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Multiframe track-before-detect method based on velocity filtering in mixed coordinates

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Journal of Systems Engineering and Electronics 2022年第2期33卷 247-258页

作者： wang liangliang ZHOU Gongjian School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin 150001China Key Laboratory of Marine Environmental Monitoring and Information Processing Ministry of Industry and Information TechnologyHarbin 150001China

In this paper,a velocity filtering based track-before-detect algorithm in mixed coordinates is presented to address the problem of integration loss caused by inaccurate motion model in polar coordinate *** the motion of a con-stant velocity(CV)target is better modeled in Cartesian coordi-nates,the search of measurements for integration in polar sensor coordinates is carried out according to the CV model in Cartesian coordinates instead of an approximate model in polar sensor *** position of each cell is converted into Cartesian coordinates and predicted according to an assumed ***,the predicted Cartesian position is converted back to polar sensor coordinates for multiframe *** use of the correct model improves integration effectiveness and consequently improves algorithm *** handle the weak target with unknown velocity,a velocity filter bank in mixed coordinates is *** influence of velocity mis-match on the performance of filter bank is analyzed,and an effi-cient strategy for filter bank design is *** re-sults are presented to demonstrate the effectiveness of the pro-posed algorithm.

关键词： mixed coordinate approach velocity filtering multiframe integration weak target detection polar sensor coordinate

Multiframe weak target track-before-detect based on pseudo-spectrum in mixed coordinates

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Chinese Journal of Aeronautics 2022年第5期35卷 97-113页

作者： liangliang wang Gongjian ZHOU Thiagalingam KIRUBARAJAN School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin 150001China Key Laboratory of Marine Environmental Monitoring and Information Processing Ministry of Industry and Information TechnologyHarbin 150001China Department of Electrical and Computer Engineering McMaster UniversityONHamilton L8S 4K1Canada

Traditional multiframe Track-Before-Detect(TBD)may incur adverse integration loss resulting from model mismatch in sensor *** suboptimal integration strategy may cause target envelope *** address these issues,a pseudo-spectrum-based multiframe TBD in mixed coordinates is proposed *** data search for energy integration is conducted based on an accurate model in the x-y plane while target energy is integrated based on pseudo-spectrum in sensor *** algorithm performance is improved since the model mismatch is eliminated,and the pseudo-spectrum based integration facilitates well maintained target *** detailed multiframe integration procedure and theoretical target integrated envelope are ***,to cope with the unknown target velocity,a velocity filter bank based on pseudo-spectrum in mixed coordinates is *** effect of velocity mismatch on algorithm performance is analyzed and an efficient method for filter bank design is ***,a parameter estimation method using characteristics of integrated envelope is presented for improved target polar position and Cartesian velocity ***,numerical results are provided to demonstrate the effectiveness of the proposed method.

关键词： Mixed coordinates Multiframe detection Pseudo-spectrum Track-before-detect Weak target detection

An efficient pairing-free certificateless signature scheme for resource-limited systems

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Science China(Information Sciences) 2017年第11期60卷 291-293页

作者： liangliang wang Kefei CHEN Yu LONG Huige wang College of Computer Science and Technology Shanghai University of Electric Power Laboratory of Science and Technology on Communication Security School of Science Hangzhou Normal University Department of Computer Science and Engineering Shanghai Jiao Tong University

Dear editor,As certificateless public key cryptography(CLPKC)[1]is proposed,a number of certificateless public key signature(CL-PKS)schemes[2–6]have been *** to various construction methods,we divide them into three types:pairing-based CL-PKS schemes,elliptic curve cryptography-based(ECC-based)pairingfree CL-PKS schemes and general pairing-free CLPKS schemes(see Appendix A in the supporting information).On account of the high cost of bilinear pairings operations,pairing-based CLPKS schemes are not good choices for resourcelimited *** systems cannot execute complex applications very well due to the limi-

关键词： PKS An efficient pairing-free certificateless signature scheme for resource-limited systems ID

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An approach to study interactions of antineutrons with Csl at a J/ψfactory

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Radiation Detection Technology and Methods 2024年第3期8卷 1405-1412页

作者： Sicheng Yuan liangliang wang Weidong Li Institute of High Energy Physics Chinese Academy of SciencesBeijing100049China University of Chinese Academy of Sciences Beijing100049China

