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Development of a soft X-ray microprobe for single cell radiobiology

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Nuclear Science and Techniques 2009年第2期20卷 82-86页

作者： CHEN liang YAN Jingwen jiang Shiping YU Yang National Synchrotron Radiation Laboratory University of Science ＆ Technology of China Hefei 230029 China

An X-ray microprobe for radiobiological studies was developed which deliver precise doses of radiation to the selected individual *** facility used synchrotron radiation as soft X-ray source.A zone plate combining with a pinhole produced a fine probe from bending magnet for single cell irradiating with defined *** diameter of microprobe at the target position was about 2 μm by scanning a knife-edge with an AXUV photo *** fluxes of soft X-rays at 516.7 eV(2.4 nm) were about 5.4×104 photons/s.100mA measured with the photo *** absorbed dose rate for typical yeast cells was about 11.34 Gy/s with the storage current of 100 mA.A preliminary experiment for yeast cells irradiation has shown that the microprobe had a definite biological effect for radiobiological *** soft X-ray microprobe at "water window" region has provided a useful tool for single cell irradiating damage and a capability of individually irradiating a certain numbers of cells each time.

关键词： X射线微探针放射生物学单细胞软X射线源辐射生物学效应光电二极管照射剂量同步辐射

CONTROL OF DIMENSIONAL STABILITY AND DEGRADATION RATE IN ELECTROSPUN COMPOSITE SCAFFOLDS COMPOSED OF POLY(D,L-LACTIDE-co-GLYCOLIDE) AND POLY(ε-CAPROLACTONE)

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Chinese Journal of Polymer Science 2008年第1期26卷 63-71页

作者： Yi-jie Liu Hong-liang jiang Yan Li Kang-jie Zhu Department of Polymer Science and Engineering Zhejiang UniversityHangzhou 310027China

The purpose of this study is to investigate the effect of composition poly(D,L-lactide-co-glycolide)/poly(ε- caprolactone)(PLGA/PCL)blending on the morphology,shrinkage and degradation behaviors of the electrospun fibers. With the increase of PLGA content in the composite fibers,the average diameter of the electrospun fibers increased from 1.35μm to 1.95μ*** serious shrinking of the electrospun PLGA meshes could be circumvented by adding 20% PCL in the fibers,resulting from the semi-crystalline nature of ...

关键词： Electrospun PCL PLGA Shrinkage Degradation

Exploring the role of --NH2 functional groups of ethylenediamine in chemical mechanical polishing of GCr15 bearing steel

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Friction 2021年第6期9卷 1673-1687页

作者： Hanqiang WU liang jiang Xia ZHONG Jinwei LIU Na QIN Linmao QIAN Tribology Research Institute State Key Laboratory of Traction PowerSouthwest Jiaotong UniversityChengdu 610031China School of Mechanical Engineering Southwest Jiaotong UniversityChengdu 610031China

Ethylenediamine with two-NH2 functional groups was used as a critical complexing agent in chemical mechanical polishing(CMP)slurries for a high carbon chromium GCr15 bearing steel(equivalent to AISI 52100).The polishing performance and corresponding mechanism of-NH2 functional groups were thoroughly investigated as a function of *** is revealed that,when polished with ethylenediamine and H2O2-based slurries,the material removal rate(MRR)and surface roughness Ra of GCr15 steel gradually decrease as pH *** with acidic pH of 4.0,at alkaline pH of 10.0,the surface film of GCr15 steel has much higher corrosion resistance and wear resistance,and thus the material removal caused by the pure corrosion and corrosion-enhanced wear are greatly inhibited,resulting in much lower MRR and ***,it is confirmed that a more protective composite film,consisting of more Fe3+hydroxides/oxyhydroxides and complex compounds with-NH2 functional groups of ethylenediamine,can be formed at pH of ***,the polishing performance of pure iron and a medium carbon 45 steel exhibits a similar trend as GCr15 *** findings suggest that acidic pH could be feasible for amine groups-based complexing agents to achieve efficient CMP of iron-based metals.

关键词： chemical mechanical polishing(CMP) complexing agent bearing steel

儿科经典名方异功散的历史沿革与关键信息考证

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中国实验方剂学杂志 2024年第7期30卷 205-214页

作者：苏江敏章军郭丛赵桉熠姜亮张恒邸继鹏陈莎刘丽刘艳刘安中国中医科学院中药研究所北京100700 山东仙河药业有限公司山东东营257231

异功散出自北宋·钱乙《小儿药证直诀》,为国家中医药管理局2022年9月发布的《古代经典名方目录(第二批儿科部分)》中的第3号方,可开发为3.1类中药新药。该研究通过查阅古代医籍和现代文献,从异功散的历史沿革、药味基原和炮制、剂量折... 详细信息

