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低空经济时代地理信息科技发展的机遇和挑战

地球信息科学学报 2025年第1期27卷 1-9页

作者：廖小罕黄耀欢刘霞中国科学院地理科学与资源研究所地理信息科学与技术全国重点实验室北京100101 中国地理信息产业协会无人机应用与管控工作委员会北京100053 中国民航局低空地理信息与航路重点实验室北京100101 北京清源四维科技有限公司北京100015 中国科学院大学资源与环境学院北京100049

【意义】低空经济作为新质生产力代表,正逐渐成为推动经济增长的新引擎。低空经济以低空空域资源开发利用为基础,在给地理信息科技带来发展机遇的同时也对其提出了全新的挑战。【进展与分析】本文首先对低空经济下低空空域资源划分以及... 详细信息

【意义】低空经济作为新质生产力代表,正逐渐成为推动经济增长的新引擎。低空经济以低空空域资源开发利用为基础,在给地理信息科技带来发展机遇的同时也对其提出了全新的挑战。【进展与分析】本文首先对低空经济下低空空域资源划分以及典型无人机应用场景进行了介绍,进而分析了地理信息科技将在空域资源精细化利用与低空环境构建、空中交通新型基础设施规划建设运行、无人机安全高效运行与运营监管等低空经济关键环节具有广泛应用前景,指出地理信息产业也将面临新的技术融合与创新、市场需求增长、政策支持与产业引导、产业升级与转型等发展机遇。【展望】本文简要分析了地理信息科技支撑低空经济发展所面临的时空升维、地图和位置服务、高频次迅捷数据获取体系、全时全域能力和泛在智能化技术等挑战,这些也将成为地理信息科技未来可以发展和突破的方向。

关键词：低空经济地理信息科技地理信息产业发展机遇挑战

9-Year Clinical Audit on Complications of Cleft Lip and Palate Charity Surgeries in China Shenzhen Area

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International Journal of Otolaryngology and Head & Neck Surgery 2025年第1期14卷 19-28页

作者： Yangliu liao Takkun Chow Sikkuen Chow Wenbo Huang Deheng Chen Huizhi Zeng Division of Plastic and Reconstructive Surgery Department of Surgery The University of Hong Kong-Shenzhen Hospital Shenzhen China Department of Surgery The University of Hong Kong Hong Kong China

Background: In developing countries, charity cleft surgical mission is always operated by sporadic surgical teams without systematic follow up and quality assurance. In the past few decades, many mission projects have been held regularly in China. The purpose of this audit was a retrospective analysis of a 9-year cleft lip and palate charity project operated in a tertiary hospital in China Shenzhen Area to evaluate perioperative and postoperative complications. Nevertheless, understanding the risk profile is essential for establishing a sustainable in-house cleft service in Shenzhen. Methods: A detailed analysis of hospital centralized record in the The University of Hong Kong-Shenzhen Hospital (HKUSZH) was reviewed since the first charity project held in 2015. The parameters of this audit were focused on perioperative complications including anesthesia related problems, early postoperative complications in patients who underwent primary or secondary cleft surgeries. A total of 430 consecutive admitted cases of 311 non-syndromic cleft lip & palate patients were enrolled into the charity project from June 2015 to July 2024. The main anesthesia related complications that occurred during general anesthesia were respiratory tract problems, while intraoperative complication was excessive bleeding, so as wound local infection and reaction were the main early postoperative complications. Results: In our 9-year clinical audit of 430 cleft lip and palate charity surgeries in Shenzhen, we observed no mortalities and a anesthesia-related complication rate of 1.16%. Specific intraoperative complications included excessive bleeding, while early postoperative issues were dominated by wound infections. The fistula rate of 18.7% post palate repair and the average hospital stay of 3.71 days complete the profile of our surgical outcomes. These data underscore the project’s efficacy and offer a reference for international cleft missions aiming for safe and efficient surgical care. Con