Purpose Cesium iodide(CsI)crystals are widely used in high-energy physics for their scintillation properties that enable detection of charged and neutral particles via direct and indirect ionization and form the basis of electromagnetic ***,knowledge of antineutron interactions with CsI is limited due to the difficulty of obtaining antineutron sources in sufficient intensity and wide energy *** antineutron are abundantly produced by many physics process,it would be particularly useful to improve understanding of the interactions of antineutrons with CsI *** We propose to use decay of J/ψ→pπ-n a J/ψat a factory as a source of antineutrons and a CsI target added between the beam pipe and the detector to study such *** use Monte Carlo simulation at the BESIII experiment as a proof of the *** simulation with varying thicknesses of CsI target is performed to validate the approach and optimize the target *** and conclusions Selecting charged particle tracks(p and n^(-))from the Monte Carlo sample,we obtain clean antineutron samples with well defined momentum and *** selection efficiency,momentum and angular resolutions,as well as the interaction probability between antineutron and the CsI target are *** the CsI thickness is increased more antineutron-CsI interactions are obtained,however the quality of the part selection is *** Monte Carlo study yields an optimum thickness that balances these *** approach can be applied to similar experiments with other types of target materials such as liquid hydrogen/deuterium and other baryons such as and■.

关键词： Antineutron-Cesium iodide Calorimeter J/ψdecays

Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends

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Signal Transduction and Targeted Therapy 2023年第9期8卷 4188-4213页

作者： Qian Sun Zhenya Hong Cong Zhang liangliang wang Zhiqiang Han Ding Ma Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Cancer Biology Research Center(Key Laboratory of the Ministry of Education) Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China

Immune-checkpoint inhibitors(ICBs),in addition to targeting CTLA-4,PD-1,and PD-L1,novel targeting LAG-3 drugs have also been approved in clinical *** the widespread use of the drug,we must deeply analyze the dilemma of the agents and seek a breakthrough in the treatment *** the past decades,these agents have demonstrated dramatic efficacy,especially in patients with melanoma and non-small cell lung cancer(NSCLC).Nonetheless,in the field of a broad concept of solid tumours,non-specific indications,inseparable immune response and side effects,unconfirmed progressive disease,and complex regulatory networks of immune resistance are four barriers that limit its widespread ***,the successful clinical trials of novel ICB agents and combination therapies,the advent of the era of oncolytic virus gene editing,and the breakthrough of the technical barriers of mRNA vaccines and nano-delivery systems have made remarkable breakthroughs *** this review,we enumerate the mechanisms of each immune checkpoint targets,associations between ICB with tumour mutation burden,key immune regulatory or resistance signalling pathways,the specific clinical evidence of the efficacy of classical targets and new targets among different tumour types and put forward dialectical thoughts on drug ***,we discuss the importance of accurate triage of ICB based on recent advances in predictive biomarkers and diagnostic testing techniques.

关键词： clinical breakthrough dilemma

An iterative weighting method to apply ISR correction to e+e−hadronic cross-section measurements

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Frontiers of physics 2021年第6期16卷 93-98页

作者： Wenyu Sun Tong Liu Maoqiang Jing liangliang wang Bin Zhong Weimin Song College of Physics Jilin UniversityChangchun 130012China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Department of Physics Nanjing Normal UniversityNanjing 210023China

Initial State Radiation(ISR)plays an important role in e+e−collision experiments such as the *** correct the ISR effects in measurements of hadronic cross-sections of e+e−annihilation,an iterative method that weights simulated ISR events is proposed here to assess the efficiency of event selection and the ISR correction factor for the observed *** simulated ISR events were generated only once,and the obtained cross-sectional line shape was used iteratively to weigh the same simulated ISR events to evaluate the efficiency and corrections until the results *** with the method of generating ISR events iteratively,the proposed weighting method provides consistent results,and reduces the computational time and disk space required by a factor of five or more,thus speeding-up e+e−hadronic cross-section measurements.

关键词： Initial State Radiation(ISR) iteration Monte Carlo weighting

Numerical simulation and experimental validation of gas–solid flow in the riser of a dense fluidized bed reactor

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Particuology 2009年第4期7卷 278-282页

作者： Xueyao wang Fan Jiang xiang xu Shengdian wang Xuezhi Wu Baoguo Fan liangliang Liao Jiachang wang Yunhan Xiao Key Laboratory of Advanced Energy and Power. Institute of Engineering Thermophysics Chinese Academy of Sciences Beijing 100190 China