异功散出自北宋·钱乙《小儿药证直诀》,为国家中医药管理局2022年9月发布的《古代经典名方目录(第二批儿科部分)》中的第3号方,可开发为3.1类中药新药。该研究通过查阅古代医籍和现代文献,从异功散的历史沿革、药味基原和炮制、剂量折算、制法用法、功能应用5个方面进行考证,形成该处方的关键信息表,以期为异功散基准样品研制和制剂开发提供参考。依据研究结果,建议异功散药材基原和炮制选用人参Panax ginseng去芦,茯苓Poria cocos去皮,甘草应为乌拉尔甘草Glycyrrhiza uralensis,陈皮Citrus reticulata切丝。剂量折算分别按4.13 g/钱、生姜1 g/片、大枣3 g/个、体积300 mL/盏折算,每服处方药味中人参、茯苓、白术、甘草、陈皮各1.652 g,生姜5 g、大枣6 g,总量为19.26 g;煎煮方法为药味粉碎成50~80目细末,每服加水300 mL,煎至210 mL,去滓食前温服。该方古籍记载主治脾胃虚寒气滞之小儿吐泻不思饮食,经后世医家临证灵活应用,常用于治疗小儿厌食症、消化道炎症、腹泻等疾病。

关键词：经典名方处方考证异功散四君子汤历史沿革中药煮散儿科疾病

Microwave Synthesis of Au Nanoparticles with the System of AuCl_4-CH_3CH_2OH

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Chinese Chemical Letters 2001年第6期12卷 551-554页

作者： Zhi liang jiang Zhong Wei FENG Xing Can SHEN Institution of New Technology and Material Guang Xi Normal UniversityGuilin 541004

The Au nanoparticles has been prepared by microwave high-pressure procedure with alcohol as the reducing agent. The color of colloidal Au nanoparticles is blue-violet. The maximum absorption spectrum of colloidal Au is at 580 nm, and the resonance scattering peak is at 580 nm. Using this method, the colloidal Au of long-time stability can be prepared Simply and quickly.

关键词： Microwave high-pressure alcohol Au nanoparticles resonance scattering spectroscopy(RSS)

Effect of oxide film on nanoscale mechanical removal of pure iron

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Friction 2018年第3期6卷 307-315页

作者： Jinwei LIU liang jiang Changbang DENG Wenhao DU Linmao QIAN Tribology Research Institute State Key Laboratory of Traction Power Southwest Jiaotong University Institute of Machinery Manufacturing Technology China Academy of Engineering Physics

In this paper, the properties of an oxide film formed on a pure iron surface after being polished with an H2O-based acidic slurry were investigated using an atomic force microscope （AFM）, Auger electron spectroscopy （AES）, and angle-resolved X-ray photoelectron spectroscopy （AR-XPS） to partly reveal the material removal mechanism of pure iron during chemical mechanical polishing （CMP）. The AFM results show that, when rubbed against a cone-shaped diamond tip in vacuum, the material removal depth of the polished pure iron first slowly increases to 0.45 nm with a relatively small slope of 0.11 nm/μN as the applied load increases from 0 to 4 μN, and then rapidly increases with a large slope of 1.98 nm/μN when the applied load further increases to 10 μN. In combination with the AES and AR-XPS results, a layered oxide film with approximately 2 nm thickness （roughly estimated from the sputtering rate） is formed on the pure iron surface. Moreover, the film can be simply divided into two layers, namely. an outer layer and an inner layer. The outer layer primarily consists of FeOOH （most likely α-FeOOH） and possibly Fe2O3 with a film thickness ranging from 0.36 to 0.48 nm （close to the 0.45 nm material removal depth at the 4 μN turning point）, while the inner layer primarily consists of Fe304. The mechanical strength of the outer layer is much higher than that of the inner layer. Moreover, the mechanical strength of the inner layer is quite close to that of the pure iron substrate. However, when a real CMP process is applied to pure iron, pure mechanical wear by silica particles generates almost no material removal due to the extremely high mechanical strength of the oxide film. This indicates that other mechanisms, such as in-situ chemical corrosion-enhanced mechanical wear, dominate the CMP process.

