检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

干燥温度对高水分小麦加工和应用品质的影响

中国粮油学报 2024年第7期39卷 52-61页

作者：翟静静张德鹏马清香牛兴和张连慧蒋沛格任晨刚马森河南工业大学粮油食品学院郑州450001 中粮营养健康研究院有限公司营养健康与食品安全北京市重点实验室老年营养食品研究北京市工程实验室北京102209 中粮面业(扬州)有限公司扬州225800 南京财经大学食品科学与工程学院、江苏省现代粮食流通与安全协同创新中心4 南京210023

为探究不同干燥温度对高水分小麦品质的影响,采用不同热风干燥温度(65、85、105、125℃)对初始水质量分数26%的小麦进行干燥处理,以未烘干小麦为对照,分析干燥对小麦加工及应用品质的影响。结果表明:热风干燥温度对高水分小麦品质影响显... 详细信息

为探究不同干燥温度对高水分小麦品质的影响,采用不同热风干燥温度(65、85、105、125℃)对初始水质量分数26%的小麦进行干燥处理,以未烘干小麦为对照,分析干燥对小麦加工及应用品质的影响。结果表明:热风干燥温度对高水分小麦品质影响显著,随热风温度升高,干燥后的小麦容重显著下降,裂纹率显著上升。在相同条件下制得的小麦粉,出粉率和灰分含量变化不大,破损淀粉有所下降,白度上升,粒径减小,溶剂保持力、沉淀指数降低,其中125℃下出粉率影响较大,破损淀粉含量和白度影响较小。与对照样品相比,65、85℃干燥对面筋含量和质量影响不大,面团的加工特性有所改善,馒头比容变化不大,硬度、黏性显著降低。当干燥温度为105℃和125℃时,湿面筋含量、形成时间、稳定时间显著下降,面团的操作性能降低,馒头比容和感官得分下降。对于制作馒头而言,26%水质量分数的小麦可采用不高于85℃的干燥温度。

关键词：小麦干燥高水分小麦热风干燥小麦品质馒头品质

基于气相-离子迁移谱分析结合感官分析鉴定不同品种小麦粉风味差异

在线全文

学校读者我要写书评

暂无评论

食品科技 2024年第1期49卷 129-137页

作者：强婉丽黄序郭子璇王鑫宇张连慧李沿伞惟琳营养健康与食品安全北京市重点实验室老年营养食品研究北京市工程实验室中粮营养健康研究院有限公司北京102209 中粮粮谷控股有限公司北京100020

为研究不同品种小麦粉的风味差异,对5个不同品种的小麦粉采用顶空萃取其挥发性物质并进行气相-离子迁移谱分析鉴定。结果表明:小麦粉中挥发性有机物共有48种,其中醇类16种、醛类9种、酮类7种、酯类11种、柠檬烯2种、二丙烯基硫化物1种... 详细信息

为研究不同品种小麦粉的风味差异,对5个不同品种的小麦粉采用顶空萃取其挥发性物质并进行气相-离子迁移谱分析鉴定。结果表明:小麦粉中挥发性有机物共有48种,其中醇类16种、醛类9种、酮类7种、酯类11种、柠檬烯2种、二丙烯基硫化物1种、酸类1种、呋喃类1种。不同品种小麦粉的挥发性有机物种类和浓度存在差异,XC样品中大部分挥发性物质含量略高于YL21,XM26和FDC大部分挥发性物质含量明显高于YL21,而SDXP与YL21相差不大。XC主要物质有:乙醇、2-丁酮、丁醇、环己烯-2-酮和二烯丙基硫化物等;SDXP主要物质有:丁酸乙酯、柠檬烯和己酸乙酯等;XM26主要物质有:甲基庚烯酮、壬醛、E-2-庚醛、反式-2-丁烯酸乙酯和2-甲基-3-呋喃硫醇等;FDC主要物质有:戊醛、丙酸乙酯、乙酸乙酯、丁醛、2-戊基呋喃和2-乙基-1-己醇等。通过感官定量描述性评分分析,发现不同品种小麦粉感官属性存在一定差异。根据相关性分析,挖掘并识别出小麦粉不同感官属性所代表的关键挥发性物质,初步建立关键物质含量与感官的相关性。