关键词： Cleft Lip Cleft Palate Charity Surgery Complication

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巴伦支海西南海域风浪设计参数估计研究

哈尔滨工程大学学报 2025年第1期46卷 71-78页

作者：廖振焜董胜中国海洋大学工程学院山东青岛266404

巴伦支海蕴含丰富的油气资源,但环境条件复杂,常发生以极地低压为代表的极端天气过程。为了研究受极地低压影响的巴伦支海西南海域风浪设计参数,给在此作业的海洋工程结构提供参考,本文基于ERA5再分析数据,识别影响巴伦支海的极地低压过... 详细信息

巴伦支海蕴含丰富的油气资源,但环境条件复杂,常发生以极地低压为代表的极端天气过程。为了研究受极地低压影响的巴伦支海西南海域风浪设计参数,给在此作业的海洋工程结构提供参考,本文基于ERA5再分析数据,识别影响巴伦支海的极地低压过程,选取代表点提取其过程极值序列,基于复合极值分布理论建立考虑多种过程的风速、波浪环境设计参数估计模型,推算设计重现值,与年极值法计算结果进行了比较。研究表明:通过考虑极地低压过程,抽取过程极值序列,包含了更多的情况,适当降低环境设计参数值,结果更加符合实际。

关键词：巴伦支海极地低压风速波高过程极值复合极值分布统计分析设计参数

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面向低空经济产业的无人机监管体系研究——基于美国经验的思考

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中国流通经济 2025年第2期39卷 16-29页

作者：廖慧姣同济大学法学院上海市200092

低空经济是以无人机产业为主导的产业融合发展的综合经济形态,正在成为推动全球经济增长的新引擎和驱动新质生产力发展的重要力量。然而,我国现行无人机监管体系主要沿用传统航空监管框架,以风险管控为中心,以强制性监管为主,围绕主体... 详细信息

低空经济是以无人机产业为主导的产业融合发展的综合经济形态,正在成为推动全球经济增长的新引擎和驱动新质生产力发展的重要力量。然而,我国现行无人机监管体系主要沿用传统航空监管框架,以风险管控为中心,以强制性监管为主,围绕主体、对象、行为三大核心要素展开,无论在监管理念、监管内容,还是监管措施上,均与低空经济产业需求存在错位,对技术创新缺乏包容性,不利于无人机产业落地推广。美国在低空经济领域表现杰出,这源自其在无人机监管领域的前瞻性布局,其促进创新的适度监管、对技术和产业需求的回应、积极倡导的合作治理和服务性监管,为低空经济产业规范化运营和可持续发展奠定了坚实的制度基础。鉴于此,可借鉴美国经验,从监管理念、监管内容、监管措施三个维度对我国无人机监管体系做进一步调整:从监管理念看,应从单一风险管控转向安全保障与创新促进并进;从监管内容看,应着重优化主体、对象、行为三个关键要素以回应低空经济创新需求,包括考虑智能等级、按需分级管理的资质管理体系,建立技术标准的差距识别追踪和动态更新机制,细化视距内与超视距运行规则,增加多机协同、屏蔽操作等运行规范,并针对隐私侵害、噪声污染等新型风险制定专项法规;从监管措施看,应积极推动多方协同治理,以及强制性监管向服务性监管的转变。

关键词：低空经济无人机监管体系美国

Exploring the mechanism of Xiaoaiping Injection inhibiting autophagy in prostate cancer based on proteomics

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Chinese Journal of Natural Medicines 2025年第1期23卷 64-76页

作者： Qiuping Zhang Qiuju Huang Zhiping Cheng Wei Xue Shoushi Liu Yunnuo liao Xiaolan Li Xin Chen Yaoyao Han Dan Zhu Zhiheng Su Xin Yang Zhuo Luo Hongwei Guo Department of Traditional Chinese Medicine the First Affiliated Hospital of Guangxi Medical University Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation & College of Pharmacy Guangxi Medical University Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education & Center for Translational Medicine Guangxi Medical University

