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Data Security and Privacy in Bitcoin System:A Survey

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Journal of Computer Science & Technology 2020年第4期35卷 843-862页

作者： lie-Huang zhu Bao-Kun Zheng Meng Shen Feng Gao Hong-Yu Li Ke-Xin Shi School of Computer Science and Technology Beijing Institute of TechnologyBeijing 100081China School of Information Management for Law China University of Political Science and LawBeijing 102249China Key Laboratory of Information Network Security Ministry of Public SecurityShanghai 201204China

To date,bitcoin has been the most successful application of blockchain technology and has received considerable attention from both industry and *** is an electronic payment system based on cryptography rather than on *** of whether people are in the same city or country,bitcoin can be sent by any one person to any other person when they reach an *** market value of bitcoin has been rising since its advent in 2009,and its current market value is US160 *** its development,bitcoin itself has exposed many problems and is facing challenges from all the sectors of society;therefore,adversaries may use bitcoin's weakness to make considerable *** survey presents an overview and detailed investigation of data security and privacy in bitcoin *** examine the studies in the literature/Web in two categories:1)analyses of the attacks to the privacy,availability,and consistency of bitcoin data and 2)summaries of the countermeasures for bitcoin data *** on the literature/Web,we list and describe the research methods and results for the two *** compare the performance of these methods and illustrate the relationship between the performance and the ***,we present several important open research directions to identify the follow-up studies in this area.

关键词： security privacy bitcoin availability consistency

Scalable and Privacy-Preserving Data Sharing Based on Blockchain

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Journal of Computer Science & Technology 2018年第3期33卷 557-567页

作者： Bao-Kun Zheng lie-Huang zhu Meng Shen Feng Gao Chuan Zhang Yan-Dong Li Jing Yang School of Computer Science and Technology Beijing Institute of Technology Beijing 100081 China School of Information Management for Law China University of Political Science and Law Beijing 102249 China

With the development of network technology and cloud computing, data sharing is becoming increasingly popular, and many scholars have conducted in-depth research to promote its flourish. As the scale of data sharing expands, its privacy protection has become a hot issue in research. Moreover, in data sharing, the data is usually maintained in multiple parties, which brings new challenges to protect the privacy of these multi-party data. In this paper, we propose a trusted data sharing scheme using blockchain. We use blockchain to prevent the shared data from being tampered, and use the Paillier cryptosystem to realize the confidentiality of the shared data. In the proposed scheme, the shared data can be traded, and the transaction information is protected by using the （p, t）-threshold Paillier cryptosystem. We conduct experiments in cloud storage scenarios and the experimental results demonstrate the efficiency and effectiveness of the proposed scheme.

关键词： data sharing privacy-preserving cloud computing blockchain Paillier cryptosystem

Expression of NG2 and platelet-derived growth factor receptor alpha in the developing neonatal rat brain

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Neural Regeneration Research 2017年第11期12卷 1843-1852页

作者： Ping Li Heng-xi Li Hong-yan Jiang lie zhu Hai-ying Wu Jin-tao Li Jiang-hua Lai College of Forensic Science Health Science CenterXi'an Jiaotong UniversityXi'anShaanxi ProvinceChina Department of Anatomy and Histology&Embryology Faculty of Basic Medical SciencesKunming Medical UniversityKunmingYunnan ProvinceChina Department of Plastic Surgery Changzheng HospitalShanghaiChina Department of Emergency and Intensive Care Unit First Affiliated HospitalKunming Medical UniversityKunmingYunnan ProvinceChina Neuroscience Institute Faculty of Basic Medical SciencesKunming Medical UniversityKunmingYunnan ProvinceChina

Platelet-derived growth factor receptor alpha （PDGFRct） is a marker of oligodendrocyte precursor cells in the central nervous system. NG2 is also considered a marker of oligodendrocyte precursor cells. However, whether there are differences in the distribution and morphol- ogy of oligodendrocyte precursor cells labeled by NG2 or PDGFRa in the developing neonatal rat brain remains unclear. In this study, by immunohistochemical staining, NG2 positive （NG2＋） cells were ubiquitous in the molecular layer, external pyramidal layer, internal pyramidal layer, and polymorphic layer of the cerebral cortex, and corpus callosum, external capsule, piriform cortex, and medial septal nucleus. NG2~ cells were stellate or fusiform in shape with long processes that were progressively decreased and shortened over the course of brain development. The distribution and morphology of PDGFRct positive （PDGFRa＋） cells were coincident with NG2＋ cells. The co- localization of NG2 and PDGFRu in the cell bodies and processes of some cells was confirmed by double immunofluorescence labeling. Moreover, cells double-labeled for NG2 and PDGFRa were predominantly in the early postnatal stage of development. The numbers of NG2＋/PDGFRa＋ cells and PDGFRa＋ cells decreased, but the number of NG2＋ cells increased from postnatal days 3 to 14 in the developing brain. In addition, amoeboid microglial cells of the corpus callosum, newborn brain macrophages in the normal developing brain, did not express NG2 or PDGFRu, but NG2 expression was detected in amoeboid microglia after hypoxia. The present results suggest that NG2 and PDGFRct are specific markers of oligodendrocyte precursor cells at different stages during early development. Additionally, the NG2 protein is involved in inflammatory and pathological processes of amoeboid microglial cells.

