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Thin-film growth behavior of non-planar vanadium oxide phthalocyanine

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Chinese Physics B 2019年第8期28卷 369-375页

作者： Tian-Jiao Liu Hua-Yan Xia Biao Liu Mei Fang jun-liang yang Hunan Key Laboratory for Super-microstructure and Ultrafast Process School of Physics and ElectronicsCentral South UniversityChangsha 410083China Department of Chemistry University of WarwickCoventryCV47ALUnited Kinedom

The thin film properties of organic semiconductors are very important to the device ***,non-planar vanadyl phthalocyanine(VOPc)thin films grown on rigid substrates of indium tin oxide,silicon dioxide,and flexible substrate of kapton by organic molecular beam deposition under vacuum conditions are systematically studied via atomic force microscopy and x-ray *** results clearly reveal that the morphology and grain size are strongly dependent on the substrate temperature during the process of film ***,the VOPc films with the structure of phase I or phase II can be modulated via in situ annealing and post-annealing ***,the crystalline structure and molecular orientation of vapor-deposited VOPc can be controlled using molecular template layer 3,4,9,10-perylenetetracarboxylic dianhydride(PTCDA),the VOPc film of which exhibits the phase I *** deep understanding of growth mechanism of non-planar VOPc film provides valuable information for controlling structure-property relationship and accelerates the application in electronic and optoelectronic devices.

关键词： organic semiconductor thin film vanadyl phthalocyanine(VOPc) growth behavior

Curcumin for gastric cancer:Mechanism prediction via network pharmacology,docking,and in vitro experiments

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3635-3650页

作者： Peng-Hui yang Ya-Nan Wei Bi-Juan Xiao Si-Yi Li Xin-Long Li liang-jun yang Hua-Feng Pan Geng-Xin Chen The Second School of Clinical Medicine Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Department of Traditional Chinese Medicine The People's Hospital of LonghuaShenzhen 518109Guangdong ProvinceChina Department of Gastroenterology Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Centre for Translational Medicine The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Curcumin originates from the natural herb turmeric,and its antitumor effects have been known about for a long ***,the mechanism by which curcumin affects gastric cancer(GC)has not been *** To elucidate the potential mechanisms of curcumin in the treatment of *** Network pharmacological approaches were used to perform network analysis of *** first analyzed Lipinski’s Rule of Five for the use of *** latent targets were predicted using the PharmMapper,SwissTargetPrediction and DrugBank network *** disease targets were mined through the GeneCard,OMIM,DrugBank and TTD network ***,GO enrichment,KEGG enrichment,protein-protein interaction(PPI),and overall survival analyses were *** results were further verified through molecular docking,differential expression analysis and cell *** We identified a total of 48 curcumin-related genes with 31 overlapping GC-related *** intersection targets between curcumin and GC have been enriched in 81 GO biological processes and 22 significant *** PPI analysis,6 hub targets were identified,namely,estrogen receptor 1(ESR1),epidermal growth factor receptor(EGFR),cytochrome P450 family 3 subfamily A member 4(CYP3A4),mitogen-activated protein kinase 14(MAPK-14),cytochrome P450 family 1 subfamily A member 2(CYP1A2),and cytochrome p450 family 2 subfamily B member 6(CYP2B6).These factors are correlated with decreased survival rates among patients diagnosed with *** docking analysis further substantiated the strong binding interactions between Curcumin and the hub target *** experimental findings demonstrated that curcumin not only effectively inhibits the growth of BGC-823 cells but also suppresses their *** levels of hub targets CYP3A4,MAPK14,CYP1A2,and CYP2B6 in BGC-823 cells were significantly increased in each dose *** Curcumin can play an anti-GC role through a variety of

关键词： Curcumin Gastric cancer Network pharmacology Molecular docking Survival analysis

Research on Form Innovation Design and Implementation of Secondary Reconstruction for Cool Core Fabric

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International Journal of Technology Management 2015年第9期 17-19页

作者： jun liang Yueming yang School of Art Northeast Dianli University JilinChina

In this paper, we conduct theoretical analysis and literature review applications on the form innovation design and implementation of secondary reconstruction for cool core fabric. At present, due to the development of The Times and the progress of science and technology, people＇ s aesthetic concept also transformed, functional and decorative fabric art aesthetic has been raised to an important level, but also strong. Second fabric design is refers to the use of various traditional and high-tech means to the existing fabric to open out the design of the processing, make its surface rich visual texture and touch skin texture. Our method is effective and novel, we will try to make it into real-world applications in the future.