关键词：风味小麦粉感官分析气相-离子迁移谱挥发性物质

在线全文

学校读者我要写书评

暂无评论

弯曲乳杆菌与清酒乳杆菌的比较基因组学分析

食品科学 2024年第2期45卷 48-56页

作者：何苗赵雨晴李居行葛佳琪陈盼婷应欣张连慧王昌禄李贞景郭庆彬刘欢欢天津科技大学食品科学与工程学院天津300457 中粮营养健康研究院有限公司北京102209

本研究对19株弯曲乳杆菌(Latilactobacillus curvatus)和40株清酒乳杆菌(***)的基因组进行了比较分析。平均核苷酸同一性及全基因组共线性分析表明,***和***基因组间的核酸序列同源性较弱,可作为区分两个物种的指标。对两个物种分别构... 详细信息

本研究对19株弯曲乳杆菌(Latilactobacillus curvatus)和40株清酒乳杆菌(***)的基因组进行了比较分析。平均核苷酸同一性及全基因组共线性分析表明,***和***基因组间的核酸序列同源性较弱,可作为区分两个物种的指标。对两个物种分别构建泛基因组,并对泛基因组中的核心基因功能进行注释。结果显示,***和***各自的核心基因组主要涉及菌株的基础代谢。对菌株个体基因组的比对分析发现:1)***与***均含有广泛的糖苷水解酶类编码基因,在分解和代谢膳食纤维类多糖、乳糖利用以及木质纤维素中具有丰富的基因资源;2)3个菌株含抗生素耐药性基因,且来源于基因横向转移;3)***特有的精氨酸脱亚胺酶途径、***中的丝氨酸脱水酶途径及鸟嘌呤脱氨酶途径,以及个别菌株中谷氨酸脱羧酶的发掘,揭示了这两类菌不同的抗酸机制;4)冷应激蛋白编码基因的发现也赋予了这两类菌良好的冷加工特性。此外,部分***基因组中含有编码lactocin S及凝结素相关的基因簇。总之,本研究通过对***及***进行基因组水平的比较和分析,提供了两个物种之间的分类标准以及菌株个体上的差异信息,为这两种乳酸菌的生理生化分子遗传机制研究以及工业应用奠定了基础。

关键词：弯曲乳杆菌清酒乳杆菌基因组学泛基因组碳水化合物活性酶抗生素耐药性

The hierarchy quorum sensing networ in Pseudomonas aeruginosa

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2015年第1期6卷 26-41页

作者： Jasmine Lee lianhui zhang Institute of Molecular and Cell Biology Agency for Science Technology and Research Singapore Singapore Guangdong Province Key Laborato-ry of Microbial Signals and Disease Control College of Natural Resources and Environmental Sciences South China Agricultural University Guangzhou 510642 China

Pseudomonas aeruginosa causes severe and persistent infections in immune compromised individuals and cystic fibrosis sufferers. The infection is hard to eradi- cate as P. aeruginosa has developed strong resistance to most conventional antibiotics. The problem is further compounded by the ability of the pathogen to form biofilm matrix, which provides bacterial cells a protected environment withstanding various stresses including antibiotics. Quorum sensing （QS）, a cell density-based intercellular communication system, which plays a key role in regulation of the bacterial virulence and biofilm formation, could be a promising target for developing new strategies against P. aeruginosa infection. The QS network of P. aeruginosa is organized in a multi-layered hierarchy consisting of at least four interconnected signaling mechanisms. Evidence is accumulating that the QS regulatory network not only responds to bacte- rial population changes but also could react to envi- ronmental stress cues. This plasticity should be taken into consideration during exploration and development of anti-QS therapeutics.

