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4-46 An Experimental Design for Optimization in Some Data Matrices for the Mutant Metabolism Process

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IMP & HIRFL Annual Report 2016年第1期 166-170页

作者： zhou xiang Jiang Tingting liang jianping lu xihong Xin Zhijun li xuehu Wang liang 不详

Before applying the Response surface methodology(RSM)methodology,it is first necessary to choose an experimental design that will define which experiments should be carried out in the experimental region being *** are some experimental matrices for this *** designs for first-order models can be used when the data set does not present ***,to approximate a response function to experimental data that cannot be described by linear functions,experimental designs for quadratic response surfaces should be used,such as the approach to the applications of its more frequently used second-order experimental designs is broached,as well as the optimization of procedures that generate multiple responses.

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4-45 Retrospect and Prospect of Several Interesting Work of Heavy-ion Irradiation Drug

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IMP & HIRFL Annual Report 2016年第1期 163-166页

作者： liang jianping Wang liang Xin Zhijun li xuehu Du Wenyue lu xihong zhou xiang 不详

The world’s pharmaceutical industry is facing the shrink of new drug R&D investment,reduction of the number of new product approval and listed and patent expiration,and the drug production patterns are *** years of development,China has a very good accumulation on the drug *** the opportunities for change,how to use and play our advantage,breaking the barriers of large foreign pharmaceutical companies,become the key to the future development of China’s pharmaceutical *** ion irradiation drug production as a new method plays an important role both in the discovery of the structure of new drugs,high-quality traditional Chinese medicine and Resources of medicinal microorganisms.

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Influence of Carbon Ion Irradiation on Phenolic,Antioxidants and Antibacterial Activity of Isatis indigotica Fort

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IMP & HIRFL Annual Report 2018年第1期 131-131页

作者： liang jianping li xuehu lu xihong Xin Zhijun zhou xiang 不详

The heavy ions beam radiation increases the activity of the Peroxidases,an enzyme responsible for the biosynthesis of phenolic compounds,indicating significant change in the chemical composition[1].This fact explains ... 详细信息

关键词： phenolic herbal Carbon

3 - 104 M1 Biological Effects of lsatis indigotica Fort Irradiated by 12C6＋ Ions

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IMP & HIRFL Annual Report 2013年第1期 172-172页

作者： liang jianping li xuehu lu xihong Xin Zhijun zhou xiang

3 - 105 Effect of 12C6d- Ion Beam Irradiation on Physiological Characteristics of Isatis indigotica Fort

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IMP & HIRFL Annual Report 2013年第1期 173-173页

作者： li xuehu lu xihong liang jianping Xin Zhijun zhou xiang

3-81 Enhancement of Bioproduction of Butyrate by Heavy-ion Irradiation

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IMP & HIRFL Annual Report 2014年第1期 174-174页

作者： zhou xiang liang jianping lu xihong li xuehu Xin Zhijun Wang liang Du Wenyue Wu Zhengqian 不详

Butyric acid as a renewable resource has become an increasingly attractive alternative to petroleum based *** tyrobutyricum is well documented as a fermentation strain for the production of acids. However, it hasbeen reported that butyrate inhibits its growth, and the accumulation of acetate also inhibits biomass synthesis,making production of butyric acid from conventional fermentation processes economically challenging. The presentstudy aimed to identify whether irradiation of C. tyrobutyricum cells makes them more tolerant to butyric acidinhibition and increases the production of butyrate compared with wild type.

关键词： Enhancement Bioproduction Butyrate

3-80 Heavy-ion Irradiation Drug Development in Retrospect and Prospect

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IMP & HIRFL Annual Report 2014年第1期 173-173页

作者： zhou xiang liang jianping lu xihong li xuehu Xin Zhijun Wang liang Du Wenyue Wu Zhengqian 不详

The world is facing severe challenges of sustainable development, which requires the joint effort of the globalscience community to solve. As China continues to grow at a very impressive pace, the state appears acutely awareof the need to expand the Chinese science and technology portfolio to help fuel its growth and keep it *** also needs to continue on the path to innovations and modernization, focusing on endogenous growth torealize full, coordinated, and sustainable development.

关键词： Irradiation Drug Development