关键词： Cool Core Fabric Secondary Design and Implementation Reconstruction Procedure.

Identification of key pathways and genes from gastric precancerous lesions to gastric cancer by integrated bioinformatics analysis

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TMR Cancer 2020年第1期3卷 32-43页

作者： liang-jun yang Jing Li Chi Zhang Yue-jun Li Guangzhou University of Chinese Medicine Guangzhou 510405China The First Affiliated Hospital of Hunan University of Chinese Medicine Changsha 410007China Zhuzhou Hospital of Traditional Chinese Medicine Zhuzhou 412008China

Objective:This work aimed to illuminate the potential key genes and pathways in GC tumorigenesis based on bioinfOrmatics ***:The differentially expressed genes(DEGs)between GPL tissue samples and GC tissue samples were investigated using the GSE55696 and GSE87666 microarray data from the Gene Expression Omnibus(GEO)*** were identified by an empirical Bayes method based on the Limma R ***,KEGG and GO enrichment analyses of DEGs were performed followed by protein-protein interaction(PPI)network ***,the overall survival(OS)analysis of key genes was performed by the Kaplan-Meier plotter online ***:A total of 250 DEGs were obtained,of which 216 were up-regulated and 34 were *** pathways analysis showed that the up-regulated DEGs were enriched in cytokine-cytokine receptor interaction,chemokine signaling pathway,metabolic pathways,PI3K-Akt signaling pathway,NF-kappa B signaling pathway,and other signaling pathways about cancer,while no down-regulated pathways were enriched.A PPI network of DEGs was constructed with 117 nodes and 660 edges,and 20 genes were selected as hub genes owing to high degrees in the *** to the Kaplan-Meier analysis,6 out of 20 hub genes including CCR7,FPR1,C3,CXCR5,GNB4,and PPBP with high mRNA expression were associated with poor OS for GC ***:The results of this study provide possible factors for the occurrence of GC,and the identification of the genes and pathways associated with the progression from GPL to GC provides valuable data for investigating the pathogenesis in future studies.

关键词： Gastric cancer Gastric precancerous lesions Integrated bioinformatics analysis Pathways Key genes Differentially expressed genes

Discussing the six meridional diseases of Shanghan Lun based on stress theory

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TMR Theory and Hypothesis 2019年第1期2卷 150-155页

作者： liang-jun yang Ya Li Dao-Rui Hou Zhi-Peng Hu Yong Zhang Pi-Wei institute Guangzhou University of Chinese MedicineGuangdongChina Obstetrics and Gynecology Department Lin’an Hospital of Traditional Chinese MedicineZhejiangChina Department of TCM Oncology The First People's Hospital of Xiangtan CityHunanChina School of Basic Medicine Chengdu University of Traditional Chinese MedicineChengduChina Pi-Wei department Sichuan Second Hospital of Traditional Chinese MedicineChengduSichuan China

As the theoretical source of Traditional Chinese Medicine clinical medicine,Shanghan Lun plays a vital role in guiding the diagnosis and treatment of clinical *** is a systemic nonspecific and adaptive response that occurs when the body is stimulated by internal and external environmental *** paper discusses the correlation between the three phases of stress containing alarm,resistance,and exhaustion and the three yin and three yang *** was concluded that sanyang diseases were related to the alarm stage and resistance stage,and sanyin diseases were related to the failure *** results indicated the essence of diseases of six meridians from the perspective of stress and provided reference for the diagnosis and treatment of six classics diseases.

关键词： Shanghan Lun Stress Six meridional diseases Three yin diseases Three yang diseases

A network pharmacology approach to investigate the mechanisms of Si-jun-Zi decoction in the treatment of gastric precancerous lesions

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Traditional Medicine Research 2018年第6期3卷 273-285页

作者： liang-jun yang Dao-Rui Hou Ya Li Zhi-Peng Hu Yong Zhang Guangzhou University of Chinese Medicine GuangzhouGuangdongChina The First People's Hospital of Xiangtan City XiangtanHunanChina Lin’an Hospital of Traditional Chinese Medicine Lin’anZhejiangChina Chengdu University of Traditional Chinese Medicine ChengduChina Sichuan Second Hospital of Traditional Chinese Medicine ChengduSichuan China