关键词： nerve regeneration NG2 platelet-derived growth factor receptor alpha oligodendrocyte precursor cells amoeboid microglial cells OX-42 hypoxia cerebral cortex corpus callosum neural regeneration

Risk factors of portal vein thrombosis after splenectomy in patients with liver cirrhosis

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Hepatoma Research 2020年第7期6卷 1-13页

作者： Ze-long Yang Ting Guo Dong-lie zhu Shi Zheng Dan-Dan Han Yong Chen Department of Hepatobiliary Surgery Xijing HospitalFourth Military Medical UniversityXi'an 710032ShaanxiChina Department of Obstetrics Huaxi HospitalSichuan UniversityCheng Du 610011Si ChuanChina.

Portal vein thrombosis(PVT)is a common complication after splenectomy,causing a possible negative impact on the prognosis of patients with liver ***,the risk factors of PVT are not completely *** factors are related to the occurrence of postoperative PVT,such as hemodynamic changes,splenomegaly,splenectomy,coagulation and anticoagulation disorder,liver cirrhosis,platelet count,D-dimer level,infection,inflammation,and other *** changes are mainly caused by thicker portal and splenic vein diameters,larger spleen,slower portal vein blood flow rate,lower portal vein pressure before and after surgery,*** is timely detection and advanced prevention that really matter in reducing PVT incidence and improving patient *** systematically reviewed the researches on the risk factors and therapies of PVTto provide useful information on a comprehensive understanding for researchers.

关键词： Liver cirrhosis splenectomy portal vein thrombosis risk factors treatments prophylaxis

Extracellular vesicles derived from mesenchymal stem cells:the wine in Hebe's hands to treat skin aging

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Precision Clinical Medicine 2024年第2期7卷 170-189页

作者： Qixiang Gui Neng Ding Zuochao Yao Minjuan Wu Ruifeng Fu Yue Wang Yunpeng Zhao lie zhu Department of Plastic and Reconstructive Surgery Second Affliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)Shanghai 20o001China Department of Plastic and Reconstructive Surgery of Shanghai East Hospital School of MedicineTongji UniversityShanghai 200120China Department of Histology and Embryology Naval Medical UniversityShanghai 200433China Shanghai Key Laboratory of Cell Engineering Translational Medical Research CenterNaval Medical UniversityShanghai 200433China hanghai Institute of Stem Cell Research and Clinical Translation Shanghai 200092China

Owing to its constant exposure to the external environment and various stimuli,skin ranks among the organs most vulnerable to manifestations of *** and delaying skin aging has become one of the prominent research subjects in recent *** stem celis(MsCs)are multipotent stem cells derived from mesoderm with high self-renewal ability and multilineage differentiation ***-derived extracellular vesicles(MSC-EVs)are nanoscale biological vesicles that facilitate intercellular communication and regulate biological *** studies have shown that MSC-EVs have potential applications in anti-aging therapy due to their anti-inflammatory,anti-oxidative stress,and wound healing promoting *** review presents the latest progress of MSC-EVs in delaying skin *** mainly includes the MSC-EVs promoting the proliferation and migration of keratinocytes and fibroblasts,reducing the expression of matrix metalloproteinases,resisting oxidative stress,and regulating *** then briefly discuss the recently discovered treatment methods of MSc-EVs in the field of skin ***,the advantages and limitations of EV-based treatments are also presented.

关键词： mesenchymal stem cell extracellular vesicles exosomes skin aging anti-aging photoaging

Inhaled nitric oxide attenuates hyperoxic lung injury in adult rats

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Acta Pharmacologica Sinica 2003年第12期 170-171页

作者： HU Xiao-Wei, zhu lie-Wei, SUN Bo Laboratory of Respiratory and Intensive Care, Children’s Hospital, Fudan University, Shanghai 200032, China