关键词： quorum sensing IQS PQS las rhl,Pseudomonas aeruginosa virulence environmental factors

Polymorphisms of potential drug resistant molecular markers in Plasmodium vivax from China-Myanmar border during 2008-2017

在线全文

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2022年第2期11卷 93-94页

作者： Zhensheng Wang Chunyan Wei Yunchun Pan Zhihua Wang Xin Ji Qianqian Chen lianhui zhang Zenglei Wang Heng Wang Department of Microbiology and Parasitology Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical College5#Dong Dan San TiaoBeijing 100005People’s Republic of China NHC Key Laboratory of Systems Biology of Pathogens Institute of Pathogen BiologyChinese Academy of Medical Sciences and Peking Union Medical College9#Dong Dan San TiaoBeijingPeople’s Republic of China 不详

Background:Plasmodium vivax remains the predominant species at the China–Myanmar border,imposing a major challenge to the recent gains in regional malaria *** closely supervise the emerging of drug resistance in this area,we surveyed the variations in genes potentially correlated with drug resistance in *** parasite and the possible drug selection with ***:A total of 235 *** samples were collected from patients sufering uncomplicated malaria at Yingjiang,Tengchong,and Longling counties,and Nabang port in China,Yunnan province,and Laiza sub-township in Myanmar,from 2008 to *** potential drug resistance genes were amplifed utilizing nested-PCR and analyzed,including pvdhfr,pvdhps,pvmdr1,pvcrt-o,and *** Pearson’s Chi-squared test or Fisher’s exact test were applied to determine the statistical frequency diferences of mutations between categorical ***:The pvdhfr F57I/L,S58R,T61M and S117T/N presented in 40.6%,56.7%,40.1%,and 56.0% of the sequenced *** isolates,and these mutations signifcantly decreased with *** haplotype formed by these quadruple mutations predominated in Yingjiang,Tengchong,Longling and *** a mutation H99S/R(56.6%)dominated in Laiza and increased with *** pvdhps,the A383G prevailed in 69.2% of the samples,which remained the most prevalent ***,a signifcant decrease of its occurrence was also noticed over the *** S382A/C and A553G existed in 8.4% and 30.8% of the isolates,*** pvmdr1,the mutation Y976F occurred at a low frequency in 5/232(2.2%),while T958M was fxed and F1076L was approaching fxed(72.4%).The K10 insertion was detected at an occurrence of 33.2% in pvcrt-o,whereas there was no signifcant diference among the sites or over the *** mutation was identifed in ***:Mutations related with resistance to antifolate drugs are prevalent in this area,while their frequencies decrease signifcantly with time,suggestive of increased suscep

关键词： Plasmodium vivax Antimalarial drug Drug resistance Molecular marker China-Myanmar border

A heme-activatable probe and its application in the high-throughput screening of Plasmodium falciparum ring-stage inhibitors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第6期7卷 1882-1884页

作者： Sheng Liu Chunyan Wei Tian Liu Shuang-Gang Ma Chen Chen Hao Lin lianhui zhang Heng Wang Chong-Jing zhang Shi-Shan Yu State Key Laboratory of Bioactive Substance and Function of Natural Medicines and Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China Department of Microbiology and Parasitology Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical College5#Dong Dan San TiaoBeijing 100005China

Dear Editor,The resistance of Plasmodium falciparum to artemisinin derivatives(ARTs)in Asian,African and South American countries is a pressing global *** is an important biomarker of malaria parasites and is closely related to the mode of action of ARTs,but no heme-activatable fluorescent probe has been developed to study the biology of heme in malaria parasites in a light-up ***,we rationally developed probes from the unique reaction between heme and Yingzhaosu A(YZSA),then we unprecedentedly applied the probe to identify ring-stage inhibitors of ***.

关键词： falciparum heme Plasmodium

Cell division factor ZapE regulates Pseudomonas aeruginosa biofilm formation by impacting the pqs quorum sensing system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

mLife 2023年第1期2卷 28-42页

作者： Xi Liu Minlu Jia Jing Wang Hang Cheng Zhao Cai Zhaoxiao Yu Yang Liu Luyan ZMa lianhui zhang Yingdan zhang Liang Yang State Key Laboratory of Microbial Resources Institute of MicrobiologyChinese Academy of SciencesBeijingChina Key University Laboratory of Metabolism and Health of Guangdong School of MedicineSouthern University of Science and TechnologyShenzhenChina Guangdong Province Key Laboratory of Microbial Signals and Disease Control Integrative Microbiology Research CenterSouth China Agricultural UniversityGuangzhouChina Medical Research Center Southern University of Science and Technology HospitalShenzhenChina Shenzhen Third People's Hospital National Clinical Research Center for Infectious DiseaseThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhenChina

