, and the apoptotic rate in cells during S-phase significantly increased with increased concentrations in the experimental groups. CONCLUSION： With in vitro experiments, PA-MSHA preparations inhibited C6 glioma cell proliferation in a time- and dose-dependent manner. These mechanisms are likely associated with cell apoptosis induction

关键词： C6 glioma cells Pseudomonas aeruginosa cell apoptosis in vitro culture rats

Erratum and Addendum:Gravitational Waves,baryon asymmetry of the universe and electric dipole moment in the CP-violating NMSSM(***.C,42(9):093106(2018))

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Chinese Physics C 2019年第12期43卷 188-188页

作者： ligong bian Huai-Ke Guo Jing Shu Department of Physics Chongqing UniversityChongqing 401331China Department of Physics Chung-Ang UniversitySeoul 06974Korea CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China CAS Center for Excellence in Particle Physics Beijing 100049China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China Center for High Energy Physics Peking UniversityBeijing 100871China

This paper was published online on 6 August 2018 with the acknowledgement of an author being *** acknowledgement of the last author,Jing Shu,should be added as“The work of JS is supported by the National Natural Science Foundation of China under grant No.11647601,No.11690022 and No.11675243 and also supported by the Strategic Priority Research Program of the Chinese Academy of Sciences under grant ***21010200 and *** of the results described in this paper are obtained on the HPC Cluster of SKLTP/ITP?CAS.”.

关键词： dipole viola moment

The Gravitational-wave physics Ⅱ: Progress

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Science China(Physics,Mechanics & Astronomy) 2021年第12期64卷 18-67页

作者： ligong bian Rong-Gen Cai Shuo Cao Zhoujian Cao He Gao Zong-Kuan Guo Kejia Lee Di Li Jing Liu Youjun Lu Shi Pi Jian-Min Wang Shao-Jiang Wang Yan Wang Tao Yang Xing-Yu Yang Shenghua Yu Xin Zhang CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Department of Astronomy Beijing Normal UniversityBeijing 100875China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100080China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced Study(HIAS)University of Chinese Academy of SciencesHangzhou 310024China MOE Key Laboratory of Fundamental Physical Quantities Measurements Hubei Key Laboratory of Gravitation and Quantum PhysicsNational Precise Gravity Measurement Facility(PGMF)Department of Astronomy and School of PhysicsHuazhong University of Science and TechnologyWuhan 430074China Asia Pacific Center for Theoretical Physics Pohang 37673Korea Department of Physics College of SciencesNortheastern UniversityShenyang 110819China Key Laboratory of Data Analytics and Optimization for Smart Industry(Northeastern University) Ministry of EducationShenyang 110819China Department of Physics Chongqing UniversityChongqing 401331China

It has been a half-decade since the first direct detection of gravitational waves, which signifies the coming of the era of the gravitational-wave astronomy and gravitational-wave cosmology. The increasing number of the detected gravitational-wave events has revealed the promising capability of constraining various aspects of cosmology, astronomy, and gravity. Due to the limited space in this review article, we will briefly summarize the recent progress over the past five years, but with a special focus on some of our own work for the Key Project "Physics associated with the gravitational waves" supported by the National Natural Science Foundation of China. In particular,(1) we have presented the mechanism of the gravitational-wave production during some physical processes of the early Universe, such as inflation, preheating and phase transition, and the cosmological implications of gravitational-wave measurements;(2) we have put constraints on the neutron star maximum mass according to GW170817 observations;(3) we have developed a numerical relativity algorithm based on the finite element method and a waveform model for the binary black hole coalescence along an eccentric orbit.

关键词： gravitational wave gravitational-wave cosmology gravitational-wave astronomy numerical relativity

骨髓间充质干细胞不同移植方法治疗脊髓损伤的实验研究

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神经解剖学杂志 2007年第6期23卷 635-638页

作者：陈东杨晓华边立功杨波李明昆明医学院解剖学教研室昆明650031 昆明医学院康复研究所昆明650031

为探讨骨髓基质干细胞(MSCs)不同的移植方法对脊髓损伤修复的影响,我们采用静脉移植、蛛网膜下腔移植或腹腔移植荧光标记MSCs的方法检测MSCs在损伤处的分布迁移情况及运动功能恢复情况。结果显示:各种移植方法在损伤脊髓节段上、下均可... 详细信息

为探讨骨髓基质干细胞(MSCs)不同的移植方法对脊髓损伤修复的影响,我们采用静脉移植、蛛网膜下腔移植或腹腔移植荧光标记MSCs的方法检测MSCs在损伤处的分布迁移情况及运动功能恢复情况。结果显示:各种移植方法在损伤脊髓节段上、下均可检测到荧光标记的MSCs,不同移植方法在损伤脊髓内荧光标记的MSCs数量有所不同。损伤脊髓节段和非损伤脊髓节段内的细胞数量和密度也有明显差异(P0.05);3周后,各组间差异也不大(P>0.05),但各移植组同对照组相比有明显差异(P<0.05)。以上结果提示:通过各种移植方法MSCs均可迁移到损伤脊髓节段,并在该部位存活、聚集和向损伤部位迁移,说明MSCs不同的移植方法对于治疗脊髓损伤均有一定的作用。

