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China CDC weekly 2024年第5期6卷 77-82,I0002-I0005页

作者： Huiyun Chang Mingjun Li Ying Wang liangliang cui Tiantian Li Jinan Municipal Center for Disease Control and Prevention Jinan Municipal Center for Disease Control and Prevention Affiliated to Shandong UniversityJinan CityShandong ProvinceChina Chinese Filed Epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?The mortality rate due to pneumonia varies depending on the infectious agents present in a low-temperature environment.What is added by this report?This study aimed to examine the relationship between low temperatures and cold waves and the risk of mortality from infectious pneumonia in the elderly.The findings indicate a significant increase in the risk of infectious pneumonia.

关键词： environment Shandong finding

The Combined Effects of High Temperatures and Ozone Pollution on Medical Emergency Calls—Jinan City,Shandong Province,China,2013–2019

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China CDC weekly 2024年第2期6卷 30-35,I0001-I0007页

作者： Huiyun Chang Chong Liu Xingyi Geng Xiumiao Peng Ke Huang Liheng Wang liangliang cui Department of Scientific Research and Education Jinan Municipal Center for Disease Control and PreventionJinan Municipal Center for Disease Control and Prevention Affiliated to Shandong UniversityJinan CityShandong ProvinceChina Jinan Health Well Development Center Jinan CityShandong ProvinceChina Department of Environmental Health Jinan Municipal Center for Disease Control and PreventionJinan CityShandong ProvinceChina Department of Emergency Jinan Medical Emergency CenterJinan CityShandong ProvinceChina

What is already known about this topic?Studies have extensively documented the separate and independent effects of extreme temperature and ozone on morbidity and mortality associated with respiratory and circulatory diseases.What is added by this report?The study revealed a significant association between elevated temperature,ozone pollution,and the combined effect of high temperature and ozone pollution with an increased risk of all-cause medical emergency calls(MECs)and MECs specifically related to neurological diseases.What are the implications for public health practice?Interventional measures should be implemented to mitigate exposure to high temperatures and ozone levels.Specifically,during the warm season,it is crucial for relevant authorities to focus on disseminating scientific information regarding the health impacts of elevated temperatures and ozone pollution.Additionally,timely public health advisories should be issued to alert the public effectively.

关键词： ozone elevated pollution

Evaluating the Applicability and Health Benefits of the Graded Heat Health Risk Early Warning Model-Jinan City,Shandong Province,China,2022

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China CDC weekly 2023年第29期5卷 642-646,I0001-I0003页

作者： Chen Chen Jing Liu Menghan Wang liangliang cui Tiantian Li China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina Key Laboratory of Public Health Safety of Hebei Province College of Public HealthHebei UniversityBaoding CityHebei ProvinceChina Department of Environmental Health Jinan Center for Disease Control and PreventionJinan CityShandong ProvinceChina

What is already known about this topic?The heat health early warning model serves as an effective strategy for reducing health risks related to heatwaves and improving population adaptability.Several high-income countries have taken the lead in conducting research and implementing measures aimed at safeguarding their populations.What is added by this report?The graded heat health risk early warning model(GHREWM)in Jinan City has demonstrated efficacy in safeguarding males,females,individuals aged above 75 years,and those with cardiopulmonary diseases.During the summer of 2022,the warning stage of GHREWM contributed to the prevention of 10.9 deaths per million individuals,concurrently averting health-related economic losses estimated at approximately 227 million Chinese Yuan(CNY).What are the implications for public health practice?The GHREWM has the potential to enhance cities’adaptability to climate change.It is crucial to incorporate additional adverse health endpoint data in the development of early warning models,as this will improve their applicability and protective efficacy.