关键词： oxide film nanoscale mechanical removal pure iron chemical mechanical polishing

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飞机燃油系统闪电试验可燃气体配比研究

海军航空大学学报 2024年第1期39卷 167-172页

作者：姜亮刘春阳姚永杰熊秀中国商用飞机有限责任公司上海飞机设计研究院上海201210 中国民用航空上海航空器适航审定中心上海200335 西安爱邦电磁技术有限责任公司陕西西安710077

飞机燃油系统闪电试验中,可燃气体混合配比体积分数的轻微变化对气体的点燃能量和点燃概率有重要的影响。采用混合配比体积分数不恰当的可燃气体可能会导致闪电试验欠考核或过严考核,进而影响对闪电防护设计有效性的准确评估。采用高精... 详细信息

飞机燃油系统闪电试验中,可燃气体混合配比体积分数的轻微变化对气体的点燃能量和点燃概率有重要的影响。采用混合配比体积分数不恰当的可燃气体可能会导致闪电试验欠考核或过严考核,进而影响对闪电防护设计有效性的准确评估。采用高精度的动态气体配比调控系统搭建了可燃气体点燃试验验证台架,通过试验对不同可燃气体配比体积分数下的最小点燃能量及相关点燃影响因素进行了研究和分析。研究表明:采用5.0%氢气配比体积分数的可燃气体可检出200μJ及以上能量的全部点火源,同时可避免闪电试验被过度考核,推荐进行优先选配;随着氢气配比体积分数的增大,可燃气体点燃所需的点燃能量逐渐降低;氢气配比体积分数越高,燃油系统闪电试验被过度考核的程度就越大;鉴于可燃气体燃爆冲击的安全影响,不推荐燃油系统闪电试验采用6.5%及以上氢气配比体积分数的可燃气体。试验数据及研究结论可为飞机燃油系统闪电防护设计及闪电试验提供参考和指导。

关键词：飞机燃油系统闪电可燃气体

Shaking table tests on a cantilever retaining wall with reinforced and unreinforced backfill

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2022年第11期23卷 900-916页

作者： Ming WEI Qiang LUO Gui-shuai FENG Teng-fei WANG liang-wei jiang School of Civil Engineering Southwest Jiaotong UniversityChengdu 610031China MOE Key Laboratory of High-Speed Railway Engineering Chengdu 610031China

Physical modelling of cantilever retaining walls with and without backfill reinforcement was conducted on a 1g shaking table to evaluate the mitigation effect of reinforcement on system dynamics(g denotes the acceleration of gravity).The model wall has a height of 1.5 m with a scale ratio of 1/4 and retains dry sand *** input motions are amplified to three levels of input peak base acceleration,0.11g,0.24g,and 0.39g,corresponding to minor,moderate,and major earthquakes,*** of the seismic response of the retaining walls focuses on acceleration and lateral displacement of the wall and backfill,dynamic earth pressures,and tensile load in the reinforcements(modeled by phosphor-bronze strips welded into a mesh).The inclusion of reinforcement has been observed to improve the integrity of the wall-soil system,mitigate vibration-related damage,and reduce the fundamental frequency of a reinforced *** of acceleration from the base to the upper portion is accompanied by time delay and nonlinear amplification.A reinforced system with a lower acceleration amplification factor than the unreinforced one indicates that reinforcement can reduce the amplification effect of input *** minor and moderate earthquake loadings,reinforcement allows the inertia force and seismic earth pressure to be asynchronous and decreases the seismic earth pressure when inertia forces *** major earthquake loading,the wall is displaced horizontally less than the backfill,with soil pushing the wall substantially;the effect of backfill reinforcement has not been fully *** dynamic earth pressure is large at the top and diminishes toward the bottom.

关键词： Cantilever retaining wall Backfill reinforcement Seismic response Shaking table test Dynamic earth pressure Phase shift

Advances in Triboelectric Nanogenerators for Blue Energy Harvesting and Marine Environmental Monitoring

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Engineering 2024年第2期33卷 204-224页

作者： Yang jiang Xi liang Tao jiang Zhong Lin Wang CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro–Nano Energy and SensorsBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 101400China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing 100049China Georgia Institute of Technology AtlantaGA 30332USA

Blue energy,which includes rainfall,tidal current,wave,and water-flow energy,is a promising renewable resource,although its exploitation is limited by current technologies and thus remains *** form of energy is mainly harvested by electromagnetic generators(EMGs),which generate electricity via Lorenz force-driven electron *** nano genera tors(TENGs)and TENG networks exhibit superiority over EMGs in low-frequency and high-entropy energy harvesting as a new approach for blue energy harvesting.A TENG produces electrical outputs by adopting the mechanism of Maxwell’s displacement *** date,a series of research efforts have been made to optimize the structure and performance of TENGs for effective blue energy harvesting and marine environmental *** the great progress that has been achieved in the use of TENGs in this context so far,continuous exploration is required in energy conversion,device durability,power management,and environmental *** review reports on advances in TENGs for blue energy harvesting and marine environmental *** introduces the theoretical foundations of TENGs and discusses advanced TENG prototypes for blue energy harvesting,including TENG structures that function in freestanding and contact-separation *** enhancement strategies for TENGs intended for blue energy harvesting are also ***,marine environmental applications of TENGs based on blue energy harvesting are discussed.

关键词： Triboelectric nanogenerator TENG networks Blue energy Energy harvesting Ocean sensors