关键词：骨髓基质干细胞移植脊髓损伤 BBB评分大鼠

天麻素调控Nrf2信号通路在癫痫中的抗炎作用

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神经解剖学杂志 2018年第2期34卷 147-152页

作者：秦瑞怡边立功钟莲梅艾青龙陈鑫月张如秋张颖陆地昆明医科大学病理学与病理生理学系昆明650500 昆明医科大学人体解剖学与组织胚胎学系昆明650500 昆明医科大学第一附属医院神经内科昆明650500 昆明医科大学2015级临床医学昆明650500 昆明医科大学生物医学工程研究中心昆明650500

目的:探讨天麻素调控nuclear factor erythroid 2-related factor 2(Nrf2)信号通路在癫痫中的抗炎作用及发挥神经保护作用的新机制。方法:100只SD大鼠,随机分为5组:空白对照组,模型组,50 mg/kg天麻素治疗组,100 mg/kg天麻素治疗组,200 m... 详细信息

目的:探讨天麻素调控nuclear factor erythroid 2-related factor 2(Nrf2)信号通路在癫痫中的抗炎作用及发挥神经保护作用的新机制。方法:100只SD大鼠,随机分为5组:空白对照组,模型组,50 mg/kg天麻素治疗组,100 mg/kg天麻素治疗组,200 mg/kg天麻素治疗组。模型组构建氯化锂-匹罗卡品SD大鼠癫痫模型,治疗组采用天麻素进行干预。Racine分级标准判断模型是否构建成功,免疫印迹法及免疫荧光染色的方法检测Nrf2、血红素氧合酶-1(HO-1)、诱导型一氧化氮合酶(iNOS)的表达含量。结果:与空白对照组相比,模型组小胶质细胞中抗氧化蛋白Nrf2和HO-1表达略有上调,炎症因子iNOS表达显著增加;经天麻素预处理的治疗组小胶质细胞中Nrf2和HO-1蛋白表达较模型组增加,而炎症因子iNOS的表达减少。结论:天麻素可能通过调控Nrf2/HO-1经典抗氧化信号通路,降低炎症因子iNOS的表达,从而在癫痫中发挥神经保护作用。

关键词：天麻素 Nrf2 癫痫信号通路炎症血红素氧合酶-1

白藜芦醇调控癫痫持续状态大鼠大脑皮质内源性巯醇抗氧化剂(酶)的作用研究

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神经解剖学杂志 2011年第4期27卷 383-388页

作者：李燕玲郭家智钟莲梅边立功傅希玥艾青龙王文敏陆地昆明医学院附属第一医院神经内科昆明650032 人体解剖学教研室昆明650500

目的:探讨白藜芦醇(resveratrol,Res)在氯化锂(LiCl)-重复低剂量匹罗卡品(pilocarpine,Pilo)诱导癫痫持续状态(status epilepticus,SE)大鼠模型中的抗氧化作用及其机制。方法:54只SD大鼠随机分为3组:对照组、癫痫模型组和Res治疗组。采... 详细信息

目的:探讨白藜芦醇(resveratrol,Res)在氯化锂(LiCl)-重复低剂量匹罗卡品(pilocarpine,Pilo)诱导癫痫持续状态(status epilepticus,SE)大鼠模型中的抗氧化作用及其机制。方法:54只SD大鼠随机分为3组:对照组、癫痫模型组和Res治疗组。采用重复低剂量氯化锂-联合皮罗卡品腹腔注射制备癫痫持续状态SD大鼠模型,并同时给予Res预防性治疗,对实验动物按痫性分级标准进行行为学观测,采用化学比色法检测痫性发作90min后模型动物大脑皮质过氧化氢酶(catalase,CAT)、谷胱甘肽(glutathion,GSH)、超氧化物歧化酶(superoxidedismutase,SOD)和谷胱甘肽还原酶(glutathion reductase,GR)含量变化。采用免疫组织化学法和免疫印迹法(Western blot)检测痫性发作90 min后模型动物大脑皮质中凋亡相关蛋白Bcl-2、Caspase-3和Bax的表达变化。结果:癫痫大鼠大脑皮质CAT、GR、SOD和GSH的含量较对照组显著减少(P<0.05),凋亡相关蛋白Bcl-2表达下调,该蛋白阳性细胞数减少,而caspase-3和Bax表达显著上调(P<0.05),两种蛋白阳性细胞数增多(P<0.05);Res预防性治疗后,治疗组动物痫性发作潜伏期较模型组显著延长(P<0.05);药物治疗明显上调模型动物大脑皮质中巯醇抗氧化剂(酶)CAT、GR、SOD和GSH的含量(P<0.05),增加抗凋亡蛋白Bcl-2表达(P<0.05)和阳性细胞数(P<0.05),同时抑制促凋亡因子Caspase-3和Bax的表达(P<0.05)和减少两种蛋白阳性细胞数(P<0.05)。结论:Res能通过上调癫痫模型大鼠皮质内源性巯基抗氧化物(酶)CAT、GR、SOD和GSH的含量,调控凋亡相关蛋白Bcl-2、caspase-3和Bax的表达变化,对抗SE诱导的神经细胞氧化损伤,发挥神经保护作用。

关键词：癫痫白藜芦醇匹罗卡品巯醇抗氧化物(酶) 凋亡相关蛋白大鼠