关键词： income conducting measures

济南市2013―2019年大气臭氧暴露对居民超额应急呼叫的风险评估

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中华疾病控制杂志 2024年第4期28卷 479-485页

作者：常会云王丽珩黄珂李明君崔亮亮济南市疾病预防控制中心科研教育部济南250021 济南市疾病预防控制中心环境健康所济南250021 济南市急救中心急救部济南250021

目的探讨济南市2013―2019年臭氧(Ozone,O_(3))暴露对居民超额应急呼叫风险的影响。方法收集济南市2013―2019年每日的居民应急呼叫事件信息,以及同期每日的空气污染物(O_(3)、PM_(2.5)、PM_(10)、NO_(2)、SO_(2)、CO)浓度和气象因素(... 详细信息

目的探讨济南市2013―2019年臭氧(Ozone,O_(3))暴露对居民超额应急呼叫风险的影响。方法收集济南市2013―2019年每日的居民应急呼叫事件信息,以及同期每日的空气污染物(O_(3)、PM_(2.5)、PM_(10)、NO_(2)、SO_(2)、CO)浓度和气象因素(日均温度、日均相对湿度和日均风速)资料,采用病例交叉设计方法确定暴露-反应系数,Cox比例风险回归模型进行健康风险评估;对呼吸、循环和神经系统疾病进行分层分析,同时比较冬春季和夏秋季O_(3)暴露造成的超额应急呼叫风险是否具有差异。结果2013―2019年济南市共发生应急呼叫事件653473件,平均每日应急呼叫总量为250人次。通过总应急呼叫的影响效应分析和超额风险评估发现,O_(3)浓度每升高10μg/m3,居民总应急呼叫的风险增加0.375%(95%CI:0.288%~0.461%),造成的超额应急呼叫总量为7226人次。疾病分层分析发现,研究期间O_(3)暴露仅对增加神经系统疾病应急呼叫的超额风险差异有统计学意义(P冬春季。结论济南市O_(3)暴露增加居民的超额应急呼叫风险,且夏秋季O_(3)暴露造成的超额应急呼叫风险高于冬春季,特别是神经系统疾病受其影响更为显著。

关键词：臭氧应急呼叫风险评估

2017-2022年济南市中暑流行特征及与热浪的潜在关联

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环境与职业医学 2024年第4期41卷 384-389页

作者：常会云单冰彭秀苗李湉湉崔亮亮中国疾病预防控制中心中国现场流行病学培训项目北京100050 济南市疾病预防控制中心科研教育部山东济南250021 济南市疾病预防控制中心环境健康所山东济南250021 中国疾病预防控制中心环境与健康相关产品安全所北京100021 济南市精神卫生中心山东济南250309

[背景]近年来中国夏季区域性高温天气频繁出现,中暑是高温所导致的代表性气象病。分析中暑流行特征及热浪暴露对其影响,对做好中暑的监测、预警和防控工作具有重要意义。[目的]了解济南市中暑病例的流行病学特征,探讨热浪暴露对中暑的... 详细信息

[背景]近年来中国夏季区域性高温天气频繁出现,中暑是高温所导致的代表性气象病。分析中暑流行特征及热浪暴露对其影响,对做好中暑的监测、预警和防控工作具有重要意义。[目的]了解济南市中暑病例的流行病学特征,探讨热浪暴露对中暑的影响。收集2017-2022年济南市中暑病例的个案信息以及同期逐日的气象因素数据,描述济南市中暑病例的发生时间、人群和地区分布特征,采用时间分层的病例交叉设计并结合条件logistic回归模型,探索12种热浪定义(不同强度和持续时间组合)下热浪暴露对中暑的影响。其中,热浪强度分别使用研究期间日均温度的第90百分位数(P_(90))和P_(95)、P_(97.5)、P_(99)表示,持续时间包括≥2 d、≥3 d、≥4 d,记为Pi(k),i为温度阈值,k为持续时间,如P90(2)即表示连续至少2 d的日均温度大于等于研究期间日均温度的第90百分位数对应的温度值。以lag01表示滞后1 d的累积滞后效应,以此类推。[结果]2017-2022年济南市共报告中暑病例1394例,轻症患者581例,重症患者813例;累积报告死亡85例,累积病死率为6.10%。流行特征分析结果显示:研究期间报告的中暑病例集中分布于6-8月,且在7月出现高峰(665例,47.70%);中暑病例中男女性别比为2.02:1,病例的高发年龄段为50~89岁,且在70~79岁组和50~59岁组出现两次高峰,但最高峰出现在70~79岁;病例高发地区分布于济南市西部的中心城区(天桥区,274例,19.66%;槐荫区,223例,16.00%)和周边农村地区(平阴县,254例,18.22%)。热浪暴露影响效应分析结果显示,热浪暴露对中暑的影响具有统计学意义。对中暑影响的最大效应估计值分别出现在P_(99)(2)、P_(97.5)(3)和P_(97.5)(4)定义下的lag04、lag03、lag04,OR(95%CI)分别为9.27(4.71~14.24)、8.95(6.17~12.98)和8.22(4.91~13.78)。暴露-反应关系曲线提示,随着日均温度的升高,中暑风险呈上升趋势。[结论]每年7月是济南市居民中暑的高发时期,同时以男性病例为主,重症多,年龄集中在50~89岁。热浪的发生可进一步增加中暑的风险,且存在显著的滞后效应。