Xiaoaiping(XAP) Injection demonstrates the anti-prostate cancer(PCa) effects, yet the underlying mechanism remains unclear. This study aims to investigate the impact of XAP on PCa and elucidate its mechanism of action. PCa cell proliferation was evaluated using a cell counting kit-8(CCK-8) assay. Cell apoptosis was assessed through Hoechst staining and Western blotting assays. Proteomics technology was employed to identify key molecules and significant signaling pathways modulated by XAP in PCa cells. To further validate potential key genes and important pathways, a series of assays were conducted, including acridine orange(AO)staining, transmission electron microscopy, and immunofluorescence assays. The molecular mechanism of XAP against PCa in vivo was examined using a PC3 xenograft mouse model. Results demonstrated that XAP significantly inhibited cell proliferation in multiple PCa cell *** C4-2 and prostate cancer cell line-3(PC3) cells, XAP induced cellular apoptosis, evidenced by reduced B-cell lymphoma 2(Bcl-2) levels and elevated Bcl-2-associated X(Bax) levels. Proteomic, immunofluorescence, and quantitative reverse transcription-polymerase chain reaction(q RT-PCR) investigations revealed a strong correlation between forkhead box O3a(Fox O3a) autophagic degradation and the anti-PCa action of XAP. XAP hindered autophagy by reducing the expression levels of autophagy-related protein 5(Atg5)/autophagy-related protein 12(Atg12) and enhancing Fox O3a expression and nuclear translocation. Furthermore,XAP exhibited potent anti-PCa action in PC3 xenograft mice and triggered Fox O3a nuclear translocation in tumor tissue. These findings suggest that XAP induces PCa apoptosis via inhibition of Fox O3a autophagic degradation, potentially offering a novel perspective on XAP injection as an effective anticancer therapy for PCa.

关键词： Apoptosis Autophagy Forkhead box O3a Prostate cancer Xiaoaiping Injection

Enhanced risk assessment framework integrating distribution dynamics, genetically inferred populations, and morphological traits of Diploderma lizards

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Zoological Research 2025年第01期 15-26页

作者： Qi Xiao Xiu-Dong Shi Lin Shi Zhong-Yi Yao You-Hua Chen Wei-Zhao Yang Zi-Yan liao Yin Qi Chengdu Institute of Biology Chinese Academy of Sciences University of Chinese Academy of Sciences Mangkang Ecological Station Xizang Ecological Safety Monitor Network

Assessing the threat status of species in response to global change is critical for biodiversity monitoring and conservation efforts. However, current frameworks, even the IUCN Red List, often neglect critical factors such as genetic diversity and the impacts of climate and land-use changes, hindering effective conservation planning. To address these limitations, we developed an enhanced extinction risk assessment framework using Diploderma lizards as a model. This framework incorporates long-term field surveys, environmental data, and land-use information to predict distributional changes for 10 recently described Diploderma species on the Qinghai-Xizang Plateau, which hold ecological significance but remain underassessed in conservation assessment. By integrating the distribution data and genetically inferred effective population sizes(Ne), we conducted scenario analyses and used a rank-sum approach to calculate Risk ranking scores(RRS) for each species. This approach revealed significant discrepancies with the IUCN Red List assessments. Notably, D. yangi and D. qilin were identified as facing the highest extinction risk. Furthermore, D. vela,D. batangense, D. flaviceps, D. dymondi, D. yulongense,and D. laeviventre, currently classified as “Least Concern”,were found to warrant reclassification as “Vulnerable” due to considerable threat from projected range *** the relationship between morphology and RRS revealed that traits such as snout-vent length and relative tail length could serve as potential predictors of extinction risk, offering preliminary metrics for assessing species vulnerability when comprehensive data are *** study enhances the precision of extinction risk assessment frameworks and demonstrates their capacity to refine and update risk assessments, especially for lesser-known taxa.