Objective:To find out the potential mechanisms of Si-jun-Zi(SJZ)decoction in the treatment of gastric precancerous lesions(GPL).Methods:A network pharmacology approach was used to analyze the active compounds,drug targets and interacting pathways of SJZ decoction in treating *** compounds and predicted targets of SJZ decoction were screened from TCMSP,and the disease targets were obtained from *** therapeutic mechanisms of action of the SJZ decoction were analyzed by gene ontology(GO)enrichment,Kyoto encyclopedia of genes and genomes pathway enrichment ***:The results show that 111 compounds and 90 targets were obtained in this *** targets were further mapped to 654 GO biological process terms and 21 remarkably *** compounds,targets,and pathways were used to construct a compound-target network,a target-pathways network,and an integrated GPL *** results indicated that SJZ decoction may treat the dysfunctions of GPL mainly from intervening in the mucosal inflammation,cell apoptosis process,and cell ***:This work provided a novel approach to understand the pathogenesis of GPL and revealed the therapeutic mechanisms of SJZ decoction,which facilitate the modernization of herbal medicine for complex diseases in the future.

关键词： Network pharmacology Gastric precancerous lesions Si-jun-Zi decoction Pathogenesis Traditional Chinese medicine

Two-step processed efficient perovskite solar cells via improving perovskite/PTAA interface using solvent engineering in PbI2 precursor

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Chinese Physics B 2020年第4期29卷 563-570页

作者： Cao-Yu Long Ning Wang Ke-Qing Huang Heng-Yue Li Biao Liu jun-liang yang Hunan Key Laboratory for Super-microstructure and Ultrafast Process School of Physics and ElectronicsCentral South UniversityChangsha 410083China

The morphology and interface of perovskite film are very important for the performance of perovskite solar cells(PSCs).The quality of perovskite film,fabricated via two-step spin-coating process,is significantly influenced by the morphology and crystallinity of PbI2 *** the addition of additive dimethyl sulfoxide(DMSO)into the PbI2 precursor,the roughness and trap-state density of perovskite film have been significantly reduced,leading to the excellent contact between perovskite layer and subsequent deposited carrier transport ***,the planar heterojunction PSCs with an architecture of ITO/SnO2/perovskite/PTAA/Ag show an efficiency up to 19.02%.Furthermore,PSCs exhibit promising stability in air with a humidity of ~45%,and retain 80% of initial efficiency after being exposed to air for 400 h without any encapsulation.

关键词： perovskite solar cells planar heterojunction interface PbI2-DMSO complex

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宽带压缩频谱感知非稀疏保护策略

华中科技大学学报（自然科学版） 2016年第9期44卷 32-37页

作者：刘玉磊梁俊肖楠杨萌空军工程大学信息与导航学院陕西西安710077 94755部队福建漳州363000

针对频谱非稀疏情况下宽带压缩频谱感知性能下降的问题,提出一种基于信号重构模型参数分析的频谱非稀疏保护策略,该策略根据次用户接收到的相邻三帧信号之间的相关系数的大小动态判断宽带压缩频谱感知正确与否.首先建立基于高斯分层概... 详细信息

针对频谱非稀疏情况下宽带压缩频谱感知性能下降的问题,提出一种基于信号重构模型参数分析的频谱非稀疏保护策略,该策略根据次用户接收到的相邻三帧信号之间的相关系数的大小动态判断宽带压缩频谱感知正确与否.首先建立基于高斯分层概率的宽带压缩信号模型对压缩重构进行分析,在此基础上综合考虑重构各帧信号模型参数的相关系数与频谱稀疏性之间的关系,设计一种认知用户能够根据信号模型参数相关系数的大小制定频谱稀疏与否的判决条件,进而制定保护措施.仿真结果表明:所提保护策略可以有效检测到由频谱非稀疏导致的宽带压缩频谱感知错误,降低对主用户的干扰概率.

关键词：认知无线电压缩频谱感知信号重构稀疏性相关系数干扰概率

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印度发展文化产业的经验及其借鉴

特区经济 2011年第12期 125-126页

作者：梁君杨霞深圳报业集团博士后工作站广东深圳518034 广西师范大学设计学院广西桂林541004

通过总结印度文化产业发展的成就和经验,在此基础上,有针对性的提出了我国文化产业发展策略。

关键词：文化产业经验策略