关键词：高温热浪中暑流行病学特征病例交叉济南市

神经重症患者目标体温管理认知现状及培训需求调查

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卫生职业教育 2024年第11期42卷 134-137页

作者：张丹崔亮亮文丹绵阳市中心医院四川绵阳621000

目的了解护士对神经重症患者目标体温管理的认知现状及培训需求。方法选取四川省绵阳市重症护理专业委员会12家医疗机构的ICU及神经内外科护士进行调查。结果知道目标体温管理、亚低温治疗或治疗性低温的护士分别占24.1%、29.1%;最... 详细信息

目的了解护士对神经重症患者目标体温管理的认知现状及培训需求。方法选取四川省绵阳市重症护理专业委员会12家医疗机构的ICU及神经内外科护士进行调查。结果知道目标体温管理、亚低温治疗或治疗性低温的护士分别占24.1%、29.1%;最常选择的体温监测部位是体表(包括腋温、额温、耳温),其次为直肠;最常用的目标体温管理方式为冰毯、冰帽,其次为冰袋、电扇或空调等体表降温;91.1%的护士认为应对全体医护人员进行目标体温管理培训,目标体温基础知识、循证相关知识、操作知识是护士关注的培训内容。结论护士目标体温管理不论是在认知还是实践方面都存在不足,今后应对全体医护人员进行目标体温管理培训。

关键词：目标体温管理神经重症亚低温护理人员

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PM_(2.5)成分与室内因素对儿童肺功能影响的交互作用研究

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黑龙江环境通报 2024年第6期37卷 10-13页

作者：左鹏程凤志慧崔亮亮山东大学公共卫生学院济南250000 济南市疾病预防控制中心济南250021

探索济南市历城区王舍人实验小学PM_(2.5)组成成分与室内因素对儿童肺功能影响的交互作用,为改善儿童呼吸系统健康提供理论依据。在2020年王舍人实验小学教学楼二楼楼顶进行PM_(2.5)采样,为期75d,并分析PM_(2.5)的主要成分,对3~5年级13... 详细信息

探索济南市历城区王舍人实验小学PM_(2.5)组成成分与室内因素对儿童肺功能影响的交互作用,为改善儿童呼吸系统健康提供理论依据。在2020年王舍人实验小学教学楼二楼楼顶进行PM_(2.5)采样,为期75d,并分析PM_(2.5)的主要成分,对3~5年级139名儿童进行肺功能的检测与室内因素相关的问卷调查,利用混合效应模型检测影响儿童呼吸健康的交互作用因素。济南市历城区采样点PM_(2.5)平均浓度62.74μg/m^(3),主要成分包括SO_(4)^(2-)·NO_(3)^(-),各类金属元素和多环芳烃化合物,与上述成分对儿童呼吸系统健康产生交互作用的因素主要包括环境烟草烟雾,装修,环境相关化学品等危险因素,还存在空气净化器和口罩佩戴等保护性因素。在环境污染较重的区域注重室内因素有利于提高儿童肺功能。

关键词： PM_(2.5)成分室内因素儿童肺功能

基于DLNM模型评估大气污染物对济南市2015-2019年流感样病例发病影响

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国际病毒学杂志 2024年第1期31卷 58-62页

作者：吴善正崔亮亮于秋燕马若群周成超常彩云山东大学齐鲁医学院公共卫生学院卫生管理与政策研究中心、国家卫生健康委员会卫生经济与政策研究重点实验室济南250012 济南市疾病预防控制中心传染病防制所 250021

目的探讨2015-2019年济南市大气污染物与流感样病例发病之间的关系,为流感预警提供科学依据.方法本研究收集了2015-2019年济南市流感样病例、气象及大气污染物数据,对流感样病例的流行概况进行描述.采用R 4.2.2软件进行spearman相关性分... 详细信息