BACKGROUND: Hyperoxic lung injury is commonly encountered in the treatment of premature neonates with respiratory distress, and impairment of and deficiency in antioxidant system in airway and alveolar epithelial cells may cause chronic lung disease (CLD). This problem may also be found in infants and children subjected to long term, high oxygen treatment. Inhaled nitric oxide (iNO) as a selective pulmonary vasodilator may possess both anti-inflammatory and antioxidant properties, which modulate cellular mechanism against hyperoxic injury in the mature lungs caused by oxygen toxicity and free radicals released from inflammatory cells. We investigated whether iNO at therapeutic dose may attenuate hyperoxia related lung injury, with special emphasis on oxidative damage, inflammation, permeability and pulmonary surfactant composition, function and metabolism. METHODS: Healthy adult male SD rats weighing 165-235 g were placed in a plexiglas chamber. Oxygen (95％) and NO at 20 ppm were mixed immediately and

关键词： lung on as were of Inhaled nitric oxide attenuates hyperoxic lung injury in adult rats in

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高氧液对颅脑交通伤家兔神经细胞凋亡的影响

中华创伤杂志 2008年第9期24卷 740-742页

作者：陈大庆朱烈烈温州医学院附属第二医院急诊科 325027

目的探讨静脉输注高氧液对颅脑交通伤家兔神经细胞凋亡的影响。方法筛选合适的撞击速度制作家兔颅脑交通伤模型成功后，每日分别给予高氧液25，50，75，100ml治疗。观察各组动物的线粒体呼吸控制率（RCR）、膜电位（MMP）、神经细胞凋... 详细信息

目的探讨静脉输注高氧液对颅脑交通伤家兔神经细胞凋亡的影响。方法筛选合适的撞击速度制作家兔颅脑交通伤模型成功后，每日分别给予高氧液25，50，75，100ml治疗。观察各组动物的线粒体呼吸控制率（RCR）、膜电位（MMP）、神经细胞凋亡率的改变，以及神经损害程度评分（NSS）的变化。结果经过筛选，以72km／h的撞击速度制作的脑损伤模型为研究对象，与未干预组相比，对照组和治疗组脑线粒体MMP、RCR、磷氧比（P／O）及氧化磷酸化率（OPR），神经细胞凋亡率和NSS差异均有统计学意义（P〈0．05）。100ml高氧液治疗组的MMP、RCR、P／O及OPR水平要优于75ml高氧液治疗组（P〈0．05），而神经细胞凋亡率和NSS则低于75ml高氧液治疗组，但差异无统计学意义（P〉0．05）。结论静脉输注高氧液能降低颅脑损伤后神经细胞凋亡率，通过干预线粒体功能可能是高氧液影响神经细胞凋亡从而改善预后的重要途径之一。

关键词：脑损伤事故,交通线粒体凋亡高氧液

多发伤患者外周血降钙素原及C反应蛋白的动态变化及意义

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中华创伤杂志 2007年第1期23卷 52-55页

作者：陈大庆朱烈烈温州医学院附属第二医院急诊科 325027

目的探讨多发伤患者外周血降钙素原（procalcitonin，PCT）与C反应蛋白（C reacfive protein，CRP）的动态变化及其临床意义。方法将96例多发伤患者按照ISS、输血量的多少、有无MODS、感染、脓毒血症及预后情况进行分类，分别检测不... 详细信息

目的探讨多发伤患者外周血降钙素原（procalcitonin，PCT）与C反应蛋白（C reacfive protein，CRP）的动态变化及其临床意义。方法将96例多发伤患者按照ISS、输血量的多少、有无MODS、感染、脓毒血症及预后情况进行分类，分别检测不同类别患者外周血PCT、CRP浓度。结果与对照组相比，多发伤患者PCT和CRP均明显升高，其峰值分别出现在伤后2d（PCT），5，7d（CRP）。发生MODS、感染及脓毒血症时，PCT和CRP均明显升高。此外，PCT还与患者ISS评分、预后和输血量具有相关性。结论联合检测PCT、CRP有助于多发伤患者伤情的诊治及预后判断，其中PCT较CRP更具有敏感性。

关键词：多处创伤降钙素原 C反应蛋白质

STUDY ON PERFORMANCE OF COMPOSITE JOURNAL BEARING SEALED AND LUBRICATED WITH FERROFLUID

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Chinese Journal of Mechanical Engineering 1998年第3期11卷 2-7页

作者： Zhang Song Kong Xianmei Chen Darong National Tribology Laboratory,Qinghua University Yu lie zhu Jun Xi’an Jiaotong University

The theoretical computation model of the composite journal bearing sealed and lubricated with ferrofluid is established The oil film pressure distribution,temperature field and heat conduction equation of the bearing liner are jointly calculated The static and dynamic properties of the bearing under condition of different eccentricities and ratios of width to diameter are obtained and discussed The results show the feasibility of this type of bearing for smaller eccentricities and width to diameter ratios,and that the oil film temperature,which is more subject to be influenced by the rotating speed,is higher than that of the bearing with leakage flow The key problem of the further development and application of the bearing is to design more reasonable and effective types of seal structures

关键词： Ferrofluid Journal bearing Self seal