Pseudomonas aeruginosa is one of the leading nosocomial pathogens that causes both severe acute and chronic *** strong capacity of *** to form biofilms can dramatically increase its antibiotic resistance and lead to treatment *** biofilm resident bacterial cells display distinct gene expression profiles and phenotypes compared to their free-living *** the genetic determinants of biofilm formation is crucial for the development of antibiofilm *** this study,a highthroughput transposon-insertion site sequencing(Tn-seq)approach was employed to identify novel *** biofilm genetic *** analyzing the novel biofilm regulatory genes,we found that the cell division factor ZapE(PA4438)controls the *** pqs quorum sensing *** ΔzapE mutant lost fitness against the wild-type PAO1 strain in biofilms and its production of 2-heptyl-3-hydroxy-4(1H)-quinolone(PQS)had been *** biochemical analysis showed that ZapE interacts with PqsH,which encodes the synthase that converts 2-heptyl-4-quinolone(HHQ)to *** addition,site-directed mutagenesis of the ATPase active site of ZapE(K72A)abolished the positive regulation of ZapE on PQS *** ZapE is highly conserved among the Pseudomonas group,our study suggests that it is a potential drug target for the control of Pseudomonas infections.

关键词： biofilm Pseudomonas aeruginosa Pseudomonas quinolone signal transposon‐insertion site sequencing(Tn‐seq) ZapE

政绩、工分与农药:20世纪50—70年代中国的农药施用

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国经济史研究 2023年第4期 133-146页

作者：张连辉中南财经政法大学经济学院、经济史学研究中心武汉430073

通过专业化组织施用农药,有利于提高农药施用效率和保证用药安全,有助于实现经济效益和环境效益的统一。20世纪50—70年代,中国政府将建立稳定的基层专业化施药组织作为保证施药安全与效率的重要措施进行推广。农业集体化生产理应更有... 详细信息

通过专业化组织施用农药,有利于提高农药施用效率和保证用药安全,有助于实现经济效益和环境效益的统一。20世纪50—70年代,中国政府将建立稳定的基层专业化施药组织作为保证施药安全与效率的重要措施进行推广。农业集体化生产理应更有利于推进施药专业化,但在20世纪60年代至70年代前期,很多生产队的施药组织却长期不稳定。农村基本核算单位的频繁变动、平均主义收入分配方式、运动式防治方式、重产出的政绩考核体系和偏低的施药工分等,均在不同程度上影响了施药组织的稳定性。其中,重产出的政绩考核体系和偏低的施药工分应是关键原因。本研究表明,将技术性和危险性纳入分析后,劳动项目报酬设定或预设的合理性,会影响到生产队劳动力资源的配置效率及其生态环境表现。从农药污染防治角度来看,建立在评工记分基础上的收入分配和生产管理制度,总体上具有非环境友好特征。群众性施药组织的稳定性何以会在20世纪70年代后期得到增强,尚待进一步研究。

关键词：生产队农药专业化防治工分政绩

20世纪50—70年代中国农业病虫害“综合防治”理念的演进历程

在线全文

学校读者我要写书评

暂无评论

当代中国史研究 2022年第3期29卷 68-80,157,158页

作者：张连辉李进纬中南财经政法大学经济学院 430073

20世纪50年代初,新中国在推广应用化学农药的同时,提出病虫害“综合防治”理念,并将其付诸实践。到1980年,随着对化学防治及其生态环境效应认知的不断深化,中国“综合防治”理念逐步转变为“有害生物综合治理”理念。“预防为主,综合防... 详细信息

20世纪50年代初,新中国在推广应用化学农药的同时,提出病虫害“综合防治”理念,并将其付诸实践。到1980年,随着对化学防治及其生态环境效应认知的不断深化,中国“综合防治”理念逐步转变为“有害生物综合治理”理念。“预防为主,综合防治”方针的确立,有力推动了政策层面的“综合防治”内涵向“有害生物综合治理”转变。20世纪50—70年代是以化学防治为主的植保格局的形成期,但并非是以化学防治为主的典型阶段。从系统论出发统筹开展研究,着力补齐相关研究中的短板,对政策方针的完善及其实践效果的改善具有重要意义。

关键词：综合防治植保方针农药污染 IPM