目的探讨2015-2019年济南市大气污染物与流感样病例发病之间的关系,为流感预警提供科学依据.方法本研究收集了2015-2019年济南市流感样病例、气象及大气污染物数据,对流感样病例的流行概况进行描述.采用R 4.2.2软件进行spearman相关性分析,并构建分布滞后非线性模型(distributed lag non-linear model,DLNM)以探索大气污染物与流感样病例发病的关联.结果济南市5所国家级流感哨点医院共报告156699例流感样病例.济南市大气污染物与流感样病例发病存在相关性,并有滞后效应.在特定浓度下,PM_(2.5)、SO_(2)、NO_(2)、O_(3)具有统计学意义的累积滞后效应最大值分别为1.134(95%CI:1.018~1.263),1.291(95%CI:1.055~1.580),1.341(95%CI:1.229~1.462),1.267(95%CI:1.085~1.481),且大气污染物的累积滞后效应大于单日滞后效应.结论大气污染物会导致济南市流感样病例发病风险增加.建议相关部门加强大气污染物的预报工作,应在污染天气及时提醒公众采取适当的防护措施.

关键词：流感样病例分布滞后非线性模型大气污染物环境因素

PM_(2.5) exposure associated with microbiota gut-brain axis:Multi-omics mechanistic implications from the BAPE study

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The Innovation 2022年第2期3卷 110-118页

作者： Tiantian Li Jianlong Fang Song Tang Hang Du Liang Zhao Yanwen Wang Fuchang Deng Yuanyuan Liu Yanjun Du liangliang cui Wanying Shi Yan Wang Jiaonan Wang Yingjian Zhang Xiaoyan Dong Ying Gao Yu Shen Li Dong Huichan Zhou Qinghua Sun Haoran Dong Xiumiao Peng Yi Zhang Meng Cao Hong Zhi Jingyang Zhou Xiaoming Shi China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing 100021China Jinan Municipal Center for Disease Control and Prevention JinanShandong 250021China Shandong Provincial Center for Disease Control and Prevention JinanShandong 250014China

Recent studies have shown that PM_(2.5) may activate the hypothalamus-pituitary-adrenal(HPA)axis by inducing hormonal changes,potentially explaining the increase in neurological and cardiovascular risks.In addition,an association between PM_(2.5) and gut microbiota and metabolites was established.The above evidence represents crucial parts of the gut-brain axis(GBA).In view of this evidence.

关键词： exposure explain PM

A Bibliometric Analysis Unveils Valuable Insights into the Past,Present,and Future Dynamics of Plant Acclimation to Temperature

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Phyton-International Journal of Experimental Botany 2024年第2期93卷 291-312页

作者： Yong cui Yongju Zhao Shengnan Ouyang Changchang Shao liangliang Li Honglang Duan Institute for Forest Resources&Environment of Guizhou Key Laboratory of Forest Cultivation in Plateau Mountain of Guizhou ProvinceCollege of ForestryGuizhou UniversityGuiyangChina

Plant temperature acclimation is closely related to maintaining a positive carbon gain under future climate change.However,no systematic summary of the field has been conducted.Based on this,we analyzed data on plant temperature acclimation from the Web of Science Core Collection database using bibliometric software R,RStudio and VOSviewer.Our study demonstrated that a stabilized upward trajectory was noted in publications(298 papers)from 1986 to 2011,followed by a swift growth(373 papers)from 2012 to 2022.The most impactful journals were Plant Cell and Environment,boasting the greatest count of worldwide citations and articles,the highest H-index and G-index,followed by Global Change Biology and New Phytologist,and Frontiers in Plant Science which had the highest M-index.The USA and China were identified as the most influential countries,while Atkin was the most influential author,and the Chinese Academy of Sciences was the most influential research institution.The most cited articles were published in the Annual Review of Plant Biology in 1999.“Cold acclimation”was the most prominent keyword.Future plant temperature acclimation research is expected to focus on thermal acclimation and photosynthesis,which have important significance for future agricultural production,forestry carbon sequestration,and global food security.In general,this study provides a systematic insight of the advancement,trend,and future of plant temperature acclimation research,enhancing the comprehension of how plants will deal with forthcoming climate change.

关键词： Temperature acclimation plant responses climate change bibliometric