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Anti-breast cancer effect of quercetin nanoparticles based on MOFs for chemo-phototherapy and heat shock proteins inhibition

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Nano Research 2025年第1期18卷 545-558页

作者： Rongyue Zhu Shilang liao Mengru Cai Dongge Yin Tingting Fu Jing Liu Yuji Du Jiahui Kong Rongrong Chang Jian Ni Xingbin Yin Beijing University of Chinese Medicine Fangshan DistrictBeijing 102488China

Phototherapy, including photodynamic therapy(PDT) and photothermal therapy (PTT), is a promisingmethod of tumor treatment, which has the advantages ofstrong specificity and small side effects. However, PDT willaggravate the hypoxic environment in tumor cells, and PTTwill lead to heat-resistant reaction, both of which will make theorganism quickly produce heat shock proteins (HSPs) toprotect itself, thus seriously hindering the therapeuticefficiency of phototherapy. As a natural HSPs inhibitor,quercetin (QR) provides a feasible way to solve this ***, a kind of metal organic framework (MOF), Fe-TCPP(FT), was used as a delivery material and photosensitizer tobuild a chemo-phototherapy platform, and QR was used as achemotherapy drug and HSPs inhibitor. On this basis, the nanoparticles (NPs) were modified with PEG-CPP30 (a cellpenetratingpeptide that specifically recognizes human breast cancer MCF-7 cells), which showed excellent targetingcapacity and biocompatibility. The combination of chemotherapy and phototherapy significantly improved the anti-cancereffect. At the same time, NPs also showed prominent anti-HSPs effect. The effective connection of the two played acomplementary role in the process of tumor treatment, which provided a new strategy for the accurate and efficienttreatment of tumors in the future.

关键词： quercetin Fe-metal organic frameworks(MOFs) phototherapy anti-cancer heat shock proteins inhibition

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fgOTN关键技术和组网应用研究

电信科学 2025年第1期41卷 42-53页

作者：廖尚金华信咨询设计研究院有限公司浙江杭州310051

随着5G+垂直行业、高品质政企专线的发展,细颗粒业务需求仍然保持旺盛的生命力。从细颗粒光传送网(fine grain optical transport network,fgOTN)的技术发展入手,重点阐述fgOTN的关键技术方案,开展组网研究,探讨fgOTN的应用场景,旨在为... 详细信息

随着5G+垂直行业、高品质政企专线的发展,细颗粒业务需求仍然保持旺盛的生命力。从细颗粒光传送网(fine grain optical transport network,fgOTN)的技术发展入手,重点阐述fgOTN的关键技术方案,开展组网研究,探讨fgOTN的应用场景,旨在为各运营商如何结合现网部署fgOTN提供借鉴思路,从而有效保护网络投资,最终推进fgOTN在国内网络的部署和应用。

关键词： fgODUflex帧结构细颗粒技术 fgOTN部署

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基于消息传递的OTFS信号检测算法综述

电讯技术 2025年第2期65卷 188-198页

作者：廖勇于晨重庆大学微电子与通信工程学院重庆400044

由于正交时频空(Orthogonal Time Frequency Space, OTFS)调制解决了多普勒频移的影响,能够适应快时变信道下的传输要求,已成为第六代(The Sixth Generation, 6G)移动通信系统中关键候选技术。同时,信号检测对OTFS在信道传输中的性能发... 详细信息

由于正交时频空(Orthogonal Time Frequency Space, OTFS)调制解决了多普勒频移的影响,能够适应快时变信道下的传输要求,已成为第六代(The Sixth Generation, 6G)移动通信系统中关键候选技术。同时,信号检测对OTFS在信道传输中的性能发挥着重要作用。目前消息传递(Message Passing, MP)算法作为主流的信号检测算法,在OTFS系统中被广泛使用。然而,在实际环境下MP信号检测算法仍面临着诸多技术挑战。首先介绍了OTFS系统的基本原理和信号处理流程,其次对MP算法的信号检测原理进行阐述,然后将MP的优化算法分为4类,分别为近似消息传递(Approximate Message Passing, AMP)算法、高斯近似消息传递(Gaussian Approximate Message Passing, GAMP)算法、正交近似消息传递(Orthogonal Approximate Message Passing, OAMP)算法以及单元近似消息传递(Unitary Approximate Message Passing, UAMP)算法,对各类算法分别概述其原理并进行了分析、归纳和总结,接着对MP及其优化算法面临的技术挑战进行了探讨,最后对其未来的发展趋势进行了展望。

关键词： 6G 正交时频空(OTFS) 信号检测消息传递