Gas-solid flow in the riser of a dense fluidized bed using Geldart B particles （sand）, at high gas velocity （7.6-15.5 m/s）s） and with comparatively high solid flux （140-333.8 kg]m^2 s）, was investigated experimentally and simulated by computational fluid dynamics （CFD）, both two- and three-dimensional and using the Gidaspow, O＇Brien-Syamlal, Koch-Hill-Ladd and EMMS drag models, The results predicted by EMMS drag model showed the best agreement with experimental results. Calculated axial solids hold-up profiles, in particular, are well consistent with experimental data. The flow structure in the riser was well represented by the CFD results, which also indicated the cause of cluster formation. Complex hydrody-namical behaviors of particle cluster were observed. The relative motion between gas and solid phases and axial heterogeneity in the three subzones of the riser were also investigated, and were found to be consistent with predicted flow structure. The model could well depict the difference between the two exit configurations used, viz., semi-bend smooth exit and T-shaped abrupt exit. The numerical results indicate that the proposed EMMS method gives better agreement with the experimental results as compared with the Gidaspow, O＇Brien-Syamlal, Koch-Hill-Ladd models. As a result, the proposed drag force model can be used as an efficient aporoach for the dense zas-solid two-ohase flow.

关键词： Gas-solid flow Drag model EMMS Exit configuration

Application of acid protease in the industrial production of corn ethanol

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Systems Microbiology and Biomanufacturing 2022年第2期2卷 361-368页

作者： liangliang wang Qi Yao Jun Yue Xirui Jiang Fangfang Li Linyi Jiayun Biotechnology Co. LTDLinyi 273306ShandongChina Research Institute of Jilin Petrochemical Co. LTDPetroChinaJilin 132021JilinChina Wuxi Jiangda Yizhong Biological Engineering Co. LTDWuxi 214062JiangsuChina School of Food Science and Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353ShandongChina

Bioethanol is a renewable,clean energy and a very important basic chemical raw material,improving production efciency and reducing production cost are the goals pursued by ethanol *** acid protease in the process of producing ethanol from grain will have many efects on fermentation,one of the most concerned efects is to increase liquor *** protease can hydrolyze the protein in cereals to produce free amino acids that can be used directly by yeast,thus reducing the amount of sugar consumed for amino acid metabolism,and allowing more sugar to be converted to *** application method and efect of acid protease in the industrial production of ethanol from corn were studied in this study,the results showed that the addition of acid protease at the dosage of 10 U/g(raw material)during yeast seeding could replace urea,promote yeast proliferation,reduce the infection rate,shorten the fermentation period by 7.5 h and increase the alcohol yield of raw materials by 0.33 percentage *** acid protease was used in ethanol production line with an annual output of 180,000 tons,the net proft increased by at least US$4900/day compared with the control *** is hoped that this study can lay a foundation for the application of acid protease in ethanol industry.

关键词： Acid protease Ethanol Corn Application Industrial production

Industrialization progress of lignocellulosic ethanol

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Systems Microbiology and Biomanufacturing 2022年第2期2卷 246-258页

作者： liangliang wang Muhammad Bilal Congping Tan Xirui Jiang Fangfang Li Linyi Jiayun Biotechnology Co. Ltd.Linyi 273306ShandongChina Department of Biological Chemical Engineering College of Chemical Engineering and Materials ScienceTianjin University of Science and TechnologyTianjin 300457China College of Biotechnology Tianjin University of Science and TechnologyTianjin 300457China School of Food Science and Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353ShandongChina Wuxi JiangdaYizhong Biological Engineering Co. Ltd.Wuxi 214062JiangsuChina

Lignocellulose is an abundant and renewable biomass that is mainly composed of cellulose,hemicellulose and *** development and utilization of lignocellulosic ethanol is an efective way to solve the energy problem/crises,In addition,lignocellulosic ethanol industry can play a signifcant role in controlling environmental pollution and extending agricultural industrial chain;however,it has not been able to realize large-scale industrialization due to the limitation of both biotechnology and *** review frst introduces industrialization status of lignocellulosic ethanol,and then focuses on the progress of practical technology and analyzing the economic feasibility of the second-generation bioethanol plant;fnally,the future development trend of the industry was *** summarize,continuous technological innovation is needed in vital steps such as pretreatment,enzymatic hydrolysis,and ***,for making the cellulosic ethanol industry truly economically competitive,we also need to achieve interdisciplinary,cross-domain integration innovation,such as the construction of raw material collection and storage system,in situ producing special enzyme system,high-value utilization of raw material components,developing a closely integration of biomass refnery with mature equipment and overall industrialization programs,*** is hoped that this review can provide a useful reference for the industrialization of second-generation bioethanol.

关键词： Lignocellulosic ethanol Industrialization Technology Economic analysis